1. Role of Leukoreduction of Packed Red Blood Cell Units in Trauma Patients: A Review
- Author
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Alex L. Chang, Young Kim, Timothy A. Pritts, and Brent T. Xia
- Subjects
medicine.medical_specialty ,Erythrocyte transfusion ,education.field_of_study ,Blood transfusion ,Standard of care ,business.industry ,medicine.medical_treatment ,Population ,030204 cardiovascular system & hematology ,3. Good health ,03 medical and health sciences ,Red blood cell ,0302 clinical medicine ,medicine.anatomical_structure ,Leukoreduction ,Hemorrhagic shock ,medicine ,030212 general & internal medicine ,Leukocyte depletion ,Intensive care medicine ,business ,education - Abstract
Hemorrhagic shock is a leading cause of mortality within the trauma population, and blood transfusion is the standard of care. Leukoreduction filters remove donor leukocytes prior to transfusion of blood products. While the benefits of leukocyte depletion are well documented in scientific literature, these benefits do not translate directly to the clinical setting. This review summarizes current research regarding leukoreduction in the clinical arena, as well as studies performed exclusively in the trauma population.
- Published
- 2016
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