1. Genome Sequence of the Plant Pathogen and Biotechnology Agent Agrobacterium tumefaciens C58
- Author
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Oleg Iartchouk, Casey M Flanagan, Jordan Gurson, Clifford Wollam, Charlaine Scott, Yongwei Cao, Andrew Epp, Steven C. Slater, Stacie Gattung, Chris B. Crowell, Lori Mullin, Courtney M. Lappas, Nancy M. Miller, Fang Liu, Kathryn L. Houmiel, Carolyn Sear, Dahlia Doughty, Barry S. Goldman, Mike Allinger, Manor Askenazi, Graham Strub, Mary Blanchard, Brian P. Markelz, Conrad Halling, Caroline Lomo, Barbara A. Qurollo, Jeffrey M. Gordon, Mark Vaudin, Chris Cielo, Gregory Hinkle, and Brad Goodner
- Subjects
Genetics ,Transfer DNA ,Whole genome sequencing ,Multidisciplinary ,fungi ,food and beverages ,Virulence ,Agrobacterium tumefaciens ,Biology ,biology.organism_classification ,Genome ,Plasmid ,Gall ,Gene - Abstract
Agrobacterium tumefaciens is a plant pathogen capable of transferring a defined segment of DNA to a host plant, generating a gall tumor. Replacing the transferred tumor-inducing genes with exogenous DNA allows the introduction of any desired gene into the plant. Thus, A. tumefaciens has been critical for the development of modern plant genetics and agricultural biotechnology. Here we describe the genome of A. tumefaciens strain C58, which has an unusual structure consisting of one circular and one linear chromosome. We discuss genome architecture and evolution and additional genes potentially involved in virulence and metabolic parasitism of host plants.
- Published
- 2001