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The genus Kadsura is an important part of traditional Chinese medicine, it has the functions of promoting wind, eliminating dampness, activating blood circulation. Modern pharmacological studies have shown that lignans are one of the main components to possess these medicinal effects. This review aimed to provide a systematic summary on the traditional use, phytochemistry, pharmacology, toxicology and other aspects of lignans in genus Kadsura. In this paper, we collected the relevant literature on Kadsura lignans from 1973 to the present, and isolated more than 337 lignans from this genus, including dibenzocyclooctadienes, aryltetralins, tetrahydrofurans, diarylbutanes, 7,8-secolignans, bisepoxylignans, neolignans, seco-dibenzocyclooctadienes, sesquilignan and coumarin-containing lignan. Previous pharmacological studies have shown that lignans of the genus Kadsura have antitumor, anti-inflammatory, antibacterial, anti-HIV, anti-platelet aggregation, immunomodulatory and antioxidant effects. In clinical practice, it is commonly used to treat Alzheimer's disease, inflammation and insomnia. Kadsura is an important part of the field of Chinese medicine and is widely used in traditional medicine. However, further clarification of its active ingredients and mechanism of action and the establishment of a complete quality standard system are needed in order to provide a scientific basis for in-depth studies of this genus. [ABSTRACT FROM AUTHOR]

The genus Kadsura is a commonly used herb in Chinese folklore, with sedative, hypnotic and beneficial effects, mainly for the treatment of rheumatoid arthritis, insomnia and other conditions. Modern pharmacological studies have shown that triterpenoids are one of the main components to possess these medicinal effects. In addition, triterpenoids in genus Kadsura also exhibited anti-tumor, cholesterol synthesis inhibition, anti-HIV, antioxidant and hepatoprotective activities. At present, there are few literatures reported on the triterpenoids in this genus. Therefore, the purpose of this paper is to review the triterpenoids in the genus Kadsura and their pharmacological activities, introduce the research progress on their germplasm resources, clinical applications and developmental applications, and provide references for further research and development of the plant resources of this genus. [ABSTRACT FROM AUTHOR]