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The computation offloading problem in mobile edge computing (MEC) has received a lot of attention, but service caching is also a research topic that cannot be ignored in MEC. Due to the limited resources available on the Edge Server (ES), a wise computation offloading and service caching policy must be formulated in order to maximize system offload efficiency. In this paper, a many-objective joint optimization computation offloading and service caching model (MaJOCOSC) is designed. The model takes into account the limited computing and storage resources of ES, the delay and energy consumption constraints of different types of tasks, and multiple processing modes of user tasks, and sets delay, energy consumption, task hit service rate, service cache balancing, and load balancing as the five optimization objectives of MaJOCOSC. Meanwhile, a non-dominated sorting genetic algorithm (NSGAIII-ASF&WD) based on achievement scalar function (ASF) and the k-nearest neighbor weighted distance mating selection strategy is proposed for better solving the model. The ASF ensures that the given strategy performs well for each objective value, and the k-nearest neighbor weighted distance provides the user with a diversity of strategies. Simulation results show that NSGAIII-ASF&WD can obtain better objective values when solving the model compared with other many-objective evolutionary algorithms, and a suitable computation offloading and service caching strategy is obtained. [ABSTRACT FROM AUTHOR]

Herein, we have developed a novel single-molecular probe (NORP) for selective and accurate determination of NTR in living cells. It was discovered that up-regulation of endogenous NTR occurred in response to hypoxic stimulation, and there was a dependence between the NTR levels and the degree of hypoxia. [ABSTRACT FROM AUTHOR]

The effect of surface roughness on the interfacial contact resistance (ICR) and the corrosion behavior of 446 stainless steel in simulated anode environments for proton exchange membrane fuel cell (PEMFC) (i.e., 0.5 mol L−1 H2SO4 + 2 ppm F− and 5 × 10−4 mol L−1 H2SO4 + 0.1 ppm F− bubbled with hydrogen gas at 80 °C) was investigated by means of atomic force microscopy, potentiodynamic polarization, electrochemical impedance spectroscopy and ICR test. The surface roughness (Ra) produced by mechanical grinding increases noticeably with the decrease of sandpaper grit size from 1000# to 240#. 446 stainless steel shows the active state under free corrosion conditions in the two test solutions and the passive state at the typical anode working potential of PEMFC after the activation-passivation transition. The corrosion resistance decreases with the increase of roughness in both solutions. The corrosion product films formed in the solution with lower acidity are more protective, leading to the appearance of the diffusion process. The enlargement of surface roughness results in the gradual reduction of ICR, but the acceleration of active and passive dissolutions. [ABSTRACT FROM AUTHOR]