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1. Genetic mapping of the mouse proto-oncogene c-sis to chromosome 15.

Author

Kozak CA, Sears JF, and Hoggan MD

Subjects
Animals, Chromosome Aberrations genetics, Chromosome Disorders, Chromosome Mapping, Mice, Nucleic Acid Hybridization, Leukemia, Experimental genetics, Oncogenes, Retroviridae genetics, Sarcoma Virus, Woolly Monkey genetics
Abstract

The mouse homolog (c-sis) of the transforming gene of the simian sarcoma virus was mapped to chromosome 15 by the Southern blot analysis of DNA's from hamster-mouse somatic cell hybrids. Alterations in c-sis expression may thus play a role in the various murine neoplastic diseases characterized by rearrangements or duplications of chromosome 15.

Published
1983
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