1. The role of bacterial culture by bronchoscopy in patients with lung cancer: a prospective study
- Author
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David Shitrit, Matthew Koslow, Alexander Guber, Alona Matveychuk, Gali Epstein Shochet, and Lilach Israeli-Shani
- Subjects
0301 basic medicine ,Pulmonary and Respiratory Medicine ,medicine.medical_specialty ,Microbiological culture ,Malignancy ,medicine.disease_cause ,Gastroenterology ,03 medical and health sciences ,0302 clinical medicine ,Bronchoscopy ,Internal medicine ,medicine ,Prospective cohort study ,Lung cancer ,Suspicious for Malignancy ,Lung ,medicine.diagnostic_test ,business.industry ,030208 emergency & critical care medicine ,medicine.disease ,Surgery ,030104 developmental biology ,medicine.anatomical_structure ,Staphylococcus aureus ,Original Article ,business - Abstract
Background: Patients with lung cancer undergoing surgical and medical treatment are at increased risk for pulmonary complications. The importance of routine broncoscopy procedure in populations with lung cancer has rarely been defined. We aimed to determine the growth of potentially pathogenic microorganisms (PPM) among patients evaluated by bronchoscopy for lung cancer. Methods: This prospective study included 155 consecutive patients with lung mass or radiologic findings suspicious for malignancy. Baseline demographic, clinical and radiologic features were collected. Clinical features of infection were compared to microbiologic and histologic results. Results: The bacterial spectrum of lung cancer patients was similar to those without malignancy. The most frequently isolated organisms were Pseudomonas sp . and Staphylococcus aureus . Among all patients, bronchial bacterial positive PPM growth was noted in 30% (46/155). The significant PPM growth rate was three-fold higher among those with clinical signs of infection (P Conclusions: Bronchoscopic evaluations should include bacterial cultures for direct targeted antibiotic therapy only in the symptomatic patients.
- Published
- 2017