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Progressive increase in the proportion of elderly patients in the population of many countries actualizes the issues of preserving physical and mental health, working capacity and quality of life of retirees. As a part of preventive geriatric rehabilitation, ‘the Active Longevity’ program has been operating in many cities of Russia over the past three years, one of the aspects of the program is the involvement of elderly patients in active life, including an increase in physical activity. This study included 744 patients who attended face‑to‑face physical training sessions. According to the results of the survey, 41% of pensioners noted an increase of daily physical activity, 94% reported an improvement in health and mood, the level of total blood cholesterol decreased. Almost all patients, both with and without clinical and subclinical manifestations of anxiety and depression, reported a good and very good mood immediately after exercise. Increasing physical activity in elderly patients improves the quality of life and prolongs its duration, and is also an effective method of non‑drug treatment of anxiety‑depressive disorders.

At the end of 2019, a new coronavirus (SARS-CoV-2) was discovered in China, causing the coronavirus infection COVID-19.The ongoing COVID-19 pandemic poses a major challenge tohealth systems around the world. There is still little informationon how infection affects liver function and the significanceof pre-existing liver disease as a risk factor for infection andsevere COVID-19. In addition, some drugs used to treat thenew coronavirus infection are hepatotoxic. In this article, weanalyze data on the impact of COVID-19 on liver function, aswell as on the course and outcome of COVID-19 in patients withliver disease, including hepatocellular carcinoma, or those onimmunosuppressive therapy after liver transplantation.