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Due to the use of lumbar folding steering for heavy-duty articulated vehicles in coal mines, the lateral stiffness is weak and the disturbance factors are complex, making it more difficult to operate and easily causing safety problems. A new pump controlled electro-hydraulic steering system with lateral motion feedback compensation was proposed to improve the safe driving and handling performance of coal mine heavy-duty articulated vehicles in wet and low adhesion road environments, and further enhance the intelligent level of coal mine auxiliary transportation. A four-degree-of-freedom dynamics model of articulated vehicle and a mathematical model of pump-controlled electro-hydraulic steering system were established, including front body longitudinal, lateral, yaw and rear body yaw motion. Based on the yaw velocity and lateral acceleration of the decoupling dynamics model, the two-channel articulated steering control strategy of “steering control follow - yaw stability compensation” was designed. The steering control follow channel can realize the real-time tracking of the steering input of the driver by the articulated angle. The yaw stability compensation channel ensures that the actual yaw velocity is close to the ideal yaw velocity by actively adjusting the articulated angle. By setting up a pre-filters and attenuation integrator, an active steering control system was designed, which provides corrective action by adjusting the steering angle to ensure that the vehicle can follow the driver's intention and maintain path following. Based on the dSPACE/DS1007 semi physical simulation platform, some simulation tests were conducted on the low adhesion steering conditions of articulated mining vehicles. The effectiveness of the active controller for tracking the desired path of articulated vehicles was verified by simulating the J-shaped turning condition and selecting the low friction coefficient road conditions for the medium to low speed operation. Meanwhile, based on the experimental conditions of equivalent low adhesion coefficient road surface covered with ice and snow, a 25 t coal mine heavy-duty articulated support truck was used for actual vehicle turning experiments. The results show that the dynamics model of articulated vehicle and a mathematical model of pump-controlled electro-hydraulic steering system established can truly reflect the lumbar folding motion state of this type of vehicle by decoupling the yaw rate and lateral acceleration. The two-channel articulated steering control strategy of "steering control follow - yaw stability compensation" based on the analysis of articulated vehicle yaw stability control, as well as the designed active control system, can effectively improve the lateral stability of articulated vehicles under low adhesion coefficient road conditions, and the system has not changed the driver's driving experience, and after active control intervention, it can timely, safely, and smoothly hand over the vehicle's driving rights to the driver.

ObjectiveGiven the limited evidence on the relationship between the triglyceride-glucose (TyG) index and the risk of prediabetes among young adults, our study aimed to investigate the potential impact of the TyG index on the future development of prediabetes in young individuals.MethodsThis retrospective cohort study included 125,327 healthy adults aged 20 to 45 years. We utilized Cox proportional hazards regression models, combined with cubic spline functions and smooth curve fitting, to assess the relationship between baseline TyG index and the risk of prediabetes among young adults, exploring its non-linear association. A series of sensitivity analyses and subgroup analyses were conducted to ensure the robustness of our findings.ResultsAfter adjusting for covariates, the study found a positive correlation between the TyG index and the risk of prediabetes (HR=1.81, 95%CI: 1.54–2.13, p

ObjectivePrevious studies have confirmed a positive correlation between the Triglyceride-Glucose (TyG) index and future risk of diabetes. However, evidence of this association in non-obese young populations remains limited. This study aims to investigate the relationship between the TyG index and the future risk of diabetes among non-obese young adults.MethodsThis retrospective cohort study included 113,509 non-obese young adults from China and 9,549 from Japan. The mean age was 35.73 ± 6.38 years, and 56,469 participants (45.89%) were male. The median follow-up duration was 3.38 years. The association between baseline TyG index and risk of diabetes was examined using Cox proportional hazards regression models. Non-linear relationships between the TyG index and risk of diabetes were identified using cubic splines and smoothed curve fitting in the Cox models. Sensitivity and subgroup analyses were also conducted.ResultsAfter adjusting for covariates, the results indicated a positive correlation between the TyG index and risk of diabetes in non-obese young adults (HR=3.57, 95% CI: 2.92-4.36, P

Abstract Previous research has established a strong link between pulse pressure (PP) and diabetes, but there is limited investigation into the connection between PP and prediabetes. This study aims to explore the potential association between PP and prediabetes. A retrospective cohort study encompassed 202,320 Chinese adults who underwent health check-ups between 2010 and 2016. Prediabetes was defined in accordance with the World Health Organization criteria, indicating impaired fasting glucose, with fasting blood glucose levels ranging from 6.1 to 6.9 mmol/L. To assess the PP-prediabetes relationship, we employed Cox regression analysis, sensitivity analysis, and subgroup analysis. Cox proportional hazards regression, coupled with cubic spline functions and smooth curve fitting, helped elucidate the non-linear PP-prediabetes relationship. Upon adjusting for confounding factors, we observed a positive association between PP and prediabetes (HR 1.15, 95% CI 1.11–1.18, P

Abstract This study aimed to investigate the relationship between platelet count (PC) and mortality in patients with hemorrhagic stroke (HS). The research reviewed data from 10,466 patients hospitalized in 208 hospitals in the United States from January 1, 2014, to December 31, 2015. Of these, 3262 HS patients were included in the primary analysis for those admitted to the intensive care unit (ICU). The average age of these patients was 67.05 years, with 52.79% being male. The median PC was (221.67 ± 73.78) × 109/L. Multivariate logistic regression analysis revealed that PC was a protective factor for mortality in HS patients (OR = 0.98, 95% CI 0.97–1.00, P

Abstract This primary objective of our study was to investigate the relationship between serum calcium levels and the occurrence of sudden cardiac arrest (SCA) in stroke patients. We analyzed the clinical data of 10,423 acute stroke patients admitted to the intensive care unit. The association between serum calcium and SCA following an acute stroke was assessed through multivariate logistic regression. We explored the non-linear connection between serum calcium levels and SCA in stroke patients using a generalized additive model and smooth curve fitting. Our study uncovered that serum calcium serves as an independent risk factor for sudden cardiac arrest in stroke patients. Notably, we observed that the relationship between serum calcium levels upon admission and the occurrence of SCA in stroke patients within the hospital was non-linear. Furthermore, we identified inflection points in serum calcium levels at 8.2 and 10.4 mg/dL. These findings emphasize a non-linear relationship between serum calcium levels and the risk of SCA in stroke patients. Maintaining serum calcium within the range of 8.2–10.4 mg/dL could lead to a significant reduction in the incidence of cardiac arrest among stroke patients.

BackgroundThe red blood cell distribution width (RDW) is closely linked to the prognosis of multiple diseases. However, the connection between RDW and gastrointestinal bleeding (GIB) in stroke patients is not well understood. This study aimed to clarify this association.MethodsThis retrospective study involved 11,107 hospitalized patients from 208 hospitals in the United States, admitted between January 1, 2014, and December 31, 2015. We examined clinical data from 7,512 stroke patients in the intensive care unit (ICU). Multivariate logistic regression assessed the link between RDW and in-hospital GIB in stroke patients. Generalized additive model (GAM) and smooth curve fitting (penalty spline method) were utilized to explore the non-linear relationship between RDW and GIB in stroke patients. The inflection point was calculated using a recursive algorithm, and interactions between different variables were assessed through subgroup analyses.ResultsAmong the 11,107 screened stroke patients, 7,512 were included in the primary analysis, with 190 identified as having GIB. The participants had a mean age of (61.67 ± 12.42) years, and a median RDW of 13.9%. Multiple logistic analysis revealed RDW as a risk factor for in-hospital GIB in stroke patients (OR = 1.28, 95% CI 1.21, 1.36, p

Wave energy conversion holds promise for renewable energy, but challenges like high initial costs hinder commercialization. Integrating wave-energy converters (WECs) into shore-protection structures creates dual-function structures for both electricity generation and coastal protection. Oscillating water columns (OWCs) have been well studied in the past with their simple generation mechanism and their out-of-water power take-off (PTO) system, which can minimize bio-fouling effects and maintenance costs compared to other submerged WECs. In addition, a slotted barrier allows for better circulation behind the breakwater while dissipating incoming wave energy through viscous damping. This study examines the performance of a new design which combines an OWC with a slotted breakwater. Small-scale (1:49) laboratory tests were performed with a piston-type wave generator. The performance is evaluated in terms of wave transmission, wave energy extraction, and wave loading under various wave conditions while focusing on the effects of the porosity of the slotted barrier and tide level changes. Results show that under larger waves, a decreasing wave transmission, increasing power extraction from the OWC, and energy dissipation from the slotted barrier are observed. On the other hand, under increasing wavelengths, wave transmission is observed to be constant; this is important for harbor design, which means that the breakwater is effective under a wider range of wavelengths. Porosity allows for more transmission while inducing less horizontal force on the structure.