1. Circadian sleep propensity and alcohol interaction at the wheel
- Author
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Claudio Campus, Sergio Garbarino, Giuseppe Plazzi, Pierre Philip, Elisa Morrone, Fabrizio De Carli, Lino Nobili, Garbarino, Sergio, Nobili, Lino, Philip, Pierre, Plazzi, Giuseppe, Campus, Claudio, Morrone, Elisa, and De Carli, Fabrizio
- Subjects
Pulmonary and Respiratory Medicine ,medicine.medical_specialty ,Automobile Driving ,Sleepiness ,Alcohol Drinking ,Poison control ,Context (language use) ,Comorbidity ,Logistic regression ,Sleep medicine ,Crash risk ,Transport engineering ,Alcohol consumption ,Driving ,Accidents, Traffic ,Circadian Rhythm ,Humans ,Italy ,Sleep Deprivation ,Blood Alcohol Content ,Neurology ,Neurology (clinical) ,03 medical and health sciences ,0302 clinical medicine ,medicine ,Traffic ,0501 psychology and cognitive sciences ,030212 general & internal medicine ,Circadian rhythm ,050107 human factors ,Sleepine ,business.industry ,05 social sciences ,Scientific Investigations ,Sleep deprivation ,Relative risk ,Accidents ,Blood alcohol content ,medicine.symptom ,business ,human activities ,Demography - Abstract
OBJECTIVES: The study was aimed at estimating the effect of alcohol consumption, time of day, and their interaction on traffic crashes in a real regional context. METHODS: Blood alcohol concentration (BAC) data were collected from drivers involved in traffic accidents during one year in an Italian region and in a control group of drivers over the same road network. Mean circadian sleep propensity was estimated from a previous study as function of time of day. Accident risk was analyzed by logistic regression as function of BAC and circadian sleep propensity. RESULTS: BAC values greater than zero were found in 72.0% of the drivers involved in crashes and in 40.4% of the controls. Among the former 23.6% of the drivers exceeded the BAC legal threshold of 0.05 g/dL, while illegal values were found in 10.4% of the controls. The relative risk showed a significant increase with both BAC and circadian sleep propensity (as estimated from time of day) and their interaction was significant. CONCLUSIONS: Due to the significant interaction, even low BAC levels strongly increased accident risk when associated with high sleep propensity.Copyright © 2016 American Academy of Sleep Medicine. All rights reserved. Language: en
- Published
- 2016