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Start Over Author "Wu, Xiaolin" Publisher american association for cancer research (aacr)
35 results on '"Wu, Xiaolin"'

1. Abstract A006: Reckless mitotic entry as a novel chemosensitization approach for alkylating agents

Author

Lang, Fengchao, primary, Cornwell, James, additional, Kaur, Karambir, additional, Elmogazy, Omar, additional, Zhang, Wei, additional, Zhang, Meili, additional, Song, Hua, additional, Sun, Zhonghe, additional, Wu, Xiaolin, additional, Aladjem, Mirit I., additional, Aregger, Michael, additional, Cappell, Steven, additional, and Yang, Chunzhang, additional

Published
2024
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2. Data from Phase I Study and Cell-Free DNA Analysis of T-DM1 and Metronomic Temozolomide for Secondary Prevention of HER2-Positive Breast Cancer Brain Metastases

Author

Jenkins, Sarah, primary, Zhang, Wei, primary, Steinberg, Seth M., primary, Nousome, Darryl, primary, Houston, Nicole, primary, Wu, Xiaolin, primary, Armstrong, Terri S., primary, Burton, Eric, primary, Smart, Dee Dee, primary, Shah, Ritu, primary, Peer, Cody J., primary, Mozarsky, Brett, primary, Arisa, Oluwatobi, primary, Figg, William D., primary, Mendoza, Tito R., primary, Vera, Elizabeth, primary, Brastianos, Priscilla, primary, Carter, Scott, primary, Gilbert, Mark R., primary, Anders, Carey K., primary, Connolly, Roisín M., primary, Tweed, Carol, primary, Smith, Karen L., primary, Khan, Imran, primary, Lipkowitz, Stanley, primary, Steeg, Patricia S., primary, and Zimmer, Alexandra S., primary

Published
2023
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3. Supplementary Data 1 from Phase I Study and Cell-Free DNA Analysis of T-DM1 and Metronomic Temozolomide for Secondary Prevention of HER2-Positive Breast Cancer Brain Metastases

Author

Jenkins, Sarah, primary, Zhang, Wei, primary, Steinberg, Seth M., primary, Nousome, Darryl, primary, Houston, Nicole, primary, Wu, Xiaolin, primary, Armstrong, Terri S., primary, Burton, Eric, primary, Smart, Dee Dee, primary, Shah, Ritu, primary, Peer, Cody J., primary, Mozarsky, Brett, primary, Arisa, Oluwatobi, primary, Figg, William D., primary, Mendoza, Tito R., primary, Vera, Elizabeth, primary, Brastianos, Priscilla, primary, Carter, Scott, primary, Gilbert, Mark R., primary, Anders, Carey K., primary, Connolly, Roisín M., primary, Tweed, Carol, primary, Smith, Karen L., primary, Khan, Imran, primary, Lipkowitz, Stanley, primary, Steeg, Patricia S., primary, and Zimmer, Alexandra S., primary

Published
2023
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4. Figure S1 from Phase I Study and Cell-Free DNA Analysis of T-DM1 and Metronomic Temozolomide for Secondary Prevention of HER2-Positive Breast Cancer Brain Metastases

Author

Jenkins, Sarah, primary, Zhang, Wei, primary, Steinberg, Seth M., primary, Nousome, Darryl, primary, Houston, Nicole, primary, Wu, Xiaolin, primary, Armstrong, Terri S., primary, Burton, Eric, primary, Smart, Dee Dee, primary, Shah, Ritu, primary, Peer, Cody J., primary, Mozarsky, Brett, primary, Arisa, Oluwatobi, primary, Figg, William D., primary, Mendoza, Tito R., primary, Vera, Elizabeth, primary, Brastianos, Priscilla, primary, Carter, Scott, primary, Gilbert, Mark R., primary, Anders, Carey K., primary, Connolly, Roisín M., primary, Tweed, Carol, primary, Smith, Karen L., primary, Khan, Imran, primary, Lipkowitz, Stanley, primary, Steeg, Patricia S., primary, and Zimmer, Alexandra S., primary

Published
2023
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5. Supplementary Data from Genome-Wide RNAi Screen Identifies PMPCB as a Therapeutic Vulnerability in EpCAM+ Hepatocellular Carcinoma

Author

Takai, Atsushi, primary, Dang, Hien, primary, Oishi, Naoki, primary, Khatib, Subreen, primary, Martin, Sean P., primary, Dominguez, Dana A., primary, Luo, Ji, primary, Bagni, Rachel, primary, Wu, Xiaolin, primary, Powell, Katie, primary, Ye, Qing-Hai, primary, Jia, Hu-Liang, primary, Qin, Lun-Xiu, primary, Chen, Jinqiu, primary, Mitchell, Gary A., primary, Luo, Xiaoling, primary, Thorgeirsson, Snorri S., primary, and Wang, Xin Wei, primary

Published
2023
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6. Supplementary Table S1 from Accelerated Preclinical Testing Using Transplanted Tumors from Genetically Engineered Mouse Breast Cancer Models

Author

Varticovski, Lyuba, primary, Hollingshead, Melinda G., primary, Robles, Ana I., primary, Wu, Xiaolin, primary, Cherry, James, primary, Munroe, David J., primary, Lukes, Luanne, primary, Anver, Miriam R., primary, Carter, John P., primary, Borgel, Suzanne D., primary, Stotler, Howard, primary, Bonomi, Carrie A., primary, Nunez, Nomelí P., primary, Hursting, Stephen D., primary, Qiao, Wenhui, primary, Deng, Chuxia X., primary, Green, Jeff E., primary, Hunter, Kent W., primary, Merlino, Glenn, primary, Steeg, Patricia S., primary, Wakefield, Lalage M., primary, and Barrett, J. Carl, primary

Published
2023
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7. Data from Genome-Wide RNAi Screen Identifies PMPCB as a Therapeutic Vulnerability in EpCAM+ Hepatocellular Carcinoma

Author

Takai, Atsushi, primary, Dang, Hien, primary, Oishi, Naoki, primary, Khatib, Subreen, primary, Martin, Sean P., primary, Dominguez, Dana A., primary, Luo, Ji, primary, Bagni, Rachel, primary, Wu, Xiaolin, primary, Powell, Katie, primary, Ye, Qing-Hai, primary, Jia, Hu-Liang, primary, Qin, Lun-Xiu, primary, Chen, Jinqiu, primary, Mitchell, Gary A., primary, Luo, Xiaoling, primary, Thorgeirsson, Snorri S., primary, and Wang, Xin Wei, primary

Published
2023
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8. Supplementary Data from The NCI Transcriptional Pharmacodynamics Workbench: A Tool to Examine Dynamic Expression Profiling of Therapeutic Response in the NCI-60 Cell Line Panel

Author

Monks, Anne, primary, Zhao, Yingdong, primary, Hose, Curtis, primary, Hamed, Hossein, primary, Krushkal, Julia, primary, Fang, Jianwen, primary, Sonkin, Dmitriy, primary, Palmisano, Alida, primary, Polley, Eric C., primary, Fogli, Laura K., primary, Konaté, Mariam M., primary, Miller, Sarah B., primary, Simpson, Melanie A., primary, Voth, Andrea Regier, primary, Li, Ming-Chung, primary, Harris, Erik, primary, Wu, Xiaolin, primary, Connelly, John W., primary, Rapisarda, Annamaria, primary, Teicher, Beverly A., primary, Simon, Richard, primary, and Doroshow, James H., primary

Published
2023
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9. Supplementary Figure Legend from Accelerated Preclinical Testing Using Transplanted Tumors from Genetically Engineered Mouse Breast Cancer Models

Author

Varticovski, Lyuba, primary, Hollingshead, Melinda G., primary, Robles, Ana I., primary, Wu, Xiaolin, primary, Cherry, James, primary, Munroe, David J., primary, Lukes, Luanne, primary, Anver, Miriam R., primary, Carter, John P., primary, Borgel, Suzanne D., primary, Stotler, Howard, primary, Bonomi, Carrie A., primary, Nunez, Nomelí P., primary, Hursting, Stephen D., primary, Qiao, Wenhui, primary, Deng, Chuxia X., primary, Green, Jeff E., primary, Hunter, Kent W., primary, Merlino, Glenn, primary, Steeg, Patricia S., primary, Wakefield, Lalage M., primary, and Barrett, J. Carl, primary

Published
2023
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11. Data from The NCI Transcriptional Pharmacodynamics Workbench: A Tool to Examine Dynamic Expression Profiling of Therapeutic Response in the NCI-60 Cell Line Panel

Author

Monks, Anne, primary, Zhao, Yingdong, primary, Hose, Curtis, primary, Hamed, Hossein, primary, Krushkal, Julia, primary, Fang, Jianwen, primary, Sonkin, Dmitriy, primary, Palmisano, Alida, primary, Polley, Eric C., primary, Fogli, Laura K., primary, Konaté, Mariam M., primary, Miller, Sarah B., primary, Simpson, Melanie A., primary, Voth, Andrea Regier, primary, Li, Ming-Chung, primary, Harris, Erik, primary, Wu, Xiaolin, primary, Connelly, John W., primary, Rapisarda, Annamaria, primary, Teicher, Beverly A., primary, Simon, Richard, primary, and Doroshow, James H., primary

Published
2023
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12. Supplementary Figures S1-S4 from Accelerated Preclinical Testing Using Transplanted Tumors from Genetically Engineered Mouse Breast Cancer Models

Author

Varticovski, Lyuba, primary, Hollingshead, Melinda G., primary, Robles, Ana I., primary, Wu, Xiaolin, primary, Cherry, James, primary, Munroe, David J., primary, Lukes, Luanne, primary, Anver, Miriam R., primary, Carter, John P., primary, Borgel, Suzanne D., primary, Stotler, Howard, primary, Bonomi, Carrie A., primary, Nunez, Nomelí P., primary, Hursting, Stephen D., primary, Qiao, Wenhui, primary, Deng, Chuxia X., primary, Green, Jeff E., primary, Hunter, Kent W., primary, Merlino, Glenn, primary, Steeg, Patricia S., primary, Wakefield, Lalage M., primary, and Barrett, J. Carl, primary

Published
2023
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21. Phase I Study and Cell-Free DNA Analysis of T-DM1 and Metronomic Temozolomide for Secondary Prevention of HER2-Positive Breast Cancer Brain Metastases

Author

Jenkins, Sarah, primary, Zhang, Wei, additional, Steinberg, Seth M., additional, Nousome, Darryl, additional, Houston, Nicole, additional, Wu, Xiaolin, additional, Armstrong, Terri S., additional, Burton, Eric, additional, Smart, DeeDee, additional, Shah, Ritu, additional, Peer, Cody J., additional, Mozarsky, Brett, additional, Arisa, Oluwatobi, additional, Figg, William D., additional, Mendoza, Tito R., additional, Vera, Elizabeth, additional, Brastianos, Priscilla, additional, Carter, Scott, additional, Gilbert, Mark R., additional, Anders, Carey K., additional, Connolly, Roisin M., additional, Tweed, Carol, additional, Smith, Karen L., additional, Khan, Imran, additional, Lipkowitz, Stanley, additional, Steeg, Patricia S., additional, and Zimmer, Alexandra S., additional

Published
2023
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23. Abstract 4611: A multicenter clinical study of stool DNA test of methylated syndecan-2 for colorectal cancer detection

Author

Wang, Jianping, primary, Liu, Side, additional, Wang, Hui, additional, Zheng, Lei, additional, Zhou, Changchun, additional, Li, Guoxin, additional, Huang, Rongkang, additional, Wang, Huaiming, additional, Li, Chujun, additional, Fan, Xinjuan, additional, Fu, Xinhui, additional, Wang, Xinying, additional, Guo, Hongliang, additional, Guan, Jie, additional, Sun, Yanlai, additional, Song, Xilin, additional, Li, Zengjun, additional, Mu, Dianbin, additional, Sun, Jujie, additional, Liu, Xianglin, additional, Qi, Yan, additional, Niu, Feng, additional, Chen, Chunhua, additional, Wu, Xiaolin, additional, Wang, Xianshu, additional, Song, Xianrang, additional, and Zou, Hongzhi, additional

Published
2020
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25. Abstract 4611: A multicenter clinical study of stool DNA test of methylated syndecan-2 for colorectal cancer detection

Author

Hongliang Guo, Yanlai Sun, Yan Qi, Guoxin Li, Huaiming Wang, Wu Xiaolin, Chujun Li, Jie Guan, Changchun Zhou, Xianrang Song, Rongkang Huang, Xinjuan Fan, Dianbin Mu, Zengjun Li, Xianshu Wang, Xilin Song, Feng Niu, Xinying Wang, Xianglin Liu, Jianping Wang, Xinhui Fu, Jujie Sun, Side Liu, Lei Zheng, Hongzhi Zou, Hui Wang, and Chunhua Chen

Subjects
Cancer Research, medicine.medical_specialty, medicine.diagnostic_test, business.industry, Colorectal cancer, Cancer, Colonoscopy, medicine.disease, Gastroenterology, Test (assessment), Clinical study, Oncology, Internal medicine, medicine, Stool dna, Tumor location, Stage (cooking), business
Abstract

Study purpose: Previously, we had a pilot study to evaluate the feasibility of a stool DNA test of methylated Syndycan-2 (SDC2) for colorectal cancer (CRC) detection. The purpose of this continuing investigation was to assess the performance of this test in a multicenter hospital-based setting. Methods: Each participant was required to undergo both a stool DNA test and a reference colonoscopy. The stool DNA test assesses the methylation status of a single target of SDC2 gene. Results of real-time methylation-specific PCR were dichotomized as positive and negative by a prespecified cut-off value. The main evaluation indexes were sensitivity, specificity, and kappa value, which was used to assess the diagnostic consistency between stool DNA test and colonoscopy. Tests were performed in blinded fashion and processed independently of the colonoscopic results. Results: Among the 1110 participants from three hospitals included for analysis, 359 and 38 had CRC and advanced adenomas, respectively, according to colonoscopy findings. The sensitivity of the stool DNA test was 83.8% for CRC and 42.1% for advanced adenomas. For CRC at early stage confined to bowel wall (I to II), the sensitivity was 87.0%. Detection rate for CRC did not vary significantly according to age, tumor location, differentiation, and TNM stage, except for gender (P=0.041). The specificity of the stool DNA test was 98.0% among participants with nonadvanced colorectal neoplasia, non-neoplastic disorders, or negative results on colonoscopy. Diagnostic consistency for CRC assessed by kappa value was 0.84, indicating that the agreement in outcome between the stool DNA test and colonoscopy was excellent. Conclusion: Noninvasive stool DNA test using methylated SDC2 as a molecular marker was a sensitive and accurate method for CRC detection. Citation Format: Jianping Wang, Side Liu, Hui Wang, Lei Zheng, Changchun Zhou, Guoxin Li, Rongkang Huang, Huaiming Wang, Chujun Li, Xinjuan Fan, Xinhui Fu, Xinying Wang, Hongliang Guo, Jie Guan, Yanlai Sun, Xilin Song, Zengjun Li, Dianbin Mu, Jujie Sun, Xianglin Liu, Yan Qi, Feng Niu, Chunhua Chen, Xiaolin Wu, Xianshu Wang, Xianrang Song, Hongzhi Zou. A multicenter clinical study of stool DNA test of methylated syndecan-2 for colorectal cancer detection [abstract]. In: Proceedings of the Annual Meeting of the American Association for Cancer Research 2020; 2020 Apr 27-28 and Jun 22-24. Philadelphia (PA): AACR; Cancer Res 2020;80(16 Suppl):Abstract nr 4611.

Published
2020

26. Genome-Wide RNAi Screen Identifies PMPCB as a Therapeutic Vulnerability in EpCAM+ Hepatocellular Carcinoma

Author

Takai, Atsushi, primary, Dang, Hien, additional, Oishi, Naoki, additional, Khatib, Subreen, additional, Martin, Sean P., additional, Dominguez, Dana A., additional, Luo, Ji, additional, Bagni, Rachel, additional, Wu, Xiaolin, additional, Powell, Katie, additional, Ye, Qing-Hai, additional, Jia, Hu-Liang, additional, Qin, Lun-Xiu, additional, Chen, Jinqiu, additional, Mitchell, Gary A., additional, Luo, Xiaoling, additional, Thorgeirsson, Snorri S., additional, and Wang, Xin Wei, additional

Published
2019
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27. The NCI Transcriptional Pharmacodynamics Workbench: A Tool to Examine Dynamic Expression Profiling of Therapeutic Response in the NCI-60 Cell Line Panel

Author

Monks, Anne, primary, Zhao, Yingdong, additional, Hose, Curtis, additional, Hamed, Hossein, additional, Krushkal, Julia, additional, Fang, Jianwen, additional, Sonkin, Dmitriy, additional, Palmisano, Alida, additional, Polley, Eric C., additional, Fogli, Laura K., additional, Konaté, Mariam M., additional, Miller, Sarah B., additional, Simpson, Melanie A., additional, Voth, Andrea Regier, additional, Li, Ming-Chung, additional, Harris, Erik, additional, Wu, Xiaolin, additional, Connelly, John W., additional, Rapisarda, Annamaria, additional, Teicher, Beverly A., additional, Simon, Richard, additional, and Doroshow, James H., additional

Published
2018
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28. Abstract 4873: IKKα bridges central tolerance to innate immunity and inflammation

Author

Zhu, Feng, primary, Chen, Zhisong, additional, Willette-Brown, Jami, additional, Lomada, Dakshayani, additional, Davis, Sean R., additional, Back, Timothy, additional, Yoshimura, Teizo, additional, Sun, Zhonghe, additional, Wu, Xiaolin, additional, Wiltrout, Robert, additional, Richie, Ellen, additional, Siebenlist, Ulrich, additional, Trichieri, Giorgio, additional, and Hu, Yinling, additional

Published
2014
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30. Abstract 1083: The pivotal role of IKKalpha in the development of spontaneous lung squamous cell carcinomas.

Author

Xiao, Zuoxiang, primary, Jiang, Qun, additional, Willette-Brown, Jami, additional, Zhu, Feng, additional, Xi, Sichuan, additional, Burkett, Sandra, additional, Lin, Fanching, additional, Back, Timothy, additional, Datla, Mahesh, additional, Sun, Zhonghe, additional, Goldszmid, Romina, additional, Wu, Xiaolin, additional, Schrump, David, additional, Young, Howard, additional, Trinchieri, Georgio, additional, Wiltrout, Robert, additional, and Hu, Yinling, additional

Published
2013
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32. Relationship ofEGFRMutations, Expression, Amplification, and Polymorphisms to Epidermal Growth Factor Receptor Inhibitors in the NCI60 Cell Lines

Author

Liu, Wanqing, primary, Wu, Xiaolin, additional, Zhang, Wei, additional, Montenegro, Raquel C., additional, Fackenthal, Donna Lee, additional, Spitz, Jared A., additional, Huff, Lyn Mickley, additional, Innocenti, Federico, additional, Das, Soma, additional, Cook,, Edwin H., additional, Cox, Nancy J., additional, Bates, Susan E., additional, and Ratain, Mark J., additional

Published
2007
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34. Accelerated Preclinical Testing Using Transplanted Tumors from Genetically Engineered Mouse Breast Cancer Models

Author

Varticovski, Lyuba, primary, Hollingshead, Melinda G., additional, Robles, Ana I., additional, Wu, Xiaolin, additional, Cherry, James, additional, Munroe, David J., additional, Lukes, Luanne, additional, Anver, Miriam R., additional, Carter, John P., additional, Borgel, Suzanne D., additional, Stotler, Howard, additional, Bonomi, Carrie A., additional, Nunez, Nomelí P., additional, Hursting, Stephen D., additional, Qiao, Wenhui, additional, Deng, Chuxia X., additional, Green, Jeff E., additional, Hunter, Kent W., additional, Merlino, Glenn, additional, Steeg, Patricia S., additional, Wakefield, Lalage M., additional, and Barrett, J. Carl, additional

Published
2007
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