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1. A PLK1 inhibitor, RO3280, suppresses proliferation of SNU-16 gastric cancer cells via apoptosis

Author

Fatih Yulak and Zekeriya Keskin

Subjects
Anti-cancer, Apoptosis, DNA demage, PLK1 inhibition, RO3280, XTT assay, Therapeutics. Pharmacology, RM1-950
Abstract

This study examines the anti-tumor, pro-apoptotic, and genotoxic effects of polo-like kinase 1 (PLK1) inhibitor RO3280 on the gastric cancer cell line SNU-16. Using the XTT assay, the antiproliferative effect of the compound was identified and showed a significant antiproliferative effect (p

Published
2024
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