1. Clinical update on central hypersomnias
- Author
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Laura Pérez-Carbonell and Guy D. Leschziner
- Subjects
Pulmonary and Respiratory Medicine ,medicine.medical_specialty ,business.industry ,Excessive daytime sleepiness ,Treatment options ,Review Article ,medicine.disease ,03 medical and health sciences ,0302 clinical medicine ,030228 respiratory system ,medicine ,medicine.symptom ,Intensive care medicine ,Psychiatry ,business ,030217 neurology & neurosurgery ,Narcolepsy - Abstract
The central hypersomnias encompass a range of conditions causing persisting or intermittent excessive daytime sleepiness (EDS). These conditions therefore present not infrequently in general clinical sleep practice, and remain in the differential for patients presenting with sleepiness. Our understanding of the pathophysiology, diagnosis and management of these conditions has progressed significantly over recent years, and in this article we review this group of disorders, focussing in particular on recent changes in classification and diagnosis, pathophysiological advances, and novel treatment options.
- Published
- 2018
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