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Handbook of Plant-Based Food and Drinks Design discusses conventional and emerging technologies for plant-based ingredient improvement (yield, nutritional composition and functional properties) while considering food safety, sustainability, and social impact to explore current and potential markets through research and innovation. Divided in 7 sections, the book covers Plant sources for functional ingredients, Processing plant-based sources, Plant-based food design to replace/mimic animal food, Innovation in plant-based food, The promise of parity, Safety and regulations of plant-based foods, Social, environmental, and economic impact, and more. Written by a team of experts in the field, this book can be a good support for researchers and scientists working with plant-based food, drinks, and market trends. - Brings a critical overview about the health-beneficial compounds of plant-based sources - Offers guidelines on how to formulate plant-based food or a food alternative - Discusses the transition towards more plant-based diets on nutrition, economy climate change, health, and sustainability

Feed additives (natural or synthetic) are formulations added to livestock rations to improve growth rates, reproductive and productive traits, feed efficiency, ruminal fermentation profiles, methane mitigation, digestion and absorption of nutrients, immunity, and overall health of the animal. Organic Feed Additives for Livestock will focus on the beneficial effects of organic feed additives and on food animals, including ruminants, poultry, fish, and more. It will also explore how these feed additives can benefit food animal production, reproduction, and health. Each chapter will cover the significance of an organic feed supplement, especially as an alternative to synthetic growth promoters, with topics including medicinal plants, cold pressed and essential oils, natural antioxidants, emulsifiers, acidifiers and organic acids, fibrolytic enzymes, organic minerals, probiotics, macro- and microalgae, organic nanoparticles, yeast and its derivatives, and bee pollen. Contributed by a range of livestock and aquaculture specialists from around the world, this book takes a holistic approach to explore how organic additives offer an efficient strategy to improve livestock productivity and health. This reference is an excellent resource for researchers and graduate students interested in animal agriculture, as well as veterinarians, animal nutritionists and breeders, and other livestock specialists. It will allow experts to stay up to date on organic options for livestock and serve as a starting point in generating new research ideas. - Summarizes the latest developments in organic livestock nutrition - Describes the importance of organic and natural feed supplements in production of the healthy food for livestock - Contributed by a range of livestock and aquaculture specialists all around the world - Offers natural and nutritionally beneficial alternatives to antibiotics and synthetic growth promoters

Encyclopedia of Biodiversity, Third Edition, Seven Volume Set provides a coherent, synthetic and comprehensive overview of the field, bringing together contributions from over 400 expert academics and practitioners. The book brings together the dimensions of biodiversity and examines the services it provides and measures to protect it. Major themes include the evolution of biodiversity, systems for classifying and defining biodiversity, ecological patterns and theories of biodiversity, and an assessment of contemporary patterns and trends in biodiversity. The entire work is reviewed and updated, including new chapters on topics which have come to the forefront since the publication of the previous edition. The science of biodiversity has become the science of our future. It is an interdisciplinary field spanning areas of both physical and life sciences. Our awareness of the loss of biodiversity has brought a long overdue appreciation of the magnitude of this loss and a determination to develop the tools to protect our future. One important feature of the new edition will be updated information on the growing biodiversity crisis. - Offers a one-stop shop with access to a wealth of information currently available only in scattered or non-technical sources - Written by renowned academics and practitioners working in different research areas, providing an all-round depiction of the field - Guides readers though the topic, and is written to be accessible to a general, educated audience and scientists and practitioners looking for an overview - Presents the latest release in a resource used by a wide range of scientists

Innovation of Food Products in the Halal Supply Chain Worldwide covers the fundamentals and food guidelines of halal food production. Unlike other texts on the halal food market and halal certification, this book promotes halal product innovation by presenting exciting newly developed ingredients that are substitutions of non-halal ingredients with halal alternatives, such as lard substituted with modified vegetable fats, pig with halal goat/beef/camel/fish gelatin/collagen, alternative meat substitute or even additives. Innovations in halal processing technologies cover the latest techniques in halal production and authentication, halal tracking/traceability in halal transport and logistics, a vast area at the end of a supply chain. All chapters are written by acknowledged experts in their field, thus the book brings together the top researchers in this essential topic of importance to a huge percentage of the world's population. - Helps readers understand the advancement of available halal substitutes and replacers - Offers tools to enhances product sustainability and food security through innovation - Fosters innovation in food science with alternative halal ingredients

Immunological Methods in Microbiology, Volume 47 in the Methods in Microbiology series, highlights new advances in the field, with this new volume presenting interesting chapters on Immunological Techniques in the Clinical laboratory, Immunologic Diagnosis of HIV and Opportunistic Infections, Combining Antigen Detection and Serology for the Diagnosis of Selected Infectious Diseases, Immunologic Detection of Lyme Disease and Related Borrelioses, Immunodetection of Bacteria Causing Brucellosis, Immunological Diagnostic Techniques Used to Identify and Type Pasteurella, Immunological Tests for Diarrhea caused by Diarrheagenic Escherichia coli Targeting Their Main Virulence Factors, and much more. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in the Methods in Microbiology series - Includes the latest information on Immunological Methods in Microbiology

This new fifth edition of Information Resources in Toxicology offers a consolidated entry portal for the study, research, and practice of toxicology. Both volumes represents a unique, wide-ranging, curated, international, annotated bibliography, and directory of major resources in toxicology and allied fields such as environmental and occupational health, chemical safety, and risk assessment. The editors and authors are among the leaders of the profession sharing their cumulative wisdom in toxicology's subdisciplines. This edition keeps pace with the digital world in directing and linking readers to relevant websites and other online tools.Due to the increasing size of the hardcopy publication, the current edition has been divided into two volumes to make it easier to handle and consult. Volume 1: Background, Resources, and Tools, arranged in 5 parts, begins with chapters on the science of toxicology, its history, and informatics framework in Part 1. Part 2 continues with chapters organized by more specific subject such as cancer, clinical toxicology, genetic toxicology, etc. The categorization of chapters by resource format, for example, journals and newsletters, technical reports, organizations constitutes Part 3. Part 4 further considers toxicology's presence via the Internet, databases, and software tools. Among the miscellaneous topics in the concluding Part 5 are laws and regulations, professional education, grants and funding, and patents. Volume 2: The Global Arena offers contributed chapters focusing on the toxicology contributions of over 40 countries, followed by a glossary of toxicological terms and an appendix of popular quotations related to the field.The book, offered in both print and electronic formats, is carefully structured, indexed, and cross-referenced to enable users to easily find answers to their questions or serendipitously locate useful knowledge they were not originally aware they needed. Among the many timely topics receiving increased emphasis are disaster preparedness, nanotechnology, -omics, risk assessment, societal implications such as ethics and the precautionary principle, climate change, and children's environmental health. - Introductory chapters provide a backdrop to the science of toxicology, its history, the origin and status of toxicoinformatics, and starting points for identifying resources - Offers an extensive array of chapters organized by subject, each highlighting resources such as journals, databases,organizations, and review articles - Includes chapters with an emphasis on format such as government reports, general interest publications, blogs, and audiovisuals - Explores recent internet trends, web-based databases, and software tools in a section on the online environment - Concludes with a miscellany of special topics such as laws and regulations, chemical hazard communication resources, careers and professional education, K-12 resources, funding, poison control centers, and patents - Paired with Volume Two, which focuses on global resources, this set offers the most comprehensive compendium of print, digital, and organizational resources in the toxicological sciences with over 120 chapters contributions by experts and leaders in the field

New Developments for Nanosensors in Pharmaceutical Analysis presents an overview of developments in nanosensor usage in pharmaceutical analysis, thereby helping pharmaceutical companies attain reliable, precise, and accurate analysis of pharmaceuticals. This book presents very simple, precise, sensitive, selective, fast, and relatively inexpensive methods for pre-treatment, prior to analysis. These methods may be considered for further application in clinical studies and assays. The book includes the manufacturing of sensors for pharmaceutical analysis at nano- or smaller scales, and gives simple and relatable designs for the fabrication of sensors. Twelve chapters cover an introduction to the topic, immobilization techniques, mechanism effect of nanomaterials on structure, optical nanosensors for pharmaceutical detection, chemical nanosensors in pharmaceutical analysis, noble metal nanoparticles in electrochemical analysis of drugs, photo-electrochemical nanosensors for drug analysis, molecularly imprinted polymer based nanosensors for pharmaceutical analysis, nanomaterials for drug delivery systems, nanomaterials enriched nucleic acid-based biosensors, nanosensors in biomarker detection, and nanomaterials-based enzyme biosensors for electrochemical applications. - Presents nanosensor types, synthesis, immobilizations and applications in different fields - Gives simple repeatable designs for the fabrication of sensors for pharmaceutical analysis - Details how to carry out sensitive analysis of pharmaceuticals using nanosensors - Describes how to synthesize and immobilize nanosensors, and how nanosensors can be applied in drug assay - Proposes innovative ways to optimize pharmaceutical processes with nanosensors

DHM and Posturography explores the body of knowledge and state-of-the-art in digital human modeling, along with its application in ergonomics and posturography. The book provides an industry first introductory and practitioner focused overview of human simulation tools, with detailed chapters describing elements of posture, postural interactions, and fields of application. Thus, DHM tools and a specific scientific/practical problem – the study of posture – are linked in a coherent framework. In addition, sections show how DHM interfaces with the most common physical devices for posture analysis. Case studies provide the applied knowledge necessary for practitioners to make informed decisions. Digital Human Modelling is the science of representing humans with their physical properties, characteristics and behaviors in computerized, virtual models. These models can be used standalone, or integrated with other computerized object design systems, to design or study designs, workplaces or products in their relationship with humans. - Presents an introductory, up-to-date overview and introduction to all industrially relevant DHM systems that will enable users on trialing, procurement decisions and initial applications - Includes user-level examples and case studies of DHM application in various industrial fields - Provides a structured and posturography focused compendium that is easy to access, read and understand

Metabolons and Supramolecular Enzyme Assemblies, Volume 617 in the Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of topics, including Dynamic plant metabolons, TCA cycle metabolons, the Chemotactic assembly of metabolons, Repurposing peroxisomes for metabolic engineering, Repurposing yeast mitochondria for metabolic engineering, Repurposing plant compartments for metabolic engineering, Protein scaffolds for pathway co-localization on lipid droplets, Engineered enzyme assemblies for metabolic engineering, NRPS assembly lines and P450 interactions, and much more. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in this series on enzymology Updated release includes the latest information on dynamic plant metabolons, TCA cycle metabolons, the chemotactic assembly of metabolons, and much more

The first and second editions of Medical and Veterinary Entomology, edited by Gary R. Mullen and Lance A. Durden, published in 2002 and 2009, respectively, have been highly praised and become widely used as a textbook for classroom instruction. This fully revised third edition continues the focus on the diversity of arthropods affecting human and animal health, with separate chapters devoted to each of the taxonomic groups of insects and arachnids of medical or veterinary concern, including spiders, scorpions, mites, and ticks. Each chapter includes sections on taxonomy, morphology, life history, and behavior and ecology, with separate sections on those species of public-health and veterinary importance. Each concludes with approaches to management of pest species and prevention of arthropod-borne diseases. The third edition provides a comprehensive source for teaching medical and/or veterinary entomology at the college and university level, targeted particularly at upper-level undergraduate and graduate/postgraduate programs. In addition to its value as a student textbook, the volume has appeal to a much broader audience, specialists and non-specialists alike. It provides a key reference for biologists in general, entomologists, zoologists, parasitologists, physicians, public-health personnel, veterinarians, wildlife biologists, vector biologists, military entomologists, the general public and others seeking a readable, authoritative account on this important topic. - Completely revised and updated edition - Includes a distinguished group of 40 nationally and internationally recognized contributors - Sixteen new authors, in addition to 25 continuing contributors from the first and second editions - A new chapter on Arthropod Toxins and Venoms - Illustrated with 560, mostly color, figures and updated maps depicting the distribution of important arthropod taxa and arthropod-borne diseases - A significantly expanded and well-illustrated chapter on Molecular Tools Used in Medical and Veterinary Entomology - Coverage of emerging and newly recognized arthropod concerns, including mosquito-borne Zika and - Chikungunya viruses; tick-borne Bourbon and Heartland viruses; tick-borne rickettsioses and anaplasmosis; and red meat allergy associated with tick bites - A 1700-word Glossary - An Appendix of Arthropod-Related Viruses of Medical and Veterinary Importance

Tracking Animal Migration with Stable Isotopes, Second Edition, provides a complete introduction to new and powerful isotopic tools and applications that track animal migration, reviewing where isotope tracers fit in the modern toolbox of tracking methods. The book provides background information on a broad range of migration scenarios in terrestrial and aquatic systems and summarizes the most cutting-edge developments in the field that are revolutionizing the way migrant individuals and populations are assigned to their true origins. It allows undergraduates, graduate students and non-specialist scientists to adopt and apply isotopes to migration research, and also serves as a useful reference for scientists. The new edition thoroughly updates the information available to the reader on current applications of this technique and provides new tools for the isotopic assignment of individuals to origins, including geostatistical multi-isotope approaches and the ways in which researchers can combine isotopes with routine data in a Bayesian framework to provide best estimates of animal origins. Four new chapters include contributions on applications to the movements of terrestrial mammals, with particular emphasis on how aspects of animal physiology can influence stable isotope values. - Includes an animal physiology component that is an in-depth overview of the cautions and caveats related to this technique - Covers marine and aquatic isoscapes and methods to track marine organisms for researchers trying to apply isotopic tracking to animals in these environments - Features state-of-the-art statistical treatments for assignment and combining diverse datasets

Immunotherapy of Cancer, Volume 143, the latest release in the Advances in Cancer Research series, provides invaluable information on the exciting and fast-moving field of cancer research. Contributions from leading experts in the field make this a must have update on the topic. - Provides that latest information on cancer research - Offers outstanding and original reviews on a range of cancer research topics - Serves as an indispensable reference for researchers and students alike

World Seas: An Environmental Evaluation, Second Edition, Volume Three: Ecological Issues and Environmental Impacts covers global issues relating to our seas, including a biological description of the coast and continental shelf waters, the development and use of the coast, landfills and their effects, pollutant discharges over time, the effects of over-fishing, and the management methods and techniques used to ensure continued ecosystem functioning. The relative importance of water-borne and airborne routes differ in different parts of the world is explored, along with extensive coverage of major habitats and species groups, governmental, education and legal issues, fisheries effects, remote sensing, climate change and management. This book is an invaluable, worldwide reference source for students and researchers concerned with marine environmental science, fisheries, oceanography and engineering and coastal zone development. - Provides scientific reviews of regional issues, empowering managers and policymakers to make progress in under-resourced countries and regions - Covers environmental issues arising from the human use of both the sea and its watershed - Presents informed commentary on major trends, problems and successes, and recommendations for the future

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Advances in Imaging and Electron Physics, Volume 200, the latest release in a series that merges two long-running serials, Advances in Electronics and Electron Physics and Advances in Optical and Electron Microscopy features extended articles on the physics of electron devices (especially semiconductor devices), particle optics at high and low energies, microlithography, image science, digital image processing, electromagnetic wave propagation, electron microscopy, and computing methods. Topics in this latest release include Past and Present Attempts to Attain the Resolution Limit of the Transmission Electron Microscope, Phase Plates for Transmission Electron Microscopy, and X-Ray Lasers in Biology: Structure and Dynamics. - Contains contributions from leading authorities on the subject matter - Informs and updates on all the latest developments in the field of imaging and electron physics - Provides practitioners interested in microscopy, optics, image processing, mathematical morphology, electromagnetic fields, electron, and ion emission with a valuable resource - Features extended articles on the physics of electron devices (especially semiconductor devices), particle optics at high and low energies, microlithography, image science, and digital image processing

Rational Design of Enzyme-Nanomaterials, the new volume in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods in rational design of enzyme-nanomaterials, and includes sections on such topics as conjugation of enzymes and dextran-aldehyde polymers, improved activity of enzymes bound to titanate nanosheet, nano-layered'stable-on-the-table'biocatalysts and nanoparticle-based enzyme sensors. - Continues the legacy of this premier serial with quality chapters authored by leaders in the field - Covers research methods in rational design of enzyme-nanomaterials - Contains sections on such topics as conjugation of enzymes and dextran-aldehyde polymers, improved activity of enzymes bound to titanate nanosheet, nano-layered'stable-on-the-table'biocatalysts, and nanoparticle-based enzyme sensors

Computational Approaches for Studying Enzyme Mechanism, Part B is the first of two volumes in the Methods in Enzymology series that focuses on computational approaches for studying enzyme mechanism. The serial achieves the critically acclaimed gold standard of laboratory practices and remains one of the most highly respected publications in the molecular biosciences. Each volume is eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with over 550 volumes, the series remains a prominent and essential publication for researchers in all fields of the life sciences and biotechnology, including biochemistry, chemical biology, microbiology, synthetic biology, cancer research, genetics, and other fields of study. - Focuses on computational approaches for studying enzyme mechanism - Continues the legacy of this premier serial with quality chapters authored by leaders in the field - Covers research methods in intermediate filament associated proteins, and contains sections on such topics as lamin-associated proteins, intermediate filament-associated proteins and plakin, and other cytoskeletal cross-linkers

Advanced Inorganic Chemistry: Applications in Everyday Life connects key topics on the subject with actual experiences in nature and everyday life. Differing from other foundational texts with this emphasis on applications and examples, the text uniquely begins with a focus on the shapes (geometry) dictating intermolecular forces of attractions, leading to reactivity between molecules of different shapes. From this foundation, the text explores more advanced topics, such as: Ligands and Ligand Substitution Processes with an emphasis on Square-Planar Substitution and Octahedral Substitution Reactions in Inorganic Chemistry and Transition Metal Complexes, with a particular focus on Crystal-Field and Ligand-Field Theories, Electronic States and Spectra and Organometallic, Bioinorganic Compounds, including Carboranes and Metallacarboranes and their applications in Catalysis, Medicine and Pollution Control. Throughout the book, illustrative examples bring inorganic chemistry to life. For instance, biochemists and students will be interested in how coordination chemistry between the transition metals and the ligands has a direct correlation with cyanide or carbon monoxide poisoning (strong-field Cyanide or CO ligand versus weak-field Oxygen molecule). - Engaging discussion of key concepts with examples from the real world - Valuable coverage from the foundations of chemical bonds and stereochemistry to advanced topics, such as organometallic, bioinorganic, carboranes and environmental chemistry - Uniquely begins with a focus on the shapes (geometry) dictating intermolecular forces of attractions, leading to reactivity between molecules of different shapes

Published since 1959, Advances in Applied Microbiology continues to be one of the most widely read and authoritative review sources in microbiology. The series contains comprehensive reviews of the most current research in applied microbiology. Recent areas covered include bacterial diversity in the human gut, protozoan grazing of freshwater biofilms, metals in yeast fermentation processes and the interpretation of host-pathogen dialogue through microarrays. Eclectic volumes are supplemented by thematic volumes on various topics, including Archaea and sick building syndrome. Impact factor for 2012: 4.974. - Contributions from leading authorities - Informs and updates on all the latest developments in the field

The first review series in virology and published since 1953, Advances in Virus Research covers a diverse range of in-depth reviews, providing a valuable overview of the field. The series of eclectic volumes are valuable resources to virologists, microbiologists, immunologists, molecular biologists, pathologists, and plant researchers. Volume 89 features articles on topics including plant-based vaccines, transmission of arthropod-borne viruses by mosquitoes, arboviruses in domestic and wild animals, and more. - Contributions from leading authorities - Comprehensive reviews for general and specialist use - First and longest-running review series in virology

Hormonal Proteins and Peptides, Volume II reviews extensively the knowledge on the biology and chemistry of the protein and peptide hormones. This book presents the structures of the various protein and peptide hormones. Organized into three chapters, this volume begins with an overview of the various aspects of the structure and function of adrenocorticotropin hormone (ACTH) with reference to the ability to stimulate the adrenal gland of the rat, amphibian melanophores, and adipose tissues of the rat and rabbit. This text then reviews the isolation, purification, and elucidation of the amino acid sequence of corticotropins from various species. Other chapters consider the structures of porcine and human ACTH. This book discusses as well the working hypothesis for studies on the secondary-tertiary structure of peptide hormones. The final chapter deals with the abbreviations used for amino acids and protecting groups. This book is a valuable resource for peptide chemists, biologists, biochemists, and research workers.

Regulatory Change in an Atmosphere of Crisis: Current Implications of the Roosevelt Years is a collection of papers presented at a conference on Regulatory Change in an Atmosphere of Crisis: The Current-Day Implications of the Roosevelt Years, held in April 1978, at Washington State University. The book presents the findings on several of the major economic reforms of the Roosevelt years and assesses their implications. The text discusses a variety of issues of the period such as the short term measures implemented during the crisis of the 1930s; the Roosevelt New Deal and its consequences; banking reforms in the 1930s; and the social welfare programs that originated in the Roosevelt years. Historians, economists, financial experts, and students will find the book a great source of insight and information.

The 2e of the gold standard text in the field, Nonhuman Primates in Biomedical Research provides a comprehensive, up-to-date review of the use of nonhuman primates in biomedical research. The Diseases volume provides thorough reviews of naturally occurring diseases of nonhuman primates, with a section on biomedical models reviewing contemporary nonhuman primate models of human diseases. Each chapter contains an extensive list of bibliographic references, photographs, and graphic illustrations to provide the reader with a thorough review of the subject. - Fully revised and updated, providing researchers with the most comprehensive review of the use of nonhuman primates in bioledical research - Addresses commonly used nonhuman primate biomedical models, providing researchers with species-specific information - Includes four color images throughout

Each volume of Advances in Pharmacology provides a rich collection of reviews on timely topics. Emphasis is placed on the molecular basis of drug action, both applied and experimental. - Articles written by leading investigators in the field - Informs and updates on all the latest developments

This book presents the most current scientific understanding behind most common pain disorders. Clinical scientists involved in pain science will gain a basic understanding of the causes of many types of pain and will be able to discuss various therapies with patients. Researchers new to pain science will gain an overall understanding of pain pathophysiology and targets for pain treatments. Covering every major aspect of pain science, from molecular and cellular pathways of pain to pain disorders and their treatments, Science of Pain bridges basic and clinical research like no other book on the topic. Edited by world-renowned pain scientist and Editor-in-Chief of the journal PAIN, Allan Basbaum, this book is an in-depth reference for basic and clinical scientists in pain research who must understand the basic science of pain, and help develop new treatment strategies for pain disorders.• Presents the most current scientific understanding of neuroscience of pain, written by the world's leading experts• Integrates basic neuroscience research and clinical aspects of pain disorders• Covers both neurobiological basis and clinical treatment for a pain disorder (e.g., migraine, fibromyalgia, neuropathic pain, post-stroke pain)• Covers pain pathways and mechanisms both in text and in full-color illustrations• Includes topics specific to gender and age group addressing the trend in research toward developing individualized treatments

This latest volume in this series contains articles on the physiology of human and animal disease vectors. The papers in this special issue give rise to key themes for the future and make progress towards answering such questions as:How do insect vectors of disease find their animal hosts?Once a host is located, how do insects deploy their intricate mouthparts and the extraordinary complexities of salivary chemistry to secure a blood meal? - Contributions from the leading researchers in entomology - Discusses the physiological diversity in insects - Includes in-depth reviews with valuable information for a variety of entomology disciplines

The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with over 400 volumes (all of them still in print), the series contains much material still relevant today—truly an essential publication for researchers in all fields of life sciences. Methods in Enzymology is now available online at ScienceDirect — full-text online of volumes 1 onwards. For more information about the Elsevier Book Series on ScienceDirect Program, please visit: http://www.info.sciencedirect.com/bookseries/ This volume is the second of two planned volumes on the topic of globin and other nitric oxide-reactive proteins.

The 6th edition of a well-known and much used standard text in the field. This book covers all aspects of the biochemical abnormalities caused by various diseases and how they relate to the biochemical changes in the blood, urine, cerebrospinal fluid, joint fluids, other body fluids and in cells. The purpose is to provide the fundamental bases for understanding the biochemical changes that occur in disease processes and in turn to provide the rationale for applying this understanding to the diagnosis of the disease process. A substantial appendix is provided so that the user can quickly identify the reference ranges for a large number of animal species.• An appendix is provided in the book so that the user can quickly identify the reference ranges for a large number of animal species• Explains what biochemical changes occur in disease processes and provides the rationale for applying this understanding to the diagnosis of the disease process

Now in its third edition, Osteoporosis, is the most comprehensive, authoritative reference on this disease. Written by renowned experts in the field, this two-volume reference is a must-have for academic and medical libraries, physicians, researchers, and any company involved in osteoporosis research and development. Worldwide, 200 million women between 60-80 suffer from osteoporosis and have a lifetime risk of fracture between 30 and 40 percent continuing to make osteoporosis a hot topic in medicine. This newest edition covers everything from basic anatomy and physiology to diagnosis, management and treatment in a field where direct care costs for osteoporitic fractures in the U.S. reach up to $18 billion each year.NEW TO THIS EDITION:•Recognizes the critical importance of the Wnt signaling pathway for bone health •Incorporates new chapters on osteocytes, phosphatonins, mouse genetics, and CNS and bone •Examines essential updates on estrogen prevention and treatment and the recent results from the WHI •Discusses the controversial topics of screening and clinical trial design for drug registration •Includes essential updates on therapeutic uses of calcium, vitamin D, SERMS, bisphosphonates, and parathyroid hormone • Offers critical reviews of reproductive and hormonal risk factors, ethnicity, nutrition, therapeutics, management, and economics comprising a tremendous wealth of knowledge in a single source not found elsewhere

First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. In the early days of the serial, the subjects of vitamins and hormones were quite distinct. The Editorial Board now reflects expertise in the field of hormone action, vitamin action, X-ray crystal structure, physiology, and enzyme mechanisms. Under the capable and qualified editorial leadership of Dr. Gerald Litwack, Vitamins and Hormones continues to publish cutting-edge reviews of interest to endocrinologists, biochemists, nutritionists, pharmacologists, cell biologists, and molecular biologists. Others interested in the structure and function of biologically active molecules like hormones and vitamins will, as always, turn to this series for comprehensive reviews by leading contributors to this and related disciplines.

Biology of Disease Vectors presents a comprehensive and advanced discussion of disease vectors and what the future may hold for their control. This edition examines the control of disease vectors through topics such as general biological requirements of vectors, epidemiology, physiology and molecular biology, genetics, principles of control and insecticide resistance. Methods of maintaining vectors in the laboratory are also described in detail.No other single volume includes both basic information on vectors, as well as chapters on cutting-edge topics, authored by the leading experts in the field. The first edition of Biology of Disease Vectors was a landmark text, and this edition promises to have even more impact as a reference for current thought and techniques in vector biology.Current - each chapter represents the present state of knowledge in the subject areaAuthoritative - authors include leading researchers in the fieldComplete - provides both independent investigator and the student with a single reference volume which adopts an explicitly evolutionary viewpoint throuoghout all chapters. Useful - conceptual frameworks for all subject areas include crucial information needed for application to difficult problems of controlling vector-borne diseases

Advances in Agronomy continues to be recognized as a leading reference and a first-rate source of the latest research in agronomy. Major reviews deal with the current topics of interest to agronomists, as well as crop and soil scientists. As always, the subjects covered are varied and exemplary of the myriad subject matter dealt with by this long-running serial. Editor Donald Sparks, former president of the Soil Science Society of America and current president of the International Union of Soil Science, is the S. Hallock du Pont Chair of Plant and Soil Sciences at The University of Delaware. Volume 83 contains five excellent reviews that discuss topics critical to agricultural and environmental sustainability. - Maintains the highest impact factor among serial publications in Agriculture - Presents timely reviews on important agronomy issues - Enjoys a long-standing reputation for excellence in the field

The topic of antigenic variation is important in both biology and medicine. It is of enormous interest, as it describes the process(es) whereby microorganisms'shift shape', by genetic rearrangement or otherwise. In medical terms, this has a major impact on the infectious disease process, since the immune system has great difficulty in keeping up with this variation, and thus eliminating the infectious agent. Antigenic variation is a major method by which microbes evade the immune response, and persist in the body.The broad scope of the book appeals to all those working in the field of infectious disease, immunology of infection, pathogenesis, molecular biology and also to evolutionary biologists. Topics covered include not only bacterial species, and viruses such as influenza, HIV, Rotavirus, but also eukaryotic parasites - one of the most fascinating groups of organisms exhibiting this behaviour.Comprehensive coverage of antigenic variation from viruses to parasitesDiscussions devoted to molecular mechanisms of host evasionDetailed descriptions of host/pathogen interactions

Medical and Veterinary Entomology is a comprehensive text and is primarily intended for graduate students and upper level undergraduates studying the medical and veterinary significance of insects and related arthropods. The book will also appeal to a larger audience, specialists and non-specialists alike, including entomologists, parasitologists, biologists, epidemiologists, physicians, public health personnel, veterinarians, wildlife specialists and others looking for a readable, authoritative book on this topic. The first two chapters provide overviews of medical-veterinary entomology and epidemiology, respectively. These are followed by individual chapters devoted to each group of insects or arachnids of medical-veterinary importance and the health problems they can cause including their role as vectors of pathogens. Each of these chapters provides an overview of the taxonomy, biology and ecology of the group, and is followed by separate sections on their medical and veterinary importance, then by a section on prevention and control and, finally, by a list of references and further reading. - Nationally and internationally renowned contributing authors - Up to date and new information that is easy to locate, with extensive subheadings and highlighted key words throughout text - Includes extensive coverage of arachnids, including scorpions, solpugids, spiders, mites and ticks - Designed for teaching several courses including Medical Entomology, Veterinary Entomology or combined Medical-Veterinary Entomology courses

This volume contains a comprehensive overview of peptide-lipid interactions by leading researchers. The first part covers theoretical concepts, experimental considerations, and thermodynamics. The second part presents new results obtained through site-directed EPR, electron microscopy, NMR, isothermal calorimetry, and fluorescence quenching. The final part covers problems of biological interest, including signal transduction, membrane transport, fusion, and adhesion.Key Features• world-renowned experts• state-of-the-art experimental methods• monolayers, bilayers, biological membranes • theoretical aspects and computer simulations• rafts• synaptic transmission• membrane fusion• signal transduction

International Review of Cytology presents current advances and comprehensive reviews in cell biology—both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research. - Authored by some of the foremost scientists in the field - Provides up-to-date information and directions for future research - Valuable reference material for advanced undergraduates, graduate students and professional scientists

This volume contains a comprehensive overview of peptide-lipid interactions by leading researchers. The first part covers theoretical concepts, experimental considerations, and thermodynamics. The second part presents new results obtained through site-directed EPR, electron microscopy, NMR, isothermal calorimetry, and fluorescence quenching. The final part covers problems of biological interest, including signal transduction, membrane transport, fusion, and adhesion.Key Features• world-renowned experts• state-of-the-art experimental methods• monolayers, bilayers, biological membranes • theoretical aspects and computer simulations• rafts• synaptic transmission• membrane fusion• signal transduction

Here is the most comprehensive and up-to-date treatment of one of the hottest areas of chemical research. The treatment of fundamental kinetics and photochemistry will be highly useful to chemistry students and their instructors at the graduate level, as well as postdoctoral fellows entering this new, exciting, and well-funded field with a Ph.D. in a related discipline (e.g., analytical, organic, or physical chemistry, chemical physics, etc.). Chemistry of the Upper and Lower Atmosphere provides postgraduate researchers and teachers with a uniquely detailed, comprehensive, and authoritative resource. The text bridges the'gap'between the fundamental chemistry of the earth's atmosphere and'real world'examples of its application to the development of sound scientific risk assessments and associated risk management control strategies for both tropospheric and stratospheric pollutants. - Serves as a graduate textbook and'must have'reference for all atmospheric scientists - Provides more than 5000 references to the literature through the end of 1998 - Presents tables of new actinic flux data for the troposphere and stratospher (0-40km) - Summarizes kinetic and photochemical date for the troposphere and stratosphere - Features problems at the end of most chapters to enhance the book's use in teaching - Includes applications of the OZIPR box model with comprehensive chemistry for student use

For many years the use of chemical agents such as pesticides and herbicides has been effective in controlling the many varieties of pests that infest both agricultural crops and backyard gardens. However, these pests are gradually becoming resistant to these agents, because the agents themselves are acting as selective factors making the pests better and better able to resist and persist. As a result, the use of biological controlling agents is increasing. This book is a comprehensive and authoritative handbook of biological control.

Recombinant DNA methods are powerful, revolutionary techniques that allow the isolation of single genes in large amounts from a pool of thousands or millions of genes and the modification of these isolated genes or their regulatory regions for reintroduction into cells for expression at the RNA or protein levels. These attributes lead to the solution of complex biological problems and the production of new and better products in the areas of medicine, agriculture, and industry. Recombinant DNA Methodology, a volume in the Selected Methods in Enzymology series produced in benchtop format, contains a selection of key articles from Volumes 68, 100, 101, 153, 154, and 155 of Methods in Enzymology. The essential and widely used procedures provided at an affordable price will be an invaluable aid to the graduate student and the researcher. - Enzymes in DNA research - DNA isolation, hybridization, and cloning - DNA sequence analysis - cDNA cloning - Gene products - Identification of cloned genes and mapping of genes - Monitoring cloned gene expression - Cloning and transferring of genes into yeast cells - Cloning and transferring of genes into plant cells - Cloning and transferring of genes into animal cells - Site-directed mutagenesis - Protein engineering - Expression vectors

Crop Safeners for Herbicides aims to discuss the issue of chemical manipulation of crop tolerance to herbicides. This book resulted from a symposium titled''Chemical Manipulation of Crop Tolerance to Herbicides''. Several chapters included herein are added contributions from experts outside of the symposium. The book not only serves as reference for the knowledge of the agronomic uses, development, chemistry, and mechanisms of action herbicide safeners, but it also assesses the impact of safeners all around the world. It also presents a discussion on alternative approaches that increases herbicide selectivity and explores future trends. Comprised of 16 chapters and divided into four parts, the book starts with a section on the development and uses of herbicide safeners. The text also offers a critical and extensive review of academic and industrial perspectives in the development of herbicide safeners in different parts of the world. Part 2 of this book starts with an overview of the physiological, biochemical, and molecular aspects of the mechanisms, and then further delves in to the prevalent mechanisms of action of selected classes of herbicide safeners. The third part of this book provides data on the potential use of alternative approaches for the manipulation of crop tolerance to herbicides. The last part is a summary of the progress and prospects of the topic of crop safening against herbicide injury. The book serves as an important resource for students and professionals interested in the field of agriculture, agronomy, pest research, weed science, and plant pathology and physiology.

The Plasma Proteins: Structure, Function, and Genetic Control, Second Edition, Volume V explores the contribution of molecular biology and gene cloning approaches to the advancement of plasma protein structure, function, and genomic organization studies. This volume is composed of five chapters and begins with a discussion on the DNA sequences and chromosomal location of plasma protein genes, specifically the cloning and sequencing of immunoglobulin genes. These topics are followed by a discussion on the advances in relation to discovered genetic variants present either as normal phenotypes or in dyslipoproteinemic states associated with cardiovascular disease. A chapter highlights the application of molecular biology techniques to the study of gene structure and the translational and maturation steps of every major plasma apolipoprotein. Another chapter emphasizes the unique features of protein structure and the conformational changes that characterize the assembly of macromolecular complexes in plasma and on cell surfaces. The concluding chapter provides a comprehensive review of the integration of molecular biology, physiology, and pathology of plasma proteins and their response in inflammation. This book will be of great value to molecular biologists, physiologists, pathologists, and clinicians.

Methods in Immunology and Immunochemistry, Volume IV: Agglutination, Complement, Neutralization, and Inhibition provides information pertinent to direct and indirect agglutination reactions. This book covers a variety of topics, including complement-fixation procedures, isolation of complement components, hemolytic intermediates, complement-related proteins, and neutralization reactions. Organized into three chapters, this volume begins with an overview of test-tube agglutinations that are preferred for blood grouping with saline agglutinins that require more than a few minutes for agglutination. This text then describes blood group antibodies that agglutinate red blood cells suspended in saline. Other chapters consider the classical pathway of complement utilization. This book discusses as well the complexity of events leading to hemolysis of erythrocytes by complement. The final chapter deals with the ability of antitoxin to neutralize diphtheria toxin and explains the quantitative relationships between antigen and antibody. This book is a valuable resource for immunologists, scientists, and research workers.

The Hormones: Physiology, Chemistry and Applications, Volume III covers the chemistry, physiology, and methods of analysis of various plant and animal hormones. This book is organized into 15 chapters that are mostly revision or reassessment of previous information presented in Volumes I and II. The first two chapters describe the chromatographic separation of plants hormones, particularly auxins, as well as hormones in invertebrates. These topics are followed by a chapter on the production, transport, storage, release, and mode of action of neurohormones. Significant chapters are devoted to the chemistry and physiology of secreted hormones, including parathyroid, pituitary, Islets of Langerhans, growth, lactogenic, thyroid, steroid, and sex hormones. The role and influence of these hormones on vital body processes are also discussed. The last chapter emphasizes the progress in understanding the principles and approaches in clinical endocrinology. This volume will be of great value to endocrinologists, physiologists, and biochemists.

Vitamins and Hormones

Annual Reports in Medicinal Chemistry

Annual Reports in Medicinal Chemistry

Annual Reports in Medicinal Chemistry

Annual Reports in Medicinal Chemistry

'Its continuity of pertineence, excellence, and authority remains unbroken - a tribute to the skillful editing and writing involved. Every informed laboratory staff must have available a copy of this volume.'- CLINICAL CHEMISTRYFor more than thirty years, this serial has helped to broaden the technical scope and expand the scientific base of clinical chemistry. These volumes will clarify the areas of molecular biology, informatics, and the monitoring of physiological parameters in crticial situations as they pertain to clinical chemistry. Each volume of Advances in Clinical Chemistry contains an index, and each chapter includes references.