1. A role for bacterial urease in gut dysbiosis and Crohn's disease.
- Author
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Ni, Josephine, David Shen, Ting-Chin, Chen, Eric Z., Bittinger, Kyle, Bailey, Aubrey, Roggiani, Manuela, Sirota-Madi, Alexandra, Friedman, Elliot S., Chau, Lillian, Lin, Andrew, Nissim, Ilana, Scott, Justin, Lauder, Abigail, Hoffmann, Christopher, Rivas, Gloriany, Albenberg, Lindsey, Baldassano, Robert N., Braun, Jonathan, Xavier, Ramnik J., and Clish, Clary B.
- Subjects
BACTERIA ,CROHN'S disease ,AMINO acids ,INFLAMMATION ,PROTEOBACTERIA ,PATIENTS - Abstract
The article analysis the relation between disease severity, gut dysbiosis, and bacterial production of free amino acids in Crohn's disease patients. Topics discussed include role of intestinal inflammation in developing dysbiosis and chronic alteration of the gut microbiota; association of amino acids in fecal microbiota with disease activity; and association of fecal amino acids with proteobacteria in pediatric patients with Crohn's disease.
- Published
- 2017
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