A well known result of Forstnerić [15] states that most real-analytic strictly pseudoconvex hypersurfaces in complex space are not holomorphically embeddable into spheres of higher dimension. A more recent result by Forstnerić [16] states even more: most real-analytic hypersurfaces do not admit a holomorphic embedding even into a merely algebraic hypersurface of higher dimension, in particular, a hyperquadric. We emphasize that both cited theorems are proved by showing that the set of embeddable hypersurfaces is a set of first Baire category. At the same time, the classical theorem of Webster [30] asserts that every real-algebraic Levi-nondegenerate hypersurface admits a transverse holomorphic embedding into a nondegenerate real hyperquadric in complex space. In this paper, we provide effective results on the non-embeddability of real-analytic hypersurfaces into a hyperquadric. We show that, under the codimension restriction N ≤ 2 n , the defining functions φ ( z , z ¯ , u ) of all real-analytic hypersurfaces M = { v = φ ( z , z ¯ , u ) } ⊂ C n + 1 containing Levi-nondegenerate points and locally transversally holomorphically embeddable into some hyperquadric Q ⊂ C N + 1 satisfy an universal algebraic partial differential equation D ( φ ) = 0 , where the algebraic-differential operator D = D ( n , N ) depends on n ≥ 1 , n < N ≤ 2 n only. To the best of our knowledge, this is the first effective result characterizing real-analytic hypersurfaces embeddable into a hyperquadric of higher dimension. As an application, we show that for every n , N as above there exists μ = μ ( n , N ) such that a Zariski generic real-analytic hypersurface M ⊂ C n + 1 of degree ≥ μ is not transversally holomorphically embeddable into any hyperquadric Q ⊂ C N + 1 . We also provide an explicit upper bound for μ in terms of n , N . To the best of our knowledge, this gives the first effective lower bound for the CR-complexity of a Zariski generic real-algebraic hypersurface in complex space of a fixed degree. [ABSTRACT FROM AUTHOR]