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PANoptosis is a novelly defined mode of programmed cell death that involves the activation of multiple cellular death pathways, including pyroptosis, apoptosis, and necroptosis, triggering robust inflammatory reactions. Autophagy is a crucial cellular process that maintains cellular homeostasis and protects cells from various stresses. PANoptosis and autophagy, both vital players in the intricate pathological progression of ischemic stroke (IS), a brain ailment governed by intricate cell death cascades, have garnered attention in recent years for their potential interplay. While mounting evidence hints at a crosstalk between these two processes in IS, the underlying mechanisms remain elusive. Therefore, this review delves into and dissects the intricate mechanisms that underpin the intersection of PANoptosis and autophagy in this devastating condition. In conclusion, the crosstalk between PANoptosis and autophagy in IS presents a promising target for the development of novel stroke therapies. Understanding the interplay between these two pathways offers a much-needed insight into the underlying mechanisms of IS and opens the possibility for new therapeutic strategies. [ABSTRACT FROM AUTHOR]

Conventional methodologies often struggle in accurately positioning underwater habitats and elucidating the complex interactions between terrestrial and aquatic environments. This study proposes an innovative methodology to bridge the gap between these domains, enabling integrated 3D mapping and underwater positioning. The method integrates UAV (Uncrewed Aerial Vehicles) photogrammetry for terrestrial areas with underwater photogrammetry performed by a snorkeler. The innovative aspect of the proposed approach relies on detecting the snorkeler positions on orthorectified images as an alternative to the use of GNSS (Global Navigation Satellite System) positioning, thanks to an image processing tool. Underwater camera positions are estimated through precise time synchronization with the UAV frames, producing a georeferenced 3D model that seamlessly joins terrestrial and submerged landscapes. This facilitates the understanding of the spatial context of objects on the seabed and presents a cost-effective and comprehensive tool for 3D coastal mapping, useful for coastal management to support coastal resilience. [ABSTRACT FROM AUTHOR]

The growing demand for sustainable materials has driven the exploration of natural fibers as eco-friendly alternatives to synthetic reinforcements for composites. This study investigates the potential of Posidonia oceanica, an abundant marine biomass, which is often driven to be stacked on the backshore and used so far for energy recovery and low-value applications, as a filler and possible reinforcement in cementitious and polymer composites. Most applications of Posidonia are concentrated in the Mediterranean area and focused on the construction industry. However, its introduction in polymer composites, especially as a source of cellulose or in combination with the use of bio-based matrices, can also be proposed. With this aim, the physical and chemical properties of Posidonia oceanica fibers need to be characterized, and their compatibility with various matrices needs to be evaluated. Experimental results demonstrate that Posidonia oceanica fibers, especially when treated with alkali and silane, or combining both treatments, can exhibit mechanical properties quite comparable to other natural fibers, namely to those obtained from grass species. As with any other type of waste, yet with more interest for its wide accumulation over the coastal line, the use of Posidonia oceanica in composites may contribute to reducing the environmental footprint of these materials, aligning with circular economy principles. This review highlights the dual benefits of utilizing marine biomass by advancing material sustainability while not being detrimental to coastal waste management. [ABSTRACT FROM AUTHOR]

This mini-review is intended to explore the innovative applications of nanoparticles (NPs) in biogas upgrading, emphasizing their capacity to enhance biogas quality. Numerous studies underscore how NPs, when applied during anaerobic digestion, can boost not only the quantity but also the quality of the produced biogas, leading to reduce significantly the concentration of hydrogen sulphide or even to remove it completely. Moreover, NPs are proving to be excellent alternatives as adsorbent materials, achieving up to 400 mgH2S g−1 NPs. In addition, new studies are exploring the application of NPs to increase the efficiency of biological treatments thanks to their unique features. This review also emphasizes the potential benefits and addresses the challenges that need to be overcome for these technologies to reach their full potential, ultimately contributing to the development of a sustainable and environmentally friendly energy landscape. [ABSTRACT FROM AUTHOR]

Managing fracture infections is a significant challenge in trauma orthopedics, given the limited self-healing capacity of fractures and the difficulty in eradicating infections. In this study, Cu 2 MoS 4 nanoparticles (CMSs) with are prepared enzyme-like activity and both pH and near-infrared (NIR) light responsiveness. These CMSs are combined with methacrylated gelatin (GelMA) to synthesize CMSs hydrogels (CMSs@Gel) with antimicrobial and bone tissue repair-promoting capabilities. In vitro and in vivo experiments, the CMSs@Gel demonstrated good biocompatibility; peroxidase-like (POD), oxidase-like (OXD), and catalase-like (CAT) activities; excellent photothermal conversion efficiency; and immunomodulatory capacity. Furthermore, the CMSs@Gel exhibited slow degradation, enabling it to exert different pH-responsive enzyme activities and modulate the production of reactive oxygen species (ROS) and the polarization of macrophages throughout the treatment process. Notably, these effects are significantly enhanced under near-infrared (NIR) light. Additionally, under NIR irradiation, the CMSs@Gel maintained the fracture environment at a mild temperature (40-42 °C), promoting osteogenesis and angiogenesis. In summary, the CMSs@Gel enhances bactericidal activity during fracture infection and effectively promotes fracture healing after infection control, providing long-term therapeutic effects. This study offers a robust theoretical basis for the staged and long-term treatment of fracture infections in the future., (© 2024 Wiley‐VCH GmbH.)