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1. Generation of an antibody that recognizes Plasmodium chabaudi cysteine protease (chabaupain-1) in both sexual and asexual parasite life cycle and evaluation of chabaupain-1 vaccine potential.

Author

Armada, Ana, Gazarini, Marcos L., Gonçalves, Lídia M., Antunes, Sandra, Custódio, Ana, Rodrigues, Armanda, Almeida, António J., Silveira, Henrique, Rosário, Virgílio do, Santos-Gomes, Gabriela, and Domingos, Ana

Subjects
*ANTIBODY formation, *PLASMODIUM, *CYSTEINE proteinases, *PARASITE life cycles, *MALARIA, *LABORATORY mice, *IMMUNE response
Abstract

Highlights: [•] Localization of P. chabaudi CP-1 in malaria stages is described for the first time. [•] Mice immunization with PcrCP-1 reduces parasitaemia. [•] PcrCP-1 confers protective immune response to P. chabaudi infection. [Copyright &y& Elsevier]

Published
2013
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