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The article is concerned with the issue of a standardized approach to determining the effectiveness of allergen-specific therapy (AST) in children. AST has a special role in treating allergy: only this method can induce clinical and immunological tolerance to the cause-significant allergen; is safe enough and highly effective; reduces the duration of acute conditions; reduces the necessity for both basic therapy medicines and additional symptomatic therapy; is capable of preventing the progression of allergic diseases by reducing the sensibility spectre and the formation of bronchial asthma in those suffering from allegic rhinitis; improves the control over the disease and has a positive effect on the patient’s and his family quality of life. At the moment evaluating the effectiveness of medical technologies is one of the most important tasks in medicine while the effectiveness and safety of any medical intervention should be obtained in accordance with the requirements of evidence-based medicine. In order to determine the effectiveness of AST in children, a combined clinical and pharmaceutical evaluation should be performed and as a secons point — determine the patient’s life quality and also evaluate the gravity of symptoms according to the visual analogue scale, and to count the number of days with the symptoms and without them.

Background : The basis of the treatment of patients with cystic fibrosis (CF) is kinesitherapy — a special respiratory gymnastics and drainage of a bronchial tree. The increase of efficiency of a complex of medical rehabilitation measures can be reached by the application of a method of the high-frequency chest wall oscillation (HFCWO). Aim: To develop additional criteria of the individual program of classes by HFCWO system for children with CF. Patients and methods : The research involved 43 children with CF at the age of 2 years 10 months — 17.5 years whose treatment included 14 HFCWO procedures. During the first 4 classes 10 children from them received the oscillations calculated according to the age, and from the 5th class — according to the severity of CF course and indicators of a volume of the forced expiration for the first second (VFE1) — subgroup I. The patients, included in the subgroup II (n = 33), from the first occupation received the oscillations calculated on the severity of CF course and according to VFE1 indicators. Results: In the subgroup I during the first 4 classes there were no improvements of the peakflowmetry indicators (р >0.05), all children had complaints to discomfort from the procedure. From the 5th class clinical functional dynamics started being noted, to the 8th class indicators amounted to the subgroup II in which positive changes were registered from the first class. To the 14th occupation the VFE1 indicators improved in I and II subgroups: with a high CF severity (from 42.5 ± 5.5 to 58.1 ± 1.6%; р = 0.015) and with a course of medium severity (from 71.1 ± 1.2 to 80.0 ± 2.8%; р = 0.025). In addition all patients showed the improvement of the peakflowmetry indicators and excursion of a chest wall (cm; р

Cough is the main symptom of respiratory tract lesion. It is commonly caused by viral, mixed (viral-bacterial) and bacterial respiratory infections. Upon that it may be both a sign of respiratory system pathology and a reflex response to other organs and systems disorders. In spite of expert’s close attention to the cough problem it is still urgent as ever. The studies of its causes are currently in progress, diagnostic patterns and treatment methods are improved. In the article potential causes of cough in children due to their age are analyzed, principal lines for diagnostic search and approaches to therapy of cough syndrome in children are presented. Special attention is paid to medication of cough symptomatic treatment. It is shown that selection of drugs depends on cough characteristics, its strength and other features.