1. Small cell carcinoma of the ovary hypercalcemic type (SCCOHT): Comprehensive management of a newly diagnosed young adult.
- Author
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Pressey JG, Dandoy CE, Pater LE, Sroga Rios J, Sisson R, Dasgupta R, and Szabo S
- Subjects
- Adult, Antineoplastic Combined Chemotherapy Protocols therapeutic use, Carcinoma, Small Cell genetics, DNA Helicases genetics, Female, Hematopoietic Stem Cell Transplantation, Humans, Hypercalcemia diagnosis, Hypercalcemia genetics, Hypercalcemia therapy, Hyperthermic Intraperitoneal Chemotherapy, Nuclear Proteins genetics, Ovarian Neoplasms genetics, Transcription Factors genetics, Carcinoma, Small Cell diagnosis, Carcinoma, Small Cell therapy, Ovarian Neoplasms diagnosis, Ovarian Neoplasms therapy
- Abstract
SCCOHT is an aggressive malignancy linked to alterations of SMARCA4. We describe the diagnosis and therapy of a 32 year old who received multi-agent chemotherapy and underwent a second look operation with HIPEC followed by high-dose chemotherapy with stem cell transplant. Supportive care, oncofertility, and genetic counseling are described., Competing Interests: Declaration of competing interest None., (Copyright © 2020. Published by Elsevier Inc.)
- Published
- 2020
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