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Start Over Author "Harris, Holly" Publisher american association for cancer research (aacr)
50 results on '"Harris, Holly"'

1. Concurrent RB1 Loss and BRCA-Deficiency Predicts Enhanced Immunological Response and Long-Term Survival in Tubo-Ovarian High-Grade Serous Carcinoma

Author

Saner, Flurina A. M., primary, Takahashi, Kazuaki, additional, Budden, Timothy, additional, Pandey, Ahwan, additional, Ariyaratne, Dinuka, additional, Zwimpfer, Tibor A., additional, Meagher, Nicola S., additional, Fereday, Sian, additional, Twomey, Laura, additional, Pishas, Kathleen I., additional, Hoang, Therese, additional, Bolithon, Adelyn, additional, Traficante, Nadia, additional, Alsop, Kathryn, additional, Christie, Elizabeth L., additional, Kang, Eun-Young, additional, Nelson, Gregg S., additional, Ghatage, Prafull, additional, Lee, Cheng-Han, additional, Riggan, Marjorie J., additional, Alsop, Jennifer, additional, Beckmann, Matthias W., additional, Boros, Jessica, additional, Brand, Alison H., additional, Brooks-Wilson, Angela, additional, Carney, Michael E., additional, Coulson, Penny, additional, Courtney-Brooks, Madeleine, additional, Cushing-Haugen, Kara L., additional, Cybulski, Cezary, additional, El-Bahrawy, Mona, additional, Elishaev, Esther, additional, Erber, Ramona, additional, Gayther, Simon A., additional, Gentry-Maharaj, Aleksandra, additional, Gilks, C. Blake, additional, Harnett, Paul R., additional, Harris, Holly R., additional, Hartmann, Arndt, additional, Hein, Alexander, additional, Hendley, Joy, additional, Hernandez, Brenda Y., additional, Jakubowska, Anna, additional, Jimenez-Linan, Mercedes, additional, Jones, Michael E., additional, Kaufmann, Scott H., additional, Kennedy, Catherine J., additional, Kluz, Tomasz, additional, Koziak, Jennifer M., additional, Kristjansdottir, Björg, additional, Le, Nhu D., additional, Lener, Marcin, additional, Lester, Jenny, additional, Lubiński, Jan, additional, Mateoiu, Constantina, additional, Orsulic, Sandra, additional, Ruebner, Matthias, additional, Schoemaker, Minouk J., additional, Shah, Mitul, additional, Sharma, Raghwa, additional, Sherman, Mark E., additional, Shvetsov, Yurii B., additional, Soong, T. Rinda, additional, Steed, Helen, additional, Sukumvanich, Paniti, additional, Talhouk, Aline, additional, Taylor, Sarah E., additional, Vierkant, Robert A., additional, Wang, Chen, additional, Widschwendter, Martin, additional, Wilkens, Lynne R., additional, Winham, Stacey J., additional, Anglesio, Michael S., additional, Berchuck, Andrew, additional, Brenton, James D., additional, Campbell, Ian, additional, Cook, Linda S., additional, Doherty, Jennifer A., additional, Fasching, Peter A., additional, Fortner, Renée Turzanski., additional, Goodman, Marc T., additional, Gronwald, Jacek, additional, Huntsman, David G., additional, Karlan, Beth Y., additional, Kelemen, Linda E., additional, Menon, Usha, additional, Modugno, Francesmary, additional, Pharoah, Paul D. P., additional, Schildkraut, Joellen M., additional, Sundfeldt, Karin, additional, Swerdlow, Anthony J., additional, Goode, Ellen L., additional, DeFazio, Anna, additional, Köbel, Martin, additional, Ramus, Susan J., additional, Bowtell, David D.L., additional, and Garsed, Dale W., additional

Published
2024
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2. History of infertility and risk of colorectal cancer

Author

Farland, Leslie V., primary, Lind, Kimberly E., additional, Roe, Denise J., additional, Saquib, Nazmus, additional, Strickler, Howard D., additional, Qi, Lihong, additional, Thomson, Cynthia A., additional, and Harris, Holly R., additional

Published
2024
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3. Abstract B037: Physical inactivity is associated with ovarian cancer in women of African ancestry

Author

Minlikeeva, Albina, primary, Lima, Sarah M., additional, Johnson, Courtney, additional, Bandera, Elisa V., additional, Beeghly-Fadiel, Alicia, additional, Bethea, Traci N., additional, Petrick, Jessica, additional, Joslin, Charlotte E., additional, Myers, Evan, additional, Harris, Holly R., additional, Peres, Lauren C., additional, Setiawan, V. Wendy, additional, Wu, Anna H., additional, Rosenberg, Lynn, additional, Schildkraut, Joellen M., additional, and Ochs-Balcom, Heather M., additional

Published
2024
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5. Supplementary Figure 2 from Folate Intake and Ovarian Cancer Risk among Women with Endometriosis: A Case–Control Study from the Ovarian Cancer Association Consortium

Author

Gersekowski, Kate, primary, Ibiebele, Torukiri I, primary, Doherty, Jennifer A., primary, Harris, Holly R., primary, Goodman, Marc T., primary, Terry, Kathryn L., primary, Wu, Anna H., primary, Bandera, Elisa V., primary, Qin, Bo, primary, Ong, Jue-Sheng, primary, Tyrer, Jonathan P., primary, Dixon-Suen, Suzanne C., primary, Modugno, Francesmary, primary, Risch, Harvey A, primary, and Webb, Penelope M., primary

Published
2023
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6. Supplementary Figure 1 from Folate Intake and Ovarian Cancer Risk among Women with Endometriosis: A Case–Control Study from the Ovarian Cancer Association Consortium

Author

Gersekowski, Kate, primary, Ibiebele, Torukiri I, primary, Doherty, Jennifer A., primary, Harris, Holly R., primary, Goodman, Marc T., primary, Terry, Kathryn L., primary, Wu, Anna H., primary, Bandera, Elisa V., primary, Qin, Bo, primary, Ong, Jue-Sheng, primary, Tyrer, Jonathan P., primary, Dixon-Suen, Suzanne C., primary, Modugno, Francesmary, primary, Risch, Harvey A, primary, and Webb, Penelope M., primary

Published
2023
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7. Table 3 from Folate Intake and Ovarian Cancer Risk among Women with Endometriosis: A Case–Control Study from the Ovarian Cancer Association Consortium

Author

Gersekowski, Kate, primary, Ibiebele, Torukiri I, primary, Doherty, Jennifer A., primary, Harris, Holly R., primary, Goodman, Marc T., primary, Terry, Kathryn L., primary, Wu, Anna H., primary, Bandera, Elisa V., primary, Qin, Bo, primary, Ong, Jue-Sheng, primary, Tyrer, Jonathan P., primary, Dixon-Suen, Suzanne C., primary, Modugno, Francesmary, primary, Risch, Harvey A, primary, and Webb, Penelope M., primary

Published
2023
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8. Data from Folate Intake and Ovarian Cancer Risk among Women with Endometriosis: A Case–Control Study from the Ovarian Cancer Association Consortium

Author

Gersekowski, Kate, primary, Ibiebele, Torukiri I, primary, Doherty, Jennifer A., primary, Harris, Holly R., primary, Goodman, Marc T., primary, Terry, Kathryn L., primary, Wu, Anna H., primary, Bandera, Elisa V., primary, Qin, Bo, primary, Ong, Jue-Sheng, primary, Tyrer, Jonathan P., primary, Dixon-Suen, Suzanne C., primary, Modugno, Francesmary, primary, Risch, Harvey A, primary, and Webb, Penelope M., primary

Published
2023
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9. Supplementary Table 2 from Folate Intake and Ovarian Cancer Risk among Women with Endometriosis: A Case–Control Study from the Ovarian Cancer Association Consortium

Author

Gersekowski, Kate, primary, Ibiebele, Torukiri I, primary, Doherty, Jennifer A., primary, Harris, Holly R., primary, Goodman, Marc T., primary, Terry, Kathryn L., primary, Wu, Anna H., primary, Bandera, Elisa V., primary, Qin, Bo, primary, Ong, Jue-Sheng, primary, Tyrer, Jonathan P., primary, Dixon-Suen, Suzanne C., primary, Modugno, Francesmary, primary, Risch, Harvey A, primary, and Webb, Penelope M., primary

Published
2023
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10. Supplementary Table 5 from Folate Intake and Ovarian Cancer Risk among Women with Endometriosis: A Case–Control Study from the Ovarian Cancer Association Consortium

Author

Gersekowski, Kate, primary, Ibiebele, Torukiri I, primary, Doherty, Jennifer A., primary, Harris, Holly R., primary, Goodman, Marc T., primary, Terry, Kathryn L., primary, Wu, Anna H., primary, Bandera, Elisa V., primary, Qin, Bo, primary, Ong, Jue-Sheng, primary, Tyrer, Jonathan P., primary, Dixon-Suen, Suzanne C., primary, Modugno, Francesmary, primary, Risch, Harvey A, primary, and Webb, Penelope M., primary

Published
2023
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11. Supplementary Figure 3 from Folate Intake and Ovarian Cancer Risk among Women with Endometriosis: A Case–Control Study from the Ovarian Cancer Association Consortium

Author

Gersekowski, Kate, primary, Ibiebele, Torukiri I, primary, Doherty, Jennifer A., primary, Harris, Holly R., primary, Goodman, Marc T., primary, Terry, Kathryn L., primary, Wu, Anna H., primary, Bandera, Elisa V., primary, Qin, Bo, primary, Ong, Jue-Sheng, primary, Tyrer, Jonathan P., primary, Dixon-Suen, Suzanne C., primary, Modugno, Francesmary, primary, Risch, Harvey A, primary, and Webb, Penelope M., primary

Published
2023
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12. Supplementary Table 1 from Folate Intake and Ovarian Cancer Risk among Women with Endometriosis: A Case–Control Study from the Ovarian Cancer Association Consortium

Author

Gersekowski, Kate, primary, Ibiebele, Torukiri I, primary, Doherty, Jennifer A., primary, Harris, Holly R., primary, Goodman, Marc T., primary, Terry, Kathryn L., primary, Wu, Anna H., primary, Bandera, Elisa V., primary, Qin, Bo, primary, Ong, Jue-Sheng, primary, Tyrer, Jonathan P., primary, Dixon-Suen, Suzanne C., primary, Modugno, Francesmary, primary, Risch, Harvey A, primary, and Webb, Penelope M., primary

Published
2023
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13. Table 2 from Folate Intake and Ovarian Cancer Risk among Women with Endometriosis: A Case–Control Study from the Ovarian Cancer Association Consortium

Author

Gersekowski, Kate, primary, Ibiebele, Torukiri I, primary, Doherty, Jennifer A., primary, Harris, Holly R., primary, Goodman, Marc T., primary, Terry, Kathryn L., primary, Wu, Anna H., primary, Bandera, Elisa V., primary, Qin, Bo, primary, Ong, Jue-Sheng, primary, Tyrer, Jonathan P., primary, Dixon-Suen, Suzanne C., primary, Modugno, Francesmary, primary, Risch, Harvey A, primary, and Webb, Penelope M., primary

Published
2023
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14. Supplementary Table 3 from Folate Intake and Ovarian Cancer Risk among Women with Endometriosis: A Case–Control Study from the Ovarian Cancer Association Consortium

Author

Gersekowski, Kate, primary, Ibiebele, Torukiri I, primary, Doherty, Jennifer A., primary, Harris, Holly R., primary, Goodman, Marc T., primary, Terry, Kathryn L., primary, Wu, Anna H., primary, Bandera, Elisa V., primary, Qin, Bo, primary, Ong, Jue-Sheng, primary, Tyrer, Jonathan P., primary, Dixon-Suen, Suzanne C., primary, Modugno, Francesmary, primary, Risch, Harvey A, primary, and Webb, Penelope M., primary

Published
2023
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15. Supplementary Table 4 from Folate Intake and Ovarian Cancer Risk among Women with Endometriosis: A Case–Control Study from the Ovarian Cancer Association Consortium

Author

Gersekowski, Kate, primary, Ibiebele, Torukiri I, primary, Doherty, Jennifer A., primary, Harris, Holly R., primary, Goodman, Marc T., primary, Terry, Kathryn L., primary, Wu, Anna H., primary, Bandera, Elisa V., primary, Qin, Bo, primary, Ong, Jue-Sheng, primary, Tyrer, Jonathan P., primary, Dixon-Suen, Suzanne C., primary, Modugno, Francesmary, primary, Risch, Harvey A, primary, and Webb, Penelope M., primary

Published
2023
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16. Table 1 from Folate Intake and Ovarian Cancer Risk among Women with Endometriosis: A Case–Control Study from the Ovarian Cancer Association Consortium

Author

Gersekowski, Kate, primary, Ibiebele, Torukiri I, primary, Doherty, Jennifer A., primary, Harris, Holly R., primary, Goodman, Marc T., primary, Terry, Kathryn L., primary, Wu, Anna H., primary, Bandera, Elisa V., primary, Qin, Bo, primary, Ong, Jue-Sheng, primary, Tyrer, Jonathan P., primary, Dixon-Suen, Suzanne C., primary, Modugno, Francesmary, primary, Risch, Harvey A, primary, and Webb, Penelope M., primary

Published
2023
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17. Folate intake and ovarian cancer risk among women with endometriosis: a case-control study from the Ovarian Cancer Association Consortium

Author

Gersekowski, Kate, primary, Ibiebele, Torukiri I., additional, Doherty, Jennifer A., additional, Harris, Holly R., additional, Goodman, Marc T., additional, Terry, Kathryn L., additional, Wu, Anna H., additional, Bandera, Elisa V., additional, Qin, Bo, additional, Ong, Jue-Sheng, additional, Tyrer, Jonathan P., additional, Dixon-Suen, Suzanne C., additional, Modugno, Francesmary, additional, Risch, Harvey A., additional, and Webb, Penelope M., additional

Published
2023
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22. Supplementary Table 1 from The Risk of Ovarian Cancer Increases with an Increase in the Lifetime Number of Ovulatory Cycles: An Analysis from the Ovarian Cancer Cohort Consortium (OC3)

Author

Trabert, Britton, primary, Tworoger, Shelley S., primary, O'Brien, Katie M., primary, Townsend, Mary K., primary, Fortner, Renée T., primary, Iversen, Edwin S., primary, Hartge, Patricia, primary, White, Emily, primary, Amiano, Pilar, primary, Arslan, Alan A., primary, Bernstein, Leslie, primary, Brinton, Louise A., primary, Buring, Julie E., primary, Dossus, Laure, primary, Fraser, Gary E., primary, Gaudet, Mia M., primary, Giles, Graham G., primary, Gram, Inger T., primary, Harris, Holly R., primary, Bolton, Judith Hoffman, primary, Idahl, Annika, primary, Jones, Michael E., primary, Kaaks, Rudolf, primary, Kirsh, Victoria A., primary, Knutsen, Synnove F., primary, Kvaskoff, Marina, primary, Lacey, James V., primary, Lee, I-Min, primary, Milne, Roger L., primary, Onland-Moret, N. Charlotte, primary, Overvad, Kim, primary, Patel, Alpa V., primary, Peters, Ulrike, primary, Poynter, Jenny N., primary, Riboli, Elio, primary, Robien, Kim, primary, Rohan, Thomas E., primary, Sandler, Dale P., primary, Schairer, Catherine, primary, Schouten, Leo J., primary, Setiawan, Veronica W., primary, Swerdlow, Anthony J., primary, Travis, Ruth C., primary, Trichopoulou, Antonia, primary, van den Brandt, Piet A., primary, Visvanathan, Kala, primary, Wilkens, Lynne R., primary, Wolk, Alicja, primary, Zeleniuch-Jacquotte, Anne, primary, and Wentzensen, Nicolas, primary

Published
2023
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23. Data from The Risk of Ovarian Cancer Increases with an Increase in the Lifetime Number of Ovulatory Cycles: An Analysis from the Ovarian Cancer Cohort Consortium (OC3)

Author

Trabert, Britton, primary, Tworoger, Shelley S., primary, O'Brien, Katie M., primary, Townsend, Mary K., primary, Fortner, Renée T., primary, Iversen, Edwin S., primary, Hartge, Patricia, primary, White, Emily, primary, Amiano, Pilar, primary, Arslan, Alan A., primary, Bernstein, Leslie, primary, Brinton, Louise A., primary, Buring, Julie E., primary, Dossus, Laure, primary, Fraser, Gary E., primary, Gaudet, Mia M., primary, Giles, Graham G., primary, Gram, Inger T., primary, Harris, Holly R., primary, Bolton, Judith Hoffman, primary, Idahl, Annika, primary, Jones, Michael E., primary, Kaaks, Rudolf, primary, Kirsh, Victoria A., primary, Knutsen, Synnove F., primary, Kvaskoff, Marina, primary, Lacey, James V., primary, Lee, I-Min, primary, Milne, Roger L., primary, Onland-Moret, N. Charlotte, primary, Overvad, Kim, primary, Patel, Alpa V., primary, Peters, Ulrike, primary, Poynter, Jenny N., primary, Riboli, Elio, primary, Robien, Kim, primary, Rohan, Thomas E., primary, Sandler, Dale P., primary, Schairer, Catherine, primary, Schouten, Leo J., primary, Setiawan, Veronica W., primary, Swerdlow, Anthony J., primary, Travis, Ruth C., primary, Trichopoulou, Antonia, primary, van den Brandt, Piet A., primary, Visvanathan, Kala, primary, Wilkens, Lynne R., primary, Wolk, Alicja, primary, Zeleniuch-Jacquotte, Anne, primary, and Wentzensen, Nicolas, primary

Published
2023
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24. Supplementary Table 2 from The Risk of Ovarian Cancer Increases with an Increase in the Lifetime Number of Ovulatory Cycles: An Analysis from the Ovarian Cancer Cohort Consortium (OC3)

Author

Trabert, Britton, primary, Tworoger, Shelley S., primary, O'Brien, Katie M., primary, Townsend, Mary K., primary, Fortner, Renée T., primary, Iversen, Edwin S., primary, Hartge, Patricia, primary, White, Emily, primary, Amiano, Pilar, primary, Arslan, Alan A., primary, Bernstein, Leslie, primary, Brinton, Louise A., primary, Buring, Julie E., primary, Dossus, Laure, primary, Fraser, Gary E., primary, Gaudet, Mia M., primary, Giles, Graham G., primary, Gram, Inger T., primary, Harris, Holly R., primary, Bolton, Judith Hoffman, primary, Idahl, Annika, primary, Jones, Michael E., primary, Kaaks, Rudolf, primary, Kirsh, Victoria A., primary, Knutsen, Synnove F., primary, Kvaskoff, Marina, primary, Lacey, James V., primary, Lee, I-Min, primary, Milne, Roger L., primary, Onland-Moret, N. Charlotte, primary, Overvad, Kim, primary, Patel, Alpa V., primary, Peters, Ulrike, primary, Poynter, Jenny N., primary, Riboli, Elio, primary, Robien, Kim, primary, Rohan, Thomas E., primary, Sandler, Dale P., primary, Schairer, Catherine, primary, Schouten, Leo J., primary, Setiawan, Veronica W., primary, Swerdlow, Anthony J., primary, Travis, Ruth C., primary, Trichopoulou, Antonia, primary, van den Brandt, Piet A., primary, Visvanathan, Kala, primary, Wilkens, Lynne R., primary, Wolk, Alicja, primary, Zeleniuch-Jacquotte, Anne, primary, and Wentzensen, Nicolas, primary

Published
2023
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25. Abstract C105: Racial differences in the association of endometriosis and fibroids with risk of ovarian cancer

Author

Harris, Holly, primary, Peres, Lauren, additional, Johnson, Courtney, additional, Guertin, Kristin, additional, Beeghly-Fadiel, Alicia, additional, Bandera, Elisa, additional, Bethea, Traci, additional, Joslin, Charlotte, additional, Wu, Anna, additional, Moorman, Patricia, additional, Ochs-Balcom, Heather, additional, Petrick, Jessica, additional, Setiawan, Veronica, additional, Rosenberg, Lynn, additional, Schildkraut, Joellen, additional, and Myers, Evan, additional

Published
2023
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26. Abstract 736: Exploring the impact of infertility and its treatments on risk of ovarian cancer

Author

Lee, Alice W., primary, Phung, Minh T., additional, Jensen, Allan, additional, Wu, Anna H., additional, Cramer, Daniel W., additional, Modugno, Francesmary, additional, Harris, Holly, additional, Doherty, Jennifer A., additional, Schildkraut, Joellen, additional, Terry, Kathryn L., additional, Moysich, Kirsten B., additional, Pike, Malcolm C., additional, Goodman, Marc T., additional, Webb, Penelope M., additional, Kjaer, Susanne K., additional, and Pearce, Celeste L., additional

Published
2022
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27. Race Differences in the Associations between Menstrual Cycle Characteristics and Epithelial Ovarian Cancer

Author

Nash, Rebecca, primary, Johnson, Courtney E., additional, Harris, Holly R., additional, Peres, Lauren C., additional, Joslin, Charlotte E., additional, Bethea, Traci N., additional, Bandera, Elisa V., additional, Ochs-Balcom, Heather M., additional, Myers, Evan R., additional, Guertin, Kristin A., additional, Camacho, Fabian, additional, Beeghly-Fadiel, Alicia, additional, Moorman, Patricia G., additional, Setiawan, V. Wendy, additional, Rosenberg, Lynn, additional, Schildkraut, Joellen M., additional, and Wu, Anna H., additional

Published
2022
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28. High Prediagnosis Inflammation-Related Risk Score Associated with Decreased Ovarian Cancer Survival

Author

Brieger, Katharine K., primary, Phung, Minh Tung, additional, Mukherjee, Bhramar, additional, Bakulski, Kelly M., additional, Anton-Culver, Hoda, additional, Bandera, Elisa V., additional, Bowtell, David D.L., additional, Cramer, Daniel W., additional, DeFazio, Anna, additional, Doherty, Jennifer A., additional, Fereday, Sian, additional, Fortner, Renée Turzanski, additional, Gentry-Maharaj, Aleksandra, additional, Goode, Ellen L., additional, Goodman, Marc T., additional, Harris, Holly R., additional, Matsuo, Keitaro, additional, Menon, Usha, additional, Modugno, Francesmary, additional, Moysich, Kirsten B., additional, Qin, Bo, additional, Ramus, Susan J., additional, Risch, Harvey A., additional, Rossing, Mary Anne, additional, Schildkraut, Joellen M., additional, Trabert, Britton, additional, Vierkant, Robert A., additional, Winham, Stacey J., additional, Wentzensen, Nicolas, additional, Wu, Anna H., additional, Ziogas, Argyrios, additional, Khoja, Lilah, additional, Cho, Kathleen R., additional, McLean, Karen, additional, Richardson, Jean, additional, Grout, Bronwyn, additional, Chase, Anne, additional, Deurloo, Cindy McKinnon, additional, Odunsi, Kunle, additional, Nelson, Brad H., additional, Brenton, James D., additional, Terry, Kathryn L., additional, Pharoah, Paul D.P., additional, Berchuck, Andrew, additional, Hanley, Gillian E., additional, Webb, Penelope M., additional, Pike, Malcolm C., additional, and Pearce, Celeste Leigh, additional

Published
2022
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29. Genital Powder Use and Risk of Epithelial Ovarian Cancer in the Ovarian Cancer in Women of African Ancestry Consortium

Author

Davis, Colette P., primary, Bandera, Elisa V., additional, Bethea, Traci N., additional, Camacho, Fabian, additional, Joslin, Charlotte E., additional, Wu, Anna H., additional, Beeghly-Fadiel, Alicia, additional, Moorman, Patricia G., additional, Myers, Evan R., additional, Ochs-Balcom, Heather M., additional, Peres, Lauren C., additional, Rosenow, Will T., additional, Setiawan, Veronica W., additional, Rosenberg, Lynn, additional, Schildkraut, Joellen M., additional, and Harris, Holly R., additional

Published
2021
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31. Depot-Medroxyprogesterone Acetate Use Is Associated with Decreased Risk of Ovarian Cancer: The Mounting Evidence of a Protective Role of Progestins

Author

Phung, Minh Tung, primary, Lee, Alice W., additional, Wu, Anna H., additional, Berchuck, Andrew, additional, Cho, Kathleen R., additional, Cramer, Daniel W., additional, Doherty, Jennifer Anne, additional, Goodman, Marc T., additional, Hanley, Gillian E., additional, Harris, Holly R., additional, McLean, Karen, additional, Modugno, Francesmary, additional, Moysich, Kirsten B., additional, Mukherjee, Bhramar, additional, Schildkraut, Joellen M., additional, Terry, Kathryn L., additional, Titus, Linda J., additional, Jordan, Susan J., additional, Webb, Penelope M., additional, Pike, Malcolm C., additional, and Pearce, Celeste Leigh, additional

Published
2021
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34. Development and Validation of the Gene Expression Predictor of High-grade Serous Ovarian Carcinoma Molecular SubTYPE (PrOTYPE)

Author

Talhouk, Aline, primary, George, Joshy, additional, Wang, Chen, additional, Budden, Timothy, additional, Tan, Tuan Zea, additional, Chiu, Derek S., additional, Kommoss, Stefan, additional, Leong, Huei San, additional, Chen, Stephanie, additional, Intermaggio, Maria P., additional, Gilks, Blake, additional, Nazeran, Tayyebeh M., additional, Volchek, Mila, additional, Elatre, Wafaa, additional, Bentley, Rex C., additional, Senz, Janine, additional, Lum, Amy, additional, Chow, Veronica, additional, Sudderuddin, Hanwei, additional, Mackenzie, Robertson, additional, Leong, Samuel C.Y., additional, Liu, Geyi, additional, Johnson, Dustin, additional, Chen, Billy, additional, Group, AOCS, additional, Alsop, Jennifer, additional, Banerjee, Susana N., additional, Behrens, Sabine, additional, Bodelon, Clara, additional, Brand, Alison H., additional, Brinton, Louise, additional, Carney, Michael E., additional, Chiew, Yoke-Eng, additional, Cushing-Haugen, Kara L., additional, Cybulski, Cezary, additional, Ennis, Darren, additional, Fereday, Sian, additional, Fortner, Renée T., additional, García-Donas, Jesús, additional, Gentry-Maharaj, Aleksandra, additional, Glasspool, Rosalind, additional, Goranova, Teodora, additional, Greene, Casey S., additional, Haluska, Paul, additional, Harris, Holly R., additional, Hendley, Joy, additional, Hernandez, Brenda Y., additional, Herpel, Esther, additional, Jimenez-Linan, Mercedes, additional, Karpinskyj, Chloe, additional, Kaufmann, Scott H., additional, Keeney, Gary L., additional, Kennedy, Catherine J., additional, Köbel, Martin, additional, Koziak, Jennifer M., additional, Larson, Melissa C., additional, Lester, Jenny, additional, Lewsley, Liz-Anne, additional, Lissowska, Jolanta, additional, Lubiński, Jan, additional, Luk, Hugh, additional, Macintyre, Geoff, additional, Mahner, Sven, additional, McNeish, Iain A., additional, Menkiszak, Janusz, additional, Nevins, Nikilyn, additional, Osorio, Ana, additional, Oszurek, Oleg, additional, Palacios, José, additional, Hinsley, Samantha, additional, Pearce, Celeste L., additional, Pike, Malcolm C., additional, Piskorz, Anna M., additional, Ray-Coquard, Isabelle, additional, Rhenius, Valerie, additional, Rodriguez-Antona, Cristina, additional, Sharma, Raghwa, additional, Sherman, Mark E., additional, De Silva, Dilrini, additional, Singh, Naveena, additional, Sinn, Peter, additional, Slamon, Dennis, additional, Song, Honglin, additional, Steed, Helen, additional, Stronach, Euan A., additional, Thompson, Pamela J., additional, Tołoczko, Aleksandra, additional, Trabert, Britton, additional, Traficante, Nadia, additional, Tseng, Chiu-Chen, additional, Widschwendter, Martin, additional, Wilkens, Lynne R., additional, Winham, Stacey J., additional, Winterhoff, Boris, additional, Beeghly-Fadiel, Alicia, additional, Benitez, Javier, additional, Berchuck, Andrew, additional, Brenton, James D., additional, Brown, Robert, additional, Chang-Claude, Jenny, additional, Chenevix-Trench, Georgia, additional, deFazio, Anna, additional, Fasching, Peter A., additional, García, María J., additional, Gayther, Simon A., additional, Goodman, Marc T., additional, Gronwald, Jacek, additional, Henderson, Michelle J., additional, Karlan, Beth Y., additional, Kelemen, Linda E., additional, Menon, Usha, additional, Orsulic, Sandra, additional, Pharoah, Paul D.P., additional, Wentzensen, Nicolas, additional, Wu, Anna H., additional, Schildkraut, Joellen M., additional, Rossing, Mary Anne, additional, Konecny, Gottfried E., additional, Huntsman, David G., additional, Huang, Ruby Yun-Ju, additional, Goode, Ellen L., additional, Ramus, Susan J., additional, Doherty, Jennifer A., additional, Bowtell, David D., additional, and Anglesio, Michael S., additional

Published
2020
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35. Ovarian Cancer Risk Factor Associations by Primary Anatomic Site: The Ovarian Cancer Cohort Consortium

Author

Fortner, Renée T., primary, Rice, Megan S., additional, Knutsen, Synnove F., additional, Orlich, Michael J., additional, Visvanathan, Kala, additional, Patel, Alpa V., additional, Gaudet, Mia M., additional, Tjønneland, Anne, additional, Kvaskoff, Marina, additional, Kaaks, Rudolf, additional, Trichopolou, Antonia, additional, Pala, Valeria, additional, Onland-Moret, N. Charlotte, additional, Gram, Inger T., additional, Amiano, Pilar, additional, Idahl, Annika, additional, Allen, Naomi E., additional, Weiderpass, Elisabete, additional, Poynter, Jenny N., additional, Robien, Kim, additional, Giles, Graham G., additional, Milne, Roger L., additional, Setiawan, Veronica W., additional, Merritt, Melissa A., additional, van den Brandt, Piet A., additional, Zeleniuch-Jacquotte, Anne, additional, Arslan, Alan A., additional, O'Brien, Katie M., additional, Sandler, Dale P., additional, Wolk, Alicja, additional, Håkansson, Niclas, additional, Harris, Holly R., additional, Trabert, Britton, additional, Wentzensen, Nicolas, additional, Tworoger, Shelley S., additional, and Schouten, Leo J., additional

Published
2020
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36. Abstract 1180: Estimating the contribution of epidemiologic risk factors to racial differences in epithelial ovarian cancer incidence

Author

Peres, Lauren C., primary, Camacho, Tareq F., additional, Bandera, Elisa V., additional, Bethea, Traci N., additional, Joslin, Charlotte E., additional, Wu, Anna H., additional, Beeghly-Fadiel, Alicia, additional, Cloyd, Emily K., additional, Harris, Holly R., additional, Moorman, Patricia G., additional, Myers, Evan, additional, Ochs-Balcom, Heather M., additional, Rosenow, Will L., additional, Setiawan, Veronica W., additional, Rosenberg, Lynn, additional, and Schildkraut, Joellen M., additional

Published
2020
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37. Abstract 3498: Ovarian cancer risk factors multiply to create high risk in pre-menopausal women

Author

Phung, Minh Tung, primary, Mukherjee, Bhramar, additional, Lee, Alice W., additional, Webb, Penelope M., additional, Risch, Harvey A., additional, Doherty, Jennifer Anne, additional, Harris, Holly R., additional, Goodman, Marc T., additional, Ness, Roberta B., additional, Modugno, Francesmary, additional, Jensen, Allan, additional, Kjaer, Susanne K., additional, Terry, Kathryn L., additional, Cramer, Daniel W., additional, Ziogas, Argyrios, additional, Anton-Culver, Hoda, additional, Pike, Malcolm C., additional, Wu, Anna H., additional, and Pearce, Celeste Leigh, additional

Published
2020
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38. Abstract C070: Racial disparities in body mass index and ovarian cancer risk in the OCWAA Consortium

Author

Bandera, Elisa V, primary, Camacho, Fabian, additional, Chyn, Deanna, additional, Cloyd, Emily K, additional, Bethea, Traci N, additional, Beeghly-Fadiel, Alicia, additional, Joslin, Charlotte E, additional, Myers, Evan, additional, Moorman, Patricia G, additional, Ochs-Balcom, Heather M, additional, Harris, Holly R, additional, Peres, Lauren C, additional, Setiawan, Veronica Wendy, additional, Wu, Anna H, additional, Rosenberg, Lynn, additional, and Schildkraut, Joellen M, additional

Published
2020
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39. Abstract C038: First- and second-degree family history of ovarian and breast cancers in relation to risk of invasive ovarian cancer in African American and White women

Author

Bethea, Traci N., primary, Ochs-Balcom, Heather M., additional, Bandera, Elisa V., additional, Beeghly-Fadiel, Alicia, additional, Camancho, Fabian, additional, Cloyd, Emily K., additional, Harris, Holly R., additional, Joslin, Charlotte E., additional, Myers, Evan, additional, Moorman, Patricia G., additional, Peres, Lauren C., additional, Setiawan, Veronica W., additional, Wu, Anna H., additional, Rosenberg, Lynn, additional, and Schildkraut, Joellen M., additional

Published
2020
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40. The Risk of Ovarian Cancer Increases with an Increase in the Lifetime Number of Ovulatory Cycles: An Analysis from the Ovarian Cancer Cohort Consortium (OC3)

Author

Trabert, Britton, primary, Tworoger, Shelley S., additional, O'Brien, Katie M., additional, Townsend, Mary K., additional, Fortner, Renée T., additional, Iversen, Edwin S., additional, Hartge, Patricia, additional, White, Emily, additional, Amiano, Pilar, additional, Arslan, Alan A., additional, Bernstein, Leslie, additional, Brinton, Louise A., additional, Buring, Julie E., additional, Dossus, Laure, additional, Fraser, Gary E., additional, Gaudet, Mia M., additional, Giles, Graham G., additional, Gram, Inger T., additional, Harris, Holly R., additional, Bolton, Judith Hoffman, additional, Idahl, Annika, additional, Jones, Michael E., additional, Kaaks, Rudolf, additional, Kirsh, Victoria A., additional, Knutsen, Synnove F., additional, Kvaskoff, Marina, additional, Lacey, James V., additional, Lee, I-Min, additional, Milne, Roger L., additional, Onland-Moret, N. Charlotte, additional, Overvad, Kim, additional, Patel, Alpa V., additional, Peters, Ulrike, additional, Poynter, Jenny N., additional, Riboli, Elio, additional, Robien, Kim, additional, Rohan, Thomas E., additional, Sandler, Dale P., additional, Schairer, Catherine, additional, Schouten, Leo J., additional, Setiawan, Veronica W., additional, Swerdlow, Anthony J., additional, Travis, Ruth C., additional, Trichopoulou, Antonia, additional, van den Brandt, Piet A., additional, Visvanathan, Kala, additional, Wilkens, Lynne R., additional, Wolk, Alicja, additional, Zeleniuch-Jacquotte, Anne, additional, and Wentzensen, Nicolas, additional

Published
2020
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42. Genetic Data from Nearly 63,000 Women of European Descent Predicts DNA Methylation Biomarkers and Epithelial Ovarian Cancer Risk

Author

Yang, Yaohua, primary, Wu, Lang, additional, Shu, Xiang, additional, Lu, Yingchang, additional, Shu, Xiao-Ou, additional, Cai, Qiuyin, additional, Beeghly-Fadiel, Alicia, additional, Li, Bingshan, additional, Ye, Fei, additional, Berchuck, Andrew, additional, Anton-Culver, Hoda, additional, Banerjee, Susana, additional, Benitez, Javier, additional, Bjørge, Line, additional, Brenton, James D., additional, Butzow, Ralf, additional, Campbell, Ian G., additional, Chang-Claude, Jenny, additional, Chen, Kexin, additional, Cook, Linda S., additional, Cramer, Daniel W., additional, deFazio, Anna, additional, Dennis, Joe, additional, Doherty, Jennifer A., additional, Dörk, Thilo, additional, Eccles, Diana M., additional, Edwards, Digna Velez, additional, Fasching, Peter A., additional, Fortner, Renée T., additional, Gayther, Simon A., additional, Giles, Graham G., additional, Glasspool, Rosalind M., additional, Goode, Ellen L., additional, Goodman, Marc T., additional, Gronwald, Jacek, additional, Harris, Holly R., additional, Heitz, Florian, additional, Hildebrandt, Michelle A., additional, Høgdall, Estrid, additional, Høgdall, Claus K., additional, Huntsman, David G., additional, Kar, Siddhartha P., additional, Karlan, Beth Y., additional, Kelemen, Linda E., additional, Kiemeney, Lambertus A., additional, Kjaer, Susanne K., additional, Koushik, Anita, additional, Lambrechts, Diether, additional, Le, Nhu D., additional, Levine, Douglas A., additional, Massuger, Leon F., additional, Matsuo, Keitaro, additional, May, Taymaa, additional, McNeish, Iain A., additional, Menon, Usha, additional, Modugno, Francesmary, additional, Monteiro, Alvaro N., additional, Moorman, Patricia G., additional, Moysich, Kirsten B., additional, Ness, Roberta B., additional, Nevanlinna, Heli, additional, Olsson, Håkan, additional, Onland-Moret, N. Charlotte, additional, Park, Sue K., additional, Paul, James, additional, Pearce, Celeste L., additional, Pejovic, Tanja, additional, Phelan, Catherine M., additional, Pike, Malcolm C., additional, Ramus, Susan J., additional, Riboli, Elio, additional, Rodriguez-Antona, Cristina, additional, Romieu, Isabelle, additional, Sandler, Dale P., additional, Schildkraut, Joellen M., additional, Setiawan, Veronica W., additional, Shan, Kang, additional, Siddiqui, Nadeem, additional, Sieh, Weiva, additional, Stampfer, Meir J., additional, Sutphen, Rebecca, additional, Swerdlow, Anthony J., additional, Szafron, Lukasz M., additional, Teo, Soo Hwang, additional, Tworoger, Shelley S., additional, Tyrer, Jonathan P., additional, Webb, Penelope M., additional, Wentzensen, Nicolas, additional, White, Emily, additional, Willett, Walter C., additional, Wolk, Alicja, additional, Woo, Yin Ling, additional, Wu, Anna H., additional, Yan, Li, additional, Yannoukakos, Drakoulis, additional, Chenevix-Trench, Georgia, additional, Sellers, Thomas A., additional, Pharoah, Paul D.P., additional, Zheng, Wei, additional, and Long, Jirong, additional

Published
2019
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44. Polycystic Ovary Syndrome, Oligomenorrhea, and Risk of Ovarian Cancer Histotypes: Evidence from the Ovarian Cancer Association Consortium

Author

Harris, Holly R., primary, Babic, Ana, additional, Webb, Penelope M., additional, Nagle, Christina M., additional, Jordan, Susan J., additional, Risch, Harvey A., additional, Rossing, Mary Anne, additional, Doherty, Jennifer A., additional, Goodman, Marc T., additional, Modugno, Francesmary, additional, Ness, Roberta B., additional, Moysich, Kirsten B., additional, Kjær, Susanne K., additional, Høgdall, Estrid, additional, Jensen, Allan, additional, Schildkraut, Joellen M., additional, Berchuck, Andrew, additional, Cramer, Daniel W., additional, Bandera, Elisa V., additional, Wentzensen, Nicolas, additional, Kotsopoulos, Joanne, additional, Narod, Steven A., additional, Phelan, Catherine M., additional, McLaughlin, John R., additional, Anton-Culver, Hoda, additional, Ziogas, Argyrios, additional, Pearce, Celeste L., additional, Wu, Anna H., additional, and Terry, Kathryn L., additional

Published
2018
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50. Development and Validation of the Gene Expression Predictor of High-grade Serous Ovarian Carcinoma Molecular SubTYPE (PrOTYPE)

Author

Sven Mahner, Robertson Mackenzie, Aline Talhouk, Linda E. Kelemen, Gottfried E. Konecny, Jennifer Alsop, Rosalind Glasspool, Chiu-Chen Tseng, Joy Hendley, Dennis J. Slamon, Jennifer A. Doherty, Andrew Berchuck, Anna H. Wu, Anna M. Piskorz, Chen Wang, Cristina Rodríguez-Antona, D.G.H. de Silva, Valerie Rhenius, Peter A. Fasching, Stacey J. Winham, Gary L. Keeney, Teodora Goranova, Joshy George, Jan Lubinski, Michelle J. Henderson, Rex C. Bentley, Jenny Lester, Sabine Behrens, Joellen M. Schildkraut, Michael E. Carney, Timothy Budden, David G. Huntsman, Oleg Oszurek, Michael S. Anglesio, Jacek Gronwald, Ruby Yun-Ju Huang, Martin Köbel, Javier Benitez, Martin Widschwendter, Melissa C. Larson, Raghwa Sharma, Clara Bodelon, Usha Menon, Janusz Menkiszak, Blake Gilks, María Josefa Mosteiro García, Jesús García-Donas, Wafaa Elatre, Scott H. Kaufmann, Paul Haluska, Pamela J. Thompson, Boris Winterhoff, Susan J. Ramus, Louise A. Brinton, Simon A. Gayther, Mary Anne Rossing, Georgia Chenevix-Trench, Hugh Luk, Jolanta Lissowska, Marc T. Goodman, Billy Chen, Beth Y. Karlan, Naveena Singh, Sian Fereday, Mark E. Sherman, Ana Osorio, Lynne R. Wilkens, Maria P. Intermaggio, Brenda Y. Hernandez, Britton Trabert, Esther Herpel, Mercedes Jimenez-Linan, Janine Senz, Geyi Liu, Celeste Leigh Pearce, Samuel C Y Leong, Iain A. McNeish, Isabelle Ray-Coquard, Susana Banerjee, Malcolm C. Pike, Liz-Anne Lewsley, Helen Steed, Honglin Song, Samantha Hinsley, David D.L. Bowtell, James D. Brenton, Holly R. Harris, Tuan Zea Tan, Cezary Cybulski, Alicia Beeghly-Fadiel, A. Toloczko, Nikilyn Nevins, Robert S. Brown, Darren Ennis, Stephanie Chen, Euan A. Stronach, José Palacios, Sandra Orsulic, Anna deFazio, Geoff Macintyre, Kara L. Cushing-Haugen, Mila Volchek, Aleksandra Gentry-Maharaj, Jenny Chang-Claude, Ellen L. Goode, Paul D.P. Pharoah, Hanwei Sudderuddin, Stefan Kommoss, Derek S. Chiu, Huei San Leong, Peter Sinn, Catherine J. Kennedy, Chloe Karpinskyj, Alison Brand, Amy Lum, Veronica Chow, Nicolas Wentzensen, Tayyebeh M. Nazeran, Nadia Traficante, Dustin Johnson, Yoke-Eng Chiew, Casey S. Greene, Jennifer M Koziak, Renée T. Fortner, Imperial College Healthcare NHS Trust- BRC Funding, Cancer Research UK, Ovarian Cancer Action, Talhouk, Aline [0000-0001-7760-410X], George, Joshy [0000-0001-8510-8229], Wang, Chen [0000-0003-2638-3081], Tan, Tuan Zea [0000-0001-6624-1593], Behrens, Sabine [0000-0002-9714-104X], Bodelon, Clara [0000-0002-6578-2678], Brinton, Louise [0000-0003-3853-8562], Fortner, Renée T [0000-0002-1426-8505], García-Donas, Jesús [0000-0001-7731-3601], Gentry-Maharaj, Aleksandra [0000-0001-7270-9762], Glasspool, Rosalind [0000-0002-5000-1680], Greene, Casey S [0000-0001-8713-9213], Harris, Holly R [0000-0002-2572-6727], Kaufmann, Scott H [0000-0002-4900-7145], Kennedy, Catherine J [0000-0002-4465-5784], Köbel, Martin [0000-0002-6615-2037], Koziak, Jennifer M [0000-0001-5830-0397], Lissowska, Jolanta [0000-0003-2695-5799], McNeish, Iain A [0000-0002-9387-7586], Menkiszak, Janusz [0000-0001-8279-7196], Hinsley, Samantha [0000-0001-6903-4688], Pike, Malcolm C [0000-0003-4891-1199], Rodriguez-Antona, Cristina [0000-0001-8750-7338], Sinn, Peter [0000-0003-2836-6699], Trabert, Britton [0000-0002-1539-6090], Widschwendter, Martin [0000-0002-7778-8380], Winham, Stacey J [0000-0002-8492-9102], Brenton, James D [0000-0002-5738-6683], Brown, Robert [0000-0001-7960-5755], Chang-Claude, Jenny [0000-0001-8919-1971], deFazio, Anna [0000-0003-0057-4744], Fasching, Peter A [0000-0003-4885-8471], Kelemen, Linda E [0000-0003-4362-9784], Menon, Usha [0000-0003-3708-1732], Pharoah, Paul DP [0000-0001-8494-732X], Ramus, Susan J [0000-0003-0005-7798], Doherty, Jennifer A [0000-0002-1454-8187], Anglesio, Michael S [0000-0003-1639-5003], and Apollo - University of Cambridge Repository

Subjects
0301 basic medicine, Oncology, Cancer Research, medicine.medical_specialty, Neoplasm, Residual, Bevacizumab, 03 medical and health sciences, Ovarian tumor, Lymphocytes, Tumor-Infiltrating, 0302 clinical medicine, Ovarian carcinoma, Internal medicine, medicine, Humans, 1112 Oncology and Carcinogenesis, Oncology & Carcinogenesis, Stage (cooking), Aged, Ovarian Neoplasms, business.industry, Cystadenoma, Serous, Cancer, Middle Aged, Precision medicine, Omics, medicine.disease, Neoplasm Proteins, Gene Expression Regulation, Neoplastic, Serous fluid, 030104 developmental biology, 030220 oncology & carcinogenesis, Female, Neoplasm Grading, Transcriptome, business, Algorithms, medicine.drug
Abstract

Purpose: Gene expression–based molecular subtypes of high-grade serous tubo-ovarian cancer (HGSOC), demonstrated across multiple studies, may provide improved stratification for molecularly targeted trials. However, evaluation of clinical utility has been hindered by nonstandardized methods, which are not applicable in a clinical setting. We sought to generate a clinical grade minimal gene set assay for classification of individual tumor specimens into HGSOC subtypes and confirm previously reported subtype-associated features. Experimental Design: Adopting two independent approaches, we derived and internally validated algorithms for subtype prediction using published gene expression data from 1,650 tumors. We applied resulting models to NanoString data on 3,829 HGSOCs from the Ovarian Tumor Tissue Analysis consortium. We further developed, confirmed, and validated a reduced, minimal gene set predictor, with methods suitable for a single-patient setting. Results: Gene expression data were used to derive the predictor of high-grade serous ovarian carcinoma molecular subtype (PrOTYPE) assay. We established a de facto standard as a consensus of two parallel approaches. PrOTYPE subtypes are significantly associated with age, stage, residual disease, tumor-infiltrating lymphocytes, and outcome. The locked-down clinical grade PrOTYPE test includes a model with 55 genes that predicted gene expression subtype with >95% accuracy that was maintained in all analytic and biological validations. Conclusions: We validated the PrOTYPE assay following the Institute of Medicine guidelines for the development of omics-based tests. This fully defined and locked-down clinical grade assay will enable trial design with molecular subtype stratification and allow for objective assessment of the predictive value of HGSOC molecular subtypes in precision medicine applications. See related commentary by McMullen et al., p. 5271

Published
2020

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