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45 results on '"Chin, Y"'

13. Supplementary Tables from Acetylation within the N- and C-Terminal Domains of Src Regulates Distinct Roles of STAT3-Mediated Tumorigenesis

Author

Huang, Chao, primary, Zhang, Zhe, primary, Chen, Lihan, primary, Lee, Hank W., primary, Ayrapetov, Marina K., primary, Zhao, Ting C., primary, Hao, Yimei, primary, Gao, Jinsong, primary, Yang, Chunzhang, primary, Mehta, Gautam U., primary, Zhuang, Zhengping, primary, Zhang, Xiaoren, primary, Hu, Guohong, primary, and Chin, Y. Eugene, primary

Published
2023
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14. Figure S1 from Acetylation within the N- and C-Terminal Domains of Src Regulates Distinct Roles of STAT3-Mediated Tumorigenesis

Author

Huang, Chao, primary, Zhang, Zhe, primary, Chen, Lihan, primary, Lee, Hank W., primary, Ayrapetov, Marina K., primary, Zhao, Ting C., primary, Hao, Yimei, primary, Gao, Jinsong, primary, Yang, Chunzhang, primary, Mehta, Gautam U., primary, Zhuang, Zhengping, primary, Zhang, Xiaoren, primary, Hu, Guohong, primary, and Chin, Y. Eugene, primary

Published
2023
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15. Supplementary Data from Senescent Stromal Cells Promote Cancer Resistance through SIRT1 Loss-Potentiated Overproduction of Small Extracellular Vesicles

Author

Han, Liu, primary, Long, Qilai, primary, Li, Shenjun, primary, Xu, Qixia, primary, Zhang, Boyi, primary, Dou, Xuefeng, primary, Qian, Min, primary, Jiramongkol, Yannasittha, primary, Guo, Jianming, primary, Cao, Liu, primary, Chin, Y. Eugene, primary, Lam, Eric W.-F., primary, Jiang, Jing, primary, and Sun, Yu, primary

Published
2023
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16. Data from Senescent Stromal Cells Promote Cancer Resistance through SIRT1 Loss-Potentiated Overproduction of Small Extracellular Vesicles

Author

Han, Liu, primary, Long, Qilai, primary, Li, Shenjun, primary, Xu, Qixia, primary, Zhang, Boyi, primary, Dou, Xuefeng, primary, Qian, Min, primary, Jiramongkol, Yannasittha, primary, Guo, Jianming, primary, Cao, Liu, primary, Chin, Y. Eugene, primary, Lam, Eric W.-F., primary, Jiang, Jing, primary, and Sun, Yu, primary

Published
2023
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17. Data from Acetylation within the N- and C-Terminal Domains of Src Regulates Distinct Roles of STAT3-Mediated Tumorigenesis

Author

Huang, Chao, primary, Zhang, Zhe, primary, Chen, Lihan, primary, Lee, Hank W., primary, Ayrapetov, Marina K., primary, Zhao, Ting C., primary, Hao, Yimei, primary, Gao, Jinsong, primary, Yang, Chunzhang, primary, Mehta, Gautam U., primary, Zhuang, Zhengping, primary, Zhang, Xiaoren, primary, Hu, Guohong, primary, and Chin, Y. Eugene, primary

Published
2023
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18. Data from RhoB Differentially Controls Akt Function in Tumor Cells and Stromal Endothelial Cells during Breast Tumorigenesis

Author

Kazerounian, Shiva, primary, Gerald, Damien, primary, Huang, Minzhou, primary, Chin, Y. Rebecca, primary, Udayakumar, Durga, primary, Zheng, Ningning, primary, O'Donnell, Rebekah K., primary, Perruzzi, Carole, primary, Mangiante, Lee, primary, Pourat, Jacob, primary, Phung, Thuy L., primary, Bravo-Nuevo, Arturo, primary, Shechter, Sharon, primary, McNamara, Stephanie, primary, DuHadaway, James B., primary, Kocher, Olivier N., primary, Brown, Lawrence F., primary, Toker, Alex, primary, Prendergast, George C., primary, and Benjamin, Laura E., primary

Published
2023
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19. Data from 3-Phosphoinositide–Dependent Kinase 1 Potentiates Upstream Lesions on the Phosphatidylinositol 3-Kinase Pathway in Breast Carcinoma

Author

Maurer, Matthew, primary, Su, Tao, primary, Saal, Lao H., primary, Koujak, Susan, primary, Hopkins, Benjamin D., primary, Barkley, Christina R., primary, Wu, Jiaping, primary, Nandula, Subhadra, primary, Dutta, Bhaskar, primary, Xie, Yuli, primary, Chin, Y. Rebecca, primary, Kim, Da-In, primary, Ferris, Jennifer S., primary, Gruvberger-Saal, Sofia K., primary, Laakso, Mervi, primary, Wang, Xiaomei, primary, Memeo, Lorenzo, primary, Rojtman, Albert, primary, Matos, Tulio, primary, Yu, Jennifer S., primary, Cordon-Cardo, Carlos, primary, Isola, Jorma, primary, Terry, Mary Beth, primary, Toker, Alex, primary, Mills, Gordon B., primary, Zhao, Jean J., primary, Murty, Vundavalli V.V.S., primary, Hibshoosh, Hanina, primary, and Parsons, Ramon, primary

Published
2023
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22. Supplementary Figure 6 from RhoB Differentially Controls Akt Function in Tumor Cells and Stromal Endothelial Cells during Breast Tumorigenesis

Author

Kazerounian, Shiva, primary, Gerald, Damien, primary, Huang, Minzhou, primary, Chin, Y. Rebecca, primary, Udayakumar, Durga, primary, Zheng, Ningning, primary, O'Donnell, Rebekah K., primary, Perruzzi, Carole, primary, Mangiante, Lee, primary, Pourat, Jacob, primary, Phung, Thuy L., primary, Bravo-Nuevo, Arturo, primary, Shechter, Sharon, primary, McNamara, Stephanie, primary, DuHadaway, James B., primary, Kocher, Olivier N., primary, Brown, Lawrence F., primary, Toker, Alex, primary, Prendergast, George C., primary, and Benjamin, Laura E., primary

Published
2023
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23. Supplementary Information, Methods, Table 1, Figures 1-7 from 3-Phosphoinositide–Dependent Kinase 1 Potentiates Upstream Lesions on the Phosphatidylinositol 3-Kinase Pathway in Breast Carcinoma

Author

Maurer, Matthew, primary, Su, Tao, primary, Saal, Lao H., primary, Koujak, Susan, primary, Hopkins, Benjamin D., primary, Barkley, Christina R., primary, Wu, Jiaping, primary, Nandula, Subhadra, primary, Dutta, Bhaskar, primary, Xie, Yuli, primary, Chin, Y. Rebecca, primary, Kim, Da-In, primary, Ferris, Jennifer S., primary, Gruvberger-Saal, Sofia K., primary, Laakso, Mervi, primary, Wang, Xiaomei, primary, Memeo, Lorenzo, primary, Rojtman, Albert, primary, Matos, Tulio, primary, Yu, Jennifer S., primary, Cordon-Cardo, Carlos, primary, Isola, Jorma, primary, Terry, Mary Beth, primary, Toker, Alex, primary, Mills, Gordon B., primary, Zhao, Jean J., primary, Murty, Vundavalli V.V.S., primary, Hibshoosh, Hanina, primary, and Parsons, Ramon, primary

Published
2023
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24. Data from Lung Tumor Suppressor GPRC5A Binds EGFR and Restrains Its Effector Signaling

Author

Zhong, Shuangshuang, primary, Yin, Huijing, primary, Liao, Yueling, primary, Yao, Feng, primary, Li, Qi, primary, Zhang, Jie, primary, Jiao, Huike, primary, Zhao, Yongxu, primary, Xu, Dongliang, primary, Liu, Shuli, primary, Song, Hongyong, primary, Gao, Yong, primary, Liu, Jingyi, primary, Ma, Lina, primary, Pang, Zhi, primary, Yang, Ruixu, primary, Ding, Chengyi, primary, Sun, Beibei, primary, Lin, Xiaofeng, primary, Ye, Xiaofeng, primary, Guo, Wenzheng, primary, Han, Baohui, primary, Zhou, Binhua P., primary, Chin, Y. Eugene, primary, and Deng, Jiong, primary

Published
2023
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26. Supplementary Figure 5 from RhoB Differentially Controls Akt Function in Tumor Cells and Stromal Endothelial Cells during Breast Tumorigenesis

Author

Kazerounian, Shiva, primary, Gerald, Damien, primary, Huang, Minzhou, primary, Chin, Y. Rebecca, primary, Udayakumar, Durga, primary, Zheng, Ningning, primary, O'Donnell, Rebekah K., primary, Perruzzi, Carole, primary, Mangiante, Lee, primary, Pourat, Jacob, primary, Phung, Thuy L., primary, Bravo-Nuevo, Arturo, primary, Shechter, Sharon, primary, McNamara, Stephanie, primary, DuHadaway, James B., primary, Kocher, Olivier N., primary, Brown, Lawrence F., primary, Toker, Alex, primary, Prendergast, George C., primary, and Benjamin, Laura E., primary

Published
2023
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27. Supplementary Figure 4 from RhoB Differentially Controls Akt Function in Tumor Cells and Stromal Endothelial Cells during Breast Tumorigenesis

Author

Kazerounian, Shiva, primary, Gerald, Damien, primary, Huang, Minzhou, primary, Chin, Y. Rebecca, primary, Udayakumar, Durga, primary, Zheng, Ningning, primary, O'Donnell, Rebekah K., primary, Perruzzi, Carole, primary, Mangiante, Lee, primary, Pourat, Jacob, primary, Phung, Thuy L., primary, Bravo-Nuevo, Arturo, primary, Shechter, Sharon, primary, McNamara, Stephanie, primary, DuHadaway, James B., primary, Kocher, Olivier N., primary, Brown, Lawrence F., primary, Toker, Alex, primary, Prendergast, George C., primary, and Benjamin, Laura E., primary

Published
2023
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28. Supplementary Figures S1-S8 from Lung Tumor Suppressor GPRC5A Binds EGFR and Restrains Its Effector Signaling

Author

Zhong, Shuangshuang, primary, Yin, Huijing, primary, Liao, Yueling, primary, Yao, Feng, primary, Li, Qi, primary, Zhang, Jie, primary, Jiao, Huike, primary, Zhao, Yongxu, primary, Xu, Dongliang, primary, Liu, Shuli, primary, Song, Hongyong, primary, Gao, Yong, primary, Liu, Jingyi, primary, Ma, Lina, primary, Pang, Zhi, primary, Yang, Ruixu, primary, Ding, Chengyi, primary, Sun, Beibei, primary, Lin, Xiaofeng, primary, Ye, Xiaofeng, primary, Guo, Wenzheng, primary, Han, Baohui, primary, Zhou, Binhua P., primary, Chin, Y. Eugene, primary, and Deng, Jiong, primary

Published
2023
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29. Supplementary Methods and References from Lung Tumor Suppressor GPRC5A Binds EGFR and Restrains Its Effector Signaling

Author

Zhong, Shuangshuang, primary, Yin, Huijing, primary, Liao, Yueling, primary, Yao, Feng, primary, Li, Qi, primary, Zhang, Jie, primary, Jiao, Huike, primary, Zhao, Yongxu, primary, Xu, Dongliang, primary, Liu, Shuli, primary, Song, Hongyong, primary, Gao, Yong, primary, Liu, Jingyi, primary, Ma, Lina, primary, Pang, Zhi, primary, Yang, Ruixu, primary, Ding, Chengyi, primary, Sun, Beibei, primary, Lin, Xiaofeng, primary, Ye, Xiaofeng, primary, Guo, Wenzheng, primary, Han, Baohui, primary, Zhou, Binhua P., primary, Chin, Y. Eugene, primary, and Deng, Jiong, primary

Published
2023
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31. Supplementary Figure 1 from RhoB Differentially Controls Akt Function in Tumor Cells and Stromal Endothelial Cells during Breast Tumorigenesis

Author

Kazerounian, Shiva, primary, Gerald, Damien, primary, Huang, Minzhou, primary, Chin, Y. Rebecca, primary, Udayakumar, Durga, primary, Zheng, Ningning, primary, O'Donnell, Rebekah K., primary, Perruzzi, Carole, primary, Mangiante, Lee, primary, Pourat, Jacob, primary, Phung, Thuy L., primary, Bravo-Nuevo, Arturo, primary, Shechter, Sharon, primary, McNamara, Stephanie, primary, DuHadaway, James B., primary, Kocher, Olivier N., primary, Brown, Lawrence F., primary, Toker, Alex, primary, Prendergast, George C., primary, and Benjamin, Laura E., primary

Published
2023
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32. Supplementary Methods and Materials from RhoB Differentially Controls Akt Function in Tumor Cells and Stromal Endothelial Cells during Breast Tumorigenesis

Author

Kazerounian, Shiva, primary, Gerald, Damien, primary, Huang, Minzhou, primary, Chin, Y. Rebecca, primary, Udayakumar, Durga, primary, Zheng, Ningning, primary, O'Donnell, Rebekah K., primary, Perruzzi, Carole, primary, Mangiante, Lee, primary, Pourat, Jacob, primary, Phung, Thuy L., primary, Bravo-Nuevo, Arturo, primary, Shechter, Sharon, primary, McNamara, Stephanie, primary, DuHadaway, James B., primary, Kocher, Olivier N., primary, Brown, Lawrence F., primary, Toker, Alex, primary, Prendergast, George C., primary, and Benjamin, Laura E., primary

Published
2023
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33. Supplementary Figure 3 from RhoB Differentially Controls Akt Function in Tumor Cells and Stromal Endothelial Cells during Breast Tumorigenesis

Author

Kazerounian, Shiva, primary, Gerald, Damien, primary, Huang, Minzhou, primary, Chin, Y. Rebecca, primary, Udayakumar, Durga, primary, Zheng, Ningning, primary, O'Donnell, Rebekah K., primary, Perruzzi, Carole, primary, Mangiante, Lee, primary, Pourat, Jacob, primary, Phung, Thuy L., primary, Bravo-Nuevo, Arturo, primary, Shechter, Sharon, primary, McNamara, Stephanie, primary, DuHadaway, James B., primary, Kocher, Olivier N., primary, Brown, Lawrence F., primary, Toker, Alex, primary, Prendergast, George C., primary, and Benjamin, Laura E., primary

Published
2023
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34. Senescent Stromal Cells Promote Cancer Resistance through SIRT1 Loss-Potentiated Overproduction of Small Extracellular Vesicles

Author

Han, Liu, primary, Long, Qilai, additional, Li, Shenjun, additional, Xu, Qixia, additional, Zhang, Boyi, additional, Dou, Xuefeng, additional, Qian, Min, additional, Jiramongkol, Yannasittha, additional, Guo, Jianming, additional, Cao, Liu, additional, Chin, Y. Eugene, additional, Lam, Eric W.-F., additional, Jiang, Jing, additional, and Sun, Yu, additional

Published
2020
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35. Acetylation within the N- and C-Terminal Domains of Src Regulates Distinct Roles of STAT3-Mediated Tumorigenesis

Author

Huang, Chao, primary, Zhang, Zhe, additional, Chen, Lihan, additional, Lee, Hank W., additional, Ayrapetov, Marina K., additional, Zhao, Ting C., additional, Hao, Yimei, additional, Gao, Jinsong, additional, Yang, Chunzhang, additional, Mehta, Gautam U., additional, Zhuang, Zhengping, additional, Zhang, Xiaoren, additional, Hu, Guohong, additional, and Chin, Y. Eugene, additional

Published
2018
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37. PtdIns(3,4,5)P3-Dependent Activation of the mTORC2 Kinase Complex

Author

Liu, Pengda, primary, Gan, Wenjian, additional, Chin, Y. Rebecca, additional, Ogura, Kohei, additional, Guo, Jianping, additional, Zhang, Jinfang, additional, Wang, Bin, additional, Blenis, John, additional, Cantley, Lewis C., additional, Toker, Alex, additional, Su, Bing, additional, and Wei, Wenyi, additional

Published
2015
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38. Lung Tumor Suppressor GPRC5A Binds EGFR and Restrains Its Effector Signaling

Author

Zhong, Shuangshuang, primary, Yin, Huijing, additional, Liao, Yueling, additional, Yao, Feng, additional, Li, Qi, additional, Zhang, Jie, additional, Jiao, Huike, additional, Zhao, Yongxu, additional, Xu, Dongliang, additional, Liu, Shuli, additional, Song, Hongyong, additional, Gao, Yong, additional, Liu, Jingyi, additional, Ma, Lina, additional, Pang, Zhi, additional, Yang, Ruixu, additional, Ding, Chengyi, additional, Sun, Beibei, additional, Lin, Xiaofeng, additional, Ye, Xiaofeng, additional, Guo, Wenzheng, additional, Han, Baohui, additional, Zhou, Binhua P., additional, Chin, Y. Eugene, additional, and Deng, Jiong, additional

Published
2015
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39. Snail Recruits Ring1B to Mediate Transcriptional Repression and Cell Migration in Pancreatic Cancer Cells

Author

Chen, Jiangzhi, primary, Xu, Hong, additional, Zou, Xiuqun, additional, Wang, Jiamin, additional, Zhu, Yi, additional, Chen, Hao, additional, Shen, Baiyong, additional, Deng, Xiaxing, additional, Zhou, Aiwu, additional, Chin, Y. Eugene, additional, Rauscher, Frank J., additional, Peng, Chenghong, additional, and Hou, Zhaoyuan, additional

Published
2014
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42. RhoB Differentially Controls Akt Function in Tumor Cells and Stromal Endothelial Cells during Breast Tumorigenesis

Author

Kazerounian, Shiva, primary, Gerald, Damien, additional, Huang, Minzhou, additional, Chin, Y. Rebecca, additional, Udayakumar, Durga, additional, Zheng, Ningning, additional, O'Donnell, Rebekah K., additional, Perruzzi, Carole, additional, Mangiante, Lee, additional, Pourat, Jacob, additional, Phung, Thuy L., additional, Bravo-Nuevo, Arturo, additional, Shechter, Sharon, additional, McNamara, Stephanie, additional, DuHadaway, James B., additional, Kocher, Olivier N., additional, Brown, Lawrence F., additional, Toker, Alex, additional, Prendergast, George C., additional, and Benjamin, Laura E., additional

Published
2013
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43. 3-Phosphoinositide–Dependent Kinase 1 Potentiates Upstream Lesions on the Phosphatidylinositol 3-Kinase Pathway in Breast Carcinoma

Author

Maurer, Matthew, primary, Su, Tao, additional, Saal, Lao H., additional, Koujak, Susan, additional, Hopkins, Benjamin D., additional, Barkley, Christina R., additional, Wu, Jiaping, additional, Nandula, Subhadra, additional, Dutta, Bhaskar, additional, Xie, Yuli, additional, Chin, Y. Rebecca, additional, Kim, Da-In, additional, Ferris, Jennifer S., additional, Gruvberger-Saal, Sofia K., additional, Laakso, Mervi, additional, Wang, Xiaomei, additional, Memeo, Lorenzo, additional, Rojtman, Albert, additional, Matos, Tulio, additional, Yu, Jennifer S., additional, Cordon-Cardo, Carlos, additional, Isola, Jorma, additional, Terry, Mary Beth, additional, Toker, Alex, additional, Mills, Gordon B., additional, Zhao, Jean J., additional, Murty, Vundavalli V.V.S., additional, Hibshoosh, Hanina, additional, and Parsons, Ramon, additional

Published
2009
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45. Reassessment of Id1 Protein Expression in Human Mammary, Prostate, and Bladder Cancers Using a Monospecific Rabbit Monoclonal Anti-Id1 Antibody

Author

Paola de Candia, Yvette Chin, John Chen, William L. Gerald, Yuntao Zhao, Jonathan Perk, Edi Brogi, Ignacio Gil-Bazo, Yaohuang Ke, Hikmat Al-Ahmadie, Wai Cheong, Robert Benezra, Shirley Chao, Perk, J., Gil-Bazo, I., Chin, Y., De Candia, P., Chen, J. J. S., Zhao, Y., Chao, S., Cheong, W., Ke, Y., Al-Ahmadie, H., Gerald, W. L., Brogi, E., and Benezra, R.

Subjects
Inhibitor of Differentiation Protein 1, Male, PCA3, Cancer Research, Cell type, Pathology, medicine.medical_specialty, Mammary gland, Mammary Neoplasms, Animal, Prostate cancer, Prostate, Neoplasms, medicine, Animals, Humans, Bladder cancer, biology, Antibodies, Monoclonal, Endothelial Cells, Prostatic Neoplasms, Epithelial Cells, medicine.disease, Immunohistochemistry, medicine.anatomical_structure, Urinary Bladder Neoplasms, Oncology, Monoclonal, Cancer research, biology.protein, Female, Rabbits, Antibody
Abstract

Id proteins are a class of dominant-negative antagonists of helix-loop-helix transcription factors and have been shown to control differentiation of a variety of cell types in diverse organisms. Although the importance of Id1 in tumor endothelial cells is well established, the expression and role of the Id1 protein in human cancer cells is controversial. To explore this issue, we developed and characterized a highly specific rabbit monoclonal antibody against Id1 to assess its expression in human breast, prostate, and bladder malignancies. Our results show that in usual types of human mammary carcinomas, the Id1 protein is expressed exclusively in the endothelium. Interestingly, we detected nuclear expression of the Id1 protein in the tumor cells in 10 of 45 cases of poorly differentiated and highly aggressive carcinoma with metaplastic morphology. Similarly, only 1 of 30 prostate cancer samples showed Id1-positive tumor cells, whereas in almost all, endothelial cells showed high Id1 expression. Intriguingly, whereas normal prostate glands do not show any Id1 protein expression, basal layer cells of benign prostate glands in proximity to tumors expressed high levels of the Id1 protein. In contrast to the lack of Id1 expression in the usual types of mammary and prostate cancers, the majority of transitional cell bladder tumors showed Id1 protein expression in both tumor and endothelial cells. These results suggest that further refinement of Id1 expression patterns in a variety of tumor types will be necessary to identify and study the functional roles played by Id1 in human neoplastic processes. (Cancer Res 2006; 66(22): 10870-7)

Published
2006
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