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Abstract: Recent developments in multi-scale modelling, based on atomic scale calculations, are leading to a growing conviction that modelling will soon be used to design material components for nuclear reactors. In this article we discuss this assumption on the basis of the relationship between experimental studies and theoretical calculations of the microstructural evolution of materials under irradiation. In the first part of the paper, the available numerical models for long term microstructural evolutions are briefly reviewed. The experimental methods are presented in a second part. In the third part, several examples of fruitful relationships between modelling and experiments are discussed. To cite this article: A. Barbu, C. R. Physique 9 (2008). [Copyright &y& Elsevier]

Abstract: Multi-scale models based on computational homogenisation are nowadays developed for the simulation of complex material behaviour. The use of homogenisation techniques on finite-sized representative volume elements in the presence of quasi-brittle damage may lead to the presence of snap-backs in the macroscopic material response. A methodology to simulate this type of response in the multi-scale technique is proposed, based on the control of the dissipation at the mesoscopic scale. To cite this article: T.J. Massart et al., C. R. Mecanique 333 (2005). [Copyright &y& Elsevier]