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Abstract Here, based on thin film integrated passive device (TF‐IPD) technology, compact ultra‐wideband (UWB) bandpass filter (BPF) and dual‐band bandpass filter (DBBPF) with equal inductance configuration are proposed. The configuration of equal inductance in a circuit contributes to reducing variables, simplifying the physical structure, and shortening the debugging time in the TF‐IPD design process. Despite all the inductors being equal in value, a wide passband can still be achieved. The measured results show that the centre frequency of UBW BPF is 11.43 GHz, and the 3‐dB fractional bandwidth (FBW) is 133% (3.87–18.99 GHz). And the 3‐dB FBWs of DBBPF centred at 6.5 GHz and 16.2 GHz are 92% (3.51–9.49 GHz) and 35% (13.33–18.98 GHz), respectively. The stopband of UBW BPF and DBBPF can be extended to 47.7 GHz and 44.8 GHz in sizes of 321 µm × 856 µm and 235 µm × 846 µm, respectively (excluding measuring pads).

Immunosenescence contributes to systematic aging and plays a role in the pathogenesis of Alzheimer's disease (AD). Therefore, the objective of this study was to investigate the potential of immune rejuvenation as a therapeutic strategy for AD. To achieve this, the immune systems of aged APP/PS1 mice were rejuvenated through young bone marrow transplantation (BMT). Single-cell RNA sequencing revealed that young BMT restored the expression of aging-and AD-related genes in multiple cell types within blood immune cells. The level of circulating senescence-associated secretory phenotype proteins was decreased following young BMT. Notably, young BMT resulted in a significant reduction in cerebral Aß plaque burden, neuronal degeneration, neuroinflammation, and improvement of behavioral deficits in aged APP/PS1 mice. The ameliorated cerebral amyloidosis was associated with an enhanced Aß clearance of peripheral monocytes. In conclusion, our study provides evidence that immune system rejuvenation represents a promising therapeutic approach for AD. [ABSTRACT FROM AUTHOR]