1. Lymphocyte-rich pleural liposarcoma mimicking pericardial cyst
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Tawfiqul Bhuiya, Mobeen Iqbal, Harry Steinberg, Rudy P. Lackner, Jeffrey Posen, and Leonard J. Rossoff
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Male ,Pulmonary and Respiratory Medicine ,medicine.medical_specialty ,Pleural Neoplasms ,Physical examination ,Liposarcoma ,Chest pain ,Diagnosis, Differential ,Pleural disease ,medicine ,Humans ,Pericardium ,Cyst ,Lymphocytes ,Pleural Neoplasm ,neoplasms ,Aged ,medicine.diagnostic_test ,business.industry ,respiratory system ,medicine.disease ,Surgery ,respiratory tract diseases ,body regions ,medicine.anatomical_structure ,Mediastinal Cyst ,medicine.symptom ,business ,Chest radiograph ,Cardiology and Cardiovascular Medicine - Abstract
cyte-rich pleural liposarcoma, which mimicked a pericardial cyst on computed tomographic (CT) scan. Histopathologic examination revealed a recently described lymphocytic-rich variant, which might be mistaken for lymphoma.3 Clinical summary. A 78-year-old white man with a 40 pack-year history of smoking was seen for an asymptomatic opacity detected on a routine chest x-ray film. A chest radiograph 4 months earlier had shown no abnormalities. His medical history was significant for controlled atrial fibrillation, adult-onset diabetes mellitus, hypertension, and benign prostatic enlargement. He specifically denied cough, chest pain, and all constitutional symptoms. He reported dyspnea on moderate exertion, which had been stable for many months. His medications included lisinopril, metformin, digoxin, doxazosin mesylate, aspirin, and felodipine. On physical examination, vital signs were within normal limits and no adenopathy or jugular venous distention was detected. Examination of the chest was unremarkable, as was the rest of the physical examination. The chest radiograph revealed an opacity abutting the lower right border of the heart (Fig 1, A). A CT scan of the chest revealed a cystic opacity in the major fissure, apparently attached to the pericardium. The location and CT appearance were suggestive of a pericardial Liposarcomas are the second most common histologic type of soft tissue sarcomas.1 Common sites of involvement include the lower extremities and retroperitoneum. Primary intrathoracic liposarcomas are rare with a preference for the mediastinum.1 Very few cases of primary involvement of lung and pericardium have been reported, including only 9 cases of pleural liposarcomas.2 We review a unique case of lymphoLYMPHOCYTE-RICH PLEURAL LIPOSARCOMA MIMICKING PERICARDIAL CYST
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