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Start Over Author "Boele, Joost" Publisher academic press inc.
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1. Systemic identification of estrogen-regulated genes in breast cancer cells through cap analysis of gene expression mapping.

Author

Yamaga, Ryonosuke, Ikeda, Kazuhiro, Boele, Joost, Horie-Inoue, Kuniko, Takayama, Ken-ichi, Urano, Tomohiko, Kaida, Kaoru, Carninci, Piero, Kawai, Jun, Hayashizaki, Yoshihide, Ouchi, Yasuyoshi, de Hoon, Michiel, and Inoue, Satoshi

Subjects
*BREAST cancer, *ESTROGEN receptors, *GENETIC regulation, *CANCER cells, *GENE expression, *GENE mapping, *NUCLEOTIDE sequence
Abstract

Highlights: [•] Cap analysis of gene expression sequencing is performed in breast cancer MCF-7 cells. [•] The method identifies 15 CAGE tag clusters close to estrogen receptor binding sites. [•] RAMP3, ISOC1 and GPRC5C are estrogen-regulated genes with those CAGE tag clusters. [•] RAMP3, ISOC1 and GPRC5C will regulate growth/migration of MCF-7 cells. [•] CAGE sequencing is useful for global identification of estrogen-regulated promoters. [ABSTRACT FROM AUTHOR]

Published
2014
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