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As nations alike struggle to diversify and secure their power portfolios, geothermal energy, the essentially limitless heat emanating from the earth itself, is being harnessed at an unprecedented rate. For the last 25 years, engineers around the world tasked with taming this raw power have used Geothermal Reservoir Engineering as both a training manual and a professional reference. This long-awaited second edition of Geothermal Reservoir Engineering is a practical guide to the issues and tasks geothermal engineers encounter in the course of their daily jobs. The book focuses particularly on the evaluation of potential sites and provides detailed guidance on the field management of the power plants built on them. With over 100 pages of new material informed by the breakthroughs of the last 25 years, Geothermal Reservoir Engineering remains the only training tool and professional reference dedicated to advising both new and experienced geothermal reservoir engineers. - The only resource available to help geothermal professionals make smart choices in field site selection and reservoir management - Practical focus eschews theory and basics- getting right to the heart of the important issues encountered in the field - Updates include coverage of advances in EGS (enhanced geothermal systems), well stimulation, well modeling, extensive field histories and preparing data for reservoir simulation - Case studies provide cautionary tales and best practices that can only be imparted by a seasoned expert

This reference is a volume in the Handbook of Physiology, co-published with The American Physiological Society. Growth in knowledge about the microcirculation has been explosive with the field becoming fragmented into numerous subdisciplines and subspecialties. This volume pulls all of the critical information into one volume. - Meticulously edited and reviewed. Benefit: Provides investigators a unique tool to explore the significance of their findings in the context of other aspects of the microcirculation. In this way, the updated edition has a direct role in helping to develop new pathways of research and scholarship - Highlights the explosive growth in knowledge about the microcirculation including the biology of nitric oxide synthase (NOS), endothelial cell signaling, angiogenesis, cell adhesion molecules, lymphocyte trafficking, ion channels and receptors, and propagated vasomotor responses. Benefit: Microcirculatory biology has become fragmented into numerous sub-disciplines and subspecialties, and these reference reintegrates the information in one volume

This superbly illustrated work provides short accounts of the lives and scientific contributions of all of the major pioneers of Tropical Medicine. Largely biographical, the stories discussed enlighten a new generation of scientists to the advances made by their predecessors. Written by Gordon Cook, contributor to the hugely popular Manson's Tropical Diseases, this report discusses the pioneers themselves and offers a global accounting of their experiences at the onset of the discipline.

This book describes the major achievements and discoveries relevant to bacterial protein toxins since the turn of the new century illustrated by the discovery of more than fifty novel toxins (many of them identified through genome screening). The establishment of the three-dimensional crystal structure of more than 20 toxins during the same period offers deeper knowledge of structure-activity relationships and provides a framework to understand how toxins recognize receptors, penetrate membranes and interact with and modify intracellular substrates. - Edited by two of the most highly regarded experts in the field from the Institut Pasteur, France - 14 brand new chapters dedicated to coverage of historical and general aspects of toxinology - Includes the major toxins of both basic and clinical interest are described in depth - Details applied aspects of toxins such as therapy, vaccinology, and toolkits in cell biology - Evolutionary and functional aspects of bacterial toxins evaluated and summarized - Toxin applications in cell biology presented - Therapy (cancer therapy, dystonias) discussed - Vaccines (native and genetically engineered vaccines) featured - Toxins discussed as biological weapons, comprising chapters on anthrax, diphtheria, ricin etc.

The acclaimed International Review of Cytology series presents current advances and reviews in cell biology, both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. Contributors to this volume include Giacomo Azzali, Annalena Civinini, Isabelle Creveaux, Bernard Dastugue, Arnold De Loof, Robert Didier, Steven K. Fisher, Nicolas Goncalves-Mendex, Geoffrey P. Lewis, Annie Meiniel, Robert Meiniel, Tom Meeusen, Inge Mertens, Valentina Patrizia Gallo, and Liliane Schoofs.

Challenging and provocative overviews are presented in Volume 40 of Current Topics in Membranes. Topics on cell lipids vary from basic themes such as biosynthesis and membrane distribution to the role of lipids in intracellular signaling and membrane flow. This single volume also highlights the roles of lipids in eukaryotic cells and discusses organization of lipids in microdomains.

The Biology of ß-Lactam Antibiotics

Advances in Applied Microbiology

Advances in Applied Microbiology

International Review of Cytology presents current advances and comprehensive reviews in cell biology-both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research.