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Your search keyword '"Putrescine cerebrospinal fluid"' showing total 2 results
Start Over Descriptor "Putrescine cerebrospinal fluid" Publisher american association for cancer research
2 results on '"Putrescine cerebrospinal fluid"'

1. The relationship of polyamines in cerebrospinal fluid to the presence of central nervous system tumors.

Author

Marton LJ, Heby O, Levin VA, Lubich WP, Crafts DC, and Wilson CB

Subjects
Adenoma cerebrospinal fluid, Astrocytoma cerebrospinal fluid, Central Nervous System Diseases cerebrospinal fluid, Glioma cerebrospinal fluid, Humans, Medulloblastoma cerebrospinal fluid, Meningioma cerebrospinal fluid, Pituitary Neoplasms cerebrospinal fluid, Putrescine cerebrospinal fluid, Spermidine cerebrospinal fluid, Spermine cerebrospinal fluid, Brain Neoplasms cerebrospinal fluid, Polyamines cerebrospinal fluid
Abstract

Cerebrospinal fluid (CSF) polyamine concentrations were assayed in patients with and without central nervous system tumors, using a high-pressure liquid chromatographic technique. Definite elevations were found in the CFS polyamine concentrations of patients with untreated malignant central nervous system tumors when compared with those concentrations observed in the CSF of patients without neoplasia. Patients undergoing successful tumor therapy for malignant central nervous system tumors showed CSF polyamine concentrations that closely approximated the concentrations found in the CSF of patients without tumor.

Published
1976

2. Predictive value of cerebrospinal fluid polyamines in medulloblastoma.

Author

Marton LJ, Edwards MS, Levin VA, Lubich WP, and Wilson CB

Subjects
Adolescent, Adult, Brain Neoplasms diagnosis, Child, False Negative Reactions, Female, Humans, Male, Medulloblastoma diagnosis, Prognosis, Brain Neoplasms cerebrospinal fluid, Medulloblastoma cerebrospinal fluid, Putrescine cerebrospinal fluid, Spermidine cerebrospinal fluid
Abstract

Seventy-five cerebrospinal fluid polyamine determinations were evaluated in 16 patients with medulloblastoma. Parameters utilized in evaluating patient status for correlation with the polyamine concentrations were neurological examination, computerized tomography, radionuclide scan, myelography, and cerebrospinal fluid cytology. Fifteen of the 16 patients showed absolute correlation with the eventual clinical picture. One determination on one patient resulted in a false negative. No false positives have been observed to date.

Published
1979

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