Search

A recent study conducted at the University of Texas Arlington examined the relationship between sympathetic and blood pressure reactivity to stress in young adults with major depressive disorder (MDD). The researchers hypothesized that individuals with MDD would exhibit exaggerated reactivity compared to non-depressed individuals. However, the study found no significant differences in reactivity between the two groups. The researchers did find that greater symptom severity in individuals with MDD was associated with increased blood pressure reactivity, potentially increasing the risk of cardiovascular disease. This study provides insight into the physiological responses to stress in individuals with MDD. [Extracted from the article]

A study conducted by researchers at the University of Texas Southwestern Medical Center has identified the mechanisms of a peripherally limited exercise phenotype in patients with heart failure with preserved ejection fraction. The study involved 45 patients who completed cardiopulmonary exercise testing and were categorized as having either a peripheral or central limitation to exercise. The researchers found that peripherally limited patients had impairments in oxygen transport and utilization at the level of skeletal muscle, including increased blood flow/VO2 ratio and poor muscle diffusive capacity. This research provides valuable insights into the understanding of heart failure and its effects on exercise capacity. [Extracted from the article]

Researchers from the University of Auckland in New Zealand have conducted a study on the respiratory modulation of sympathetic transduction to blood pressure in individuals with type 2 diabetes (T2D). The study found that individuals with T2D had impaired respiratory modulation of muscle sympathetic nerve activity (MSNA) and sympathetic transduction to blood pressure, which may contribute to their increased hypertension and cardiovascular risk. The findings suggest that appropriate respiratory-sympathetic coupling is important for blood pressure control in individuals with T2D. This research was supported by the Green Lane Research and Educational Fund and the NIH National Heart Lung & Blood Institute. [Extracted from the article]

A recent study conducted by the University of North Texas explores the relationship between race, sex, and hypertension. The research highlights that non-Hispanic black individuals have the highest prevalence of hypertension compared to other racial/ethnic groups. The study focuses on the role of the sympathetic nervous system in regulating cardiovascular function and suggests that there may be altered sympathetic function in black individuals, particularly in men. The findings have implications for understanding racial disparities in hypertension and cardiovascular disease risk. Further research is needed to fully understand these differences. [Extracted from the article]

A recent study conducted at Texas Health Presbyterian Hospital in Dallas examined the sympathetic neural control in patients with heart failure with preserved ejection fraction (HFpEF). The researchers hypothesized that patients with HFpEF would have higher muscle sympathetic nerve activity (MSNA) at rest and during a cold pressor test compared to non-heart failure controls. The study found that patients with HFpEF did indeed have higher resting MSNA burst frequency and lower sympathetic baroreflex sensitivity compared to controls. However, during the cold pressor test, sympathetic reactivity was intact but diastolic blood pressure responses were attenuated in patients with HFpEF. These findings suggest that the peripheral pathway for sympathetic vasoconstriction may be impaired in HFpEF. The study was supported by the National Institutes of Health (NIH) in the United States. [Extracted from the article]

A recent study conducted at the University of Texas Arlington explored the relationship between major depressive disorder (MDD) and cardiovascular dysfunction. The researchers focused on the role of interleukin-6 (IL-6), a proinflammatory cytokine, in impairing nitric oxide (NO) production and increasing mitochondrial reactive oxygen species (mitoROS) in human aortic endothelial cells. The results indicated that IL-6 treatment significantly reduced NO production and increased mitoROS levels in the cells. These findings suggest that IL-6 may contribute to cardiovascular dysfunction in individuals with MDD. The study was supported by grants from NIH and AHA. [Extracted from the article]

A recent study conducted by Southern Methodist University examined the beat-to-beat blood pressure variability in females with relapsing-remitting multiple sclerosis (RRMS). The researchers found that females with RRMS had reduced blood pressure variability compared to healthy controls. However, this reduction was not related to changes in sympathetic or cardiac baroreflex sensitivity. These findings contribute to our understanding of cardiovascular autonomic dysfunction in individuals with RRMS. [Extracted from the article]

A recent study conducted at the University of Texas Arlington examined the cardiac autonomic function in young adults with major depressive disorder (MDD). The researchers hypothesized that heart rate variability (HRV) and cardiac baroreflex sensitivity (BRS) would be reduced in young unmedicated adults with MDD compared to healthy non-depressed young adults. However, the study found no significant differences in HRV or cardiac BRS between the two groups. The researchers concluded that cardiac autonomic dysfunction may not contribute to elevated cardiovascular risk factor profiles in young unmedicated adults with MDD of mild-to-moderate severity. [Extracted from the article]

2024 JUN 29 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- New research on Heart Disorders and Diseases - Heart Failure is the [...]