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Start Over Author "LUO Ping" Publisher american association for cancer research (aacr)
43 results on '"LUO Ping"'

1. Early Changes in Tumor-Naive Cell-Free Methylomes and Fragmentomes Predict Outcomes in Pembrolizumab-Treated Solid Tumors

Author

Stutheit-Zhao, Eric Y., primary, Sanz-Garcia, Enrique, additional, Liu, Zhihui (Amy), additional, Wong, Derek, additional, Marsh, Kayla, additional, Abdul Razak, Albiruni R., additional, Spreafico, Anna, additional, Bedard, Philippe L., additional, Hansen, Aaron R., additional, Lheureux, Stephanie, additional, Torti, Dax, additional, Lam, Bernard, additional, Yang, Shih Yu Cindy, additional, Burgener, Justin, additional, Luo, Ping, additional, Zeng, Yong, additional, Cheng, Nicholas, additional, Awadalla, Philip, additional, Bratman, Scott V., additional, Ohashi, Pamela S., additional, Pugh, Trevor J., additional, and Siu, Lillian L., additional

Published
2024
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2. Figure S3 from Early Cancer Detection in Li–Fraumeni Syndrome with Cell-Free DNA

Author

Wong, Derek, primary, Luo, Ping, primary, Oldfield, Leslie E., primary, Gong, Haifan, primary, Brunga, Ledia, primary, Rabinowicz, Ron, primary, Subasri, Vallijah, primary, Chan, Clarissa, primary, Downs, Tiana, primary, Farncombe, Kirsten M., primary, Luu, Beatrice, primary, Norman, Maia, primary, Sobotka, Julia A., primary, Uju, Precious, primary, Eagles, Jenna, primary, Pedersen, Stephanie, primary, Wellum, Johanna, primary, Danesh, Arnavaz, primary, Prokopec, Stephenie D., primary, Stutheit-Zhao, Eric Y., primary, Znassi, Nadia, primary, Heisler, Lawrence E., primary, Jovelin, Richard, primary, Lam, Bernard, primary, Lujan Toro, Beatriz E., primary, Marsh, Kayla, primary, Sundaravadanam, Yogi, primary, Torti, Dax, primary, Man, Carina, primary, Goldenberg, Anna, primary, Xu, Wei, primary, Veit-Haibach, Patrick, primary, Doria, Andrea S., primary, Malkin, David, primary, Kim, Raymond H., primary, and Pugh, Trevor J., primary

Published
2024
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3. Early Cancer Detection in Li-Fraumeni Syndrome with Cell-Free DNA

Author

Wong, Derek, primary, Luo, Ping, additional, Oldfield , Leslie E., additional, Gong, Haifan, additional, Brunga, Ledia, additional, Rabinowicz, Ron, additional, Subasri, Vallijah, additional, Chan, Clarissa, additional, Downs, Tiana, additional, Farncombe, Kirsten M., additional, Luu, Beatrice, additional, Norman, Maia, additional, Sobotka, Julia A., additional, Uju, Precious, additional, Eagles, Jenna, additional, Pedersen, Stephanie, additional, Wellum, Johanna, additional, Danesh, Arnavaz, additional, Prokopec, Stephenie D., additional, Stutheit-Zhao, Eric Y., additional, Znassi, Nadia, additional, Heisler, Lawrence E., additional, Jovelin, Richard, additional, Lam, Bernard, additional, Lujan Toro, Beatriz E., additional, Marsh, Kayla, additional, Sundaravadanam, Yogi, additional, Torti, Dax, additional, Man, Carina, additional, Goldenberg, Anna, additional, Xu, Wei, additional, Veit-Haibach, Patrick, additional, Doria, Andrea S., additional, Malkin, David, additional, Kim, Raymond H., additional, and Pugh, Trevor J., additional

Published
2023
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4. Supplementary Data S3 from Multiple Germline Events Contribute to Cancer Development in Patients with Li-Fraumeni Syndrome

Author

Subasri, Vallijah, primary, Light, Nicholas, primary, Kanwar, Nisha, primary, Brzezinski, Jack, primary, Luo, Ping, primary, Hansford, Jordan R., primary, Cairney, Elizabeth, primary, Portwine, Carol, primary, Elser, Christine, primary, Finlay, Jonathan L., primary, Nichols, Kim E., primary, Alon, Noa, primary, Brunga, Ledia, primary, Anson, Jo, primary, Kohlmann, Wendy, primary, de Andrade, Kelvin C., primary, Khincha, Payal P., primary, Savage, Sharon A., primary, Schiffman, Joshua D., primary, Weksberg, Rosanna, primary, Pugh, Trevor J., primary, Villani, Anita, primary, Shlien, Adam, primary, Goldenberg, Anna, primary, and Malkin, David, primary

Published
2023
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5. FIGURE 2 from Multiple Germline Events Contribute to Cancer Development in Patients with Li-Fraumeni Syndrome

Author

Subasri, Vallijah, primary, Light, Nicholas, primary, Kanwar, Nisha, primary, Brzezinski, Jack, primary, Luo, Ping, primary, Hansford, Jordan R., primary, Cairney, Elizabeth, primary, Portwine, Carol, primary, Elser, Christine, primary, Finlay, Jonathan L., primary, Nichols, Kim E., primary, Alon, Noa, primary, Brunga, Ledia, primary, Anson, Jo, primary, Kohlmann, Wendy, primary, de Andrade, Kelvin C., primary, Khincha, Payal P., primary, Savage, Sharon A., primary, Schiffman, Joshua D., primary, Weksberg, Rosanna, primary, Pugh, Trevor J., primary, Villani, Anita, primary, Shlien, Adam, primary, Goldenberg, Anna, primary, and Malkin, David, primary

Published
2023
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6. FIGURE 3 from Multiple Germline Events Contribute to Cancer Development in Patients with Li-Fraumeni Syndrome

Author

Subasri, Vallijah, primary, Light, Nicholas, primary, Kanwar, Nisha, primary, Brzezinski, Jack, primary, Luo, Ping, primary, Hansford, Jordan R., primary, Cairney, Elizabeth, primary, Portwine, Carol, primary, Elser, Christine, primary, Finlay, Jonathan L., primary, Nichols, Kim E., primary, Alon, Noa, primary, Brunga, Ledia, primary, Anson, Jo, primary, Kohlmann, Wendy, primary, de Andrade, Kelvin C., primary, Khincha, Payal P., primary, Savage, Sharon A., primary, Schiffman, Joshua D., primary, Weksberg, Rosanna, primary, Pugh, Trevor J., primary, Villani, Anita, primary, Shlien, Adam, primary, Goldenberg, Anna, primary, and Malkin, David, primary

Published
2023
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7. TABLE 1 from Multiple Germline Events Contribute to Cancer Development in Patients with Li-Fraumeni Syndrome

Author

Subasri, Vallijah, primary, Light, Nicholas, primary, Kanwar, Nisha, primary, Brzezinski, Jack, primary, Luo, Ping, primary, Hansford, Jordan R., primary, Cairney, Elizabeth, primary, Portwine, Carol, primary, Elser, Christine, primary, Finlay, Jonathan L., primary, Nichols, Kim E., primary, Alon, Noa, primary, Brunga, Ledia, primary, Anson, Jo, primary, Kohlmann, Wendy, primary, de Andrade, Kelvin C., primary, Khincha, Payal P., primary, Savage, Sharon A., primary, Schiffman, Joshua D., primary, Weksberg, Rosanna, primary, Pugh, Trevor J., primary, Villani, Anita, primary, Shlien, Adam, primary, Goldenberg, Anna, primary, and Malkin, David, primary

Published
2023
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8. TABLE 2 from Multiple Germline Events Contribute to Cancer Development in Patients with Li-Fraumeni Syndrome

Author

Subasri, Vallijah, primary, Light, Nicholas, primary, Kanwar, Nisha, primary, Brzezinski, Jack, primary, Luo, Ping, primary, Hansford, Jordan R., primary, Cairney, Elizabeth, primary, Portwine, Carol, primary, Elser, Christine, primary, Finlay, Jonathan L., primary, Nichols, Kim E., primary, Alon, Noa, primary, Brunga, Ledia, primary, Anson, Jo, primary, Kohlmann, Wendy, primary, de Andrade, Kelvin C., primary, Khincha, Payal P., primary, Savage, Sharon A., primary, Schiffman, Joshua D., primary, Weksberg, Rosanna, primary, Pugh, Trevor J., primary, Villani, Anita, primary, Shlien, Adam, primary, Goldenberg, Anna, primary, and Malkin, David, primary

Published
2023
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9. FIGURE 1 from Multiple Germline Events Contribute to Cancer Development in Patients with Li-Fraumeni Syndrome

Author

Subasri, Vallijah, primary, Light, Nicholas, primary, Kanwar, Nisha, primary, Brzezinski, Jack, primary, Luo, Ping, primary, Hansford, Jordan R., primary, Cairney, Elizabeth, primary, Portwine, Carol, primary, Elser, Christine, primary, Finlay, Jonathan L., primary, Nichols, Kim E., primary, Alon, Noa, primary, Brunga, Ledia, primary, Anson, Jo, primary, Kohlmann, Wendy, primary, de Andrade, Kelvin C., primary, Khincha, Payal P., primary, Savage, Sharon A., primary, Schiffman, Joshua D., primary, Weksberg, Rosanna, primary, Pugh, Trevor J., primary, Villani, Anita, primary, Shlien, Adam, primary, Goldenberg, Anna, primary, and Malkin, David, primary

Published
2023
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10. FIGURE 5 from Multiple Germline Events Contribute to Cancer Development in Patients with Li-Fraumeni Syndrome

Author

Subasri, Vallijah, primary, Light, Nicholas, primary, Kanwar, Nisha, primary, Brzezinski, Jack, primary, Luo, Ping, primary, Hansford, Jordan R., primary, Cairney, Elizabeth, primary, Portwine, Carol, primary, Elser, Christine, primary, Finlay, Jonathan L., primary, Nichols, Kim E., primary, Alon, Noa, primary, Brunga, Ledia, primary, Anson, Jo, primary, Kohlmann, Wendy, primary, de Andrade, Kelvin C., primary, Khincha, Payal P., primary, Savage, Sharon A., primary, Schiffman, Joshua D., primary, Weksberg, Rosanna, primary, Pugh, Trevor J., primary, Villani, Anita, primary, Shlien, Adam, primary, Goldenberg, Anna, primary, and Malkin, David, primary

Published
2023
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11. FIGURE 4 from Multiple Germline Events Contribute to Cancer Development in Patients with Li-Fraumeni Syndrome

Author

Subasri, Vallijah, primary, Light, Nicholas, primary, Kanwar, Nisha, primary, Brzezinski, Jack, primary, Luo, Ping, primary, Hansford, Jordan R., primary, Cairney, Elizabeth, primary, Portwine, Carol, primary, Elser, Christine, primary, Finlay, Jonathan L., primary, Nichols, Kim E., primary, Alon, Noa, primary, Brunga, Ledia, primary, Anson, Jo, primary, Kohlmann, Wendy, primary, de Andrade, Kelvin C., primary, Khincha, Payal P., primary, Savage, Sharon A., primary, Schiffman, Joshua D., primary, Weksberg, Rosanna, primary, Pugh, Trevor J., primary, Villani, Anita, primary, Shlien, Adam, primary, Goldenberg, Anna, primary, and Malkin, David, primary

Published
2023
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12. Supplementary Figures S1-S12 from Multiple Germline Events Contribute to Cancer Development in Patients with Li-Fraumeni Syndrome

Author

Subasri, Vallijah, primary, Light, Nicholas, primary, Kanwar, Nisha, primary, Brzezinski, Jack, primary, Luo, Ping, primary, Hansford, Jordan R., primary, Cairney, Elizabeth, primary, Portwine, Carol, primary, Elser, Christine, primary, Finlay, Jonathan L., primary, Nichols, Kim E., primary, Alon, Noa, primary, Brunga, Ledia, primary, Anson, Jo, primary, Kohlmann, Wendy, primary, de Andrade, Kelvin C., primary, Khincha, Payal P., primary, Savage, Sharon A., primary, Schiffman, Joshua D., primary, Weksberg, Rosanna, primary, Pugh, Trevor J., primary, Villani, Anita, primary, Shlien, Adam, primary, Goldenberg, Anna, primary, and Malkin, David, primary

Published
2023
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13. Data from Multiple Germline Events Contribute to Cancer Development in Patients with Li-Fraumeni Syndrome

Author

Subasri, Vallijah, primary, Light, Nicholas, primary, Kanwar, Nisha, primary, Brzezinski, Jack, primary, Luo, Ping, primary, Hansford, Jordan R., primary, Cairney, Elizabeth, primary, Portwine, Carol, primary, Elser, Christine, primary, Finlay, Jonathan L., primary, Nichols, Kim E., primary, Alon, Noa, primary, Brunga, Ledia, primary, Anson, Jo, primary, Kohlmann, Wendy, primary, de Andrade, Kelvin C., primary, Khincha, Payal P., primary, Savage, Sharon A., primary, Schiffman, Joshua D., primary, Weksberg, Rosanna, primary, Pugh, Trevor J., primary, Villani, Anita, primary, Shlien, Adam, primary, Goldenberg, Anna, primary, and Malkin, David, primary

Published
2023
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14. Table TS6 from Integrated, Longitudinal Analysis of Cell-free DNA in Uveal Melanoma

Author

Wong, Derek, primary, Luo, Ping, primary, Znassi, Nadia, primary, Arteaga, Diana P., primary, Gray, Diana, primary, Danesh, Arnavaz, primary, Han, Ming, primary, Zhao, Eric Y., primary, Pedersen, Stephanie, primary, Prokopec, Stephenie, primary, Sundaravadanam, Yogi, primary, Torti, Dax, primary, Marsh, Kayla, primary, Keshavarzi, Sareh, primary, Xu, Wei, primary, Krema, Hatem, primary, Joshua, Anthony M., primary, Butler, Marcus O., primary, and Pugh, Trevor J., primary

Published
2023
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15. Figure S1 from Integrated, Longitudinal Analysis of Cell-free DNA in Uveal Melanoma

Author

Wong, Derek, primary, Luo, Ping, primary, Znassi, Nadia, primary, Arteaga, Diana P., primary, Gray, Diana, primary, Danesh, Arnavaz, primary, Han, Ming, primary, Zhao, Eric Y., primary, Pedersen, Stephanie, primary, Prokopec, Stephenie, primary, Sundaravadanam, Yogi, primary, Torti, Dax, primary, Marsh, Kayla, primary, Keshavarzi, Sareh, primary, Xu, Wei, primary, Krema, Hatem, primary, Joshua, Anthony M., primary, Butler, Marcus O., primary, and Pugh, Trevor J., primary

Published
2023
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16. Data from Integrated, Longitudinal Analysis of Cell-free DNA in Uveal Melanoma

Author

Wong, Derek, primary, Luo, Ping, primary, Znassi, Nadia, primary, Arteaga, Diana P., primary, Gray, Diana, primary, Danesh, Arnavaz, primary, Han, Ming, primary, Zhao, Eric Y., primary, Pedersen, Stephanie, primary, Prokopec, Stephenie, primary, Sundaravadanam, Yogi, primary, Torti, Dax, primary, Marsh, Kayla, primary, Keshavarzi, Sareh, primary, Xu, Wei, primary, Krema, Hatem, primary, Joshua, Anthony M., primary, Butler, Marcus O., primary, and Pugh, Trevor J., primary

Published
2023
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17. Data from L-Plastin Promotes Gastric Cancer Growth and Metastasis in a Helicobacter pylori cagA-ERK-SP1–Dependent Manner

Author

Teng, Yong-Sheng, primary, Chen, Wan-Yan, primary, Yan, Zong-Bao, primary, Lv, Yi-Pin, primary, Liu, Yu-Gang, primary, Mao, Fang-Yuan, primary, Zhao, Yong-Liang, primary, Peng, Liu-Sheng, primary, Cheng, Ping, primary, Duan, Mu-Bing, primary, Chen, Weisan, primary, Wang, Yu, primary, Luo, Ping, primary, Zou, Quan-Ming, primary, Chen, Jun, primary, and Zhuang, Yuan, primary

Published
2023
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18. Supplementary Figures 1-6 from L-Plastin Promotes Gastric Cancer Growth and Metastasis in a Helicobacter pylori cagA-ERK-SP1–Dependent Manner

Author

Teng, Yong-Sheng, primary, Chen, Wan-Yan, primary, Yan, Zong-Bao, primary, Lv, Yi-Pin, primary, Liu, Yu-Gang, primary, Mao, Fang-Yuan, primary, Zhao, Yong-Liang, primary, Peng, Liu-Sheng, primary, Cheng, Ping, primary, Duan, Mu-Bing, primary, Chen, Weisan, primary, Wang, Yu, primary, Luo, Ping, primary, Zou, Quan-Ming, primary, Chen, Jun, primary, and Zhuang, Yuan, primary

Published
2023
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19. Supplementary Tables 1 and 2 from L-Plastin Promotes Gastric Cancer Growth and Metastasis in a Helicobacter pylori cagA-ERK-SP1–Dependent Manner

Author

Teng, Yong-Sheng, primary, Chen, Wan-Yan, primary, Yan, Zong-Bao, primary, Lv, Yi-Pin, primary, Liu, Yu-Gang, primary, Mao, Fang-Yuan, primary, Zhao, Yong-Liang, primary, Peng, Liu-Sheng, primary, Cheng, Ping, primary, Duan, Mu-Bing, primary, Chen, Weisan, primary, Wang, Yu, primary, Luo, Ping, primary, Zou, Quan-Ming, primary, Chen, Jun, primary, and Zhuang, Yuan, primary

Published
2023
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20. Multiple germline events contribute to cancer development in patients with Li-Fraumeni syndrome

Author

Subasri, Vallijah, primary, Light, Nicholas, additional, Kanwar, Nisha, additional, Brzezinski, Jack, additional, Luo, Ping, additional, Hansford, Jordan R, additional, Cairney, Elizabeth, additional, Portwine, Carol, additional, Elser, Christine, additional, Finlay, Jonathan L., additional, Nichols, Kim E., additional, Alon, Noa, additional, Brunga, Ledia, additional, Anson, Jo, additional, Kohlmann, Wendy, additional, de Andrade, Kelvin C., additional, Khincha, Payal P., additional, Savage, Sharon A., additional, Schiffman, Joshua D, additional, Weksberg, Rosanna, additional, Pugh, Trevor J., additional, Villani, Anita, additional, Shlien, Adam, additional, Goldenberg, Anna, additional, and Malkin, David, additional

Published
2023
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21. Data from Hypoxia Drives Breast Tumor Malignancy through a TET–TNFα–p38–MAPK Signaling Axis

Author

Wu, Min-Zu, primary, Chen, Su-Feng, primary, Nieh, Shin, primary, Benner, Christopher, primary, Ger, Luo-Ping, primary, Jan, Chia-Ing, primary, Ma, Li, primary, Chen, Chien-Hung, primary, Hishida, Tomoaki, primary, Chang, Hong-Tai, primary, Lin, Yaoh-Shiang, primary, Montserrat, Nuria, primary, Gascon, Pedro, primary, Sancho-Martinez, Ignacio, primary, and Izpisua Belmonte, Juan Carlos, primary

Published
2023
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22. Table S2 from Hypoxia Drives Breast Tumor Malignancy through a TET–TNFα–p38–MAPK Signaling Axis

Author

Wu, Min-Zu, primary, Chen, Su-Feng, primary, Nieh, Shin, primary, Benner, Christopher, primary, Ger, Luo-Ping, primary, Jan, Chia-Ing, primary, Ma, Li, primary, Chen, Chien-Hung, primary, Hishida, Tomoaki, primary, Chang, Hong-Tai, primary, Lin, Yaoh-Shiang, primary, Montserrat, Nuria, primary, Gascon, Pedro, primary, Sancho-Martinez, Ignacio, primary, and Izpisua Belmonte, Juan Carlos, primary

Published
2023
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23. Supplementary Figure 2 from Carboxyl-Terminal Modulator Protein Positively Regulates Akt Phosphorylation and Acts as an Oncogenic Driver in Breast Cancer

Author

Liu, Yu-Peng, primary, Liao, Wen-Chi, primary, Ger, Luo-Ping, primary, Chen, Jiun-Chin, primary, Hsu, Tai-I, primary, Lee, Yu-Cheng, primary, Chang, Hong-Tai, primary, Chen, Yu-Chia, primary, Jan, Yi-Hua, primary, Lee, Kuen-Haur, primary, Zeng, Yu-Hao, primary, Hsiao, Michael, primary, and Lu, Pei-Jung, primary

Published
2023
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24. Data from Carboxyl-Terminal Modulator Protein Positively Regulates Akt Phosphorylation and Acts as an Oncogenic Driver in Breast Cancer

Author

Liu, Yu-Peng, primary, Liao, Wen-Chi, primary, Ger, Luo-Ping, primary, Chen, Jiun-Chin, primary, Hsu, Tai-I, primary, Lee, Yu-Cheng, primary, Chang, Hong-Tai, primary, Chen, Yu-Chia, primary, Jan, Yi-Hua, primary, Lee, Kuen-Haur, primary, Zeng, Yu-Hao, primary, Hsiao, Michael, primary, and Lu, Pei-Jung, primary

Published
2023
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25. Supplementary Figure 4 from Carboxyl-Terminal Modulator Protein Positively Regulates Akt Phosphorylation and Acts as an Oncogenic Driver in Breast Cancer

Author

Liu, Yu-Peng, primary, Liao, Wen-Chi, primary, Ger, Luo-Ping, primary, Chen, Jiun-Chin, primary, Hsu, Tai-I, primary, Lee, Yu-Cheng, primary, Chang, Hong-Tai, primary, Chen, Yu-Chia, primary, Jan, Yi-Hua, primary, Lee, Kuen-Haur, primary, Zeng, Yu-Hao, primary, Hsiao, Michael, primary, and Lu, Pei-Jung, primary

Published
2023
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26. Supplementary Figures S1-19 and legends from Hypoxia Drives Breast Tumor Malignancy through a TET–TNFα–p38–MAPK Signaling Axis

Author

Wu, Min-Zu, primary, Chen, Su-Feng, primary, Nieh, Shin, primary, Benner, Christopher, primary, Ger, Luo-Ping, primary, Jan, Chia-Ing, primary, Ma, Li, primary, Chen, Chien-Hung, primary, Hishida, Tomoaki, primary, Chang, Hong-Tai, primary, Lin, Yaoh-Shiang, primary, Montserrat, Nuria, primary, Gascon, Pedro, primary, Sancho-Martinez, Ignacio, primary, and Izpisua Belmonte, Juan Carlos, primary

Published
2023
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27. Supplementary Figure 3 from Carboxyl-Terminal Modulator Protein Positively Regulates Akt Phosphorylation and Acts as an Oncogenic Driver in Breast Cancer

Author

Liu, Yu-Peng, primary, Liao, Wen-Chi, primary, Ger, Luo-Ping, primary, Chen, Jiun-Chin, primary, Hsu, Tai-I, primary, Lee, Yu-Cheng, primary, Chang, Hong-Tai, primary, Chen, Yu-Chia, primary, Jan, Yi-Hua, primary, Lee, Kuen-Haur, primary, Zeng, Yu-Hao, primary, Hsiao, Michael, primary, and Lu, Pei-Jung, primary

Published
2023
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28. Supplementary Table 1 from Carboxyl-Terminal Modulator Protein Positively Regulates Akt Phosphorylation and Acts as an Oncogenic Driver in Breast Cancer

Author

Liu, Yu-Peng, primary, Liao, Wen-Chi, primary, Ger, Luo-Ping, primary, Chen, Jiun-Chin, primary, Hsu, Tai-I, primary, Lee, Yu-Cheng, primary, Chang, Hong-Tai, primary, Chen, Yu-Chia, primary, Jan, Yi-Hua, primary, Lee, Kuen-Haur, primary, Zeng, Yu-Hao, primary, Hsiao, Michael, primary, and Lu, Pei-Jung, primary

Published
2023
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29. Supplementary Table 2 from Carboxyl-Terminal Modulator Protein Positively Regulates Akt Phosphorylation and Acts as an Oncogenic Driver in Breast Cancer

Author

Liu, Yu-Peng, primary, Liao, Wen-Chi, primary, Ger, Luo-Ping, primary, Chen, Jiun-Chin, primary, Hsu, Tai-I, primary, Lee, Yu-Cheng, primary, Chang, Hong-Tai, primary, Chen, Yu-Chia, primary, Jan, Yi-Hua, primary, Lee, Kuen-Haur, primary, Zeng, Yu-Hao, primary, Hsiao, Michael, primary, and Lu, Pei-Jung, primary

Published
2023
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30. Integrated, Longitudinal Analysis of Cell-Free DNA in Uveal Melanoma

Author

Wong, Derek, primary, Luo, Ping, additional, Znassi, Nadia, additional, Arteaga, Diana P., additional, Gray, Diana, additional, Danesh, Arnavaz, additional, Han, Ming, additional, Zhao, Eric Y., additional, Pedersen, Stephanie, additional, Prokopec, Stephenie, additional, Sundaravadanam, Yogi, additional, Torti, Dax, additional, Marsh, Kayla, additional, Keshavarzi, Sareh, additional, Xu, Wei, additional, Krema, Hatem, additional, Joshua, Anthony M, additional, Butler, Marcus O., additional, and Pugh, Trevor J., additional

Published
2023
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34. Supplementary Figure 3 from Carboxyl-Terminal Modulator Protein Positively Regulates Akt Phosphorylation and Acts as an Oncogenic Driver in Breast Cancer

Author

Pei-Jung Lu, Michael Hsiao, Yu-Hao Zeng, Kuen-Haur Lee, Yi-Hua Jan, Yu-Chia Chen, Hong-Tai Chang, Yu-Cheng Lee, Tai-I Hsu, Jiun-Chin Chen, Luo-Ping Ger, Wen-Chi Liao, and Yu-Peng Liu

Abstract

PDF file, 187K, The N-terminal domain, 1-64 a.a., of CTMP is required, but not sufficient, to induce Akt phosphorylation, colony formation and cell proliferation.

Published
2023

35. Supplementary Table 2 from Carboxyl-Terminal Modulator Protein Positively Regulates Akt Phosphorylation and Acts as an Oncogenic Driver in Breast Cancer

Author

Pei-Jung Lu, Michael Hsiao, Yu-Hao Zeng, Kuen-Haur Lee, Yi-Hua Jan, Yu-Chia Chen, Hong-Tai Chang, Yu-Cheng Lee, Tai-I Hsu, Jiun-Chin Chen, Luo-Ping Ger, Wen-Chi Liao, and Yu-Peng Liu

Abstract

PDF file, 63K, Association of CTMP expression with prognosis of patients with different cancer type in 4 cohorts from Prognoscan database.

Published
2023

38. Supplementary Figures S1-19 and legends from Hypoxia Drives Breast Tumor Malignancy through a TET–TNFα–p38–MAPK Signaling Axis

Author

Juan Carlos Izpisua Belmonte, Ignacio Sancho-Martinez, Pedro Gascon, Nuria Montserrat, Yaoh-Shiang Lin, Hong-Tai Chang, Tomoaki Hishida, Chien-Hung Chen, Li Ma, Chia-Ing Jan, Luo-Ping Ger, Christopher Benner, Shin Nieh, Su-Feng Chen, and Min-Zu Wu

Abstract

Supplementary Figures S1-19 and legends. Figure S1: Overexpression of HIF-1α enhances BTIC characteristics. Figure S2: Characterizations of isolated BTICs by different parameters. Figure S3: The expression of TET1 and TET3 is upregulated by hypoxia. Figure S4: HIF-1α binding to TET1 and TET3 gene promoter in HIF-1α overexpressing cells. Figure S5: Knockdown of TET diminishes hypoxia induced activation of stemness related genes in breast cancer cell lines. Figure S6: Knockdown of TET1/3 represses tumorigenicity of isolated BTICs in vivo. Figure S7: Isotype control for IHC analysis. Figure S8: Gene specific changes in 5hmC level and TET proteins binding in hypoxic, HIF-1α overexpressing cells and isolated BTICs. Figure S9: Starvation is unable to affect the levels of 5hmC on the genome regions of TNFα gene and TNFα gene expression. Figure S10: TET proteins are essential for hypoxia activated TNFα-p38-MAPK signaling. Figure S11: TET proteins are required for hypoxia-induced 5hmC change on the genome regions of the TNFα gene. Figure S12: The enzymatic activity of TET proteins is required for establishing 5hmC signature upon hypoxia. Figure S13: The enzymatic activity of TET proteins is required for activation of TNFα-p38-MAPK signaling upon hypoxia. Figure S14: Protein-protein interaction between TET1 and TET3 in hypoxic cells and isolated BTICs. Figure S15: Co-occupancy of TET1 and TET3 on genome regions of the TNFα gene. Figure S16: Suppression of p38-MAPK signaling reduces BTIC properties. Figure S17: Certain downstream targets of TNFα-p38-MAPK signaling are regulated by hypoxia/TET. Figure S18: The levels of 5hmC and the bindings of TET proteins at pluripotent loci upon hypoxia. Figure S19: The landscape for 5hmC level and TET proteins binding on pluripotent loci upon hypoxia.

Published
2023

39. L-Plastin Promotes Gastric Cancer Growth and Metastasis in a Helicobacter pylori cagA-ERK-SP1–Dependent Manner

Author

Teng, Yong-Sheng, primary, Chen, Wan-Yan, additional, Yan, Zong-Bao, additional, Lv, Yi-Pin, additional, Liu, Yu-Gang, additional, Mao, Fang-Yuan, additional, Zhao, Yong-Liang, additional, Peng, Liu-Sheng, additional, Cheng, Ping, additional, Duan, Mu-Bing, additional, Chen, Weisan, additional, Wang, Yu, additional, Luo, Ping, additional, Zou, Quan-Ming, additional, Chen, Jun, additional, and Zhuang, Yuan, additional

Published
2021
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40. Carboxyl-Terminal Modulator Protein Positively Regulates Akt Phosphorylation and Acts as an Oncogenic Driver in Breast Cancer

Author

Tai I. Hsu, Yu Cheng Lee, Wen Chi Liao, Luo Ping Ger, Yu Hao Zeng, Yu Peng Liu, Michael Hsiao, Hong Tai Chang, Yi Hua Jan, Kuen Haur Lee, Jiun Chin Chen, Yu Chia Chen, and Pei Jung Lu

Subjects
Cancer Research, Mice, Nude, Breast Neoplasms, Cell Growth Processes, Transfection, Bioinformatics, medicine.disease_cause, Mice, Breast cancer, Animals, Humans, Medicine, Gene silencing, Phosphorylation, Protein kinase B, Adaptor Proteins, Signal Transducing, business.industry, Membrane Proteins, medicine.disease, Immunohistochemistry, Neoplasm Proteins, Oncology, Tissue Array Analysis, Cancer cell, MCF-7 Cells, Cancer research, Female, Ectopic expression, Thiolester Hydrolases, Signal transduction, business, Carcinogenesis, Microtubule-Associated Proteins, Proto-Oncogene Proteins c-akt, Signal Transduction
Abstract

Akt activation has been implicated broadly in tumorigenesis, but the basis for its dysregulation in cancer cells is incompletely understood. In this study, we sought to clarify a regulatory role for the Akt-binding carboxy-terminal modulator protein (CTMP), which has been controversial. In evaluating CTMP expression in paired normal–tumor specimens of 198 patients with breast cancer, we found that CTMP was upregulated in breast tumors, where it was associated with poor patient survival. Notably, CTMP expression also correlated positively with Akt phosphorylation in breast cancer clinical specimens and cell lines. Furthermore, ectopic expression of CTMP promoted cell proliferation and enhanced the tumorigenic properties of estrogen-dependent breast cancer cells. This effect was correlated with increased sensitivity to insulin-induced Akt phosphorylation, which is mediated primarily by the phosphoinositide 3-kinase–Akt pathway. In contrast, short hairpin RNA-mediated silencing of endogenous CTMP decreased the proliferation of estrogen-dependent or estrogen-independent breast cancer cells. Mechanistic investigations defined the N-terminal domain of CTMP at amino acids 1 to 64 as responsible for Akt binding. Taken together, our results firmly corroborate the concept that CTMP promotes Akt phosphorylation and functions as an oncogenic molecule in breast cancer. Cancer Res; 73(20); 6194–205. ©2013 AACR.

Published
2013

41. Hypoxia Drives Breast Tumor Malignancy through a TET–TNFα–p38–MAPK Signaling Axis

Author

Wu, Min-Zu, primary, Chen, Su-Feng, additional, Nieh, Shin, additional, Benner, Christopher, additional, Ger, Luo-Ping, additional, Jan, Chia-Ing, additional, Ma, Li, additional, Chen, Chien-Hung, additional, Hishida, Tomoaki, additional, Chang, Hong-Tai, additional, Lin, Yaoh-Shiang, additional, Montserrat, Nuria, additional, Gascon, Pedro, additional, Sancho-Martinez, Ignacio, additional, and Izpisua Belmonte, Juan Carlos, additional

Published
2015
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42. Carboxyl-Terminal Modulator Protein Positively Regulates Akt Phosphorylation and Acts as an Oncogenic Driver in Breast Cancer

Author

Liu, Yu-Peng, primary, Liao, Wen-Chi, additional, Ger, Luo-Ping, additional, Chen, Jiun-Chin, additional, Hsu, Tai-I, additional, Lee, Yu-Cheng, additional, Chang, Hong-Tai, additional, Chen, Yu-Chia, additional, Jan, Yi-Hua, additional, Lee, Kuen-Haur, additional, Zeng, Yu-Hao, additional, Hsiao, Michael, additional, and Lu, Pei-Jung, additional

Published
2013
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