48 results on '"Tyrer, Jonathan P"'
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2. Supplementary Figure 1 from Folate Intake and Ovarian Cancer Risk among Women with Endometriosis: A Case–Control Study from the Ovarian Cancer Association Consortium
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Gersekowski, Kate, primary, Ibiebele, Torukiri I, primary, Doherty, Jennifer A., primary, Harris, Holly R., primary, Goodman, Marc T., primary, Terry, Kathryn L., primary, Wu, Anna H., primary, Bandera, Elisa V., primary, Qin, Bo, primary, Ong, Jue-Sheng, primary, Tyrer, Jonathan P., primary, Dixon-Suen, Suzanne C., primary, Modugno, Francesmary, primary, Risch, Harvey A, primary, and Webb, Penelope M., primary
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- 2023
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3. Table 3 from Folate Intake and Ovarian Cancer Risk among Women with Endometriosis: A Case–Control Study from the Ovarian Cancer Association Consortium
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Gersekowski, Kate, primary, Ibiebele, Torukiri I, primary, Doherty, Jennifer A., primary, Harris, Holly R., primary, Goodman, Marc T., primary, Terry, Kathryn L., primary, Wu, Anna H., primary, Bandera, Elisa V., primary, Qin, Bo, primary, Ong, Jue-Sheng, primary, Tyrer, Jonathan P., primary, Dixon-Suen, Suzanne C., primary, Modugno, Francesmary, primary, Risch, Harvey A, primary, and Webb, Penelope M., primary
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- 2023
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4. Data from Folate Intake and Ovarian Cancer Risk among Women with Endometriosis: A Case–Control Study from the Ovarian Cancer Association Consortium
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Gersekowski, Kate, primary, Ibiebele, Torukiri I, primary, Doherty, Jennifer A., primary, Harris, Holly R., primary, Goodman, Marc T., primary, Terry, Kathryn L., primary, Wu, Anna H., primary, Bandera, Elisa V., primary, Qin, Bo, primary, Ong, Jue-Sheng, primary, Tyrer, Jonathan P., primary, Dixon-Suen, Suzanne C., primary, Modugno, Francesmary, primary, Risch, Harvey A, primary, and Webb, Penelope M., primary
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- 2023
- Full Text
- View/download PDF
5. Supplementary Table 2 from Folate Intake and Ovarian Cancer Risk among Women with Endometriosis: A Case–Control Study from the Ovarian Cancer Association Consortium
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Gersekowski, Kate, primary, Ibiebele, Torukiri I, primary, Doherty, Jennifer A., primary, Harris, Holly R., primary, Goodman, Marc T., primary, Terry, Kathryn L., primary, Wu, Anna H., primary, Bandera, Elisa V., primary, Qin, Bo, primary, Ong, Jue-Sheng, primary, Tyrer, Jonathan P., primary, Dixon-Suen, Suzanne C., primary, Modugno, Francesmary, primary, Risch, Harvey A, primary, and Webb, Penelope M., primary
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- 2023
- Full Text
- View/download PDF
6. Supplementary Table 5 from Folate Intake and Ovarian Cancer Risk among Women with Endometriosis: A Case–Control Study from the Ovarian Cancer Association Consortium
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Gersekowski, Kate, primary, Ibiebele, Torukiri I, primary, Doherty, Jennifer A., primary, Harris, Holly R., primary, Goodman, Marc T., primary, Terry, Kathryn L., primary, Wu, Anna H., primary, Bandera, Elisa V., primary, Qin, Bo, primary, Ong, Jue-Sheng, primary, Tyrer, Jonathan P., primary, Dixon-Suen, Suzanne C., primary, Modugno, Francesmary, primary, Risch, Harvey A, primary, and Webb, Penelope M., primary
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- 2023
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- View/download PDF
7. Supplementary Figure 3 from Folate Intake and Ovarian Cancer Risk among Women with Endometriosis: A Case–Control Study from the Ovarian Cancer Association Consortium
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Gersekowski, Kate, primary, Ibiebele, Torukiri I, primary, Doherty, Jennifer A., primary, Harris, Holly R., primary, Goodman, Marc T., primary, Terry, Kathryn L., primary, Wu, Anna H., primary, Bandera, Elisa V., primary, Qin, Bo, primary, Ong, Jue-Sheng, primary, Tyrer, Jonathan P., primary, Dixon-Suen, Suzanne C., primary, Modugno, Francesmary, primary, Risch, Harvey A, primary, and Webb, Penelope M., primary
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- 2023
- Full Text
- View/download PDF
8. Supplementary Table 1 from Folate Intake and Ovarian Cancer Risk among Women with Endometriosis: A Case–Control Study from the Ovarian Cancer Association Consortium
- Author
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Gersekowski, Kate, primary, Ibiebele, Torukiri I, primary, Doherty, Jennifer A., primary, Harris, Holly R., primary, Goodman, Marc T., primary, Terry, Kathryn L., primary, Wu, Anna H., primary, Bandera, Elisa V., primary, Qin, Bo, primary, Ong, Jue-Sheng, primary, Tyrer, Jonathan P., primary, Dixon-Suen, Suzanne C., primary, Modugno, Francesmary, primary, Risch, Harvey A, primary, and Webb, Penelope M., primary
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- 2023
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- View/download PDF
9. Table 2 from Folate Intake and Ovarian Cancer Risk among Women with Endometriosis: A Case–Control Study from the Ovarian Cancer Association Consortium
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Gersekowski, Kate, primary, Ibiebele, Torukiri I, primary, Doherty, Jennifer A., primary, Harris, Holly R., primary, Goodman, Marc T., primary, Terry, Kathryn L., primary, Wu, Anna H., primary, Bandera, Elisa V., primary, Qin, Bo, primary, Ong, Jue-Sheng, primary, Tyrer, Jonathan P., primary, Dixon-Suen, Suzanne C., primary, Modugno, Francesmary, primary, Risch, Harvey A, primary, and Webb, Penelope M., primary
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- 2023
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10. Supplementary Table 3 from Folate Intake and Ovarian Cancer Risk among Women with Endometriosis: A Case–Control Study from the Ovarian Cancer Association Consortium
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Gersekowski, Kate, primary, Ibiebele, Torukiri I, primary, Doherty, Jennifer A., primary, Harris, Holly R., primary, Goodman, Marc T., primary, Terry, Kathryn L., primary, Wu, Anna H., primary, Bandera, Elisa V., primary, Qin, Bo, primary, Ong, Jue-Sheng, primary, Tyrer, Jonathan P., primary, Dixon-Suen, Suzanne C., primary, Modugno, Francesmary, primary, Risch, Harvey A, primary, and Webb, Penelope M., primary
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- 2023
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11. Supplementary Table 4 from Folate Intake and Ovarian Cancer Risk among Women with Endometriosis: A Case–Control Study from the Ovarian Cancer Association Consortium
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Gersekowski, Kate, primary, Ibiebele, Torukiri I, primary, Doherty, Jennifer A., primary, Harris, Holly R., primary, Goodman, Marc T., primary, Terry, Kathryn L., primary, Wu, Anna H., primary, Bandera, Elisa V., primary, Qin, Bo, primary, Ong, Jue-Sheng, primary, Tyrer, Jonathan P., primary, Dixon-Suen, Suzanne C., primary, Modugno, Francesmary, primary, Risch, Harvey A, primary, and Webb, Penelope M., primary
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- 2023
- Full Text
- View/download PDF
12. Table 1 from Folate Intake and Ovarian Cancer Risk among Women with Endometriosis: A Case–Control Study from the Ovarian Cancer Association Consortium
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Gersekowski, Kate, primary, Ibiebele, Torukiri I, primary, Doherty, Jennifer A., primary, Harris, Holly R., primary, Goodman, Marc T., primary, Terry, Kathryn L., primary, Wu, Anna H., primary, Bandera, Elisa V., primary, Qin, Bo, primary, Ong, Jue-Sheng, primary, Tyrer, Jonathan P., primary, Dixon-Suen, Suzanne C., primary, Modugno, Francesmary, primary, Risch, Harvey A, primary, and Webb, Penelope M., primary
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- 2023
- Full Text
- View/download PDF
13. Folate intake and ovarian cancer risk among women with endometriosis: a case-control study from the Ovarian Cancer Association Consortium
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Gersekowski, Kate, primary, Ibiebele, Torukiri I., additional, Doherty, Jennifer A., additional, Harris, Holly R., additional, Goodman, Marc T., additional, Terry, Kathryn L., additional, Wu, Anna H., additional, Bandera, Elisa V., additional, Qin, Bo, additional, Ong, Jue-Sheng, additional, Tyrer, Jonathan P., additional, Dixon-Suen, Suzanne C., additional, Modugno, Francesmary, additional, Risch, Harvey A., additional, and Webb, Penelope M., additional
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- 2023
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14. Supplementary Table 1 from Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations
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Fehringer, Gordon, primary, Kraft, Peter, primary, Pharoah, Paul D., primary, Eeles, Rosalind A., primary, Chatterjee, Nilanjan, primary, Schumacher, Fredrick R., primary, Schildkraut, Joellen M., primary, Lindström, Sara, primary, Brennan, Paul, primary, Bickeböller, Heike, primary, Houlston, Richard S., primary, Landi, Maria Teresa, primary, Caporaso, Neil, primary, Risch, Angela, primary, Amin Al Olama, Ali, primary, Berndt, Sonja I., primary, Giovannucci, Edward L., primary, Grönberg, Henrik, primary, Kote-Jarai, Zsofia, primary, Ma, Jing, primary, Muir, Kenneth, primary, Stampfer, Meir J., primary, Stevens, Victoria L., primary, Wiklund, Fredrik, primary, Willett, Walter C., primary, Goode, Ellen L., primary, Permuth, Jennifer B., primary, Risch, Harvey A., primary, Reid, Brett M., primary, Bezieau, Stephane, primary, Brenner, Hermann, primary, Chan, Andrew T., primary, Chang-Claude, Jenny, primary, Hudson, Thomas J., primary, Kocarnik, Jonathan K., primary, Newcomb, Polly A., primary, Schoen, Robert E., primary, Slattery, Martha L., primary, White, Emily, primary, Adank, Muriel A., primary, Ahsan, Habibul, primary, Aittomäki, Kristiina, primary, Baglietto, Laura, primary, Blomquist, Carl, primary, Canzian, Federico, primary, Czene, Kamila, primary, dos-Santos-Silva, Isabel, primary, Eliassen, A. Heather, primary, Figueroa, Jonine D., primary, Flesch-Janys, Dieter, primary, Fletcher, Olivia, primary, Garcia-Closas, Montserrat, primary, Gaudet, Mia M., primary, Johnson, Nichola, primary, Hall, Per, primary, Hazra, Aditi, primary, Hein, Rebecca, primary, Hofman, Albert, primary, Hopper, John L., primary, Irwanto, Astrid, primary, Johansson, Mattias, primary, Kaaks, Rudolf, primary, Kibriya, Muhammad G., primary, Lichtner, Peter, primary, Liu, Jianjun, primary, Lund, Eiliv, primary, Makalic, Enes, primary, Meindl, Alfons, primary, Müller-Myhsok, Bertram, primary, Muranen, Taru A., primary, Nevanlinna, Heli, primary, Peeters, Petra H., primary, Peto, Julian, primary, Prentice, Ross L., primary, Rahman, Nazneen, primary, Sanchez, Maria Jose, primary, Schmidt, Daniel F., primary, Schmutzler, Rita K., primary, Southey, Melissa C., primary, Tamimi, Rulla, primary, Travis, Ruth C., primary, Turnbull, Clare, primary, Uitterlinden, Andre G., primary, Wang, Zhaoming, primary, Whittemore, Alice S., primary, Yang, Xiaohong R., primary, Zheng, Wei, primary, Buchanan, Daniel D., primary, Casey, Graham, primary, Conti, David V., primary, Edlund, Christopher K., primary, Gallinger, Steven, primary, Haile, Robert W., primary, Jenkins, Mark, primary, Le Marchand, Loïc, primary, Li, Li, primary, Lindor, Noralene M., primary, Schmit, Stephanie L., primary, Thibodeau, Stephen N., primary, Woods, Michael O., primary, Rafnar, Thorunn, primary, Gudmundsson, Julius, primary, Stacey, Simon N., primary, Stefansson, Kari, primary, Sulem, Patrick, primary, Chen, Y. Ann, primary, Tyrer, Jonathan P., primary, Christiani, David C., primary, Wei, Yongyue, primary, Shen, Hongbing, primary, Hu, Zhibin, primary, Shu, Xiao-Ou, primary, Shiraishi, Kouya, primary, Takahashi, Atsushi, primary, Bossé, Yohan, primary, Obeidat, Ma'en, primary, Nickle, David, primary, Timens, Wim, primary, Freedman, Matthew L., primary, Li, Qiyuan, primary, Seminara, Daniela, primary, Chanock, Stephen J., primary, Gong, Jian, primary, Peters, Ulrike, primary, Gruber, Stephen B., primary, Amos, Christopher I., primary, Sellers, Thomas A., primary, Easton, Douglas F., primary, Hunter, David J., primary, Haiman, Christopher A., primary, Henderson, Brian E., primary, and Hung, Rayjean J., primary
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- 2023
- Full Text
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15. Figure S6A from Investigation of Exomic Variants Associated with Overall Survival in Ovarian Cancer
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Winham, Stacey J., primary, Pirie, Ailith, primary, Chen, Yian Ann, primary, Larson, Melissa C., primary, Fogarty, Zachary C., primary, Earp, Madalene A., primary, Anton-Culver, Hoda, primary, Bandera, Elisa V., primary, Cramer, Daniel, primary, Doherty, Jennifer A., primary, Goodman, Marc T., primary, Gronwald, Jacek, primary, Karlan, Beth Y., primary, Kjaer, Susanne K., primary, Levine, Douglas A., primary, Menon, Usha, primary, Ness, Roberta B., primary, Pearce, Celeste L., primary, Pejovic, Tanja, primary, Rossing, Mary Anne, primary, Wentzensen, Nicolas, primary, Bean, Yukie T., primary, Bisogna, Maria, primary, Brinton, Louise A., primary, Carney, Michael E., primary, Cunningham, Julie M., primary, Cybulski, Cezary, primary, deFazio, Anna, primary, Dicks, Ed M., primary, Edwards, Robert P., primary, Gayther, Simon A., primary, Gentry-Maharaj, Aleksandra, primary, Gore, Martin, primary, Iversen, Edwin S., primary, Jensen, Allan, primary, Johnatty, Sharon E., primary, Lester, Jenny, primary, Lin, Hui-Yi, primary, Lissowska, Jolanta, primary, Lubinski, Jan, primary, Menkiszak, Janusz, primary, Modugno, Francesmary, primary, Moysich, Kirsten B., primary, Orlow, Irene, primary, Pike, Malcolm C., primary, Ramus, Susan J., primary, Song, Honglin, primary, Terry, Kathryn L., primary, Thompson, Pamela J., primary, Tyrer, Jonathan P., primary, van den Berg, David J., primary, Vierkant, Robert A., primary, Vitonis, Allison F., primary, Walsh, Christine, primary, Wilkens, Lynne R., primary, Wu, Anna H., primary, Yang, Hannah, primary, Ziogas, Argyrios, primary, Berchuck, Andrew, primary, Schildkraut, Joellen M., primary, Permuth-Wey, Jennifer, primary, Phelan, Catherine M., primary, Pharoah, Paul D.P., primary, Fridley, Brooke L., primary, Sellers, Thomas A., primary, and Goode, Ellen L., primary
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- 2023
- Full Text
- View/download PDF
16. Data from Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations
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Fehringer, Gordon, primary, Kraft, Peter, primary, Pharoah, Paul D., primary, Eeles, Rosalind A., primary, Chatterjee, Nilanjan, primary, Schumacher, Fredrick R., primary, Schildkraut, Joellen M., primary, Lindström, Sara, primary, Brennan, Paul, primary, Bickeböller, Heike, primary, Houlston, Richard S., primary, Landi, Maria Teresa, primary, Caporaso, Neil, primary, Risch, Angela, primary, Amin Al Olama, Ali, primary, Berndt, Sonja I., primary, Giovannucci, Edward L., primary, Grönberg, Henrik, primary, Kote-Jarai, Zsofia, primary, Ma, Jing, primary, Muir, Kenneth, primary, Stampfer, Meir J., primary, Stevens, Victoria L., primary, Wiklund, Fredrik, primary, Willett, Walter C., primary, Goode, Ellen L., primary, Permuth, Jennifer B., primary, Risch, Harvey A., primary, Reid, Brett M., primary, Bezieau, Stephane, primary, Brenner, Hermann, primary, Chan, Andrew T., primary, Chang-Claude, Jenny, primary, Hudson, Thomas J., primary, Kocarnik, Jonathan K., primary, Newcomb, Polly A., primary, Schoen, Robert E., primary, Slattery, Martha L., primary, White, Emily, primary, Adank, Muriel A., primary, Ahsan, Habibul, primary, Aittomäki, Kristiina, primary, Baglietto, Laura, primary, Blomquist, Carl, primary, Canzian, Federico, primary, Czene, Kamila, primary, dos-Santos-Silva, Isabel, primary, Eliassen, A. Heather, primary, Figueroa, Jonine D., primary, Flesch-Janys, Dieter, primary, Fletcher, Olivia, primary, Garcia-Closas, Montserrat, primary, Gaudet, Mia M., primary, Johnson, Nichola, primary, Hall, Per, primary, Hazra, Aditi, primary, Hein, Rebecca, primary, Hofman, Albert, primary, Hopper, John L., primary, Irwanto, Astrid, primary, Johansson, Mattias, primary, Kaaks, Rudolf, primary, Kibriya, Muhammad G., primary, Lichtner, Peter, primary, Liu, Jianjun, primary, Lund, Eiliv, primary, Makalic, Enes, primary, Meindl, Alfons, primary, Müller-Myhsok, Bertram, primary, Muranen, Taru A., primary, Nevanlinna, Heli, primary, Peeters, Petra H., primary, Peto, Julian, primary, Prentice, Ross L., primary, Rahman, Nazneen, primary, Sanchez, Maria Jose, primary, Schmidt, Daniel F., primary, Schmutzler, Rita K., primary, Southey, Melissa C., primary, Tamimi, Rulla, primary, Travis, Ruth C., primary, Turnbull, Clare, primary, Uitterlinden, Andre G., primary, Wang, Zhaoming, primary, Whittemore, Alice S., primary, Yang, Xiaohong R., primary, Zheng, Wei, primary, Buchanan, Daniel D., primary, Casey, Graham, primary, Conti, David V., primary, Edlund, Christopher K., primary, Gallinger, Steven, primary, Haile, Robert W., primary, Jenkins, Mark, primary, Le Marchand, Loïc, primary, Li, Li, primary, Lindor, Noralene M., primary, Schmit, Stephanie L., primary, Thibodeau, Stephen N., primary, Woods, Michael O., primary, Rafnar, Thorunn, primary, Gudmundsson, Julius, primary, Stacey, Simon N., primary, Stefansson, Kari, primary, Sulem, Patrick, primary, Chen, Y. Ann, primary, Tyrer, Jonathan P., primary, Christiani, David C., primary, Wei, Yongyue, primary, Shen, Hongbing, primary, Hu, Zhibin, primary, Shu, Xiao-Ou, primary, Shiraishi, Kouya, primary, Takahashi, Atsushi, primary, Bossé, Yohan, primary, Obeidat, Ma'en, primary, Nickle, David, primary, Timens, Wim, primary, Freedman, Matthew L., primary, Li, Qiyuan, primary, Seminara, Daniela, primary, Chanock, Stephen J., primary, Gong, Jian, primary, Peters, Ulrike, primary, Gruber, Stephen B., primary, Amos, Christopher I., primary, Sellers, Thomas A., primary, Easton, Douglas F., primary, Hunter, David J., primary, Haiman, Christopher A., primary, Henderson, Brian E., primary, and Hung, Rayjean J., primary
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- 2023
- Full Text
- View/download PDF
17. Supplementary Table 2 and Supplemental Figures from Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations
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Fehringer, Gordon, primary, Kraft, Peter, primary, Pharoah, Paul D., primary, Eeles, Rosalind A., primary, Chatterjee, Nilanjan, primary, Schumacher, Fredrick R., primary, Schildkraut, Joellen M., primary, Lindström, Sara, primary, Brennan, Paul, primary, Bickeböller, Heike, primary, Houlston, Richard S., primary, Landi, Maria Teresa, primary, Caporaso, Neil, primary, Risch, Angela, primary, Amin Al Olama, Ali, primary, Berndt, Sonja I., primary, Giovannucci, Edward L., primary, Grönberg, Henrik, primary, Kote-Jarai, Zsofia, primary, Ma, Jing, primary, Muir, Kenneth, primary, Stampfer, Meir J., primary, Stevens, Victoria L., primary, Wiklund, Fredrik, primary, Willett, Walter C., primary, Goode, Ellen L., primary, Permuth, Jennifer B., primary, Risch, Harvey A., primary, Reid, Brett M., primary, Bezieau, Stephane, primary, Brenner, Hermann, primary, Chan, Andrew T., primary, Chang-Claude, Jenny, primary, Hudson, Thomas J., primary, Kocarnik, Jonathan K., primary, Newcomb, Polly A., primary, Schoen, Robert E., primary, Slattery, Martha L., primary, White, Emily, primary, Adank, Muriel A., primary, Ahsan, Habibul, primary, Aittomäki, Kristiina, primary, Baglietto, Laura, primary, Blomquist, Carl, primary, Canzian, Federico, primary, Czene, Kamila, primary, dos-Santos-Silva, Isabel, primary, Eliassen, A. Heather, primary, Figueroa, Jonine D., primary, Flesch-Janys, Dieter, primary, Fletcher, Olivia, primary, Garcia-Closas, Montserrat, primary, Gaudet, Mia M., primary, Johnson, Nichola, primary, Hall, Per, primary, Hazra, Aditi, primary, Hein, Rebecca, primary, Hofman, Albert, primary, Hopper, John L., primary, Irwanto, Astrid, primary, Johansson, Mattias, primary, Kaaks, Rudolf, primary, Kibriya, Muhammad G., primary, Lichtner, Peter, primary, Liu, Jianjun, primary, Lund, Eiliv, primary, Makalic, Enes, primary, Meindl, Alfons, primary, Müller-Myhsok, Bertram, primary, Muranen, Taru A., primary, Nevanlinna, Heli, primary, Peeters, Petra H., primary, Peto, Julian, primary, Prentice, Ross L., primary, Rahman, Nazneen, primary, Sanchez, Maria Jose, primary, Schmidt, Daniel F., primary, Schmutzler, Rita K., primary, Southey, Melissa C., primary, Tamimi, Rulla, primary, Travis, Ruth C., primary, Turnbull, Clare, primary, Uitterlinden, Andre G., primary, Wang, Zhaoming, primary, Whittemore, Alice S., primary, Yang, Xiaohong R., primary, Zheng, Wei, primary, Buchanan, Daniel D., primary, Casey, Graham, primary, Conti, David V., primary, Edlund, Christopher K., primary, Gallinger, Steven, primary, Haile, Robert W., primary, Jenkins, Mark, primary, Le Marchand, Loïc, primary, Li, Li, primary, Lindor, Noralene M., primary, Schmit, Stephanie L., primary, Thibodeau, Stephen N., primary, Woods, Michael O., primary, Rafnar, Thorunn, primary, Gudmundsson, Julius, primary, Stacey, Simon N., primary, Stefansson, Kari, primary, Sulem, Patrick, primary, Chen, Y. Ann, primary, Tyrer, Jonathan P., primary, Christiani, David C., primary, Wei, Yongyue, primary, Shen, Hongbing, primary, Hu, Zhibin, primary, Shu, Xiao-Ou, primary, Shiraishi, Kouya, primary, Takahashi, Atsushi, primary, Bossé, Yohan, primary, Obeidat, Ma'en, primary, Nickle, David, primary, Timens, Wim, primary, Freedman, Matthew L., primary, Li, Qiyuan, primary, Seminara, Daniela, primary, Chanock, Stephen J., primary, Gong, Jian, primary, Peters, Ulrike, primary, Gruber, Stephen B., primary, Amos, Christopher I., primary, Sellers, Thomas A., primary, Easton, Douglas F., primary, Hunter, David J., primary, Haiman, Christopher A., primary, Henderson, Brian E., primary, and Hung, Rayjean J., primary
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- 2023
- Full Text
- View/download PDF
18. Supplementary Table 5 from Functional Analysis and Fine Mapping of the 9p22.2 Ovarian Cancer Susceptibility Locus
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Buckley, Melissa A., primary, Woods, Nicholas T., primary, Tyrer, Jonathan P., primary, Mendoza-Fandiño, Gustavo, primary, Lawrenson, Kate, primary, Hazelett, Dennis J., primary, Najafabadi, Hamed S., primary, Gjyshi, Anxhela, primary, Carvalho, Renato S., primary, Lyra, Paulo C., primary, Coetzee, Simon G., primary, Shen, Howard C., primary, Yang, Ally W., primary, Earp, Madalene A., primary, Yoder, Sean J., primary, Risch, Harvey, primary, Chenevix-Trench, Georgia, primary, Ramus, Susan J., primary, Phelan, Catherine M., primary, Coetzee, Gerhard A., primary, Noushmehr, Houtan, primary, Hughes, Timothy R., primary, Sellers, Thomas A., primary, Goode, Ellen L., primary, Pharoah, Paul D., primary, Gayther, Simon A., primary, and Monteiro, Alvaro N.A., primary
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- 2023
- Full Text
- View/download PDF
19. Supplemental Figure Legends from Investigation of Exomic Variants Associated with Overall Survival in Ovarian Cancer
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Winham, Stacey J., primary, Pirie, Ailith, primary, Chen, Yian Ann, primary, Larson, Melissa C., primary, Fogarty, Zachary C., primary, Earp, Madalene A., primary, Anton-Culver, Hoda, primary, Bandera, Elisa V., primary, Cramer, Daniel, primary, Doherty, Jennifer A., primary, Goodman, Marc T., primary, Gronwald, Jacek, primary, Karlan, Beth Y., primary, Kjaer, Susanne K., primary, Levine, Douglas A., primary, Menon, Usha, primary, Ness, Roberta B., primary, Pearce, Celeste L., primary, Pejovic, Tanja, primary, Rossing, Mary Anne, primary, Wentzensen, Nicolas, primary, Bean, Yukie T., primary, Bisogna, Maria, primary, Brinton, Louise A., primary, Carney, Michael E., primary, Cunningham, Julie M., primary, Cybulski, Cezary, primary, deFazio, Anna, primary, Dicks, Ed M., primary, Edwards, Robert P., primary, Gayther, Simon A., primary, Gentry-Maharaj, Aleksandra, primary, Gore, Martin, primary, Iversen, Edwin S., primary, Jensen, Allan, primary, Johnatty, Sharon E., primary, Lester, Jenny, primary, Lin, Hui-Yi, primary, Lissowska, Jolanta, primary, Lubinski, Jan, primary, Menkiszak, Janusz, primary, Modugno, Francesmary, primary, Moysich, Kirsten B., primary, Orlow, Irene, primary, Pike, Malcolm C., primary, Ramus, Susan J., primary, Song, Honglin, primary, Terry, Kathryn L., primary, Thompson, Pamela J., primary, Tyrer, Jonathan P., primary, van den Berg, David J., primary, Vierkant, Robert A., primary, Vitonis, Allison F., primary, Walsh, Christine, primary, Wilkens, Lynne R., primary, Wu, Anna H., primary, Yang, Hannah, primary, Ziogas, Argyrios, primary, Berchuck, Andrew, primary, Schildkraut, Joellen M., primary, Permuth-Wey, Jennifer, primary, Phelan, Catherine M., primary, Pharoah, Paul D.P., primary, Fridley, Brooke L., primary, Sellers, Thomas A., primary, and Goode, Ellen L., primary
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- 2023
- Full Text
- View/download PDF
20. Supplementary Figures 1-4 and extended methods from Functional Analysis and Fine Mapping of the 9p22.2 Ovarian Cancer Susceptibility Locus
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Buckley, Melissa A., primary, Woods, Nicholas T., primary, Tyrer, Jonathan P., primary, Mendoza-Fandiño, Gustavo, primary, Lawrenson, Kate, primary, Hazelett, Dennis J., primary, Najafabadi, Hamed S., primary, Gjyshi, Anxhela, primary, Carvalho, Renato S., primary, Lyra, Paulo C., primary, Coetzee, Simon G., primary, Shen, Howard C., primary, Yang, Ally W., primary, Earp, Madalene A., primary, Yoder, Sean J., primary, Risch, Harvey, primary, Chenevix-Trench, Georgia, primary, Ramus, Susan J., primary, Phelan, Catherine M., primary, Coetzee, Gerhard A., primary, Noushmehr, Houtan, primary, Hughes, Timothy R., primary, Sellers, Thomas A., primary, Goode, Ellen L., primary, Pharoah, Paul D., primary, Gayther, Simon A., primary, and Monteiro, Alvaro N.A., primary
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- 2023
- Full Text
- View/download PDF
21. Supplemental Tables from Investigation of Exomic Variants Associated with Overall Survival in Ovarian Cancer
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Winham, Stacey J., primary, Pirie, Ailith, primary, Chen, Yian Ann, primary, Larson, Melissa C., primary, Fogarty, Zachary C., primary, Earp, Madalene A., primary, Anton-Culver, Hoda, primary, Bandera, Elisa V., primary, Cramer, Daniel, primary, Doherty, Jennifer A., primary, Goodman, Marc T., primary, Gronwald, Jacek, primary, Karlan, Beth Y., primary, Kjaer, Susanne K., primary, Levine, Douglas A., primary, Menon, Usha, primary, Ness, Roberta B., primary, Pearce, Celeste L., primary, Pejovic, Tanja, primary, Rossing, Mary Anne, primary, Wentzensen, Nicolas, primary, Bean, Yukie T., primary, Bisogna, Maria, primary, Brinton, Louise A., primary, Carney, Michael E., primary, Cunningham, Julie M., primary, Cybulski, Cezary, primary, deFazio, Anna, primary, Dicks, Ed M., primary, Edwards, Robert P., primary, Gayther, Simon A., primary, Gentry-Maharaj, Aleksandra, primary, Gore, Martin, primary, Iversen, Edwin S., primary, Jensen, Allan, primary, Johnatty, Sharon E., primary, Lester, Jenny, primary, Lin, Hui-Yi, primary, Lissowska, Jolanta, primary, Lubinski, Jan, primary, Menkiszak, Janusz, primary, Modugno, Francesmary, primary, Moysich, Kirsten B., primary, Orlow, Irene, primary, Pike, Malcolm C., primary, Ramus, Susan J., primary, Song, Honglin, primary, Terry, Kathryn L., primary, Thompson, Pamela J., primary, Tyrer, Jonathan P., primary, van den Berg, David J., primary, Vierkant, Robert A., primary, Vitonis, Allison F., primary, Walsh, Christine, primary, Wilkens, Lynne R., primary, Wu, Anna H., primary, Yang, Hannah, primary, Ziogas, Argyrios, primary, Berchuck, Andrew, primary, Schildkraut, Joellen M., primary, Permuth-Wey, Jennifer, primary, Phelan, Catherine M., primary, Pharoah, Paul D.P., primary, Fridley, Brooke L., primary, Sellers, Thomas A., primary, and Goode, Ellen L., primary
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22. Supplemental Figure 1 from Assessment of Multifactor Gene–Environment Interactions and Ovarian Cancer Risk: Candidate Genes, Obesity, and Hormone-Related Risk Factors
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Usset, Joseph L., primary, Raghavan, Rama, primary, Tyrer, Jonathan P., primary, McGuire, Valerie, primary, Sieh, Weiva, primary, Webb, Penelope, primary, Chang-Claude, Jenny, primary, Rudolph, Anja, primary, Anton-Culver, Hoda, primary, Berchuck, Andrew, primary, Brinton, Louise, primary, Cunningham, Julie M., primary, DeFazio, Anna, primary, Doherty, Jennifer A., primary, Edwards, Robert P., primary, Gayther, Simon A., primary, Gentry-Maharaj, Aleksandra, primary, Goodman, Marc T., primary, Høgdall, Estrid, primary, Jensen, Allan, primary, Johnatty, Sharon E., primary, Kiemeney, Lambertus A., primary, Kjaer, Susanne K., primary, Larson, Melissa C., primary, Lurie, Galina, primary, Massuger, Leon, primary, Menon, Usha, primary, Modugno, Francesmary, primary, Moysich, Kirsten B., primary, Ness, Roberta B., primary, Pike, Malcolm C., primary, Ramus, Susan J., primary, Rossing, Mary Anne, primary, Rothstein, Joseph, primary, Song, Honglin, primary, Thompson, Pamela J., primary, van den Berg, David J., primary, Vierkant, Robert A., primary, Wang-Gohrke, Shan, primary, Wentzensen, Nicolas, primary, Whittemore, Alice S., primary, Wilkens, Lynne R., primary, Wu, Anna H., primary, Yang, Hannah, primary, Pearce, Celeste Leigh, primary, Schildkraut, Joellen M., primary, Pharoah, Paul, primary, Goode, Ellen L., primary, and Fridley, Brooke L., primary
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23. Data from Investigation of Exomic Variants Associated with Overall Survival in Ovarian Cancer
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Winham, Stacey J., primary, Pirie, Ailith, primary, Chen, Yian Ann, primary, Larson, Melissa C., primary, Fogarty, Zachary C., primary, Earp, Madalene A., primary, Anton-Culver, Hoda, primary, Bandera, Elisa V., primary, Cramer, Daniel, primary, Doherty, Jennifer A., primary, Goodman, Marc T., primary, Gronwald, Jacek, primary, Karlan, Beth Y., primary, Kjaer, Susanne K., primary, Levine, Douglas A., primary, Menon, Usha, primary, Ness, Roberta B., primary, Pearce, Celeste L., primary, Pejovic, Tanja, primary, Rossing, Mary Anne, primary, Wentzensen, Nicolas, primary, Bean, Yukie T., primary, Bisogna, Maria, primary, Brinton, Louise A., primary, Carney, Michael E., primary, Cunningham, Julie M., primary, Cybulski, Cezary, primary, deFazio, Anna, primary, Dicks, Ed M., primary, Edwards, Robert P., primary, Gayther, Simon A., primary, Gentry-Maharaj, Aleksandra, primary, Gore, Martin, primary, Iversen, Edwin S., primary, Jensen, Allan, primary, Johnatty, Sharon E., primary, Lester, Jenny, primary, Lin, Hui-Yi, primary, Lissowska, Jolanta, primary, Lubinski, Jan, primary, Menkiszak, Janusz, primary, Modugno, Francesmary, primary, Moysich, Kirsten B., primary, Orlow, Irene, primary, Pike, Malcolm C., primary, Ramus, Susan J., primary, Song, Honglin, primary, Terry, Kathryn L., primary, Thompson, Pamela J., primary, Tyrer, Jonathan P., primary, van den Berg, David J., primary, Vierkant, Robert A., primary, Vitonis, Allison F., primary, Walsh, Christine, primary, Wilkens, Lynne R., primary, Wu, Anna H., primary, Yang, Hannah, primary, Ziogas, Argyrios, primary, Berchuck, Andrew, primary, Schildkraut, Joellen M., primary, Permuth-Wey, Jennifer, primary, Phelan, Catherine M., primary, Pharoah, Paul D.P., primary, Fridley, Brooke L., primary, Sellers, Thomas A., primary, and Goode, Ellen L., primary
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24. Supplementary Table 4. Association of 47 waist-hip ratio (WHR) SNPs with endometrial cancer risk from Genetic Risk Score Mendelian Randomization Shows that Obesity Measured as Body Mass Index, but not Waist:Hip Ratio, Is Causal for Endometrial Cancer
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Painter, Jodie N., primary, O'Mara, Tracy A., primary, Marquart, Louise, primary, Webb, Penelope M., primary, Attia, John, primary, Medland, Sarah E., primary, Cheng, Timothy, primary, Dennis, Joe, primary, Holliday, Elizabeth G., primary, McEvoy, Mark, primary, Scott, Rodney J., primary, Ahmed, Shahana, primary, Healey, Catherine S., primary, Shah, Mitul, primary, Gorman, Maggie, primary, Martin, Lynn, primary, Hodgson, Shirley V., primary, Beckmann, Matthias W., primary, Ekici, Arif B., primary, Fasching, Peter A., primary, Hein, Alexander, primary, Rübner, Matthias, primary, Czene, Kamila, primary, Darabi, Hatef, primary, Hall, Per, primary, Li, Jingmei, primary, Dörk, Thilo, primary, Dürst, Matthias, primary, Hillemanns, Peter, primary, Runnebaum, Ingo B., primary, Amant, Frederic, primary, Annibali, Daniela, primary, Depreeuw, Jeroen, primary, Lambrechts, Diether, primary, Neven, Patrick, primary, Cunningham, Julie M., primary, Dowdy, Sean C., primary, Goode, Ellen L., primary, Fridley, Brooke L., primary, Winham, Stacey J., primary, Njølstad, Tormund S., primary, Salvesen, Helga B., primary, Trovik, Jone, primary, Werner, Henrica M.J., primary, Ashton, Katie A., primary, Otton, Geoffrey, primary, Proietto, Anthony, primary, Mints, Miriam, primary, Tham, Emma, primary, Bolla, Manjeet K., primary, Michailidou, Kyriaki, primary, Wang, Qin, primary, Tyrer, Jonathan P., primary, Hopper, John L., primary, Peto, Julian, primary, Swerdlow, Anthony J., primary, Burwinkel, Barbara, primary, Brenner, Hermann, primary, Meindl, Alfons, primary, Brauch, Hiltrud, primary, Lindblom, Annika, primary, Chang-Claude, Jenny, primary, Couch, Fergus J., primary, Giles, Graham G., primary, Kristensen, Vessela N., primary, Cox, Angela, primary, Pharoah, Paul D.P., primary, Tomlinson, Ian, primary, Dunning, Alison M., primary, Easton, Douglas F., primary, Thompson, Deborah J., primary, and Spurdle, Amanda B., primary
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25. Supplementary Table 3: Association of 77 body mass index (BMI) SNPs with endometrial cancer risk and BMI in the endometrial cancer dataset from Genetic Risk Score Mendelian Randomization Shows that Obesity Measured as Body Mass Index, but not Waist:Hip Ratio, Is Causal for Endometrial Cancer
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Painter, Jodie N., primary, O'Mara, Tracy A., primary, Marquart, Louise, primary, Webb, Penelope M., primary, Attia, John, primary, Medland, Sarah E., primary, Cheng, Timothy, primary, Dennis, Joe, primary, Holliday, Elizabeth G., primary, McEvoy, Mark, primary, Scott, Rodney J., primary, Ahmed, Shahana, primary, Healey, Catherine S., primary, Shah, Mitul, primary, Gorman, Maggie, primary, Martin, Lynn, primary, Hodgson, Shirley V., primary, Beckmann, Matthias W., primary, Ekici, Arif B., primary, Fasching, Peter A., primary, Hein, Alexander, primary, Rübner, Matthias, primary, Czene, Kamila, primary, Darabi, Hatef, primary, Hall, Per, primary, Li, Jingmei, primary, Dörk, Thilo, primary, Dürst, Matthias, primary, Hillemanns, Peter, primary, Runnebaum, Ingo B., primary, Amant, Frederic, primary, Annibali, Daniela, primary, Depreeuw, Jeroen, primary, Lambrechts, Diether, primary, Neven, Patrick, primary, Cunningham, Julie M., primary, Dowdy, Sean C., primary, Goode, Ellen L., primary, Fridley, Brooke L., primary, Winham, Stacey J., primary, Njølstad, Tormund S., primary, Salvesen, Helga B., primary, Trovik, Jone, primary, Werner, Henrica M.J., primary, Ashton, Katie A., primary, Otton, Geoffrey, primary, Proietto, Anthony, primary, Mints, Miriam, primary, Tham, Emma, primary, Bolla, Manjeet K., primary, Michailidou, Kyriaki, primary, Wang, Qin, primary, Tyrer, Jonathan P., primary, Hopper, John L., primary, Peto, Julian, primary, Swerdlow, Anthony J., primary, Burwinkel, Barbara, primary, Brenner, Hermann, primary, Meindl, Alfons, primary, Brauch, Hiltrud, primary, Lindblom, Annika, primary, Chang-Claude, Jenny, primary, Couch, Fergus J., primary, Giles, Graham G., primary, Kristensen, Vessela N., primary, Cox, Angela, primary, Pharoah, Paul D.P., primary, Tomlinson, Ian, primary, Dunning, Alison M., primary, Easton, Douglas F., primary, Thompson, Deborah J., primary, and Spurdle, Amanda B., primary
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26. Data from Network-Based Integration of GWAS and Gene Expression Identifies a HOX-Centric Network Associated with Serous Ovarian Cancer Risk
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Kar, Siddhartha P., primary, Tyrer, Jonathan P., primary, Li, Qiyuan, primary, Lawrenson, Kate, primary, Aben, Katja K.H., primary, Anton-Culver, Hoda, primary, Antonenkova, Natalia, primary, Chenevix-Trench, Georgia, primary, Baker, Helen, primary, Bandera, Elisa V., primary, Bean, Yukie T., primary, Beckmann, Matthias W., primary, Berchuck, Andrew, primary, Bisogna, Maria, primary, Bjørge, Line, primary, Bogdanova, Natalia, primary, Brinton, Louise, primary, Brooks-Wilson, Angela, primary, Butzow, Ralf, primary, Campbell, Ian, primary, Carty, Karen, primary, Chang-Claude, Jenny, primary, Chen, Yian Ann, primary, Chen, Zhihua, primary, Cook, Linda S., primary, Cramer, Daniel, primary, Cunningham, Julie M., primary, Cybulski, Cezary, primary, Dansonka-Mieszkowska, Agnieszka, primary, Dennis, Joe, primary, Dicks, Ed, primary, Doherty, Jennifer A., primary, Dörk, Thilo, primary, du Bois, Andreas, primary, Dürst, Matthias, primary, Eccles, Diana, primary, Easton, Douglas F., primary, Edwards, Robert P., primary, Ekici, Arif B., primary, Fasching, Peter A., primary, Fridley, Brooke L., primary, Gao, Yu-Tang, primary, Gentry-Maharaj, Aleksandra, primary, Giles, Graham G., primary, Glasspool, Rosalind, primary, Goode, Ellen L., primary, Goodman, Marc T., primary, Grownwald, Jacek, primary, Harrington, Patricia, primary, Harter, Philipp, primary, Hein, Alexander, primary, Heitz, Florian, primary, Hildebrandt, Michelle A.T., primary, Hillemanns, Peter, primary, Hogdall, Estrid, primary, Hogdall, Claus K., primary, Hosono, Satoyo, primary, Iversen, Edwin S., primary, Jakubowska, Anna, primary, Paul, James, primary, Jensen, Allan, primary, Ji, Bu-Tian, primary, Karlan, Beth Y., primary, Kjaer, Susanne K., primary, Kelemen, Linda E., primary, Kellar, Melissa, primary, Kelley, Joseph, primary, Kiemeney, Lambertus A., primary, Krakstad, Camilla, primary, Kupryjanczyk, Jolanta, primary, Lambrechts, Diether, primary, Lambrechts, Sandrina, primary, Le, Nhu D., primary, Lee, Alice W., primary, Lele, Shashi, primary, Leminen, Arto, primary, Lester, Jenny, primary, Levine, Douglas A., primary, Liang, Dong, primary, Lissowska, Jolanta, primary, Lu, Karen, primary, Lubinski, Jan, primary, Lundvall, Lene, primary, Massuger, Leon, primary, Matsuo, Keitaro, primary, McGuire, Valerie, primary, McLaughlin, John R., primary, McNeish, Iain A., primary, Menon, Usha, primary, Modugno, Francesmary, primary, Moysich, Kirsten B., primary, Narod, Steven A., primary, Nedergaard, Lotte, primary, Ness, Roberta B., primary, Nevanlinna, Heli, primary, Odunsi, Kunle, primary, Olson, Sara H., primary, Orlow, Irene, primary, Orsulic, Sandra, primary, Weber, Rachel Palmieri, primary, Pearce, Celeste Leigh, primary, Pejovic, Tanja, primary, Pelttari, Liisa M., primary, Permuth-Wey, Jennifer, primary, Phelan, Catherine M., primary, Pike, Malcolm C., primary, Poole, Elizabeth M., primary, Ramus, Susan J., primary, Risch, Harvey A., primary, Rosen, Barry, primary, Rossing, Mary Anne, primary, Rothstein, Joseph H., primary, Rudolph, Anja, primary, Runnebaum, Ingo B., primary, Rzepecka, Iwona K., primary, Salvesen, Helga B., primary, Schildkraut, Joellen M., primary, Schwaab, Ira, primary, Shu, Xiao-Ou, primary, Shvetsov, Yurii B., primary, Siddiqui, Nadeem, primary, Sieh, Weiva, primary, Song, Honglin, primary, Southey, Melissa C., primary, Sucheston-Campbell, Lara E., primary, Tangen, Ingvild L., primary, Teo, Soo-Hwang, primary, Terry, Kathryn L., primary, Thompson, Pamela J., primary, Timorek, Agnieszka, primary, Tsai, Ya-Yu, primary, Tworoger, Shelley S., primary, van Altena, Anne M., primary, Van Nieuwenhuysen, Els, primary, Vergote, Ignace, primary, Vierkant, Robert A., primary, Wang-Gohrke, Shan, primary, Walsh, Christine, primary, Wentzensen, Nicolas, primary, Whittemore, Alice S., primary, Wicklund, Kristine G., primary, Wilkens, Lynne R., primary, Woo, Yin-Ling, primary, Wu, Xifeng, primary, Wu, Anna, primary, Yang, Hannah, primary, Zheng, Wei, primary, Ziogas, Argyrios, primary, Sellers, Thomas A., primary, Monteiro, Alvaro N.A., primary, Freedman, Matthew L., primary, Gayther, Simon A., primary, and Pharoah, Paul D.P., primary
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27. Supplemental Table 1. Details of cases and controls included in the endometrial cancer analyses from Genetic Risk Score Mendelian Randomization Shows that Obesity Measured as Body Mass Index, but not Waist:Hip Ratio, Is Causal for Endometrial Cancer
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Painter, Jodie N., primary, O'Mara, Tracy A., primary, Marquart, Louise, primary, Webb, Penelope M., primary, Attia, John, primary, Medland, Sarah E., primary, Cheng, Timothy, primary, Dennis, Joe, primary, Holliday, Elizabeth G., primary, McEvoy, Mark, primary, Scott, Rodney J., primary, Ahmed, Shahana, primary, Healey, Catherine S., primary, Shah, Mitul, primary, Gorman, Maggie, primary, Martin, Lynn, primary, Hodgson, Shirley V., primary, Beckmann, Matthias W., primary, Ekici, Arif B., primary, Fasching, Peter A., primary, Hein, Alexander, primary, Rübner, Matthias, primary, Czene, Kamila, primary, Darabi, Hatef, primary, Hall, Per, primary, Li, Jingmei, primary, Dörk, Thilo, primary, Dürst, Matthias, primary, Hillemanns, Peter, primary, Runnebaum, Ingo B., primary, Amant, Frederic, primary, Annibali, Daniela, primary, Depreeuw, Jeroen, primary, Lambrechts, Diether, primary, Neven, Patrick, primary, Cunningham, Julie M., primary, Dowdy, Sean C., primary, Goode, Ellen L., primary, Fridley, Brooke L., primary, Winham, Stacey J., primary, Njølstad, Tormund S., primary, Salvesen, Helga B., primary, Trovik, Jone, primary, Werner, Henrica M.J., primary, Ashton, Katie A., primary, Otton, Geoffrey, primary, Proietto, Anthony, primary, Mints, Miriam, primary, Tham, Emma, primary, Bolla, Manjeet K., primary, Michailidou, Kyriaki, primary, Wang, Qin, primary, Tyrer, Jonathan P., primary, Hopper, John L., primary, Peto, Julian, primary, Swerdlow, Anthony J., primary, Burwinkel, Barbara, primary, Brenner, Hermann, primary, Meindl, Alfons, primary, Brauch, Hiltrud, primary, Lindblom, Annika, primary, Chang-Claude, Jenny, primary, Couch, Fergus J., primary, Giles, Graham G., primary, Kristensen, Vessela N., primary, Cox, Angela, primary, Pharoah, Paul D.P., primary, Tomlinson, Ian, primary, Dunning, Alison M., primary, Easton, Douglas F., primary, Thompson, Deborah J., primary, and Spurdle, Amanda B., primary
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28. Supplementary Table 3 from Functional Analysis and Fine Mapping of the 9p22.2 Ovarian Cancer Susceptibility Locus
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Buckley, Melissa A., primary, Woods, Nicholas T., primary, Tyrer, Jonathan P., primary, Mendoza-Fandiño, Gustavo, primary, Lawrenson, Kate, primary, Hazelett, Dennis J., primary, Najafabadi, Hamed S., primary, Gjyshi, Anxhela, primary, Carvalho, Renato S., primary, Lyra, Paulo C., primary, Coetzee, Simon G., primary, Shen, Howard C., primary, Yang, Ally W., primary, Earp, Madalene A., primary, Yoder, Sean J., primary, Risch, Harvey, primary, Chenevix-Trench, Georgia, primary, Ramus, Susan J., primary, Phelan, Catherine M., primary, Coetzee, Gerhard A., primary, Noushmehr, Houtan, primary, Hughes, Timothy R., primary, Sellers, Thomas A., primary, Goode, Ellen L., primary, Pharoah, Paul D., primary, Gayther, Simon A., primary, and Monteiro, Alvaro N.A., primary
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29. Supplementary Tables S1-6, Figures S1-2 from Network-Based Integration of GWAS and Gene Expression Identifies a HOX-Centric Network Associated with Serous Ovarian Cancer Risk
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Kar, Siddhartha P., primary, Tyrer, Jonathan P., primary, Li, Qiyuan, primary, Lawrenson, Kate, primary, Aben, Katja K.H., primary, Anton-Culver, Hoda, primary, Antonenkova, Natalia, primary, Chenevix-Trench, Georgia, primary, Baker, Helen, primary, Bandera, Elisa V., primary, Bean, Yukie T., primary, Beckmann, Matthias W., primary, Berchuck, Andrew, primary, Bisogna, Maria, primary, Bjørge, Line, primary, Bogdanova, Natalia, primary, Brinton, Louise, primary, Brooks-Wilson, Angela, primary, Butzow, Ralf, primary, Campbell, Ian, primary, Carty, Karen, primary, Chang-Claude, Jenny, primary, Chen, Yian Ann, primary, Chen, Zhihua, primary, Cook, Linda S., primary, Cramer, Daniel, primary, Cunningham, Julie M., primary, Cybulski, Cezary, primary, Dansonka-Mieszkowska, Agnieszka, primary, Dennis, Joe, primary, Dicks, Ed, primary, Doherty, Jennifer A., primary, Dörk, Thilo, primary, du Bois, Andreas, primary, Dürst, Matthias, primary, Eccles, Diana, primary, Easton, Douglas F., primary, Edwards, Robert P., primary, Ekici, Arif B., primary, Fasching, Peter A., primary, Fridley, Brooke L., primary, Gao, Yu-Tang, primary, Gentry-Maharaj, Aleksandra, primary, Giles, Graham G., primary, Glasspool, Rosalind, primary, Goode, Ellen L., primary, Goodman, Marc T., primary, Grownwald, Jacek, primary, Harrington, Patricia, primary, Harter, Philipp, primary, Hein, Alexander, primary, Heitz, Florian, primary, Hildebrandt, Michelle A.T., primary, Hillemanns, Peter, primary, Hogdall, Estrid, primary, Hogdall, Claus K., primary, Hosono, Satoyo, primary, Iversen, Edwin S., primary, Jakubowska, Anna, primary, Paul, James, primary, Jensen, Allan, primary, Ji, Bu-Tian, primary, Karlan, Beth Y., primary, Kjaer, Susanne K., primary, Kelemen, Linda E., primary, Kellar, Melissa, primary, Kelley, Joseph, primary, Kiemeney, Lambertus A., primary, Krakstad, Camilla, primary, Kupryjanczyk, Jolanta, primary, Lambrechts, Diether, primary, Lambrechts, Sandrina, primary, Le, Nhu D., primary, Lee, Alice W., primary, Lele, Shashi, primary, Leminen, Arto, primary, Lester, Jenny, primary, Levine, Douglas A., primary, Liang, Dong, primary, Lissowska, Jolanta, primary, Lu, Karen, primary, Lubinski, Jan, primary, Lundvall, Lene, primary, Massuger, Leon, primary, Matsuo, Keitaro, primary, McGuire, Valerie, primary, McLaughlin, John R., primary, McNeish, Iain A., primary, Menon, Usha, primary, Modugno, Francesmary, primary, Moysich, Kirsten B., primary, Narod, Steven A., primary, Nedergaard, Lotte, primary, Ness, Roberta B., primary, Nevanlinna, Heli, primary, Odunsi, Kunle, primary, Olson, Sara H., primary, Orlow, Irene, primary, Orsulic, Sandra, primary, Weber, Rachel Palmieri, primary, Pearce, Celeste Leigh, primary, Pejovic, Tanja, primary, Pelttari, Liisa M., primary, Permuth-Wey, Jennifer, primary, Phelan, Catherine M., primary, Pike, Malcolm C., primary, Poole, Elizabeth M., primary, Ramus, Susan J., primary, Risch, Harvey A., primary, Rosen, Barry, primary, Rossing, Mary Anne, primary, Rothstein, Joseph H., primary, Rudolph, Anja, primary, Runnebaum, Ingo B., primary, Rzepecka, Iwona K., primary, Salvesen, Helga B., primary, Schildkraut, Joellen M., primary, Schwaab, Ira, primary, Shu, Xiao-Ou, primary, Shvetsov, Yurii B., primary, Siddiqui, Nadeem, primary, Sieh, Weiva, primary, Song, Honglin, primary, Southey, Melissa C., primary, Sucheston-Campbell, Lara E., primary, Tangen, Ingvild L., primary, Teo, Soo-Hwang, primary, Terry, Kathryn L., primary, Thompson, Pamela J., primary, Timorek, Agnieszka, primary, Tsai, Ya-Yu, primary, Tworoger, Shelley S., primary, van Altena, Anne M., primary, Van Nieuwenhuysen, Els, primary, Vergote, Ignace, primary, Vierkant, Robert A., primary, Wang-Gohrke, Shan, primary, Walsh, Christine, primary, Wentzensen, Nicolas, primary, Whittemore, Alice S., primary, Wicklund, Kristine G., primary, Wilkens, Lynne R., primary, Woo, Yin-Ling, primary, Wu, Xifeng, primary, Wu, Anna, primary, Yang, Hannah, primary, Zheng, Wei, primary, Ziogas, Argyrios, primary, Sellers, Thomas A., primary, Monteiro, Alvaro N.A., primary, Freedman, Matthew L., primary, Gayther, Simon A., primary, and Pharoah, Paul D.P., primary
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30. Data from Functional Analysis and Fine Mapping of the 9p22.2 Ovarian Cancer Susceptibility Locus
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Buckley, Melissa A., primary, Woods, Nicholas T., primary, Tyrer, Jonathan P., primary, Mendoza-Fandiño, Gustavo, primary, Lawrenson, Kate, primary, Hazelett, Dennis J., primary, Najafabadi, Hamed S., primary, Gjyshi, Anxhela, primary, Carvalho, Renato S., primary, Lyra, Paulo C., primary, Coetzee, Simon G., primary, Shen, Howard C., primary, Yang, Ally W., primary, Earp, Madalene A., primary, Yoder, Sean J., primary, Risch, Harvey, primary, Chenevix-Trench, Georgia, primary, Ramus, Susan J., primary, Phelan, Catherine M., primary, Coetzee, Gerhard A., primary, Noushmehr, Houtan, primary, Hughes, Timothy R., primary, Sellers, Thomas A., primary, Goode, Ellen L., primary, Pharoah, Paul D., primary, Gayther, Simon A., primary, and Monteiro, Alvaro N.A., primary
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31. Supplementary Figures 1-5, Tables 1-8 from Genome-wide Analysis Identifies Novel Loci Associated with Ovarian Cancer Outcomes: Findings from the Ovarian Cancer Association Consortium
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Johnatty, Sharon E., primary, Tyrer, Jonathan P., primary, Kar, Siddhartha, primary, Beesley, Jonathan, primary, Lu, Yi, primary, Gao, Bo, primary, Fasching, Peter A., primary, Hein, Alexander, primary, Ekici, Arif B., primary, Beckmann, Matthias W., primary, Lambrechts, Diether, primary, Van Nieuwenhuysen, Els, primary, Vergote, Ignace, primary, Lambrechts, Sandrina, primary, Rossing, Mary Anne, primary, Doherty, Jennifer A., primary, Chang-Claude, Jenny, primary, Modugno, Francesmary, primary, Ness, Roberta B., primary, Moysich, Kirsten B., primary, Levine, Douglas A., primary, Kiemeney, Lambertus A., primary, Massuger, Leon F.A.G., primary, Gronwald, Jacek, primary, Lubiński, Jan, primary, Jakubowska, Anna, primary, Cybulski, Cezary, primary, Brinton, Louise, primary, Lissowska, Jolanta, primary, Wentzensen, Nicolas, primary, Song, Honglin, primary, Rhenius, Valerie, primary, Campbell, Ian, primary, Eccles, Diana, primary, Sieh, Weiva, primary, Whittemore, Alice S., primary, McGuire, Valerie, primary, Rothstein, Joseph H., primary, Sutphen, Rebecca, primary, Anton-Culver, Hoda, primary, Ziogas, Argyrios, primary, Gayther, Simon A., primary, Gentry-Maharaj, Aleksandra, primary, Menon, Usha, primary, Ramus, Susan J., primary, Pearce, Celeste L., primary, Pike, Malcolm C., primary, Stram, Daniel O., primary, Wu, Anna H., primary, Kupryjanczyk, Jolanta, primary, Dansonka-Mieszkowska, Agnieszka, primary, Rzepecka, Iwona K., primary, Spiewankiewicz, Beata, primary, Goodman, Marc T., primary, Wilkens, Lynne R., primary, Carney, Michael E., primary, Thompson, Pamela J., primary, Heitz, Florian, primary, du Bois, Andreas, primary, Schwaab, Ira, primary, Harter, Philipp, primary, Pisterer, Jacobus, primary, Hillemanns, Peter, primary, Karlan, Beth Y., primary, Walsh, Christine, primary, Lester, Jenny, primary, Orsulic, Sandra, primary, Winham, Stacey J., primary, Earp, Madalene, primary, Larson, Melissa C., primary, Fogarty, Zachary C., primary, Høgdall, Estrid, primary, Jensen, Allan, primary, Kjaer, Susanne Kruger, primary, Fridley, Brooke L., primary, Cunningham, Julie M., primary, Vierkant, Robert A., primary, Schildkraut, Joellen M., primary, Iversen, Edwin S., primary, Terry, Kathryn L., primary, Cramer, Daniel W., primary, Bandera, Elisa V., primary, Orlow, Irene, primary, Pejovic, Tanja, primary, Bean, Yukie, primary, Høgdall, Claus, primary, Lundvall, Lene, primary, McNeish, Ian, primary, Paul, James, primary, Carty, Karen, primary, Siddiqui, Nadeem, primary, Glasspool, Rosalind, primary, Sellers, Thomas, primary, Kennedy, Catherine, primary, Chiew, Yoke-Eng, primary, Berchuck, Andrew, primary, MacGregor, Stuart, primary, Pharoah, Paul D.P., primary, Goode, Ellen L., primary, deFazio, Anna, primary, Webb, Penelope M., primary, and Chenevix-Trench, Georgia, primary
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32. Supplementary Table 1 from Functional Analysis and Fine Mapping of the 9p22.2 Ovarian Cancer Susceptibility Locus
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Buckley, Melissa A., primary, Woods, Nicholas T., primary, Tyrer, Jonathan P., primary, Mendoza-Fandiño, Gustavo, primary, Lawrenson, Kate, primary, Hazelett, Dennis J., primary, Najafabadi, Hamed S., primary, Gjyshi, Anxhela, primary, Carvalho, Renato S., primary, Lyra, Paulo C., primary, Coetzee, Simon G., primary, Shen, Howard C., primary, Yang, Ally W., primary, Earp, Madalene A., primary, Yoder, Sean J., primary, Risch, Harvey, primary, Chenevix-Trench, Georgia, primary, Ramus, Susan J., primary, Phelan, Catherine M., primary, Coetzee, Gerhard A., primary, Noushmehr, Houtan, primary, Hughes, Timothy R., primary, Sellers, Thomas A., primary, Goode, Ellen L., primary, Pharoah, Paul D., primary, Gayther, Simon A., primary, and Monteiro, Alvaro N.A., primary
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33. Supplemental Tables 1 - 7 from Assessment of Multifactor Gene–Environment Interactions and Ovarian Cancer Risk: Candidate Genes, Obesity, and Hormone-Related Risk Factors
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Usset, Joseph L., primary, Raghavan, Rama, primary, Tyrer, Jonathan P., primary, McGuire, Valerie, primary, Sieh, Weiva, primary, Webb, Penelope, primary, Chang-Claude, Jenny, primary, Rudolph, Anja, primary, Anton-Culver, Hoda, primary, Berchuck, Andrew, primary, Brinton, Louise, primary, Cunningham, Julie M., primary, DeFazio, Anna, primary, Doherty, Jennifer A., primary, Edwards, Robert P., primary, Gayther, Simon A., primary, Gentry-Maharaj, Aleksandra, primary, Goodman, Marc T., primary, Høgdall, Estrid, primary, Jensen, Allan, primary, Johnatty, Sharon E., primary, Kiemeney, Lambertus A., primary, Kjaer, Susanne K., primary, Larson, Melissa C., primary, Lurie, Galina, primary, Massuger, Leon, primary, Menon, Usha, primary, Modugno, Francesmary, primary, Moysich, Kirsten B., primary, Ness, Roberta B., primary, Pike, Malcolm C., primary, Ramus, Susan J., primary, Rossing, Mary Anne, primary, Rothstein, Joseph, primary, Song, Honglin, primary, Thompson, Pamela J., primary, van den Berg, David J., primary, Vierkant, Robert A., primary, Wang-Gohrke, Shan, primary, Wentzensen, Nicolas, primary, Whittemore, Alice S., primary, Wilkens, Lynne R., primary, Wu, Anna H., primary, Yang, Hannah, primary, Pearce, Celeste Leigh, primary, Schildkraut, Joellen M., primary, Pharoah, Paul, primary, Goode, Ellen L., primary, and Fridley, Brooke L., primary
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34. Supplemental Table 2. Average BMIs in the ANECS, SEARCH and iCOGS endometrial cancer datasets. from Genetic Risk Score Mendelian Randomization Shows that Obesity Measured as Body Mass Index, but not Waist:Hip Ratio, Is Causal for Endometrial Cancer
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Painter, Jodie N., primary, O'Mara, Tracy A., primary, Marquart, Louise, primary, Webb, Penelope M., primary, Attia, John, primary, Medland, Sarah E., primary, Cheng, Timothy, primary, Dennis, Joe, primary, Holliday, Elizabeth G., primary, McEvoy, Mark, primary, Scott, Rodney J., primary, Ahmed, Shahana, primary, Healey, Catherine S., primary, Shah, Mitul, primary, Gorman, Maggie, primary, Martin, Lynn, primary, Hodgson, Shirley V., primary, Beckmann, Matthias W., primary, Ekici, Arif B., primary, Fasching, Peter A., primary, Hein, Alexander, primary, Rübner, Matthias, primary, Czene, Kamila, primary, Darabi, Hatef, primary, Hall, Per, primary, Li, Jingmei, primary, Dörk, Thilo, primary, Dürst, Matthias, primary, Hillemanns, Peter, primary, Runnebaum, Ingo B., primary, Amant, Frederic, primary, Annibali, Daniela, primary, Depreeuw, Jeroen, primary, Lambrechts, Diether, primary, Neven, Patrick, primary, Cunningham, Julie M., primary, Dowdy, Sean C., primary, Goode, Ellen L., primary, Fridley, Brooke L., primary, Winham, Stacey J., primary, Njølstad, Tormund S., primary, Salvesen, Helga B., primary, Trovik, Jone, primary, Werner, Henrica M.J., primary, Ashton, Katie A., primary, Otton, Geoffrey, primary, Proietto, Anthony, primary, Mints, Miriam, primary, Tham, Emma, primary, Bolla, Manjeet K., primary, Michailidou, Kyriaki, primary, Wang, Qin, primary, Tyrer, Jonathan P., primary, Hopper, John L., primary, Peto, Julian, primary, Swerdlow, Anthony J., primary, Burwinkel, Barbara, primary, Brenner, Hermann, primary, Meindl, Alfons, primary, Brauch, Hiltrud, primary, Lindblom, Annika, primary, Chang-Claude, Jenny, primary, Couch, Fergus J., primary, Giles, Graham G., primary, Kristensen, Vessela N., primary, Cox, Angela, primary, Pharoah, Paul D.P., primary, Tomlinson, Ian, primary, Dunning, Alison M., primary, Easton, Douglas F., primary, Thompson, Deborah J., primary, and Spurdle, Amanda B., primary
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35. Supplementary Material: Funding, Acknowledgements, Consortia, and Bioinformatics Tools Funding sources from Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations
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Fehringer, Gordon, primary, Kraft, Peter, primary, Pharoah, Paul D., primary, Eeles, Rosalind A., primary, Chatterjee, Nilanjan, primary, Schumacher, Fredrick R., primary, Schildkraut, Joellen M., primary, Lindström, Sara, primary, Brennan, Paul, primary, Bickeböller, Heike, primary, Houlston, Richard S., primary, Landi, Maria Teresa, primary, Caporaso, Neil, primary, Risch, Angela, primary, Amin Al Olama, Ali, primary, Berndt, Sonja I., primary, Giovannucci, Edward L., primary, Grönberg, Henrik, primary, Kote-Jarai, Zsofia, primary, Ma, Jing, primary, Muir, Kenneth, primary, Stampfer, Meir J., primary, Stevens, Victoria L., primary, Wiklund, Fredrik, primary, Willett, Walter C., primary, Goode, Ellen L., primary, Permuth, Jennifer B., primary, Risch, Harvey A., primary, Reid, Brett M., primary, Bezieau, Stephane, primary, Brenner, Hermann, primary, Chan, Andrew T., primary, Chang-Claude, Jenny, primary, Hudson, Thomas J., primary, Kocarnik, Jonathan K., primary, Newcomb, Polly A., primary, Schoen, Robert E., primary, Slattery, Martha L., primary, White, Emily, primary, Adank, Muriel A., primary, Ahsan, Habibul, primary, Aittomäki, Kristiina, primary, Baglietto, Laura, primary, Blomquist, Carl, primary, Canzian, Federico, primary, Czene, Kamila, primary, dos-Santos-Silva, Isabel, primary, Eliassen, A. Heather, primary, Figueroa, Jonine D., primary, Flesch-Janys, Dieter, primary, Fletcher, Olivia, primary, Garcia-Closas, Montserrat, primary, Gaudet, Mia M., primary, Johnson, Nichola, primary, Hall, Per, primary, Hazra, Aditi, primary, Hein, Rebecca, primary, Hofman, Albert, primary, Hopper, John L., primary, Irwanto, Astrid, primary, Johansson, Mattias, primary, Kaaks, Rudolf, primary, Kibriya, Muhammad G., primary, Lichtner, Peter, primary, Liu, Jianjun, primary, Lund, Eiliv, primary, Makalic, Enes, primary, Meindl, Alfons, primary, Müller-Myhsok, Bertram, primary, Muranen, Taru A., primary, Nevanlinna, Heli, primary, Peeters, Petra H., primary, Peto, Julian, primary, Prentice, Ross L., primary, Rahman, Nazneen, primary, Sanchez, Maria Jose, primary, Schmidt, Daniel F., primary, Schmutzler, Rita K., primary, Southey, Melissa C., primary, Tamimi, Rulla, primary, Travis, Ruth C., primary, Turnbull, Clare, primary, Uitterlinden, Andre G., primary, Wang, Zhaoming, primary, Whittemore, Alice S., primary, Yang, Xiaohong R., primary, Zheng, Wei, primary, Buchanan, Daniel D., primary, Casey, Graham, primary, Conti, David V., primary, Edlund, Christopher K., primary, Gallinger, Steven, primary, Haile, Robert W., primary, Jenkins, Mark, primary, Le Marchand, Loïc, primary, Li, Li, primary, Lindor, Noralene M., primary, Schmit, Stephanie L., primary, Thibodeau, Stephen N., primary, Woods, Michael O., primary, Rafnar, Thorunn, primary, Gudmundsson, Julius, primary, Stacey, Simon N., primary, Stefansson, Kari, primary, Sulem, Patrick, primary, Chen, Y. Ann, primary, Tyrer, Jonathan P., primary, Christiani, David C., primary, Wei, Yongyue, primary, Shen, Hongbing, primary, Hu, Zhibin, primary, Shu, Xiao-Ou, primary, Shiraishi, Kouya, primary, Takahashi, Atsushi, primary, Bossé, Yohan, primary, Obeidat, Ma'en, primary, Nickle, David, primary, Timens, Wim, primary, Freedman, Matthew L., primary, Li, Qiyuan, primary, Seminara, Daniela, primary, Chanock, Stephen J., primary, Gong, Jian, primary, Peters, Ulrike, primary, Gruber, Stephen B., primary, Amos, Christopher I., primary, Sellers, Thomas A., primary, Easton, Douglas F., primary, Hunter, David J., primary, Haiman, Christopher A., primary, Henderson, Brian E., primary, and Hung, Rayjean J., primary
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36. Supplementary Text for: Genetic risk score Mendelian randomization shows that obesity measured as body mass index, but not waist:hip ratio, is causal for endometrial cancer from Genetic Risk Score Mendelian Randomization Shows that Obesity Measured as Body Mass Index, but not Waist:Hip Ratio, Is Causal for Endometrial Cancer
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Painter, Jodie N., primary, O'Mara, Tracy A., primary, Marquart, Louise, primary, Webb, Penelope M., primary, Attia, John, primary, Medland, Sarah E., primary, Cheng, Timothy, primary, Dennis, Joe, primary, Holliday, Elizabeth G., primary, McEvoy, Mark, primary, Scott, Rodney J., primary, Ahmed, Shahana, primary, Healey, Catherine S., primary, Shah, Mitul, primary, Gorman, Maggie, primary, Martin, Lynn, primary, Hodgson, Shirley V., primary, Beckmann, Matthias W., primary, Ekici, Arif B., primary, Fasching, Peter A., primary, Hein, Alexander, primary, Rübner, Matthias, primary, Czene, Kamila, primary, Darabi, Hatef, primary, Hall, Per, primary, Li, Jingmei, primary, Dörk, Thilo, primary, Dürst, Matthias, primary, Hillemanns, Peter, primary, Runnebaum, Ingo B., primary, Amant, Frederic, primary, Annibali, Daniela, primary, Depreeuw, Jeroen, primary, Lambrechts, Diether, primary, Neven, Patrick, primary, Cunningham, Julie M., primary, Dowdy, Sean C., primary, Goode, Ellen L., primary, Fridley, Brooke L., primary, Winham, Stacey J., primary, Njølstad, Tormund S., primary, Salvesen, Helga B., primary, Trovik, Jone, primary, Werner, Henrica M.J., primary, Ashton, Katie A., primary, Otton, Geoffrey, primary, Proietto, Anthony, primary, Mints, Miriam, primary, Tham, Emma, primary, Bolla, Manjeet K., primary, Michailidou, Kyriaki, primary, Wang, Qin, primary, Tyrer, Jonathan P., primary, Hopper, John L., primary, Peto, Julian, primary, Swerdlow, Anthony J., primary, Burwinkel, Barbara, primary, Brenner, Hermann, primary, Meindl, Alfons, primary, Brauch, Hiltrud, primary, Lindblom, Annika, primary, Chang-Claude, Jenny, primary, Couch, Fergus J., primary, Giles, Graham G., primary, Kristensen, Vessela N., primary, Cox, Angela, primary, Pharoah, Paul D.P., primary, Tomlinson, Ian, primary, Dunning, Alison M., primary, Easton, Douglas F., primary, Thompson, Deborah J., primary, and Spurdle, Amanda B., primary
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37. Data from Assessment of Multifactor Gene–Environment Interactions and Ovarian Cancer Risk: Candidate Genes, Obesity, and Hormone-Related Risk Factors
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Usset, Joseph L., primary, Raghavan, Rama, primary, Tyrer, Jonathan P., primary, McGuire, Valerie, primary, Sieh, Weiva, primary, Webb, Penelope, primary, Chang-Claude, Jenny, primary, Rudolph, Anja, primary, Anton-Culver, Hoda, primary, Berchuck, Andrew, primary, Brinton, Louise, primary, Cunningham, Julie M., primary, DeFazio, Anna, primary, Doherty, Jennifer A., primary, Edwards, Robert P., primary, Gayther, Simon A., primary, Gentry-Maharaj, Aleksandra, primary, Goodman, Marc T., primary, Høgdall, Estrid, primary, Jensen, Allan, primary, Johnatty, Sharon E., primary, Kiemeney, Lambertus A., primary, Kjaer, Susanne K., primary, Larson, Melissa C., primary, Lurie, Galina, primary, Massuger, Leon, primary, Menon, Usha, primary, Modugno, Francesmary, primary, Moysich, Kirsten B., primary, Ness, Roberta B., primary, Pike, Malcolm C., primary, Ramus, Susan J., primary, Rossing, Mary Anne, primary, Rothstein, Joseph, primary, Song, Honglin, primary, Thompson, Pamela J., primary, van den Berg, David J., primary, Vierkant, Robert A., primary, Wang-Gohrke, Shan, primary, Wentzensen, Nicolas, primary, Whittemore, Alice S., primary, Wilkens, Lynne R., primary, Wu, Anna H., primary, Yang, Hannah, primary, Pearce, Celeste Leigh, primary, Schildkraut, Joellen M., primary, Pharoah, Paul, primary, Goode, Ellen L., primary, and Fridley, Brooke L., primary
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38. Supplementary Table 2 from Functional Analysis and Fine Mapping of the 9p22.2 Ovarian Cancer Susceptibility Locus
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Buckley, Melissa A., primary, Woods, Nicholas T., primary, Tyrer, Jonathan P., primary, Mendoza-Fandiño, Gustavo, primary, Lawrenson, Kate, primary, Hazelett, Dennis J., primary, Najafabadi, Hamed S., primary, Gjyshi, Anxhela, primary, Carvalho, Renato S., primary, Lyra, Paulo C., primary, Coetzee, Simon G., primary, Shen, Howard C., primary, Yang, Ally W., primary, Earp, Madalene A., primary, Yoder, Sean J., primary, Risch, Harvey, primary, Chenevix-Trench, Georgia, primary, Ramus, Susan J., primary, Phelan, Catherine M., primary, Coetzee, Gerhard A., primary, Noushmehr, Houtan, primary, Hughes, Timothy R., primary, Sellers, Thomas A., primary, Goode, Ellen L., primary, Pharoah, Paul D., primary, Gayther, Simon A., primary, and Monteiro, Alvaro N.A., primary
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39. Data from Genome-wide Analysis Identifies Novel Loci Associated with Ovarian Cancer Outcomes: Findings from the Ovarian Cancer Association Consortium
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Johnatty, Sharon E., primary, Tyrer, Jonathan P., primary, Kar, Siddhartha, primary, Beesley, Jonathan, primary, Lu, Yi, primary, Gao, Bo, primary, Fasching, Peter A., primary, Hein, Alexander, primary, Ekici, Arif B., primary, Beckmann, Matthias W., primary, Lambrechts, Diether, primary, Van Nieuwenhuysen, Els, primary, Vergote, Ignace, primary, Lambrechts, Sandrina, primary, Rossing, Mary Anne, primary, Doherty, Jennifer A., primary, Chang-Claude, Jenny, primary, Modugno, Francesmary, primary, Ness, Roberta B., primary, Moysich, Kirsten B., primary, Levine, Douglas A., primary, Kiemeney, Lambertus A., primary, Massuger, Leon F.A.G., primary, Gronwald, Jacek, primary, Lubiński, Jan, primary, Jakubowska, Anna, primary, Cybulski, Cezary, primary, Brinton, Louise, primary, Lissowska, Jolanta, primary, Wentzensen, Nicolas, primary, Song, Honglin, primary, Rhenius, Valerie, primary, Campbell, Ian, primary, Eccles, Diana, primary, Sieh, Weiva, primary, Whittemore, Alice S., primary, McGuire, Valerie, primary, Rothstein, Joseph H., primary, Sutphen, Rebecca, primary, Anton-Culver, Hoda, primary, Ziogas, Argyrios, primary, Gayther, Simon A., primary, Gentry-Maharaj, Aleksandra, primary, Menon, Usha, primary, Ramus, Susan J., primary, Pearce, Celeste L., primary, Pike, Malcolm C., primary, Stram, Daniel O., primary, Wu, Anna H., primary, Kupryjanczyk, Jolanta, primary, Dansonka-Mieszkowska, Agnieszka, primary, Rzepecka, Iwona K., primary, Spiewankiewicz, Beata, primary, Goodman, Marc T., primary, Wilkens, Lynne R., primary, Carney, Michael E., primary, Thompson, Pamela J., primary, Heitz, Florian, primary, du Bois, Andreas, primary, Schwaab, Ira, primary, Harter, Philipp, primary, Pisterer, Jacobus, primary, Hillemanns, Peter, primary, Karlan, Beth Y., primary, Walsh, Christine, primary, Lester, Jenny, primary, Orsulic, Sandra, primary, Winham, Stacey J., primary, Earp, Madalene, primary, Larson, Melissa C., primary, Fogarty, Zachary C., primary, Høgdall, Estrid, primary, Jensen, Allan, primary, Kjaer, Susanne Kruger, primary, Fridley, Brooke L., primary, Cunningham, Julie M., primary, Vierkant, Robert A., primary, Schildkraut, Joellen M., primary, Iversen, Edwin S., primary, Terry, Kathryn L., primary, Cramer, Daniel W., primary, Bandera, Elisa V., primary, Orlow, Irene, primary, Pejovic, Tanja, primary, Bean, Yukie, primary, Høgdall, Claus, primary, Lundvall, Lene, primary, McNeish, Ian, primary, Paul, James, primary, Carty, Karen, primary, Siddiqui, Nadeem, primary, Glasspool, Rosalind, primary, Sellers, Thomas, primary, Kennedy, Catherine, primary, Chiew, Yoke-Eng, primary, Berchuck, Andrew, primary, MacGregor, Stuart, primary, Pharoah, Paul D.P., primary, Goode, Ellen L., primary, deFazio, Anna, primary, Webb, Penelope M., primary, and Chenevix-Trench, Georgia, primary
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40. Supplementary Table 4 from Functional Analysis and Fine Mapping of the 9p22.2 Ovarian Cancer Susceptibility Locus
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Buckley, Melissa A., primary, Woods, Nicholas T., primary, Tyrer, Jonathan P., primary, Mendoza-Fandiño, Gustavo, primary, Lawrenson, Kate, primary, Hazelett, Dennis J., primary, Najafabadi, Hamed S., primary, Gjyshi, Anxhela, primary, Carvalho, Renato S., primary, Lyra, Paulo C., primary, Coetzee, Simon G., primary, Shen, Howard C., primary, Yang, Ally W., primary, Earp, Madalene A., primary, Yoder, Sean J., primary, Risch, Harvey, primary, Chenevix-Trench, Georgia, primary, Ramus, Susan J., primary, Phelan, Catherine M., primary, Coetzee, Gerhard A., primary, Noushmehr, Houtan, primary, Hughes, Timothy R., primary, Sellers, Thomas A., primary, Goode, Ellen L., primary, Pharoah, Paul D., primary, Gayther, Simon A., primary, and Monteiro, Alvaro N.A., primary
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41. Identification of a Locus Near ULK1 Associated With Progression-Free Survival in Ovarian Cancer
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Quinn, Michael C.J., primary, McCue, Karen, additional, Shi, Wei, additional, Johnatty, Sharon E., additional, Beesley, Jonathan, additional, Civitarese, Andrew, additional, O'Mara, Tracy A., additional, Glubb, Dylan M., additional, Tyrer, Jonathan P., additional, Armasu, Sebastian M., additional, Ong, Jue-Sheng, additional, Gharahkhani, Puya, additional, Lu, Yi, additional, Gao, Bo, additional, Patch, Ann-Marie, additional, Fasching, Peter A., additional, Beckmann, Matthias W., additional, Lambrechts, Diether, additional, Vergote, Ignace, additional, Velez Edwards, Digna R., additional, Beeghly-Fadiel, Alicia, additional, Benitez, Javier, additional, Garcia, Maria J., additional, Goodman, Marc T., additional, Dörk, Thilo, additional, Dürst, Matthias, additional, Modugno, Francesmary, additional, Moysich, Kirsten, additional, du Bois, Andreas, additional, Pfisterer, Jacobus, additional, Bauman, Klaus, additional, Karlan, Beth Y., additional, Lester, Jenny, additional, Cunningham, Julie M., additional, Larson, Melissa C., additional, McCauley, Bryan M., additional, Kjaer, Susanne K., additional, Jensen, Allan, additional, Hogdall, Claus K., additional, Hogdall, Estrid, additional, Schildkraut, Joellen M., additional, Riggan, Marjorie J., additional, Berchuck, Andrew, additional, Cramer, Daniel W., additional, Terry, Kathryn L., additional, Bjorge, Line, additional, Webb, Penelope M., additional, Friedlander, Michael, additional, Pejovic, Tanja, additional, Moffitt, Melissa, additional, Glasspool, Rosalind, additional, May, Taymaa, additional, Ene, Gabrielle E.V., additional, Huntsman, David G., additional, Woo, Michelle, additional, Carney, Michael E., additional, Hinsley, Samantha, additional, Heitz, Florian, additional, Fereday, Sian, additional, Kennedy, Catherine J., additional, Edwards, Stacey L., additional, Winham, Stacey J., additional, deFazio, Anna, additional, Pharoah, Paul D.P., additional, Goode, Ellen L., additional, MacGregor, Stuart, additional, and Chenevix-Trench, Georgia, additional
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- 2021
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42. Functional Analysis and Fine Mapping of the 9p22.2 Ovarian Cancer Susceptibility Locus
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Buckley, Melissa A, Woods, Nicholas T, Tyrer, Jonathan P, Mendoza-Fandiño, Gustavo, Lawrenson, Kate, Hazelett, Dennis J, Najafabadi, Hamed S, Gjyshi, Anxhela, Carvalho, Renato S, Lyra, Paulo C, Coetzee, Simon G, Shen, Howard C, Yang, Ally W, Earp, Madalene A, Yoder, Sean J, Risch, Harvey, Chenevix-Trench, Georgia, Ramus, Susan J, Phelan, Catherine M, Coetzee, Gerhard A, Noushmehr, Houtan, Hughes, Timothy R, Sellers, Thomas A, Goode, Ellen L, Pharoah, Paul D, Gayther, Simon A, Monteiro, Alvaro NA, Ovarian Cancer Association Consortium, Lawrenson, Kate [0000-0002-6469-2515], Hazelett, Dennis J [0000-0003-0749-9935], Najafabadi, Hamed S [0000-0003-2735-4231], Coetzee, Simon G [0000-0003-4267-5930], Yoder, Sean J [0000-0003-0005-7798], Coetzee, Gerhard A [0000-0003-4267-5930], Noushmehr, Houtan [0000-0003-4051-8114], and Apollo - University of Cambridge Repository
- Subjects
Ovarian Cancer Association Consortium ,Oncology and Carcinogenesis ,Cystadenocarcinoma ,Cell Cycle Proteins ,Carcinoma, Ovarian Epithelial ,Polymorphism, Single Nucleotide ,Chromosomes ,Linkage Disequilibrium ,Cell Line ,Rare Diseases ,Ovarian Epithelial ,Cell Line, Tumor ,Genetics ,2.1 Biological and endogenous factors ,Humans ,Genetic Predisposition to Disease ,Oncology & Carcinogenesis ,Polymorphism ,Aetiology ,Cancer ,Ovarian Neoplasms ,Tumor ,Base Sequence ,Prevention ,Carcinoma ,Human Genome ,Serous ,Chromosome Mapping ,DNA ,Single Nucleotide ,DNA, Neoplasm ,Ovarian Cancer ,Cystadenocarcinoma, Serous ,DNA-Binding Proteins ,HEK293 Cells ,Neoplasm ,Female ,Chromosomes, Human, Pair 9 ,Human ,Pair 9 ,Biotechnology ,Genome-Wide Association Study - Abstract
Genome-wide association studies have identified 40 ovarian cancer risk loci. However, the mechanisms underlying these associations remain elusive. In this study, we conducted a two-pronged approach to identify candidate causal SNPs and assess underlying biological mechanisms at chromosome 9p22.2, the first and most statistically significant associated locus for ovarian cancer susceptibility. Three transcriptional regulatory elements with allele-specific effects and a scaffold/matrix attachment region were characterized and, through physical DNA interactions, BNC2 was established as the most likely target gene. We determined the consensus binding sequence for BNC2 in vitro, verified its enrichment in BNC2 ChIP-seq regions, and validated a set of its downstream target genes. Fine-mapping by dense regional genotyping in over 15,000 ovarian cancer cases and 30,000 controls identified SNPs in the scaffold/matrix attachment region as among the most likely causal variants. This study reveals a comprehensive regulatory landscape at 9p22.2 and proposes a likely mechanism of susceptibility to ovarian cancer. SIGNIFICANCE: Mapping the 9p22.2 ovarian cancer risk locus identifies BNC2 as an ovarian cancer risk gene.See related commentary by Choi and Brown, p. 439.
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- 2018
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43. Functional Analysis and Fine Mapping of the 9p22.2 Ovarian Cancer Susceptibility Locus
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Buckley, Melissa A., primary, Woods, Nicholas T., additional, Tyrer, Jonathan P., additional, Mendoza-Fandiño, Gustavo, additional, Lawrenson, Kate, additional, Hazelett, Dennis J., additional, Najafabadi, Hamed S., additional, Gjyshi, Anxhela, additional, Carvalho, Renato S., additional, Lyra, Paulo C., additional, Coetzee, Simon G., additional, Shen, Howard C., additional, Yang, Ally W., additional, Earp, Madalene A., additional, Yoder, Sean J., additional, Risch, Harvey, additional, Chenevix-Trench, Georgia, additional, Ramus, Susan J., additional, Phelan, Catherine M., additional, Coetzee, Gerhard A., additional, Noushmehr, Houtan, additional, Hughes, Timothy R., additional, Sellers, Thomas A., additional, Goode, Ellen L., additional, Pharoah, Paul D., additional, Gayther, Simon A., additional, and Monteiro, Alvaro N.A., additional
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- 2019
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44. Genetic Data from Nearly 63,000 Women of European Descent Predicts DNA Methylation Biomarkers and Epithelial Ovarian Cancer Risk
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Yang, Yaohua, primary, Wu, Lang, additional, Shu, Xiang, additional, Lu, Yingchang, additional, Shu, Xiao-Ou, additional, Cai, Qiuyin, additional, Beeghly-Fadiel, Alicia, additional, Li, Bingshan, additional, Ye, Fei, additional, Berchuck, Andrew, additional, Anton-Culver, Hoda, additional, Banerjee, Susana, additional, Benitez, Javier, additional, Bjørge, Line, additional, Brenton, James D., additional, Butzow, Ralf, additional, Campbell, Ian G., additional, Chang-Claude, Jenny, additional, Chen, Kexin, additional, Cook, Linda S., additional, Cramer, Daniel W., additional, deFazio, Anna, additional, Dennis, Joe, additional, Doherty, Jennifer A., additional, Dörk, Thilo, additional, Eccles, Diana M., additional, Edwards, Digna Velez, additional, Fasching, Peter A., additional, Fortner, Renée T., additional, Gayther, Simon A., additional, Giles, Graham G., additional, Glasspool, Rosalind M., additional, Goode, Ellen L., additional, Goodman, Marc T., additional, Gronwald, Jacek, additional, Harris, Holly R., additional, Heitz, Florian, additional, Hildebrandt, Michelle A., additional, Høgdall, Estrid, additional, Høgdall, Claus K., additional, Huntsman, David G., additional, Kar, Siddhartha P., additional, Karlan, Beth Y., additional, Kelemen, Linda E., additional, Kiemeney, Lambertus A., additional, Kjaer, Susanne K., additional, Koushik, Anita, additional, Lambrechts, Diether, additional, Le, Nhu D., additional, Levine, Douglas A., additional, Massuger, Leon F., additional, Matsuo, Keitaro, additional, May, Taymaa, additional, McNeish, Iain A., additional, Menon, Usha, additional, Modugno, Francesmary, additional, Monteiro, Alvaro N., additional, Moorman, Patricia G., additional, Moysich, Kirsten B., additional, Ness, Roberta B., additional, Nevanlinna, Heli, additional, Olsson, Håkan, additional, Onland-Moret, N. Charlotte, additional, Park, Sue K., additional, Paul, James, additional, Pearce, Celeste L., additional, Pejovic, Tanja, additional, Phelan, Catherine M., additional, Pike, Malcolm C., additional, Ramus, Susan J., additional, Riboli, Elio, additional, Rodriguez-Antona, Cristina, additional, Romieu, Isabelle, additional, Sandler, Dale P., additional, Schildkraut, Joellen M., additional, Setiawan, Veronica W., additional, Shan, Kang, additional, Siddiqui, Nadeem, additional, Sieh, Weiva, additional, Stampfer, Meir J., additional, Sutphen, Rebecca, additional, Swerdlow, Anthony J., additional, Szafron, Lukasz M., additional, Teo, Soo Hwang, additional, Tworoger, Shelley S., additional, Tyrer, Jonathan P., additional, Webb, Penelope M., additional, Wentzensen, Nicolas, additional, White, Emily, additional, Willett, Walter C., additional, Wolk, Alicja, additional, Woo, Yin Ling, additional, Wu, Anna H., additional, Yan, Li, additional, Yannoukakos, Drakoulis, additional, Chenevix-Trench, Georgia, additional, Sellers, Thomas A., additional, Pharoah, Paul D.P., additional, Zheng, Wei, additional, and Long, Jirong, additional
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- 2019
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45. Genetic Risk Score Mendelian Randomization Shows that Obesity Measured as Body Mass Index, but not Waist:Hip Ratio, Is Causal for Endometrial Cancer
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Painter, Jodie N., primary, O'Mara, Tracy A., additional, Marquart, Louise, additional, Webb, Penelope M., additional, Attia, John, additional, Medland, Sarah E., additional, Cheng, Timothy, additional, Dennis, Joe, additional, Holliday, Elizabeth G., additional, McEvoy, Mark, additional, Scott, Rodney J., additional, Ahmed, Shahana, additional, Healey, Catherine S., additional, Shah, Mitul, additional, Gorman, Maggie, additional, Martin, Lynn, additional, Hodgson, Shirley V., additional, Beckmann, Matthias W., additional, Ekici, Arif B., additional, Fasching, Peter A., additional, Hein, Alexander, additional, Rübner, Matthias, additional, Czene, Kamila, additional, Darabi, Hatef, additional, Hall, Per, additional, Li, Jingmei, additional, Dörk, Thilo, additional, Dürst, Matthias, additional, Hillemanns, Peter, additional, Runnebaum, Ingo B., additional, Amant, Frederic, additional, Annibali, Daniela, additional, Depreeuw, Jeroen, additional, Lambrechts, Diether, additional, Neven, Patrick, additional, Cunningham, Julie M., additional, Dowdy, Sean C., additional, Goode, Ellen L., additional, Fridley, Brooke L., additional, Winham, Stacey J., additional, Njølstad, Tormund S., additional, Salvesen, Helga B., additional, Trovik, Jone, additional, Werner, Henrica M.J., additional, Ashton, Katie A., additional, Otton, Geoffrey, additional, Proietto, Anthony, additional, Mints, Miriam, additional, Tham, Emma, additional, Bolla, Manjeet K., additional, Michailidou, Kyriaki, additional, Wang, Qin, additional, Tyrer, Jonathan P., additional, Hopper, John L., additional, Peto, Julian, additional, Swerdlow, Anthony J., additional, Burwinkel, Barbara, additional, Brenner, Hermann, additional, Meindl, Alfons, additional, Brauch, Hiltrud, additional, Lindblom, Annika, additional, Chang-Claude, Jenny, additional, Couch, Fergus J., additional, Giles, Graham G., additional, Kristensen, Vessela N., additional, Cox, Angela, additional, Pharoah, Paul D.P., additional, Tomlinson, Ian, additional, Dunning, Alison M., additional, Easton, Douglas F., additional, Thompson, Deborah J., additional, and Spurdle, Amanda B., additional
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- 2016
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46. Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations
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Fehringer, Gordon, primary, Kraft, Peter, additional, Pharoah, Paul D., additional, Eeles, Rosalind A., additional, Chatterjee, Nilanjan, additional, Schumacher, Fredrick R., additional, Schildkraut, Joellen M., additional, Lindström, Sara, additional, Brennan, Paul, additional, Bickeböller, Heike, additional, Houlston, Richard S., additional, Landi, Maria Teresa, additional, Caporaso, Neil, additional, Risch, Angela, additional, Amin Al Olama, Ali, additional, Berndt, Sonja I., additional, Giovannucci, Edward L., additional, Grönberg, Henrik, additional, Kote-Jarai, Zsofia, additional, Ma, Jing, additional, Muir, Kenneth, additional, Stampfer, Meir J., additional, Stevens, Victoria L., additional, Wiklund, Fredrik, additional, Willett, Walter C., additional, Goode, Ellen L., additional, Permuth, Jennifer B., additional, Risch, Harvey A., additional, Reid, Brett M., additional, Bezieau, Stephane, additional, Brenner, Hermann, additional, Chan, Andrew T., additional, Chang-Claude, Jenny, additional, Hudson, Thomas J., additional, Kocarnik, Jonathan K., additional, Newcomb, Polly A., additional, Schoen, Robert E., additional, Slattery, Martha L., additional, White, Emily, additional, Adank, Muriel A., additional, Ahsan, Habibul, additional, Aittomäki, Kristiina, additional, Baglietto, Laura, additional, Blomquist, Carl, additional, Canzian, Federico, additional, Czene, Kamila, additional, dos-Santos-Silva, Isabel, additional, Eliassen, A. Heather, additional, Figueroa, Jonine D., additional, Flesch-Janys, Dieter, additional, Fletcher, Olivia, additional, Garcia-Closas, Montserrat, additional, Gaudet, Mia M., additional, Johnson, Nichola, additional, Hall, Per, additional, Hazra, Aditi, additional, Hein, Rebecca, additional, Hofman, Albert, additional, Hopper, John L., additional, Irwanto, Astrid, additional, Johansson, Mattias, additional, Kaaks, Rudolf, additional, Kibriya, Muhammad G., additional, Lichtner, Peter, additional, Liu, Jianjun, additional, Lund, Eiliv, additional, Makalic, Enes, additional, Meindl, Alfons, additional, Müller-Myhsok, Bertram, additional, Muranen, Taru A., additional, Nevanlinna, Heli, additional, Peeters, Petra H., additional, Peto, Julian, additional, Prentice, Ross L., additional, Rahman, Nazneen, additional, Sanchez, Maria Jose, additional, Schmidt, Daniel F., additional, Schmutzler, Rita K., additional, Southey, Melissa C., additional, Tamimi, Rulla, additional, Travis, Ruth C., additional, Turnbull, Clare, additional, Uitterlinden, Andre G., additional, Wang, Zhaoming, additional, Whittemore, Alice S., additional, Yang, Xiaohong R., additional, Zheng, Wei, additional, Buchanan, Daniel D., additional, Casey, Graham, additional, Conti, David V., additional, Edlund, Christopher K., additional, Gallinger, Steven, additional, Haile, Robert W., additional, Jenkins, Mark, additional, Le Marchand, Loïc, additional, Li, Li, additional, Lindor, Noralene M., additional, Schmit, Stephanie L., additional, Thibodeau, Stephen N., additional, Woods, Michael O., additional, Rafnar, Thorunn, additional, Gudmundsson, Julius, additional, Stacey, Simon N., additional, Stefansson, Kari, additional, Sulem, Patrick, additional, Chen, Y. Ann, additional, Tyrer, Jonathan P., additional, Christiani, David C., additional, Wei, Yongyue, additional, Shen, Hongbing, additional, Hu, Zhibin, additional, Shu, Xiao-Ou, additional, Shiraishi, Kouya, additional, Takahashi, Atsushi, additional, Bossé, Yohan, additional, Obeidat, Ma'en, additional, Nickle, David, additional, Timens, Wim, additional, Freedman, Matthew L., additional, Li, Qiyuan, additional, Seminara, Daniela, additional, Chanock, Stephen J., additional, Gong, Jian, additional, Peters, Ulrike, additional, Gruber, Stephen B., additional, Amos, Christopher I., additional, Sellers, Thomas A., additional, Easton, Douglas F., additional, Hunter, David J., additional, Haiman, Christopher A., additional, Henderson, Brian E., additional, and Hung, Rayjean J., additional
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- 2016
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47. Assessment of Multifactor Gene–Environment Interactions and Ovarian Cancer Risk: Candidate Genes, Obesity, and Hormone-Related Risk Factors
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Usset, Joseph L., primary, Raghavan, Rama, additional, Tyrer, Jonathan P., additional, McGuire, Valerie, additional, Sieh, Weiva, additional, Webb, Penelope, additional, Chang-Claude, Jenny, additional, Rudolph, Anja, additional, Anton-Culver, Hoda, additional, Berchuck, Andrew, additional, Brinton, Louise, additional, Cunningham, Julie M., additional, DeFazio, Anna, additional, Doherty, Jennifer A., additional, Edwards, Robert P., additional, Gayther, Simon A., additional, Gentry-Maharaj, Aleksandra, additional, Goodman, Marc T., additional, Høgdall, Estrid, additional, Jensen, Allan, additional, Johnatty, Sharon E., additional, Kiemeney, Lambertus A., additional, Kjaer, Susanne K., additional, Larson, Melissa C., additional, Lurie, Galina, additional, Massuger, Leon, additional, Menon, Usha, additional, Modugno, Francesmary, additional, Moysich, Kirsten B., additional, Ness, Roberta B., additional, Pike, Malcolm C., additional, Ramus, Susan J., additional, Rossing, Mary Anne, additional, Rothstein, Joseph, additional, Song, Honglin, additional, Thompson, Pamela J., additional, van den Berg, David J., additional, Vierkant, Robert A., additional, Wang-Gohrke, Shan, additional, Wentzensen, Nicolas, additional, Whittemore, Alice S., additional, Wilkens, Lynne R., additional, Wu, Anna H., additional, Yang, Hannah, additional, Pearce, Celeste Leigh, additional, Schildkraut, Joellen M., additional, Pharoah, Paul, additional, Goode, Ellen L., additional, and Fridley, Brooke L., additional
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- 2016
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48. Genetic Risk Score Mendelian Randomization Shows that Obesity Measured as Body Mass Index, but not Waist:Hip Ratio, Is Causal for Endometrial Cancer
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Painter, Jodie N, O'Mara, Tracy A, Marquart, Louise, Webb, Penelope M, Attia, John, Medland, Sarah E, Cheng, Timothy, Dennis, Joe, Holliday, Elizabeth G, McEvoy, Mark, Scott, Rodney J, Ahmed, Shahana, Healey, Catherine S, Shah, Mitul, Gorman, Maggie, Martin, Lynn, Hodgson, Shirley V, Beckmann, Matthias W, Ekici, Arif B, Fasching, Peter A, Hein, Alexander, Rübner, Matthias, Czene, Kamila, Darabi, Hatef, Hall, Per, Li, Jingmei, Dörk, Thilo, Dürst, Matthias, Hillemanns, Peter, Runnebaum, Ingo B, Amant, Frederic, Annibali, Daniela, Depreeuw, Jeroen, Lambrechts, Diether, Neven, Patrick, Cunningham, Julie M, Dowdy, Sean C, Goode, Ellen L, Fridley, Brooke L, Winham, Stacey J, Njølstad, Tormund S, Salvesen, Helga B, Trovik, Jone, Werner, Henrica MJ, Ashton, Katie A, Otton, Geoffrey, Proietto, Anthony, Mints, Miriam, Tham, Emma, Bolla, Manjeet K, Michailidou, Kyriaki, Wang, Qin, Tyrer, Jonathan P, Hopper, John L, Peto, Julian, Swerdlow, Anthony J, Burwinkel, Barbara, Brenner, Hermann, Meindl, Alfons, Brauch, Hiltrud, Lindblom, Annika, Chang-Claude, Jenny, Couch, Fergus J, Giles, Graham G, Kristensen, Vessela N, Cox, Angela, Pharoah, Paul DP, Tomlinson, Ian, Dunning, Alison M, Easton, Douglas F, Thompson, Deborah J, Spurdle, Amanda B, AOCS Group, For RENDOCAS, National Study Of Endometrial Cancer Genetics Group (NSECG), and Australian National Endometrial Cancer Study Group (ANECS)
- Subjects
2. Zero hunger ,Waist-Hip Ratio ,nutritional and metabolic diseases ,Humans ,Female ,Genetic Predisposition to Disease ,Obesity ,Mendelian Randomization Analysis ,Polymorphism, Single Nucleotide ,3. Good health ,Body Mass Index ,Endometrial Neoplasms - Abstract
BACKGROUND: The strongest known risk factor for endometrial cancer is obesity. To determine whether SNPs associated with increased body mass index (BMI) or waist-hip ratio (WHR) are associated with endometrial cancer risk, independent of measured BMI, we investigated relationships between 77 BMI and 47 WHR SNPs and endometrial cancer in 6,609 cases and 37,926 country-matched controls. METHODS: Logistic regression analysis and fixed effects meta-analysis were used to test for associations between endometrial cancer risk and (i) individual BMI or WHR SNPs, (ii) a combined weighted genetic risk score (wGRS) for BMI or WHR. Causality of BMI for endometrial cancer was assessed using Mendelian randomization, with BMIwGRS as instrumental variable. RESULTS: The BMIwGRS was significantly associated with endometrial cancer risk (P = 3.4 × 10-17). Scaling the effect of the BMIwGRS on endometrial cancer risk by its effect on BMI, the endometrial cancer OR per 5 kg/m2 of genetically predicted BMI was 2.06 [95% confidence interval (CI), 1.89-2.21], larger than the observed effect of BMI on endometrial cancer risk (OR = 1.55; 95% CI, 1.44-1.68, per 5 kg/m2). The association attenuated but remained significant after adjusting for BMI (OR = 1.22; 95% CI, 1.10-1.39; P = 5.3 × 10-4). There was evidence of directional pleiotropy (P = 1.5 × 10-4). BMI SNP rs2075650 was associated with endometrial cancer at study-wide significance (P < 4.0 × 10-4), independent of BMI. Endometrial cancer was not significantly associated with individual WHR SNPs or the WHRwGRS. CONCLUSIONS: BMI, but not WHR, is causally associated with endometrial cancer risk, with evidence that some BMI-associated SNPs alter endometrial cancer risk via mechanisms other than measurable BMI. IMPACT: The causal association between BMI SNPs and endometrial cancer has possible implications for endometrial cancer risk modeling. Cancer Epidemiol Biomarkers Prev; 25(11); 1503-10. ©2016 AACR.
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