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By confining light into a deep subwavelength scale to match the characteristic dimension of quantum emitters, plasmonic nanocavities can effectively imprint the light emission with unique properties in terms of intensity, directionality, as well as polarization. In this vein, achiral quantum emitters can generate chiral photons through coupling with plasmonic nanocavities with either intrinsic or extrinsic chirality. As an important metric for the chiral-photon purity, the degree of circular polarization (DCP) is usually tuned by various scattered factors such as the nanocavity design, the emitter type, and the coupling strategy. The physical mechanisms of the chiral photon generation, especially when plasmons and emitters step into the strong coupling regime, are less explored. In this paper, we extended the coupled-oscillator and Jaynes–Cummings models to their chiral fashion to account for the above factors within a single theoretical framework and investigated the chiroptical properties of a plasmonic nanocavity-emitter hybrid system from weak to strong coupling. It was demonstrated that both the circular differential scattering and prominent scattering DCP rely on the intrinsic chirality generated by breaking the mirror symmetry with the emitter, and is thereby tunable by the coupling strength. However, the luminescence DCP (as high as 87 %) is closely related to the extrinsic chirality of the bare nanocavity and independent of the coupling strength. The results thus reveal two different physical mechanisms of generating chiral photons in scattering and luminescence. Our findings provide a theoretical guideline for designing chiral photon devices and contribute to the understanding of chiral plasmon-emitter interaction.

Potassium‐ion hybrid capacitors (PIHCs) are highly promising as an energy‐storage system. However, the rate performance and cycling performance of most materials with high capacity cannot simultaneously meet the requirements of PIHCs. In this work, a composite material of Bi2S3 nanoparticles in situ confined within a sulfur‐doped covalent organic framework (COF) and combined with graphene (Bi2S3@SCOF/G) is synthesized. Due to the synergistic effect of the stability of COF to buffer large mechanical stresses and the high electronic conductivity of graphene, the Bi2S3@SCOF/G anode reveals a high reversible capacity (503.8 mAh g−1 at 100 mA g−1 after 100 cycles) and favorable rate performance (223.9 mAh g−1 even at 5000 mA g−1). Furthermore, the PIHCs assembled with activated carbon show excellent energy density and cycling performance, indicating their potential for practical applications. [ABSTRACT FROM AUTHOR]

Background: Neoadjuvant (NE), adjuvant (AD), and perioperative (PE) immunotherapies have gained validation in early-stage non-small cell lung cancer (NSCLC) trials. However, a comprehensive assessment of their comparative efficacy and safety is lacking. Objectives: To compare the efficacy and safety of NE, AD, and PE immunotherapies in early-stage NSCLC. Design: A systematic review and network meta-analysis using a Bayesian framework. Data sources and methods: We searched PubMed, Embase, and Cochrane databases for randomized controlled trials (RCTs) of immune checkpoint inhibitors plus chemotherapy (CT) for early-stage NSCLC. Hazard ratios (HRs) and odds ratios (ORs) for binary endpoints with 95% confidence intervals (CIs) were calculated. Results: We included 10 RCTs involving 5569 NSCLC patients, categorized as NE, PE, or AD immunotherapy. Indirect comparisons highlighted differences in efficacy between PE and AD immunotherapy, specifically in event-free survival (EFS)/disease-free survival (DFS) (HR = 0.72, 95% CI: 0.53–0.96). NE/PE immunotherapies improved pathologic complete response (pCR) (OR = 7.56, 95% CI: 5.24–10.92), major pathologic response (MPR) (OR = 5.46, 95% CI: 3.97–7.51), and EFS (HR = 0.58, 95% CI: 0.52–0.65), while AD immunotherapy enhanced DFS (HR = 0.78, 95% CI: 0.69–0.90). Overall survival (OS) benefits were seen only with PE immunotherapy (HR = 0.66, 95% CI: 0.55–0.81). PE treatment improved EFS across various subgroups (PD-L1 < 1%, IIIB, squamous, female, without MPR/pCR, epidermal growth factor receptor (EGFR) mutant-negative), except EGFR mutant-positive NSCLC (HR = 0.54, 95% CI: 0.21–1.43). AD (OR = 1.81, 95% CI: 1.20–2.73) and PE (OR = 1.28, 95% CI: 1.10–1.50) immunotherapies were associated with higher grade ⩾3 adverse events. Conclusion: In the three treatment modalities, PE immunotherapy appears to be more effective than AD immunotherapy, with PE showing significant advantages in certain subgroups that NE does not. NE and PE immunotherapy significantly improved pCR, MPR, and EFS, while AD immunotherapy significantly improved DFS in NSCLC patients compared to the control group. However, only PE immunotherapy significantly improved OS. Differences in efficacy between NE and PE across the entire population of resectable NSCLC remain to be explored in additional studies. [ABSTRACT FROM AUTHOR]

Social media greatly facilitates people's access to information; however, it can also lead to information overload and exposure to uncomfortable content that may cause individuals to avoid it. As a result, two types of influencing mechanisms emerge: information exposure and information avoidance, which may impact users' behaviors. Currently, there is limited understanding of the simultaneous effects of social media information exposure and avoidance on individuals' behavioral intentions towards climate change mitigation. Using survey data for 1056 Chinese Gen-Z undergraduates and based on the extended theory of planned behavior, this paper utilizes a partial least squares structural equation model to examine the effects of social media information exposure and information avoidance on individual low-carbon behavioral intention. The results show that information exposure on social media has a positive relationship with behavioral attitude, subjective norm, and perceived behavioral control, and then increasing the low-carbon behavioral intention. Information avoidance has a negative association with three factors, respectively, and decreases the low-carbon behavioral intention. Additionally, exposure to social media information has the greatest impact on the subjective norm and the least impact on behavioral attitude; information avoidance has the greatest impact on behavioral attitude, whereas perceived behavioral control is the least affected. Drawing from the results, we propose policy recommendations that facilitate information exposure while addressing avoidance in shaping low-carbon behavioral intentions. Those implications would help reconcile the two opposing effects while promoting public engagement in climate activities. [ABSTRACT FROM AUTHOR]

High‐speed wide‐angle radio detection is crucial for intelligent wireless systems, autonomous vehicles, rescue operations in urgent situations, and security in various fields. This can be achieved through diverse controls of electromagnetic waves. Currently, multidimensional manipulations of electromagnetic waves are determined by dynamic antennas like phased arrays, mechanical beam‐steering radars, and programmable metasurface imagers. However, these methods face challenges in achieving rapid responses and large data collection intervals for high‐speed sensing and imaging, due to limitations in the speedy explication of analog‐to‐digital (AD) converters, electronic switches, phase shifters, and stepped motors for radiation beam reconfigurations. To address these challenges, advanced microwave‐to‐millimeter‐wave metasurfaces are introduced, designed to offer joint frequency, polarization, and spatial diversities. The metasurface with a disordered atom permutation enables wide‐angle sensing for accurate trajectory tracking of moving objects. On the other hand, a dispersion‐engineered atom arrangement allows the metasurfaces to facilitate wide‐angle through‐wall imaging, effective in detecting objects of varied shapes and positions. The experiments reveal that these metasurfaces can reconstruct objects at 100 frames per second (fps) from a single‐shot measurement, allowing 0.3x speed playback for detailed analysis. This demonstrates their potential in high‐speed sensing and imaging. Such a breakthrough is pivotal in unveiling new modalities and expanding possibilities in real‐time radio applications, including smart transportation, all‐condition surveillance, perspective radio, and integrated sensing and communication (ISAC) systems, especially relevant to technologies of 6G and beyond. [ABSTRACT FROM AUTHOR]

In this work, we demonstrate multi-channel GaN varactors with enhanced quality-factor (Q-factor) and cutoff frequency (f0) and present a comprehensive investigation of their current conduction mechanisms. The varactors were based on 1x-, 2x-, and 3x-channel GaN-on-SiC epitaxy with excellent channel conductivity, showing great enhancement of ∼270% both in Q-factor and in f0, thanks to the reduced resistance and capacitance by multi-channels in AC conduction. The DC leakage current (I) in the three types of devices is dominated by Poole–Frenkel (PF) emission and trap-assisted tunneling, before the depletion of the topmost channel and after the depletion of the bottommost channel, respectively. The I in multi-channel devices is dominated by two-dimensional variable range hopping of electrons along the vertical direction between channels, when the topmost channel is depleted while the bottommost channel is not. The analysis is supported by excellent agreement between experimental results and theoretical models, along with activation energies (EA) quantitatively and statistically determined, presenting a promising technology with key understandings for future performance enhancement. [ABSTRACT FROM AUTHOR]

Simple Summary: Simple Summary: Sheep breeding has important economic value in China's animal husbandry industry, and growth traits represent an important factor affecting the economic benefits of the industry. This study is based on a functional 168 bp SINE element insertion upstream of the HOXB13 gene discovered in GWAS. By using whole-genome sequencing (WGS) data, we analyzed the frequency of the HOXB13 gene in 33 different sheep breeds worldwide, and we genotyped 6 specific sheep breeds by using PCR and agarose gel electrophoresis. We also associated the polymorphism of the HOXB13 gene with the growth traits of Luxi black-headed sheep and found that the 168 bp insertion showed a certain correlation with the growth traits in sheep. This may provide effective assistance for improving the economic benefits of the sheep industry. In recent years, genome-wide association studies (GWAS) have uncovered that the HOXB13 gene is a key regulatory factor for the tail length trait of sheep. Further research has found that there is a functional 168 bp SINE element insertion upstream of the HOXB13 gene, which leads to the occurrence of long tails in sheep. However, the frequency of mutations in the 168 bp SINE element of the HOXB13 gene among different sheep breeds around the world and its relationship with growth traits are still unclear. This study used whole-genome sequencing (WGS) data, including 588 samples from 33 different sheep breeds around the world, to evaluate the frequency of HOXB13 gene mutations in different sheep breeds globally. At the same time, this study also selected 3392 sheep samples from six breeds. The genetic variation in the 168 bp InDel locus in the HOXB13 gene was determined through genotyping, and its association with the growth traits of Luxi black-headed sheep was analyzed. The research results indicate that the polymorphism of the 168 bp InDel locus is significantly correlated with the hip width of adult ewes in the Luxi black-headed sheep breed (p < 0.05) and that the hip width of adult ewes with the DD genotype is significantly larger than that of adult ewes with the ID genotype (p < 0.05). This study indicates that there is consistency between the research results on the sheep tail length trait and growth traits, which may contribute to the promotion of sheep breed improvement. [ABSTRACT FROM AUTHOR]

Cyprinus acutidorsalis (Wang, 1979) is an endemic fish in China that is sparsely distributed in the Hainan provinces and Guangxi Zhuang Autonomous Region (GZAR). In this study, the complete mitochondrial genome of C. acutidorsalis from the Hainan population from the Wanquan River was sequenced, and its phylogenetic relationship was analyzed. The circular mtDNA was 16,581 bp in length, and the overall base composition was A (32.0%), C (27.5%), T (24.8%), and G (15.70%), with a slight bias toward A + T. The complete mitogenome encoded 13 protein-coding genes (PCGs), 22 tRNA genes, two rRNA genes, and a control region. Phylogenetic analysis indicated that the most closely related fish to C. acutidorsalis from the Hainan population was C. acutidorsalis from the Guangxi population. These findings offer basic molecular data and a better understanding of the phylogenetic relationships among the Cyprinus species. [ABSTRACT FROM AUTHOR]