Search

Your search keyword '"Zimmermann, Alexander"' showing total 26 results
Start Over Author "Zimmermann, Alexander" Publication Year Range This year
26 results on '"Zimmermann, Alexander"'

1. Differential graded division algebras, their modules, and dg-simple algebras

Author

Zimmermann, Alexander

Subjects
Mathematics - Rings and Algebras, Mathematics - Representation Theory, 16E45
Abstract

We give the definition of a dg-division algebra, that is a concept of a differential graded algebra which may serve as an analogue of a division algebra. We classify them completely, and show that they are either acyclic or have differential $0$. Further, we prove that the graded centre of dg-simple dg-algebras is a dg-division algebra, and also the dg-endomorphism ring of a dg-simple module is a dg-division algebra. We also shall give a Jacobson-Chevalley density theorem for acyclic dg-algebras., Comment: Substantial revision

Published
2024

5. The sac evolution imaging follow-up after endovascular aortic repair: An international expert opinion-based Delphi consensus study

Author

Beck, Adam W., Hertault, Adrien, Savlania, Ajay, Froio, Alberto, Giaquinta, Alessia, Zimmermann, Alexander, Psyllas, Anastasios, Wanhainen, Anders, Marchetti, Andrea Ascoli, Queiroz, Andre Brito, Kahlberg, Andrea, Reyes-Valdivia, Andrés, Schanzer, Andres, Tambyraja, Andrew, Freyrie, Antonio, Lorido, Antonio, Millon, Antoine, Ippoliti, Arnaldo, Abai, Babak, Mees, Barend, Reutersberg, Benedikt, Maurel, Blandine, Michel, Bosiers, Wahlgren, Carl Magnus, Cavazzini, Carlo, Setacci, Carlo, Lee, Cheong Jun, Ferrer, Ciro, Bicknell, Colin, Raphaël, Coscas, Clair, Daniel, Dawson, David L., Arnaoutakis, Dean J., Böckler, Dittmar, Kotelis, Drosos, Mujagic, Edin, Chisci, Emiliano, Cieri, Enrico, Gallitto, Enrico, Marone, Enrico Maria, Ducasse, Eric, Verzini, Fabio, Pecoraro, Felice, Serracino-Inglott, Ferdinand, Benedetto, Filippo, Speziale, Francesco, Stilo, Francesco, Álvarez-Marcos, Francisco, Pagliariccio, Gabriele, Piffaretti, Gabriele, Lanza, Gaetano, Philipp, Geisbüsch, Geenberg, George, Jung, Georg, Melissano, Germano, Veraldi, Gian Franco, Parlani, Gianbattista, Faggioli, Gianluca, de Donato, Gianmarco, Simonte, Gioele, Colacchio, Giovanni, De Caridi, Giovanni, Pratesi, Giovanni, Spinella, Giovanni, Torsello, Giovanni, Leong Tan, Glenn Wei, Magee, Gregory A., Verhagen, Hence, Andrew, Holden, Koleilat, Issam, Ohman, J. Westley, de Vries, J.P.P.M., Budtz-Lilly, Jacob, Black, James, Eldrup-Jorgensen, Jens, Hockley, Joe, Bath, Jonathan, Sobocinski, Jonathan, van Herwaarden, Joost A., Reinhard, Kopp, Orion, Kristine C., Amankwah, Kwame, Bertoglio, Luca, di Marzo, Luca, Garriboli, Luca, Rizzo, Luigi, Hakimi, Maani, Sheahan, Malachi, Khashram, Manar, Schermerhorn, Marc, Lescan, Mario, Conrad, Mark, Davies, Mark G., Czerny, Martin, Orrico, Matteo, Eagleton, Matthew J., Smeds, Matthew R., Taurino, Maurizio, Wohlauer, Max, Sharafuddin, Mel J., Anna-Leonie, Menges, Reijnen, Michel, Antonello, Michele, Piazza, Michele, Settembre, Nicla, Mouawad, Nicolas J., Tsilimparis, Nikolaos, Dias, Nuno, Martinelli, Ombretta, Frigatti, Paolo, Sirignano, Pasqualino, Chong, Patrick, Bevis, Paul, DiMuzio, Paul, Henke, Peter, Düppers, Philip, Holt, Peter, Helmiö, Päivi, Vriens, Patrick, Pulli, Raffaele, Bellosta, Raffaello, Micheli, Raimondo, Veeraswamy, Ravi, Cuff, Robert, Chiappa, Roberto, Gattuso, Roberto, Pini, Rodolfo, Dalman, Ronald L., Milner, Ross, Scali, Salvatore T., Bahia, Sandeep, Laukontaus, Sani, Trimarchi, Santi, Fernandez-Alonso, Sebastian, Deglise, Sebastien, Bellmunt-Montoya, Sergi, Hofer, Simone, Yusuf, Syed W., Ronchey, Sonia, Bartoli, Stefano, Bonvini, Stefano, Camparini, Stefano, Fazzini, Stefano, Pirrelli, Stefano, Hörer, Tal, Bisdas, Theodosios, Vasudevan, Thodur, Lattmann, Thomas, Wyss, Thomas Rudolf, Maldonado, Thomas, Pfammatter, Thomas, Kölbel, Tilo, Jakimowicz, Tomasz, Donati, Tommaso, Tracci, Margaret, Bracale, Umberto Marcello, Tolva, Valerio Stefano, Riambau, Vincent, Palazzo, Vincenzo, Makaloski, Vladimir, Von Allmen, Regula S., Dorigo, Walter, Mansour, Wassim, Van den Eynde, Wouter, Tinelli, Giovanni, D’Oria, Mario, Sica, Simona, Mani, Kevin, Rancic, Zoran, Resch, Timothy Andrew, Beccia, Flavia, Azizzadeh, Ali, Da Volta Ferreira, Marcelo Martins, Gargiulo, Mauro, Lepidi, Sandro, Tshomba, Yamume, Oderich, Gustavo S., and Haulon, Stéphan

Published
2024
Full Text
View/download PDF

9. Preventive Aortic Stent Graft Implantation Prior to Thoracic Surgery: Early and Midterm Results.

Author

Lauk, Olivia, Battilana, Bianca, Schneiter, Didier, Schmitt-Opitz, Isabelle, Zimmermann, Alexander, and Reutersberg, Benedikt

Subjects
THORACIC aorta, ENDOVASCULAR surgery, LITERATURE reviews, THORACIC surgery, LUNG surgery
Abstract

Background: There is a paucity of data concerning the feasibility and value of thoracic aortic stent graft implantation (TEVAR) applications for removing tumors infiltrating the aortic wall. This analysis aimed to demonstrate the feasibility of TEVAR and monitor the perioperative risks of morbidity and mortality. Additionally, a literature review was performed. Methods: A retrospective data analysis was performed on patients who received TEVAR prior to thoracic malignancy resection between January 2010 and April 2024. The primary endpoint was technical success. Results: A total of 15 patients (median age: 67 years; range: 23–75; 66.7% female) received TEVAR prior to thoracic surgery of different tumor entities. In 80% of cases (n = 12), the proximal landing zone was in aortic zone 3. In three cases, the supra-aortic debranching of LSA and/or LCCA via bypass implantation or in situ laser fenestration was necessary. No postoperative endograft-related complications were observed. In eight patients, aortic wall infiltration was confirmed intraoperatively. In total, R0 resection was achieved in seven patients (46.7%). The 30-day mortality rate was 6.7% (n = 1). Technical success was achieved in all patients (100%), while procedural success was achieved in 80% due to incomplete tumor resection in three patients. Conclusions: To the best of our knowledge, this is the largest analysis to date that confirms the results of previous smaller studies. Aortic stent grafting prior to thoracic tumor resection allows for extensive resection while maintaining low morbidity and a low 30-day mortality risk. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

10. Influence of Bridging Stent Graft Implantation into the Renal Artery during Complex Endovascular Aortic Procedures on the Renal Resistance Index.

Author

Reitnauer, Daniela, Stoklasa, Kerstin, Dueppers, Philip, Reutersberg, Benedikt, Zimmermann, Alexander, and Stadlbauer, Thomas H. W.

Subjects
ENDOVASCULAR aneurysm repair, ENDOVASCULAR surgery, RENAL artery, VASCULAR resistance, ABDOMINAL aortic aneurysms
Abstract

Comparative sonographic examination of the renal resistance index (RRI) can provide evidence of renal artery stenosis. The extent to which the RRI is changed after stent graft implantation is not known. The aim of this study was to investigate the influence of stent graft implantation into non-diseased renal arteries during endovascular treatment of pararenal aortic aneurysms on the RRI. Sonographic examinations of the kidneys were conducted using a GE ultrasound system. The evaluation was performed according to the European Society for Vascular Surgery (ESVS) 2D standard criteria. RRI values were determined in consecutive patients on the day before and after stent graft implantation and compared for each kidney. A total of 32 consecutive patients (73.9 ± 8.2 years, 5 females, 27 males) were treated with a fenestrated or branched aortic stent graft including bridging stent graft implantations into both renal arteries and received pre- and postinterventional examinations. Sonomorphologically, the examined kidneys were inconspicuous. The arborisation of the renal perfusion was preserved pre- and post-implantation. The RRI did not differ (0.66 ± 0.06 versus 0.67 ± 0.07; p = ns). Successful stent graft implantation into non-stenosed renal arteries did not lead to a relevant change in RRI. Therefore, the RRI is a suitable tool for assessing renal perfusion after fenestrated or branched endovascular aortic therapy. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

11. Bypass Patency and Amputation-Free Survival after Popliteal Aneurysm Exclusion Significantly Depends on Patient Age and Medical Complications: A Detailed Dual-Center Analysis of 395 Consecutive Elective and Emergency Procedures

Author

Freytag, Hannah, primary, Kapalla, Marvin, additional, Berg, Floris, additional, Stroth, Hans-Christian Arne, additional, Reisenauer, Tessa, additional, Stoklasa, Kerstin, additional, Zimmermann, Alexander, additional, Reeps, Christian, additional, Knappich, Christoph, additional, Wolk, Steffen, additional, and Busch, Albert, additional

Published
2024
Full Text
View/download PDF

14. The Sac Evolution Imaging Follow-Up after EVAR: an international expert opinion-based Delphi consensus study

Author

Tinelli, G, D’Oria, M, Sica, S, Mani, K, Rancic, Z, Resh, T, Beccia, F, Azizzadeh, A, Da Volta Ferreira, M, Gargiulo, M, Lepidi, S, Tshomba, Y, Oderich, G, Haulon, S, Beck, A, Hertault, A, Savlania, A, Froio, A, Giaquinta, A, Zimmermann, A, Psyllas, A, Wanhainen, A, Marchetti, A, Queiroz, A, Kahlberg, A, Reyes-Valdivia, A, Schanzer, A, Edinburgh Vascular, A, Freyrie, A, Lorido, A, Millon, A, Ippoliti, A, Abai, B, Mees, B, Reutersberg, B, Maurel, B, Michel, B, Wahlgren, C, Cavazzini, C, Setacci, C, Lee, C, Ferrer, C, Bicknell, C, Raphaël, C, Clair, D, Dawson, D, Arnaoutakis, D, Böckler, D, Kotelis, D, Mujagic, E, Chisci, E, Cieri, E, Gallitto, E, Marone, E, Ducasse, E, Verzini, F, Pecoraro, F, Serracino-Inglott, F, Benedetto, F, Speziale, F, Stilo, F, Álvarez-Marcos, F, Pagliariccio, G, Piffaretti, G, Lanza, G, Philipp, G, Geenberg, G, Jung, G, Melissano, G, Veraldi, G, Parlani, G, Faggioli, G, de Donato, G, Simonte, G, Colacchio, G, De Caridi, G, Pratesi, G, Spinella, G, Torsello, G, Leong Tan, G, Magee, G, Verhagen, H, Andrew, H, Koleilat, I, Ohman, J, de Vries, J, Budtz-Lilly, J, Black, J, Eldrup-Jorgensen, J, Hockley, J, Bath, J, Sobocinski, J, van Herwaarden, J, Reinhard, K, Orion, K, Amankwah, K, Bertoglio, L, di Marzo, L, Garriboli, L, Rizzo, L, Hakimi, M, Sheahan, M, Khashram, M, Schermerhorn, M, Lescan, M, Conrad, M, Davies, M, Czerny, M, Orrico, M, Eagleton, M, Smeds, M, Taurino, M, Wohlauer, M, Sharafuddin, M, Anna-Leonie, M, Reijnen, M, Antonello, M, Piazza, M, Settembre, N, Mouawad, N, Tsilimparis, N, Dias, N, Martinelli, O, Frigatti, P, Sirignano, P, Chong, P, Bevis, P, Dimuzio, P, Henke, P, Düppers, P, Holt, P, Helmiö, P, Vriens, P, Pulli, R, Bellosta, R, Micheli, R, Veeraswamy, R, Cuff, R, Chiappa, R, Gattuso, R, Pini, R, Dalman, R, Milner, R, Scali, S, Bahia, S, Laukontaus, S, Trimarchi, S, Fernandez-Alonso, S, Deglise, S, Bellmunt-Montoya, S, Hofer, S, Yusuf, S, Ronchey, S, Bartoli, S, Bonvini, S, Camparini, S, Fazzini, S, Pirrelli, S, Hörer, T, Bisdas, T, Vasudevan, T, Lattmann, T, Wyss, T, Maldonado, T, Pfammatter, T, Kölbel, T, Jakimowicz, T, Donati, T, Tracci, M, Bracale, U, Tolva, V, Riambau, V, Palazzo, V, Makaloski, V, Regula S, V, Dorigo, W, Mansour, W, Van den Eynde, W, Tinelli, Giovanni, D’Oria, Mario, Sica, Simona, Mani, Kevin, Rancic, Zoran, Resh, Timothy Andrew, Beccia, Flavia, Azizzadeh, Ali, Da Volta Ferreira, Marcelo Martins, Gargiulo, Mauro, Lepidi, Sandro, Tshomba, Yamume, Oderich, Gustavo S., Haulon, Stephan, Beck, Adam W., Hertault, Adrien, Savlania, Ajay, Froio, Alberto, Giaquinta, Alessia, Zimmermann, Alexander, Psyllas, Anastasios, Wanhainen, Anders, Marchetti, Andrea Ascoli, Queiroz, Andre Brito, Kahlberg, Andrea, Reyes-Valdivia, Andrés, Schanzer, Andres, Edinburgh Vascular, Andrew Tambyraja, Freyrie, Antonio, Lorido, Antonio, Millon, Antoine, Ippoliti, Arnaldo, Abai, Babak, Mees, Barend, Reutersberg, Benedikt, Maurel, Blandine, Michel, Bosiers, Wahlgren, Carl Magnus, Cavazzini, Carlo, Setacci, Carlo, Lee, Cheong Jun, Ferrer, Ciro, Bicknell, Colin, Raphaël, Coscas, Clair, Daniel, Dawson, David L., Arnaoutakis, Dean J., Böckler, Dittmar, Kotelis, Drosos, Mujagic, Edin, Chisci, Emiliano, Cieri, Enrico, Gallitto, Enrico, Marone, Enrico Maria, Ducasse, Eric, Verzini, Fabio, Pecoraro, Felice, Serracino-Inglott, Ferdinand, Benedetto, Filippo, Speziale, Francesco, Stilo, Francesco, Álvarez-Marcos, Francisco, Pagliariccio, Gabriele, Piffaretti, Gabriele, Lanza, Gaetano, Philipp, Geisbüsch, Geenberg, George, Jung, Georg, Melissano, Germano, Veraldi, Gian Franco, Parlani, Gianbattista, Faggioli, Gianluca, de Donato, Gianmarco, Simonte, Gioele, Colacchio, Giovanni, De Caridi, Giovanni, Pratesi, Giovanni, Spinella, Giovanni, Torsello, Giovanni, Leong Tan, Glenn Wei, Magee, Gregory A., Verhagen, Hence, Andrew, Holden, Koleilat, Issam, Ohman, J Westley, de Vries, J. P. P. M., Budtz-Lilly, Jacob, Black, James, Eldrup-Jorgensen, Jens, Hockley, Joe, Bath, Jonathan, Sobocinski, Jonathan, van Herwaarden, Joost A., Reinhard, Kopp, Orion, Kristine C., Amankwah, Kwame, Bertoglio, Luca, di Marzo, Luca, Garriboli, Luca, Rizzo, Luigi, Hakimi, Maani, Sheahan, Malachi, Khashram, Manar, Schermerhorn, Marc, Lescan, Mario, Conrad, Mark, Davies, Mark G., Czerny, Martin, Orrico, Matteo, Eagleton, Matthew J., Smeds, Matthew R., Taurino, Maurizio, Wohlauer, Max, Sharafuddin, Mel J., Anna-Leonie, Menges, Reijnen, Michel, Antonello, Michele, Piazza, Michele, Settembre, Nicla, Mouawad, Nicolas J., Tsilimparis, Nikolaos, Dias, Nuno, Martinelli, Ombretta, Frigatti, Paolo, Sirignano, Pasqualino, Chong, Patrick, Bevis, Paul, DiMuzio, Paul, Henke, Peter, Düppers, Philip, Holt, Peter, Helmiö, Päivi, Vriens, Patrick, Pulli, Raffaele, Bellosta, Raffaello, Micheli, Raimondo, Veeraswamy, Ravi, Cuff, Robert, Chiappa, Roberto, Gattuso, Roberto, Pini, Rodolfo, Dalman, Ronald L., Milner, Ross, Scali, Salvatore T., Bahia, Sandeep, Laukontaus, Sani, Trimarchi, Santi, Fernandez-Alonso, Sebastian, Deglise, Sebastien, Bellmunt-Montoya, Sergi, Hofer, Simone, Yusuf, Syed W., Ronchey, Sonia, Bartoli, Stefano, Bonvini, Stefano, Camparini, Stefano, Fazzini, Stefano, Pirrelli, Stefano, Hörer, Tal, Bisdas, Theodosios, Vasudevan, Thodur, Lattmann, Thomas, Wyss, Thomas Rudolf, Maldonado, Thomas, Pfammatter, Thomas, Kölbel, Tilo, Jakimowicz, Tomasz, Donati, Tommaso, Tracci, Margaret, Bracale, Umberto Marcello, Tolva, Valerio Stefano, Riambau, Vincent, Palazzo, Vincenzo, Makaloski, Vladimir, Regula S, Von Allmen, Dorigo, Walter, Mansour, Wassim, Van den Eynde, Wouter, Tinelli, G, D’Oria, M, Sica, S, Mani, K, Rancic, Z, Resh, T, Beccia, F, Azizzadeh, A, Da Volta Ferreira, M, Gargiulo, M, Lepidi, S, Tshomba, Y, Oderich, G, Haulon, S, Beck, A, Hertault, A, Savlania, A, Froio, A, Giaquinta, A, Zimmermann, A, Psyllas, A, Wanhainen, A, Marchetti, A, Queiroz, A, Kahlberg, A, Reyes-Valdivia, A, Schanzer, A, Edinburgh Vascular, A, Freyrie, A, Lorido, A, Millon, A, Ippoliti, A, Abai, B, Mees, B, Reutersberg, B, Maurel, B, Michel, B, Wahlgren, C, Cavazzini, C, Setacci, C, Lee, C, Ferrer, C, Bicknell, C, Raphaël, C, Clair, D, Dawson, D, Arnaoutakis, D, Böckler, D, Kotelis, D, Mujagic, E, Chisci, E, Cieri, E, Gallitto, E, Marone, E, Ducasse, E, Verzini, F, Pecoraro, F, Serracino-Inglott, F, Benedetto, F, Speziale, F, Stilo, F, Álvarez-Marcos, F, Pagliariccio, G, Piffaretti, G, Lanza, G, Philipp, G, Geenberg, G, Jung, G, Melissano, G, Veraldi, G, Parlani, G, Faggioli, G, de Donato, G, Simonte, G, Colacchio, G, De Caridi, G, Pratesi, G, Spinella, G, Torsello, G, Leong Tan, G, Magee, G, Verhagen, H, Andrew, H, Koleilat, I, Ohman, J, de Vries, J, Budtz-Lilly, J, Black, J, Eldrup-Jorgensen, J, Hockley, J, Bath, J, Sobocinski, J, van Herwaarden, J, Reinhard, K, Orion, K, Amankwah, K, Bertoglio, L, di Marzo, L, Garriboli, L, Rizzo, L, Hakimi, M, Sheahan, M, Khashram, M, Schermerhorn, M, Lescan, M, Conrad, M, Davies, M, Czerny, M, Orrico, M, Eagleton, M, Smeds, M, Taurino, M, Wohlauer, M, Sharafuddin, M, Anna-Leonie, M, Reijnen, M, Antonello, M, Piazza, M, Settembre, N, Mouawad, N, Tsilimparis, N, Dias, N, Martinelli, O, Frigatti, P, Sirignano, P, Chong, P, Bevis, P, Dimuzio, P, Henke, P, Düppers, P, Holt, P, Helmiö, P, Vriens, P, Pulli, R, Bellosta, R, Micheli, R, Veeraswamy, R, Cuff, R, Chiappa, R, Gattuso, R, Pini, R, Dalman, R, Milner, R, Scali, S, Bahia, S, Laukontaus, S, Trimarchi, S, Fernandez-Alonso, S, Deglise, S, Bellmunt-Montoya, S, Hofer, S, Yusuf, S, Ronchey, S, Bartoli, S, Bonvini, S, Camparini, S, Fazzini, S, Pirrelli, S, Hörer, T, Bisdas, T, Vasudevan, T, Lattmann, T, Wyss, T, Maldonado, T, Pfammatter, T, Kölbel, T, Jakimowicz, T, Donati, T, Tracci, M, Bracale, U, Tolva, V, Riambau, V, Palazzo, V, Makaloski, V, Regula S, V, Dorigo, W, Mansour, W, Van den Eynde, W, Tinelli, Giovanni, D’Oria, Mario, Sica, Simona, Mani, Kevin, Rancic, Zoran, Resh, Timothy Andrew, Beccia, Flavia, Azizzadeh, Ali, Da Volta Ferreira, Marcelo Martins, Gargiulo, Mauro, Lepidi, Sandro, Tshomba, Yamume, Oderich, Gustavo S., Haulon, Stephan, Beck, Adam W., Hertault, Adrien, Savlania, Ajay, Froio, Alberto, Giaquinta, Alessia, Zimmermann, Alexander, Psyllas, Anastasios, Wanhainen, Anders, Marchetti, Andrea Ascoli, Queiroz, Andre Brito, Kahlberg, Andrea, Reyes-Valdivia, Andrés, Schanzer, Andres, Edinburgh Vascular, Andrew Tambyraja, Freyrie, Antonio, Lorido, Antonio, Millon, Antoine, Ippoliti, Arnaldo, Abai, Babak, Mees, Barend, Reutersberg, Benedikt, Maurel, Blandine, Michel, Bosiers, Wahlgren, Carl Magnus, Cavazzini, Carlo, Setacci, Carlo, Lee, Cheong Jun, Ferrer, Ciro, Bicknell, Colin, Raphaël, Coscas, Clair, Daniel, Dawson, David L., Arnaoutakis, Dean J., Böckler, Dittmar, Kotelis, Drosos, Mujagic, Edin, Chisci, Emiliano, Cieri, Enrico, Gallitto, Enrico, Marone, Enrico Maria, Ducasse, Eric, Verzini, Fabio, Pecoraro, Felice, Serracino-Inglott, Ferdinand, Benedetto, Filippo, Speziale, Francesco, Stilo, Francesco, Álvarez-Marcos, Francisco, Pagliariccio, Gabriele, Piffaretti, Gabriele, Lanza, Gaetano, Philipp, Geisbüsch, Geenberg, George, Jung, Georg, Melissano, Germano, Veraldi, Gian Franco, Parlani, Gianbattista, Faggioli, Gianluca, de Donato, Gianmarco, Simonte, Gioele, Colacchio, Giovanni, De Caridi, Giovanni, Pratesi, Giovanni, Spinella, Giovanni, Torsello, Giovanni, Leong Tan, Glenn Wei, Magee, Gregory A., Verhagen, Hence, Andrew, Holden, Koleilat, Issam, Ohman, J Westley, de Vries, J. P. P. M., Budtz-Lilly, Jacob, Black, James, Eldrup-Jorgensen, Jens, Hockley, Joe, Bath, Jonathan, Sobocinski, Jonathan, van Herwaarden, Joost A., Reinhard, Kopp, Orion, Kristine C., Amankwah, Kwame, Bertoglio, Luca, di Marzo, Luca, Garriboli, Luca, Rizzo, Luigi, Hakimi, Maani, Sheahan, Malachi, Khashram, Manar, Schermerhorn, Marc, Lescan, Mario, Conrad, Mark, Davies, Mark G., Czerny, Martin, Orrico, Matteo, Eagleton, Matthew J., Smeds, Matthew R., Taurino, Maurizio, Wohlauer, Max, Sharafuddin, Mel J., Anna-Leonie, Menges, Reijnen, Michel, Antonello, Michele, Piazza, Michele, Settembre, Nicla, Mouawad, Nicolas J., Tsilimparis, Nikolaos, Dias, Nuno, Martinelli, Ombretta, Frigatti, Paolo, Sirignano, Pasqualino, Chong, Patrick, Bevis, Paul, DiMuzio, Paul, Henke, Peter, Düppers, Philip, Holt, Peter, Helmiö, Päivi, Vriens, Patrick, Pulli, Raffaele, Bellosta, Raffaello, Micheli, Raimondo, Veeraswamy, Ravi, Cuff, Robert, Chiappa, Roberto, Gattuso, Roberto, Pini, Rodolfo, Dalman, Ronald L., Milner, Ross, Scali, Salvatore T., Bahia, Sandeep, Laukontaus, Sani, Trimarchi, Santi, Fernandez-Alonso, Sebastian, Deglise, Sebastien, Bellmunt-Montoya, Sergi, Hofer, Simone, Yusuf, Syed W., Ronchey, Sonia, Bartoli, Stefano, Bonvini, Stefano, Camparini, Stefano, Fazzini, Stefano, Pirrelli, Stefano, Hörer, Tal, Bisdas, Theodosios, Vasudevan, Thodur, Lattmann, Thomas, Wyss, Thomas Rudolf, Maldonado, Thomas, Pfammatter, Thomas, Kölbel, Tilo, Jakimowicz, Tomasz, Donati, Tommaso, Tracci, Margaret, Bracale, Umberto Marcello, Tolva, Valerio Stefano, Riambau, Vincent, Palazzo, Vincenzo, Makaloski, Vladimir, Regula S, Von Allmen, Dorigo, Walter, Mansour, Wassim, and Van den Eynde, Wouter

Abstract

Objective: Management of follow-up protocols after endovascular aortic repair (EVAR), vary significantly between centres and is not standardized according to the sac regression. By designing an international expert-based Delphi consensus, the study aimed to create recommendations on follow-up after EVAR according to sac evolution. Methods: Eight facilitators created appropriate statements regarding the study topic that were voted, using a 4-point Likert scale, by a selected panel of international experts using a three-round modified Delphi consensus process. Based on the experts' responses, only those statements reaching a Grade A (full agreement ≥75%) or B (overall agreement ≥80% and full disagreement <5%) were included in the final document. Results: One-hundred and seventy-four participants were included in the final analysis, and each voted the initial 29 statements related to the definition of sac regression (Q1-Q9), EVAR follow-up (Q10-Q14), and the assessment and role of sac regression during follow-up (Q15-Q29). At the end of the process, 2 statements (6.9%) were rejected, 9 statements (31%) received a grade B consensus strength, and 18 (62.1%) reached a grade A consensus strength. Out of twenty-seven final statements, fifteen statements (55.6%) were classified as grade I, while twelve (44.4%) were classified as grade II. Experts agreed that sac regression should be considered an important indicator of EVAR success and always be assessed during follow-up after EVAR. Conclusions: Based on the elevated strength and high consistency of this international expert-based Delphi consensus, most of the statements might guide current clinical management of follow-up after EVAR according to the sac regression. Future studies are needed to clarify debated issues.

Published
2024

15. Novel Textbook Outcomes following emergency laparotomy:Delphi exercise

Author

Naumann, David N., Bhangu, Aneel, Brooks, Adam, Martin, Matthew, Cotton, Bryan A., Khan, Mansoor, Midwinter, Mark J., Pearce, Lyndsay, Bowley, Douglas M., Holcomb, John B., Griffiths, Ewen A., Abu-Abeid, Adam, Peckham-Cooper, Adam, Dyas, Adam R., Adeyeye, Ademola, Dogjani, Agron, Ball, Alasdair C.Y., Wolthuis, Albert M., Quiroga-Garza, Alejandro, Karamarkovic, Aleksandar R., Giordano, Alessio, Fuchs, Alexander, Julianov, Alexander, Phillips, Alexander W., Zimmermann, Alexander, Charalabopoulos, Alexandros, Birkun, Alexei A., Narvaez-Rojas, Alexis Rafael, Guner, Ali, Fayed, Aly, Davis, Amelia L., Vereczkei, Andras, Balla, Andrea, Celotti, Andrea, Romanzi, Andrea, Trombetta, Andrea, Beggs, Andrew D., Robertson, Andrew G., Petrosoniak, Andrew, Davies, Andrew R., Becerra-Bolaños, Ángel, Loria, Anthony, Brillantino, Antonio, Athanasiou, Antonios, Isik, Arda, Ioannidis, Argyrios, Santos, Ariel P., Saha, Arin K., Wijnhoven, Bas P.L., Liu, David S., Naumann, David N., Bhangu, Aneel, Brooks, Adam, Martin, Matthew, Cotton, Bryan A., Khan, Mansoor, Midwinter, Mark J., Pearce, Lyndsay, Bowley, Douglas M., Holcomb, John B., Griffiths, Ewen A., Abu-Abeid, Adam, Peckham-Cooper, Adam, Dyas, Adam R., Adeyeye, Ademola, Dogjani, Agron, Ball, Alasdair C.Y., Wolthuis, Albert M., Quiroga-Garza, Alejandro, Karamarkovic, Aleksandar R., Giordano, Alessio, Fuchs, Alexander, Julianov, Alexander, Phillips, Alexander W., Zimmermann, Alexander, Charalabopoulos, Alexandros, Birkun, Alexei A., Narvaez-Rojas, Alexis Rafael, Guner, Ali, Fayed, Aly, Davis, Amelia L., Vereczkei, Andras, Balla, Andrea, Celotti, Andrea, Romanzi, Andrea, Trombetta, Andrea, Beggs, Andrew D., Robertson, Andrew G., Petrosoniak, Andrew, Davies, Andrew R., Becerra-Bolaños, Ángel, Loria, Anthony, Brillantino, Antonio, Athanasiou, Antonios, Isik, Arda, Ioannidis, Argyrios, Santos, Ariel P., Saha, Arin K., Wijnhoven, Bas P.L., and Liu, David S.

Abstract

Background: Textbook outcomes are composite outcome measures that reflect the ideal overall experience for patients. There are many of these in the elective surgery literature but no textbook outcomes have been proposed for patients following emergency laparotomy. The aim was to achieve international consensus amongst experts and patients for the best Textbook Outcomes for non-trauma and trauma emergency laparotomy. Methods: A modified Delphi exercise was undertaken with three planned rounds to achieve consensus regarding the best Textbook Outcomes based on the category, number and importance (Likert scale of 1–5) of individual outcome measures. There were separate questions for non-trauma and trauma. A patient engagement exercise was undertaken after round 2 to inform the final round. Results: A total of 337 participants from 53 countries participated in all three rounds of the exercise. The final Textbook Outcomes were divided into ‘early’ and ‘longer-term’. For non-trauma patients the proposed early Textbook Outcome was ‘Discharged from hospital without serious postoperative complications (Clavien–Dindo ≥ grade III; including intra-abdominal sepsis, organ failure, unplanned re-operation or death). For trauma patients it was ‘Discharged from hospital without unexpected transfusion after haemostasis, and no serious postoperative complications (adapted Clavien–Dindo for trauma ≥ grade III; including intra-abdominal sepsis, organ failure, unplanned re-operation on or death)’. The longer-term Textbook Outcome for both non-trauma and trauma was ‘Achieved the early Textbook Outcome, and restoration of baseline quality of life at 1 year’. Conclusion: Early and longer-term Textbook Outcomes have been agreed by an international consensus of experts for non-trauma and trauma emergency laparotomy. These now require clinical validation with patient data.

Published
2024

16. An Expert-Based Review on the Relevance and Management of Type 2 Endoleaks Following Endovascular Repair of Ruptured Abdominal Aortic Aneurysms.

Author

Dueppers, Philip, D'Oria, Mario, Lepidi, Sandro, Calvagna, Cristiano, Zimmermann, Alexander, and Kopp, Reinhard

Subjects
ABDOMINAL aortic aneurysms, ENDOVASCULAR aneurysm repair, AORTIC aneurysms, ENDOVASCULAR surgery, THERAPEUTIC embolization, AORTIC rupture
Abstract

Ruptured abdominal aortic aneurysms (rAAAs) are life-threatening and require emergent surgical therapy. Endovascular aortic repair for rupture (rEVAR) has become the leading strategy due to its minimal invasive approach with expected lower morbidity and mortality, especially in patients presenting with hemodynamic instability and relevant comorbidities. Following rEVAR, intraoperative angiography or early postinterventional computed tomography angiography have to exclude early type 1 or 3 endoleaks requiring immediate reintervention. Persistent type 2 endoleaks (T2ELs) after rEVAR, in contrast to elective cases, can cause possibly lethal situations due to continuing extravascular blood loss through the remaining aortic aneurysm rupture site. Therefore, early identification of relevant persistent T2ELs associated with continuous bleeding and hemodynamic instability and immediate management is mandatory in the acute postoperative setting following rEVAR. Different techniques and concepts for the occlusion of T2ELs after rEVAR are available, and most of them are also used for relevant T2ELs after elective EVAR. In addition to various interventional embolization procedures for persistent T2ELs, some patients require open surgical occlusion of T2EL-feeding arteries, abdominal compartment decompression or direct surgical patch occlusion of the aneurysm rupture site after rEVAR. So far, in the acute situation of rAAAs, indications for preemptive or intraoperative T2EL embolization during rEVAR have not been established. In the long term, persistent T2ELs after rEVAR can lead to continuous aneurysm expansion with the possible development of secondary proximal type I endoleaks and an increased risk of re-rupture requiring regular follow-up and early consideration for reintervention. To date, only very few studies have investigated T2ELs after rEVAR or compared outcomes with those from elective EVAR regarding the special aspects of persisting T2ELs. This narrative review is intended to present the current knowledge on the incidence, natural history, relevance and strategies for T2EL management after rEVAR. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

19. Präventives Wassermanagement – Teil II.

Author

Kittemann, Dominikus, Beck, Michael, Werth, Johannes, Haug, Anna Lena, Biegert, Konni, Killer, Annika, Zimmermann, Alexander, and Kuster, Thomas

Subjects
STORM water retention basins, SOILS, SOIL moisture, WOOD chips, TEXTILES
Abstract

The article presents the discussion on effect of soil additives on improving water retention capacity in the soil and thus enhancing water availability for plants. Topics include experiments was to reduce soil evaporation and thereby contribute to improved soil moisture; and materials included organic mulches such as wood chips, bark mulch, and straw, as well as synthetic mulches like plastic film and non-woven fabrics.

Published
2024

20. Präventives Wassermanagement.

Author

Kittemann, Dominikus, Beck, Michael, Werth, Johannes, Haug, Anna Lena, Biegert, Konni, Killer, Annika, Zimmermann, Alexander, and Kuster, Thomas

Subjects
WATER management, ORCHARDS, RAINFALL, WATER use
Abstract

The article focuses on preventive water management in orchards, addressing the challenges posed by changing precipitation patterns and emphasizing the need for efficient water utilization. It summarizes a three-year project conducted at four different locations in Germany, exploring ways to enhance water availability in orchards and optimize the utilization of natural rainfall.

Published
2024

23. Paradoxical Leadership: An Integrative Review and Future Research Agenda.

Author

Zivkovic, Djordje, Langenbacher, Mirjam, and Zimmermann, Alexander

Abstract

Research on paradoxical leadership (PL), defined as leaders' seemingly contradictory, yet interrelated behaviors that entail a 'both-and' approach to address tensions has gained increasing momentum in recent years. However, to date, there is no literature review that integrates the partly disconnected research streams and cumulates empirical findings. In this article, we distinguish between different types of paradoxical tensions on multiple levels of analysis and discuss individual and organizational management approaches to cope with these tensions. By doing so, we extend the notion of PL to the management of paradoxes on the individual and organizational level. Based on our framework, we discuss shortcomings and gaps with respect to the interplay of drivers, different levels of analysis as well as boundaries and outcomes and present an agenda for future research that contributes to a more holistic understanding of PL. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

24. iCover as Bridging Stent Graft in Fenestrated Endovascular Aortic Aneurysm Repair

Author

Menges, Anna-Leonie, Landré, Vincent, Meuli, Lorenz, Zimmermann, Alexander, and Reutersberg, Benedikt

Abstract

Background: Complex endovascular repair with fenestrated or branched stent grafts is a common approach for treating various types of aortic aneurysms. Bridging stent grafts (BSs) are crucial in connecting aortic endoprosthesis to target vessels, yet current options have demonstrated significant complications.Objective: This retrospective single-center study evaluates the initial outcomes and durability of the iCover stent graft (iCover-SG) when used as a BS in fenestrated endovascular aneurysm repair (FEVAR).Methods: Retrospective analysis screened procedures for complex aortic aneurysms between August 2021 and January 2024. Patients who underwent FEVAR with iCover-SG as BS were included. Primary and secondary endpoints focused on freedom from iCover-SG-related target vessel instability, technical success, and postoperative outcomes.Results: Within the cohort of 28 patients, 94 iCover-SGs were used as BS, supplying 87 target vessels. The freedom from iCover-SG-related target vessel instability throughout the study reached 94% (82/87). Technical success rates were notably high, with primary success achieved in 94% of cases and secondary success in 99%. Over the follow-up duration, there were instances necessitating reintervention related to iCover-SG, including 4 cases of endoleak, 2 cases of T1cEL, and 2 cases of T3cEL. In-hospital mortality was 7% (n=4), with 2 cases attributed to intraoperative complications. Importantly, no deaths were directly attributed to iCover-SG-related issues.Conclusion: The iCover-SG demonstrates promising initial outcomes as a BS in FEVAR, with high technical success rates and satisfactory rates of target vessel instability. Continued monitoring and further studies are warranted to assess long-term durability and outcomes.Clinical Impact This study shows that the iCover stent graft achieves satisfactory technical success and target vessel stability in the short- and mid-term when used as a bridging stent graft in FEVAR procedures. Its successful integration into clinical practice broadens the range of available options, providing clinicians with more versatile tools for managing complex endovascular aortic aneurysms. This expanded selection of bridging stent grafts allows for more personalised treatment strategies, improving procedural precision and patient outcomes. The iCover stent graft’s reliable performance highlights its potential as a valuable addition to current endovascular techniques, ultimately enhancing patient care in challenging cases.

Published
2024
Full Text
View/download PDF

25. An International Expert-Based CONsensus on Indications and Techniques for aoRtic balloOn occLusion in the Management of Ruptured Abdominal Aortic Aneurysms (CONTROL-RAAA)

Author

D’Oria, Mario, Lembo, Rosalba, Hörer, Tal M., Rasmussen, Todd, Mani, Kevin, Parlani, Gianbattista, Ierardi, Anna Maria, Veraldi, Gian Franco, Melloni, Andrea, Bonardelli, Stefano, Lepidi, Sandro, Bertoglio, Luca, Antonello, Michele, Mees, Barend, Bath, Jonathan, Goncalves, Frederico Bastos, Beck, Adam W, Bellmunt, Sergi, Berard, Xavier, Bose, Joseph Du, Budtz-Lilly, Jacob, Calvagna, Cristiano, Czerny, Martin, Dawson, David, McGreevy, David T, Greenberg, George, Savlania, Ajay, Davies, Mark G, Dias, Nuno, Farber, Mark A, Fajer, Simone, Ferreira, Marcelo, Franchin, Marco, Gallitto, Enrico, Goldin, Ilya, Jakimowicz, Tomasz, van Herzeele, Isabelle, Hockley, Joseph A, Holden, Andrew, Kahlberg, Andrea, Charlton-Ouw, Kristofer M, Khashram, Manar, Kotelis, Drosos, Giacomo, Isernia, Maldonado, Thomas S, Magee, Gregory, Maurel, Blandine, Mezzetto, Luca, Milner, Ross, Panuccio, Giuseppe, Helmio, Paivi, Pratesi, Giovanni, Reijnen, Michel M P J, Resch, Timothy, Riambau, Vincente, Starnes, Benjamin, Settembre, Nicla, Smeds, Matthew R., Scali, Salvatore, Psyllas, Anastasios, Sobocinski, Jonathan, Guliani, Sundeep, Tan, Glenn Wei Leong, Tinelli, Giovanni, Tsilimparis, Nikolaos, Trimarchi, Santi, Vriens, Patrick, Wahlgren, Carl, Van den Eynde, Wouter, Vasudevan, Thodur, Verhagen, Hence JM, Zacà, Sergio, Troisi, Nicola, Wanhainen, Anders, Witheford, Miranda, and Zimmermann, Alexander

Abstract

Objective: To report on the recommendations of an expert-based consensus on the indications, timing, and techniques of aortic balloon occlusion (ABO) in the management of ruptured abdominal aortic aneurysms (rAAA).Methods: Eleven facilitators created appropriate statements regarding the study issues that were voted on using a 4-point Likert scale with open-comment fields, by a selected panel of international experts (vascular surgeons and interventional radiologists) using a 3-round modified Delphi consensus procedure (study period: January-April 2023). Based on the experts’ responses, only the statements reaching grade A (full agreement ≥75%) or B (overall agreement ≥80% and full disagreement <5%) were included in the final study report. The consistency of each round’s answers was also graded using Cohen’s kappa, the intraclass correlation coefficient, and, in case of double resubmission, Fleiss kappa.Results: Sixty-three experts were included in the final analysis and voted on 25 statements related to indication and timing (n=6), and techniques (n=19) of ABO in the setting of rAAA. Femoral sheath or ABO should be preferably placed in the operating room, via a percutaneous transfemoral access, on a stiff wire (grade B, consistency I), ABO placement should be suprarenal and last less than 30 minutes (grade B, consistency II), postoperative peripheral vascular status (grade A, consistency II) and laboratory testing every 6 to 12 hours (grade B, consistency) should be assessed to detect complications. Formal training for ABO should be implemented (grade B, consistency I). Most of the statements in this international expert-based Delphi consensus study might guide current choices for indications, timing, and techniques of ABO in the management of rAAA. Clinical practice guidelines should incorporate dedicated statements that can guide clinicians in decision-making.Conclusions: At arrival and during both open or endovascular procedures for rAAA, selective use of intra-aortic balloon occlusion is recommended, and it should be performed preferably by the treating physician in aortic pathology.Clinical Impact This is the first consensus study of international vascular experts aimed at defining the indications, timing, and techniques of optimal use of ABO in the clinical setting of rAAA. Aortic occlusion by endovascular means (or ABO) is a quick procedure in properly trained hands that may play an important role as a temporizing measure until the definitive aortic repair is achieved, whether by endovascular or open means. Since data on its use in hemodynamically unstable patients are limited in the literature, owing to practical challenges in the performance of well-conducted prospective studies, understanding real-world use by experts is of importance in addressing critical issues and identifying main gaps in knowledge.

Published
2024
Full Text
View/download PDF

26. Rational correction of pathogenic conformational defects in HTRA1.

Author

Beaufort N, Ingendahl L, Merdanovic M, Schmidt A, Podlesainski D, Richter T, Neumann T, Kuszner M, Vetter IR, Stege P, Burston SG, Filipovic A, Ruiz-Blanco YB, Bravo-Rodriguez K, Mieres-Perez J, Beuck C, Uebel S, Zobawa M, Schillinger J, Malik R, Todorov-Völgyi K, Rey J, Roberti A, Hagemeier B, Wefers B, Müller SA, Wurst W, Sanchez-Garcia E, Zimmermann A, Hu XY, Clausen T, Huber R, Lichtenthaler SF, Schmuck C, Giese M, Kaiser M, Ehrmann M, and Dichgans M

Subjects
Animals, Humans, Mice, Protein Conformation, Protein Multimerization, HEK293 Cells, Brain metabolism, Brain pathology, Mutation, Loss of Function Mutation, High-Temperature Requirement A Serine Peptidase 1 metabolism, High-Temperature Requirement A Serine Peptidase 1 genetics
Abstract

Loss-of-function mutations in the homotrimeric serine protease HTRA1 cause cerebral vasculopathy. Here, we establish independent approaches to achieve the functional correction of trimer assembly defects. Focusing on the prototypical R274Q mutation, we identify an HTRA1 variant that promotes trimer formation thus restoring enzymatic activity in vitro. Genetic experiments in Htra1 R274Q mice further demonstrate that expression of this protein-based corrector in trans is sufficient to stabilize HtrA1-R274Q and restore the proteomic signature of the brain vasculature. An alternative approach employs supramolecular chemical ligands that shift the monomer-trimer equilibrium towards proteolytically active trimers. Moreover, we identify a peptidic ligand that activates HTRA1 monomers. Our findings open perspectives for tailored protein repair strategies., (© 2024. The Author(s).)

Published
2024
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results