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Your search keyword '"Zhang, Kui"' showing total 303 results
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303 results on '"Zhang, Kui"'

1. Hierarchical Consensus-Based Multi-Agent Reinforcement Learning for Multi-Robot Cooperation Tasks

Author

Feng, Pu, Liang, Junkang, Wang, Size, Yu, Xin, Ji, Xin, Chen, Yiting, Zhang, Kui, Shi, Rongye, and Wu, Wenjun

Subjects
Computer Science - Artificial Intelligence, Computer Science - Multiagent Systems, Computer Science - Robotics
Abstract

In multi-agent reinforcement learning (MARL), the Centralized Training with Decentralized Execution (CTDE) framework is pivotal but struggles due to a gap: global state guidance in training versus reliance on local observations in execution, lacking global signals. Inspired by human societal consensus mechanisms, we introduce the Hierarchical Consensus-based Multi-Agent Reinforcement Learning (HC-MARL) framework to address this limitation. HC-MARL employs contrastive learning to foster a global consensus among agents, enabling cooperative behavior without direct communication. This approach enables agents to form a global consensus from local observations, using it as an additional piece of information to guide collaborative actions during execution. To cater to the dynamic requirements of various tasks, consensus is divided into multiple layers, encompassing both short-term and long-term considerations. Short-term observations prompt the creation of an immediate, low-layer consensus, while long-term observations contribute to the formation of a strategic, high-layer consensus. This process is further refined through an adaptive attention mechanism that dynamically adjusts the influence of each consensus layer. This mechanism optimizes the balance between immediate reactions and strategic planning, tailoring it to the specific demands of the task at hand. Extensive experiments and real-world applications in multi-robot systems showcase our framework's superior performance, marking significant advancements over baselines., Comment: 8 pages, 10 figures. Accepted for presentation at the IEEE/RSJ International Conference on Intelligent Robots and Systems (IROS 2024)

Published
2024

12. Using Graph Neural Network to Analyse and Detect Annotation Misuse in Java Code

Author

Yang, Jingbo, Ji, Xin, Wu, Wenjun, Ren, Jian, Zhang, Kui, Zhang, Wenya, Wang, Qingliang, Dong, Tingting, Goos, Gerhard, Series Editor, Hartmanis, Juris, Founding Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Yung, Moti, Editorial Board Member, Huang, De-Shuang, editor, Zhang, Xiankun, editor, and Zhang, Qinhu, editor

Published
2024
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13. Simulation Technology of Unmanned Surface Vehicle Cluster Based on Digital Modeling

Author

Xu, Fengchi, Zhang, Kui, Song, Shengnan, Xie, Yangliu, Angrisani, Leopoldo, Series Editor, Arteaga, Marco, Series Editor, Chakraborty, Samarjit, Series Editor, Chen, Jiming, Series Editor, Chen, Shanben, Series Editor, Chen, Tan Kay, Series Editor, Dillmann, Rüdiger, Series Editor, Duan, Haibin, Series Editor, Ferrari, Gianluigi, Series Editor, Ferre, Manuel, Series Editor, Jabbari, Faryar, Series Editor, Jia, Limin, Series Editor, Kacprzyk, Janusz, Series Editor, Khamis, Alaa, Series Editor, Kroeger, Torsten, Series Editor, Li, Yong, Series Editor, Liang, Qilian, Series Editor, Martín, Ferran, Series Editor, Ming, Tan Cher, Series Editor, Minker, Wolfgang, Series Editor, Misra, Pradeep, Series Editor, Mukhopadhyay, Subhas, Series Editor, Ning, Cun-Zheng, Series Editor, Nishida, Toyoaki, Series Editor, Oneto, Luca, Series Editor, Panigrahi, Bijaya Ketan, Series Editor, Pascucci, Federica, Series Editor, Qin, Yong, Series Editor, Seng, Gan Woon, Series Editor, Speidel, Joachim, Series Editor, Veiga, Germano, Series Editor, Wu, Haitao, Series Editor, Zamboni, Walter, Series Editor, Tan, Kay Chen, Series Editor, Qu, Yi, editor, Gu, Mancang, editor, Niu, Yifeng, editor, and Fu, Wenxing, editor

Published
2024
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16. Tetramethylpyrazine alleviates hypoxia-induced proliferation, migration, and inflammatory response of fibroblast-like synoviocytes via inhibiting the HIF-1α- circCDC42BPB pathway

Author

Yu-jing Zhang, Li-feng Chen, Xu Li, Jian-hua Chen, and Zhang-kui Tan

Subjects
circCDC42BPB, HIF-1α, RA-FLSs, Hypoxia, Diseases of the musculoskeletal system, RC925-935, Immunologic diseases. Allergy, RC581-607
Abstract

Abstract Objectives Rheumatoid arthritis (RA) is a chronic inflammatory joint disease, which might trigger cartilage, bone damage, and disability. Recent studies have suggested that Tetramethylpyrazine (TMP), an alkaloid monomer isolated from the rhizome of the traditional herbal medicine Ligusticum wallichii Franch, exerts a broad spectrum of pharmacological properties, containing anti-inflammatory. This study aimed to analyze the role and underlying mechanism of TMP in RA. Methods Under Hypoxia condition, RA-Fibroblast-like synoviocyte (FLS) were treated with TMP at different doses. Cell viability, proliferation, cell cycle progression, and migration were detected using Cell Counting Kit-8 (CCK-8) assay, 5-ethynyl-2’-deoxyuridine (EdU) assay, flow cytometry assay, wound healing assay, and transwell assay. Cyclin D1, Proliferating cell nuclear antigen (PCNA), Matrix metalloproteinase-2 (MMP2), MMP9, and hypoxia-inducible factor-1α (HIF-1α) protein levels were measured using western blot assay. Interleukin-6 (IL-6) and IL-8 were evaluated using ELISA. Circular RNA (circRNA) hsa_circ_0005178 (circCDC42BPB), CDC42BPB, and HIF-1α expression were determined using real-time quantitative polymerase chain reaction (RT-qPCR). Binding between HIF-1α and CDC42BPB promoter was predicted by JASPAR and verified using dual-luciferase reporter and Chromatin immunoprecipitation (ChIP) assays. Results TMP might hinder FLS proliferation, cycle progression, migration, and inflammatory response under hypoxic conditions. CircCDC42BPB expression was increased in RA patients and RA-FLSs treated with hypoxia, while its level was obviously reduced in RA-FLSs treated with hypoxia and TMP. TMP might abolish hypoxia-induced circCDC42BPB expression. Upregulation of circCDC42BPB might partially overturn the repression of TMP on hypoxia-caused RA-FLS damage. TMP might regulate circCDC42BPB level via HIF-1α in RA-FLSs under hypoxic conditions. Conclusion TMP might block RA-FLS injury partly via regulating the HIF-1α- circCDC42BPB pathway, providing a promising therapeutic target for RA.

Published
2024
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36. Prognostic factors of surgical management for heart failure patients with reduced left ventricular ejection fraction

Author

Mahmoud Yousef Ibrahim Abuharb, Liu Kaiwen, Huang Zhuhui, Zhang Kui, Zheng Jubing, Song Yue, Li Yang, Liu Taoshuai, and Dong Ran

Subjects
Heart failure, LVEF, Retrospective, OPCAB, ONCAB, Heart function, Science (General), Q1-390, Social sciences (General), H1-99
Abstract

Objectives: There are many available pharmaceutical and surgical management for Coronary artery disease (CAD) patients. However, coronary artery bypass grafting (CABG) is the preferred treatment modality for CAD patients with low ejection fraction (EF) in view of the more favorable outcomes. This study aimed to determine the associated factors of poor outcomes post-CABG for heart failure patients with reduced left ventricular ejection fraction who underwent on-pump and off-pump CABG. Methods: A retrospective review of CAD patients who underwent isolated on-pump CABG (ONCAB) or off-pump CABG (OPCAB) in Beijing Anzhen Hospital Affiliated with Capital Medical University from January 2013 to March 2021. Only those with confirmed reduced left ventricular ejection fraction (LVEF) ≤40% on preoperative echocardiography were included. By analyzing the clinical and surgical data, postoperative mortality and morbidity, as well as major cardiovascular and cerebrovascular adverse events (MACCE) as endpoints, certain risk factors of the postoperative complications were identified. Results: Out of the 500 patients, 64 developed MACCE, of which 14 (13.6%) occurred in the ONCAB group and 50 (14.0%) in the OPCAB group. Univariate COX regression analysis showed that age ≥65 years, history of diabetes, and preoperative renal insufficiency were independent risk factors for postoperative primary endpoint events in CAD patients with heart failure with reduced ejection fraction (HFrEF). Following the multivariate COX regression analysis, in addition to the above three risk factors, a history of previous percutaneous coronary angiography (PCI) intervention was also a risk factor for the occurrence of the primary endpoints post-CABG. Conclusion: Based on the analysis, significant predictors of post-CABG MACCE in patients with HFrEF included being older than 65 years old, having diabetes, preoperative renal insufficiency, and having previous PCI.

Published
2024
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50. Oral VV116 versus placebo in patients with mild-to-moderate COVID-19 in China: a multicentre, double-blind, phase 3, randomised controlled study

Author

Fan, Xiaohong, Dai, Xiahong, Ling, Yun, Wu, Lihua, Tang, Lingling, Peng, Chunxian, Huang, Chaolin, Liu, Hongyan, Lu, Hongzhou, Shen, Xinghua, Zhang, Wei, Wang, Furong, Li, Guangming, Li, Ming, Huang, Yanming, Zhang, Hongying, Li, Minghui, Ren, Fei, Li, Yuanyuan, Liu, Chenfan, Zhou, Zhiguo, Sun, Wei, Yi, Yongxiang, Zhou, Daming, Gao, Hainv, Pan, Qi, Liu, Hongde, Zhao, Jiang, Ding, Zhen, Ma, Yingmin, Li, Wei, Wang, Quanhong, Wang, Xicheng, Bai, Yichun, Jiang, Xiangao, Ma, Juan, Xie, Bingying, Zhang, Kui, and Li, Lanjuan

Published
2024
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