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Climate change has directly impacted coffee‐producing regions in Africa. This study uses the two stage Dynamic Network Directional Distance Function (DN‐DDF) and Malmquist Productivity Index (MPI) methods to evaluate the efficiency and productivity changes of agricultural production and sustainable development in 19 African coffee‐producing countries from 2014 to 2018. According to the empirical results, Central African Republic, Ethiopia, Liberia, Uganda, and Zambia have the highest overall efficiency. This study has three main contributions: (1) using a two‐stage model to evaluate the impact of agricultural production efficiency on sustainable development efficiency, (2) using a dynamic model with forest area as a cross‐period variable to reflect the real‐world phenomenon of coffee relying on forest mixed planting, and (3) objectively evaluating the impact of extreme weather on agricultural production by using rainfall as an exogenous variable to address previous research shortcomings. The results of this study can promote the improvement of agricultural production efficiency in African coffee‐producing countries and provide important reference value for sustainable development goals. [ABSTRACT FROM AUTHOR]

Objective: This study investigates the associations of α1-antitrypsin, inter-α-trypsin inhibitor heavy chain (ITIH4), and 8-isoprostane with lung function in shipyard workers exposed to occupational metal fume fine particulate matter (PM2.5), which is known to be associated with adverse respiratory outcomes. Methods: A 3-year follow-up study was conducted on 180 shipyard workers with 262 measurements. Personal exposure to welding fume PM2.5 was collected for an 8-h working day. Pre-exposure, post-exposure, and delta (∆) levels of α1-antitrypsin, ITIH4, and 8-isoprostane were determined in urine using enzyme-linked immunosorbent assays. Post-exposure urinary metals were sampled at the beginning of the next working day and analyzed by inductively coupled plasma-mass spectrometry. Lung function measurements were also conducted the next working day for post-exposure. Results: An IQR increase in PM2.5 was associated with decreases of 2.157% in FEV1, 2.806% in PEF, 4.328% in FEF25%, 5.047% in FEF50%, and 7.205% in FEF75%. An IQR increase in PM2.5 led to increases of 42.155 µg/g in ∆α1-antitrypsin and 16.273 µg/g in ∆ITIH4. Notably, IQR increases in various urinary metals were associated with increases in specific biomarkers, such as post-urinary α1-antitrypsin and ITIH4. Moreover, increases in ∆ α1-antitrypsin and ∆ITIH4 were associated with decreases in FEV1/FVC by 0.008% and 0.020%, respectively, and an increase in ∆8-isoprostane resulted in a 1.538% decline in FVC. Conclusion: Our study suggests that urinary α1-antitrypsin and ITIH4 could indicate early lung function decline in shipyard workers exposed to metal fume PM2.5, underscoring the need for better safety and health monitoring to reduce respiratory risks. [ABSTRACT FROM AUTHOR]