1. [Association of illicit drug use in pregnant women and congenital syphilis in a public hospital in Mexico].
- Author
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Miramontes-Buiza L, Lona-Reyes JC, Pérez-Ramírez RO, Magallón-Picazo D, Cordero-Zamora A, Gómez-Ruiz LM, and Cruz-Chávez TA
- Subjects
- Infant, Newborn, Pregnancy, Female, Humans, Infant, Pregnant Women, Case-Control Studies, Mexico epidemiology, Hospitals, Public, Syphilis, Congenital epidemiology, Syphilis, Congenital diagnosis, Syphilis, Congenital etiology, Pregnancy Complications, Infectious epidemiology, Illicit Drugs
- Abstract
We conducted a nested case-control study within a cohort with the aim of studying the association between illicit drug use and congenital syphilis (CS). Cases were diagnosed based on treponemal and non-treponemal tests conducted both in the mother and the newborn (NB). Multivariate analysis with logistic regression was performed. A total of 6171 births with a mean gestational age of 37.8 weeks were recorded and 62 CS events were diagnosed (incidence 10.5 events/1000 NB). Associated maternal factors were illicit drug use (OR 14.08, 95% CI 1.19-166.6), <5 prenatal visits (OR 2.9, 95% CI 1.12-7.53), more than two sexual partners (OR 3.76, 95% CI 1.62-8.71) and professional education level (OR 0.06, 95% CI 0.005-0.85). Among the mothers of the cases presented, the prevalence of illicit drug use was 22.6% and the most frequent drugs were methamphetamines and cannabis., (Copyright © 2023 Asociación Argentina de Microbiología. Publicado por Elsevier España, S.L.U. All rights reserved.)
- Published
- 2024
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