1. [Acute cytomegalovirus infection-associated hemophagocytic syndrome in a patient treated with azathioprine].
- Author
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Kullmann T, Kárász T, Gartner B, Issekutz A, Oláh A, and Rácz I
- Subjects
- Antiviral Agents administration & dosage, Azathioprine administration & dosage, Colitis, Ulcerative pathology, Colonoscopy, Combined Modality Therapy, Cytomegalovirus Infections immunology, Febrile Neutropenia therapy, Febrile Neutropenia virology, Female, Ganciclovir administration & dosage, Humans, Immunosuppressive Agents administration & dosage, Infusions, Intravenous, Lymphohistiocytosis, Hemophagocytic drug therapy, Treatment Outcome, Young Adult, Azathioprine adverse effects, Colitis, Ulcerative drug therapy, Critical Care methods, Cytomegalovirus Infections complications, Immunosuppressive Agents adverse effects, Lymphohistiocytosis, Hemophagocytic therapy, Lymphohistiocytosis, Hemophagocytic virology
- Abstract
The authors present the case of a 21-year-old woman with ulcerative colitis. Azathioprine treatment was complicated with pancytopenia and septic shock. Acute cytomegalovirus infection related to the immunosuppressive therapy, resulting in hemophagocytosis syndrome and neutropenic fever was diagnosed. Recovery was achieved by the administration of parenteral ganciclovir, broad spectrum antibiotic and complex intensive care.
- Published
- 2013
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