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The leaves of Lantana camara L. (Verbenaceae) were subjected to hydrodistillation, and the essential oil extracted was examined with respect to chemical composition, antibacterial and antibiotic modifying activity by gaseous contact. Among the 25 identified components, bicyclogermacrene (26.1%), β-caryophyllene (24.4%), germacrene D (19.2%) and valecene (12.0%) were the main constituents. The essential oil volatile constituents inhibited the growth of Staphylococcus aureus and Pseudomonas aeruginosa with MIC of 1 and > 1 mg/L, respectively. The activity of the antibiotic amikacin was increased by 65% against S. aureus and P. aeruginosa after contact with the volatile components. [ABSTRACT FROM AUTHOR]

The leaves of Lantana montevidensis Briq. (Verbenaceae) were subjected to hydrodistillation, and the essential oil extracted was examined with respect to chemical composition, antibacterial and antibiotic modifying activity by gaseous contact. Among the 19 identified components, β-caryophyllene (31.50%), germacrene D (27.50%) and bicyclogermacrene (13.93%) were the main constituents. The essential oil volatile constituents inhibited the growth of Staphylococcus aureus and Pseudomonas aeruginosa with a MID o 0.25 and > 1 mg/L, respectively. The activity of the antibiotics gentamicin and amikacin was reinforced against S. aureus and P. aeruginosa (with a 102% of amikacin activity against P. aeruginosa) after contact with the volatile components, showing that this oil influences the activity of the antibiotic and may be used as an adjuvant in the antibiotic therapy of respiratory tract bacterial pathogens. [ABSTRACT FROM AUTHOR]

To verify the composition variation of its essential oil along 24 hours, leaves of Lantana camara Linn. of medicinal plant collection of the Department of Chemical Biology of URCA-Crato-CE, were collected every three hours during one day (of the 07:00 to 19:00 h) in April, 2008. The leaves had its oil extracted by hydro-distillation in Clevenger apparatus during three hours with two repetitions. The chemical composition analysis of the extracted essential oils was carried out in gas chromatography/mass spectroscopy. The phytochemical profile of the essential oils presented significant difference in function of the harvest. The seven most abundant were: germacrene D (24.50-6.15%), biciclogermacrene (33.32-14.27%), spathulenol (25.04-1.06%), eremophilene (20.64-1.93%), valecene (33.70-0.84%), viridiflorene (19.46%) and 1,10-di-epi-cubenol (27.93-21.32). The different result found here indicates the existence of different chemotypes of L. camara. [ABSTRACT FROM AUTHOR]