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Anthocyanins have been reported for the protective effects against type 2 diabetes and related obesity. This meta-analysis examined the benefits of anthocyanins on type 2 diabetes and obesity biomarkers in animals and humans. The study included 21 clinical trials and 27 pre-clinical studies. A systematic search was conducted using the following inclusion criteria: in vivo rodent studies; human randomized clinical trials, both aimed at assessing the fasting blood glucose (FBG), HbA1c, total cholesterol, triglycerides, high-density lipoprotein and low-density lipoprotein; and study duration of at least two weeks. Out of the 201 examined publications, 48 were shortlisted after implementation of the selection criteria. Results of clinical trials demonstrated that consumption of anthocyanin-rich food significantly reduced the FBG (p < 0.0001), HbA1c (p = 0.02), TC (p = 0.010), TG (p = 0.003), LDL (p = 0.05) and increases the HDL (p = 0.03) levels. Similarly, pre-clinical studies demonstrated the amelioration of the HbA1c (p = 0.02), FBG, TC, TG, and LDL (p < 0.00001), with non-significant changes in the HDL (p = 0.11). Sub-group analysis indicated dose-dependent effect. This compilation confirms that consuming anthocyanin-rich foods positively correlates with the reduction in the blood glucose and lipid levels in diabetic and obese subjects. [ABSTRACT FROM AUTHOR]

Celiac disease is a chronic autoimmune gastrointestinal condition with a global spread of 0.5 to 1%. It is characterized by inflammation of the small intestine triggered by the consumptionof a protein called gluten found in wheat, rye, and barley. Exposure to gluten results in enteropathy, causing damage to the mucosal surface and leading to nutrient malabsorption. Elimination of gluten from the diet is the only effective way to treat celiac disease. Stress, a ubiquitous condition, both the physical and psychological wellness of an individual is affected by stress. An adaptive reaction especially in the gastrointestinal tract and immune system is produced in response to stress, to ensure the survival of an individual. Upon diagnosis and transition to a gluten-free healthier lifestyle, people suffering from celiac disease often experience heightened levels of emotional imbalance and stigmatization. Addressing these aspects is crucial for both medical and psychological communities. This review aims to explore the association between celiac disease and stress, examining how stress influences the physical and psychosocial life of individuals with this condition. Drawing on numerous reputable papers from diverse authors worldwide, the findings suggest a robust link between celiac disease and stress, leading to anxiety, depression, and stigmatization, directly impacting the standard of living for affected individuals. This article will also explore coping strategies for those dealing with both celiac disease and stress. [ABSTRACT FROM AUTHOR]

In this work, poly(vinylidene fluoride‐hexafluoropropylene) (PVDF‐HFP)/mesoporous graphitic carbon nitride (mpg‐C3N4) composite fiber web have been prepared and characterized for photocatalytic methylene blue (MB) degradation and sensing applications. The electrospinning technique, operating at a flow rate of 1 mL/h and a voltage of 15 kV, was utilized to prepare the composite membranes of PVDF‐HFP with the uniform distribution of the mpg‐C3N4. The composite web demonstrated outstanding photocatalytic activity for the degradation of MB, reaching a quick 68% drop in MB concentration in just 45 min. The composite web furthermore worked as a sensor for MB detection. After MB exposure, the film resistance was increased, suggesting its potential as a chemiresistive sensor. The maximum resistivity of PVDF‐HFP/mpg‐C3N4 composites was found to be 90 Ω·m at 2% concentration of MB. The MB molecules' adsorption on the surface of the composite web and the existence of photocatalytic byproducts on the surface may be responsible for this shift in resistance. This dual functionality highlights the adaptability and potential of the PVDF‐HFP/mpg‐C3N4 composite web as a versatile material for environmental sensing and cleanup. This research presents a comprehensive approach to the synthesis, characterization, and evaluation of such flexible membranes for potential applications as self‐cleaning devices and chemiresistive sensor. Highlights: PVDF‐HFP/mpg‐C3N4 composite membranes act as an efficient material for MB degradation (68%) with visible light exposure.mpg‐C3N4 plays the role of active material in degradation.PVDF‐HFP/mpg‐C3N4 composite membrane also act as sensors for MB detection.Composite membrane becomes chemiresistive due to notable resistivity changes with MB concentration. [ABSTRACT FROM AUTHOR]