1. Acrodermatitis dysmetabolica: lessons from two pediatric cases.
- Author
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Kahraman AB, Cosar MS, Dogan EE, Ünlü Y, Ugur C, and Bagcı Z
- Abstract
Objectives: Acrodermatitis dysmetabolica (AD) is a dermatologic manifestation associated with inherited metabolic disorders (IMDs), distinct from acrodermatitis enteropathica, which occurs solely due to zinc deficiency., Case Presentation: This report presents two pediatric cases: a 30-month-old girl with maple syrup urine disease (MSUD) experiencing AD secondary to severe isoleucine deficiency due to a protein-restricted diet, showing improvement with dietary adjustments, and a 2.5-month-old boy infant with propionic acidemia (PA) who developed AD alongside septic shock, which progressed despite intervention., Conclusions: These cases emphasize the importance of identifying AD in IMDs and the critical need for meticulous monitoring of amino acid levels, as deficiencies may lead to severe complications., (© 2025 Walter de Gruyter GmbH, Berlin/Boston.)
- Published
- 2025
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