46 results on '"Nadkarni, Vinay"'
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2. Epinephrine Dosing Intervals Are Associated With Pediatric In-Hospital Cardiac Arrest Outcomes: A Multicenter Study
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Kienzle, Martha F., Morgan, Ryan W., Reeder, Ron W., Ahmed, Tageldin, Berg, Robert A., Bishop, Robert, Bochkoris, Matthew, Carcillo, Joseph A., Carpenter, Todd C., Cooper, Kellimarie K., Diddle, J. Wesley, Federman, Myke, Fernandez, Richard, Franzon, Deborah, Frazier, Aisha H., Friess, Stuart H., Frizzola, Meg, Graham, Kathryn, Hall, Mark, Horvat, Christopher, Huard, Leanna L., Maa, Tensing, Manga, Arushi, McQuillen, Patrick S., Meert, Kathleen L., Mourani, Peter M., Nadkarni, Vinay M., Naim, Maryam Y., Pollack, Murray M., Sapru, Anil, Schneiter, Carleen, Sharron, Matthew P., Tabbutt, Sarah, Viteri, Shirley, Wolfe, Heather A., Sutton, Robert M., Bell, Michael J., Burns, Candice, Dean, J. Michael, Fink, Ericka L., Hehir, David, Landis, William P., Notterman, Daniel, Palmer, Chella A., Siems, Ashley, Srivastava, Neeraj, Tilford, Bradley, Wessel, David, Yates, Andrew R., and Zuppa, Athena F.
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- 2024
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3. Association of Postarrest Hypotension Burden With Unfavorable Neurologic Outcome After Pediatric Cardiac Arrest
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Liu, Raymond, Majumdar, Tanmay, Gardner, Monique M., Burnett, Ryan, Graham, Kathryn, Beaulieu, Forrest, Sutton, Robert M., Nadkarni, Vinay M., Berg, Robert A., Morgan, Ryan W., Topjian, Alexis A., and Kirschen, Matthew P.
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- 2024
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4. The impact of pediatric post-cardiac arrest care on survival: A multicenter review from the AHA get with the Guidelines®-resuscitation post-cardiac arrest care registry
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Fowler, Jessica C., Morgan, Ryan W., O’Halloran, Amanda, Gardner, Monique M., Appel, Scott, Wolfe, Heather, Kienzle, Martha F., Raymond, Tia T., Scholefield, Barnaby R, Guerguerian, Anne-Marie, Bembea, Melania M., Nadkarni, Vinay, Berg, Robert A., Sutton, Robert, and Topjian, Alexis A.
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- 2024
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5. Association of EEG characteristics with outcomes following pediatric ICU cardiac arrest: A secondary analysis of the ICU-RESUScitation trial
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Mazzio, Emma L., Topjian, Alexis A., Reeder, Ron W., Sutton, Robert M., Morgan, Ryan W., Berg, Robert A., Nadkarni, Vinay M., Wolfe, Heather A., Graham, Kathryn, Naim, Maryam Y., Friess, Stuart H., Abend, Nicholas S., and Press, Craig A.
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- 2024
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6. Association Between Chest Compression Pause Duration and Survival After Pediatric In-Hospital Cardiac Arrest
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Lauridsen, Kasper G., Morgan, Ryan W., Berg, Robert A., Niles, Dana E., Kleinman, Monica E., Zhang, Xuemei, Griffis, Heather, Del Castillo, Jimena, Skellett, Sophie, Lasa, Javier J., Raymond, Tia T., Sutton, Robert M., and Nadkarni, Vinay M.
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- 2024
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7. Cerebral Oximetry During Pediatric In-Hospital Cardiac Arrest: A Multicenter Study of Survival and Neurologic Outcome*
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Raymond, Tia T., Esangbedo, Ivie D., Rajapreyar, Prakadeshwari, Je, Sangmo, Zhang, Xuemei, Griffis, Heather M., Wakeham, Martin K., Petersen, Tara L., Kirschen, Matthew P., Topjian, Alexis A., Lasa, Javier J., Francoeur, Conall I., and Nadkarni, Vinay M.
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- 2024
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8. Evaluating Airway Management in Patients With Trisomy 21 in the PICU and Cardiac ICU: A Retrospective Cohort Study
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Wilsterman, Eric J., Jr, Nellis, Marianne E., Panisello, Josep, Al-Subu, Awni, Breuer, Ryan, Kimura, Dai, Krawiec, Conrad, Mallory, Palen P., Nett, Sholeen, Owen, Erin, Parsons, Simon J., Sanders, Ronald C., Jr, Garcia-Marcinkiewicz, Annery, Napolitano, Natalie, Shults, Justine, Nadkarni, Vinay M., and Nishisaki, Akira
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- 2024
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9. Early Cardiac Arrest Hemodynamics, End-Tidal CO2, and Outcome in Pediatric Extracorporeal Cardiopulmonary Resuscitation: Secondary Analysis of the ICU-RESUScitation Project Dataset (2016–2021)*
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Yates, Andrew R., Naim, Maryam Y., Reeder, Ron W., Ahmed, Tageldin, Banks, Russell K., Bell, Michael J., Berg, Robert A., Bishop, Robert, Bochkoris, Matthew, Burns, Candice, Carcillo, Joseph A., Carpenter, Todd C., Dean, J. Michael, Diddle, J. Wesley, Federman, Myke, Fernandez, Richard, Fink, Ericka L., Franzon, Deborah, Frazier, Aisha H., Friess, Stuart H., Graham, Kathryn, Hall, Mark, Hehir, David A., Horvat, Christopher M., Huard, Leanna L., Maa, Tensing, Manga, Arushi, McQuillen, Patrick S., Morgan, Ryan W., Mourani, Peter M., Nadkarni, Vinay M., Notterman, Daniel, Pollack, Murray M., Sapru, Anil, Schneiter, Carleen, Sharron, Matthew P., Srivastava, Neeraj, Tilford, Bradley, Viteri, Shirley, Wessel, David, Wolfe, Heather A., Yeh, Justin, Zuppa, Athena F., Sutton, Robert M., and Meert, Kathleen L.
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- 2024
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10. The association of recent simulation training and clinical experience of team leaders with cardiopulmonary resuscitation quality during in-hospital cardiac arrest
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Wittig, Johannes, Løfgren, Bo, Nielsen, Rasmus P., Højbjerg, Rikke, Krogh, Kristian, Kirkegaard, Hans, Berg, Robert A., Nadkarni, Vinay M., and Lauridsen, Kasper G.
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- 2024
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11. Association between survival and number of shocks for pulseless ventricular arrhythmias during pediatric in-hospital cardiac arrest in a national registry
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Haskell, Sarah E., Hoyme, Derek, Zimmerman, M. Bridget, Reeder, Ron, Girotra, Saket, Raymond, Tia T., Samson, Ricardo A., Berg, Marc, Berg, Robert A., Nadkarni, Vinay, and Atkins, Dianne L.
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- 2024
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12. 2023 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations: Summary From the Basic Life Support; Advanced Life Support; Pediatric Life Support; Neonatal Life Support; Education, Implementation, and Teams; and First Aid Task Forces
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Barcala-Furelos, Roberto, Beerman, Stephen B., Bruckner, Marlies, Castrén, Maaret, Chong, ShuLing, Claesson, Andreas, Dunne, Cody L., Finan, Emer, Fukuda, Tatsuma, Lalgudi Ganesan, Saptharishi, Gately, Callum, Gois, Aecio, Gray, Seth, Halamek, Louis P., Hoover, Amber V., Hurst, Cameron, Josephsen, Justin, Kollander, Louise, Omar Kamlin, C., Kool, Mirjam, Li, Lei, Mecrow, Thomas S., Montgomery, William, Ristau, Patrick, Jayashree, Muralidharan, Schmidt, Andrew, Scquizzato, Tommaso, Seesink, Jeroen, Sempsrott, Justin, Lee Solevåg, Anne, Strand, Marya L., Szpilman, David, Szyld, Edgardo, Thom, Ogilvie, Tobin, Joshua M., Trang, Jacinta, Webber, Jonathon, Webster, Hannah K., Wellsford, Michelle, Berg, Katherine M., Bray, Janet E., Ng, Kee-Chong, Liley, Helen G., Greif, Robert, Carlson, Jestin N., Morley, Peter T., Drennan, Ian R., Smyth, Michael, Scholefield, Barnaby R., Weiner, Gary M., Cheng, Adam, Djärv, Therese, Abelairas-Gómez, Cristian, Acworth, Jason, Andersen, Lars W., Atkins, Dianne L., Berry, David C., Bhanji, Farhan, Bierens, Joost, Bittencourt Couto, Thomaz, Borra, Vere, Böttiger, Bernd W., Bradley, Richard N., Breckwoldt, Jan, Cassan, Pascal, Chang, Wei-Tien, Charlton, Nathan P., Chung, Sung Phil, Considine, Julie, Costa-Nobre, Daniela T., Couper, Keith, Dainty, Katie N., Dassanayake, Vihara, Davis, Peter G., Dawson, Jennifer A., Fernanda de Almeida, Maria, De Caen, Allan R., Deakin, Charles D., Dicker, Bridget, Douma, Matthew J., Eastwood, Kathryn, El-Naggar, Walid, Fabres, Jorge G., Fawke, Joe, Fijacko, Nino, Finn, Judith C., Flores, Gustavo E., Foglia, Elizabeth E., Folke, Fredrik, Gilfoyle, Elaine, Goolsby, Craig A., Granfeldt, Asger, Guerguerian, Anne-Marie, Guinsburg, Ruth, Hatanaka, Tetsuo, Hirsch, Karen G., Holmberg, Mathias J., Hosono, Shigeharu, Hsieh, Ming-Ju, Hsu, Cindy H., Ikeyama, Takanari, Isayama, Tetsuya, Johnson, Nicholas J., Kapadia, Vishal S., Daripa Kawakami, Mandira, Kim, Han-Suk, Kleinman, Monica E., Kloeck, David A., Kudenchuk, Peter, Kule, Amy, Kurosawa, Hiroshi, Lagina, Anthony T., Lauridsen, Kasper G., Lavonas, Eric J., Lee, Henry C., Lin, Yiqun, Lockey, Andrew S., Macneil, Finlay, Maconochie, Ian K., John Madar, R., Malta Hansen, Carolina, Masterson, Siobhan, Matsuyama, Tasuku, McKinlay, Christopher J.D., Meyran, Daniel, Monnelly, Vix, Nadkarni, Vinay, Nakwa, Firdose L., Nation, Kevin J., Nehme, Ziad, Nemeth, Michael, Neumar, Robert W., Nicholson, Tonia, Nikolaou, Nikolaos, Nishiyama, Chika, Norii, Tatsuya, Nuthall, Gabrielle A., Ohshimo, Shinchiro, Olasveengen, Theresa M., Gene Ong, Yong-Kwang, Orkin, Aaron M., Parr, Michael J., Patocka, Catherine, Perkins, Gavin D., Perlman, Jeffrey M., Rabi, Yacov, Raitt, James, Ramachandran, Shalini, Ramaswamy, Viraraghavan V., Raymond, Tia T., Reis, Amelia G., Reynolds, Joshua C., Ristagno, Giuseppe, Rodriguez-Nunez, Antonio, Roehr, Charles C., Rüdiger, Mario, Sakamoto, Tetsuya, Sandroni, Claudio, Sawyer, Taylor L., Schexnayder, Steve M., Schmölzer, Georg M., Schnaubelt, Sebastian, Semeraro, Federico, Singletary, Eunice M., Skrifvars, Markus B., Smith, Christopher M., Soar, Jasmeet, Stassen, Willem, Sugiura, Takahiro, Tijssen, Janice A., Topjian, Alexis A., Trevisanuto, Daniele, Vaillancourt, Christian, Wyckoff, Myra H., Wyllie, Jonathan P., Yang, Chih-Wei, Yeung, Joyce, Zelop, Carolyn M., Zideman, David A., and Nolan, Jerry P.
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- 2024
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13. A research definition and framework for acute paediatric critical illness across resource-variable settings: a modified Delphi consensus
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Arias, Anita V, Lintner-Rivera, Michael, Shafi, Nadeem I, Abbas, Qalab, Abdelhafeez, Abdelhafeez H, Ali, Muhammad, Ammar, Halaashuor, Anwar, Ali I, Adabie Appiah, John, Attebery, Jonah E, Diaz Villalobos, Willmer E, Ferreira, Daiane, González-Dambrauskas, Sebastián, Irfan Habib, Muhammad, Lee, Jan Hau, Kissoon, Niranjan, Tekleab, Atnafu M, Molyneux, Elizabeth M, Morrow, Brenda M, Nadkarni, Vinay M, Rivera, Jocelyn, Silvers, Rebecca, Steere, Mardi, Tatay, Daniel, Bhutta, Adnan T, Kortz, Teresa B, and Agulnik, Asya
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- 2024
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14. Chest compressions for pediatric organized rhythms: A hemodynamic and outcomes analysis
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Zinna, Shairbanu S., Morgan, Ryan W., Reeder, Ron W., Ahmed, Tageldin, Bell, Michael J., Bishop, Robert, Bochkoris, Matthew, Burns, Candice, Carcillo, Joseph A., Carpenter, Todd C., Cooper, Kellimarie K., Michael Dean, J., Wesley Diddle, J., Federman, Myke, Fernandez, Richard, Fink, Ericka L., Franzon, Deborah, Frazier, Aisha H., Friess, Stuart H., Graham, Kathryn, Hall, Mark, Harding, Monica L., Hehir, David A., Horvat, Christopher M., Huard, Leanna L., Landis, William P., Maa, Tensing, Manga, Arushi, McQuillen, Patrick S., Meert, Kathleen L., Mourani, Peter M, Nadkarni, Vinay M., Naim, Maryam Y., Notterman, Daniel, Pollack, Murray M., Sapru, Anil, Schneiter, Carleen, Sharron, Matthew P., Srivastava, Neeraj, Tilford, Bradley, Viteri, Shirley, Wessel, David, Wolfe, Heather A., Yates, Andrew R., Zuppa, Athena F., Berg, Robert A., and Sutton, Robert M.
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- 2024
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15. Associations Between End-Tidal Carbon Dioxide During Pediatric Cardiopulmonary Resuscitation, Cardiopulmonary Resuscitation Quality, and Survival
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Morgan, Ryan W., Reeder, Ron W., Bender, Dieter, Cooper, Kellimarie K., Friess, Stuart H., Graham, Kathryn, Meert, Kathleen L., Mourani, Peter M., Murray, Robert, Nadkarni, Vinay M., Nataraj, Chandrasekhar, Palmer, Chella A., Srivastava, Neeraj, Tilford, Bradley, Wolfe, Heather A., Yates, Andrew R., Berg, Robert A., Sutton, Robert M., Ahmed, Tageldin, Bell, Michael J., Bishop, Robert, Bochkoris, Matthew, Burns, Candice, Carpenter, Todd C., Carcillo, Joseph A., Dean, J. Michael, Diddle, J. Wesley, Federman, Myke, Fernandez, Richard, Fink, Ericka L, Franzon, Deborah, Frazier, Aisha H., Hall, Mark, Hehir, David A., Horvat, Christopher M., Huard, Leanna L., Maa, Tensing, Manga, Arushi, McQuillen, Patrick S., Naim, Maryam Y., Notterman, Daniel, Pollack, Murray M., Sapru, Anil, Schneiter, Carleen, Sharron, Matthew P., Tabbutt, Sarah, Viteri, Shirley, Wessel, David, and Zuppa, Athena F.
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- 2024
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16. Survival With Favorable Neurologic Outcome and Quality of Cardiopulmonary Resuscitation Following In-Hospital Cardiac Arrest in Children With Cardiac Disease Compared With Noncardiac Disease*
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Federman, Myke, Sutton, Robert M., Reeder, Ron W., Ahmed, Tageldin, Bell, Michael J., Berg, Robert A., Bishop, Robert, Bochkoris, Matthew, Burns, Candice, Carcillo, Joseph A., Carpenter, Todd C., Dean, J. Michael, Diddle, J. Wesley, Fernandez, Richard, Fink, Ericka L., Franzon, Deborah, Frazier, Aisha H., Friess, Stuart H., Graham, Kathryn, Hall, Mark, Hehir, David A., Horvat, Christopher M., Huard, Leanna L., Kirkpatrick, Theresa, Maa, Tensing, Maitoza, Laura A., Manga, Arushi, McQuillen, Patrick S., Meert, Kathleen L., Morgan, Ryan W., Mourani, Peter M., Nadkarni, Vinay M., Notterman, Daniel, Palmer, Chella A., Pollack, Murray M., Sapru, Anil, Schneiter, Carleen, Sharron, Matthew P., Srivastava, Neeraj, Tilford, Bradley, Viteri, Shirley, Wessel, David, Wolfe, Heather A., Yates, Andrew R., Zuppa, Athena F., and Naim, Maryam Y.
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- 2024
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17. 1284: IMPACT OF DIGITIZATION OF PEDIATRIC AIRWAY BUNDLE CHECKLIST ON ADHERENCE AND PROCEDURAL SAFETY
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Gee, Kalli, Schramm, Stephanie, Hozumi, Takunori, Pablo Jaldin, Juan, Kelly, Nancy-Ann, Dominick, Cheryl, Faulkner, Erica, Sannino, James, Fidel, Alexander, Manzi, Amanda, Singaravelu, Anbumalar, Traynor, Danielle, Buffman, Hayley, Napolitano, Natalie, Laverriere McGovern, Elizabeth, Nadkarni, Vinay, Davis, Daniela, and Nishisaki, Akira
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- 2024
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18. 737: USE AND SAFETY OF ETOMIDATE FOR INTUBATION OF CRITICALLY ILL CHILDREN
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Ducharme-Crevier, Laurence, Thibault, Celine, Emeriaud, Guillaume, Napolitano, Natalie, Wing, Robyn, Prieto, Monica, Romer, Amy, Branca, Aline, Shults, Justine, Nadkarni, Vinay, and Nishisaki, Akira
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- 2024
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19. 718: PROGRESSION TO PULSELESSNESS AMONG CHILDREN RECEIVING CPR FOR BRADYCARDIA WITH POOR PERFUSION
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O’Halloran, Amanda, Reeder, Ron, Berg, Robert, Cooper, Kellimarie, Graham, Kathryn, Kienzle, Martha, Kilbaugh, Todd, Meert, Kathleen, Nadkarni, Vinay, Topjian, Alexis, Wolfe, Heather, Yates, Andrew, Sutton, Robert, and Morgan, Ryan
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- 2024
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20. 681: IMPACT OF APNEIC OXYGENATION ON TRACHEAL INTUBATION OUTCOMES IN THE PICU, CICU, AND ED
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Napolitano, Natalie, Harwayne-Gidansky, Ilana, Polikoff, Lee, Sanders, Ronald, Prieto, Monica, Wing, Robyn, Branca, Aline, Romer, Amy, Laverriere McGovern, Elizabeth, Shults, Justine, Nadkarni, Vinay, and Nishisaki, Akira
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- 2024
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21. 41: CAUSES FOR LOW-QUALITY BAG-MASK VENTILATION DIFFER ACROSS PEDIATRIC AGE GROUPS
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Shepard, Lindsay, Napolitano, Natalie, Dominick, Cheryl, Nickel, Amanda, Shults, Justine, Laverriere McGovern, Elizabeth, Bruins, Benjamin, O’Halloran, Amanda, Huh, Jimmy, Topjian, Alexis, Kirschen, Matthew, Morgan, Ryan, Sutton, Robert, Nadkarni, Vinay, and Nishisaki, Akira
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- 2024
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22. 44: LOW QUALITY BAG-MASK VENTILATION IS ASSOCIATED WITH ADVERSE AIRWAY OUTCOMES
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Shepard, Lindsay, Napolitano, Natalie, Dominick, Cheryl, Nickel, Amanda, Shults, Justine, Laverriere McGovern, Elizabeth, Bruins, Benjamin, O’Halloran, Amanda, Huh, Jimmy, Topjian, Alexis, Kirschen, Matthew, Morgan, Ryan, Sutton, Robert, Nadkarni, Vinay, and Nishisaki, Akira
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- 2024
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23. Corrigendum to “2022 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations: Summary From the Basic Life Support; Advanced Life Support; Pediatric Life Support; Neonatal Life Support; Education, Implementation, and Teams; and First Aid Task Forces” [Resuscitation 181 (2022) 208–288]
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Wyckoff, Myra H., primary, Greif, Robert, additional, Morley, Peter T., additional, Ng, Kee-Chong, additional, Olasveengen, Theresa M., additional, Singletary, Eunice M., additional, Soar, Jasmeet, additional, Cheng, Adam, additional, Drennan, Ian R., additional, Liley, Helen G., additional, Scholefield, Barnaby R., additional, Smyth, Michael A., additional, Welsford, Michelle, additional, Zideman, David A., additional, Acworth, Jason, additional, Aickin, Richard, additional, Andersen, Lars W., additional, Atkins, Diane, additional, Berry, David C., additional, Bhanji, Farhan, additional, Bierens, Joost, additional, Borra, Vere, additional, Böttiger, Bernd W., additional, Bradley, Richard N., additional, Bray, Janet E., additional, Breckwoldt, Jan, additional, Callaway, Clifton W., additional, Carlson, Jestin N., additional, Cassan, Pascal, additional, Castrén, Maaret, additional, Chang, Wei-Tien, additional, Charlton, Nathan P., additional, Chung, Sung Phil, additional, Considine, Julie, additional, Costa-Nobre, Daniela T., additional, Couper, Keith, additional, Couto, Thomaz Bittencourt, additional, Dainty, Katie N., additional, Davis, Peter G., additional, de Almeida, Maria Fernanda, additional, de Caen, Allan R., additional, Deakin, Charles D., additional, Djärv, Therese, additional, Donnino, Michael W., additional, Douma, Matthew J., additional, Duff, Jonathan P., additional, Dunne, Cody L., additional, Eastwood, Kathryn, additional, El-Naggar, Walid, additional, Fabres, Jorge G., additional, Fawke, Joe, additional, Finn, Judith, additional, Foglia, Elizabeth E., additional, Folke, Fredrik, additional, Gilfoyle, Elaine, additional, Goolsby, Craig A., additional, Granfeldt, Asger, additional, Guerguerian, Anne-Marie, additional, Guinsburg, Ruth, additional, Hirsch, Karen G., additional, Holmberg, Mathias J., additional, Hosono, Shigeharu, additional, Hsieh, Ming-Ju, additional, Hsu, Cindy H., additional, Ikeyama, Takanari, additional, Isayama, Tetsuya, additional, Johnson, Nicholas J., additional, Kapadia, Vishal S., additional, Daripa Kawakami, Mandira, additional, Kim, Han-Suk, additional, Kleinman, Monica, additional, Kloeck, David A., additional, Kudenchuk, Peter J., additional, Lagina, Anthony T., additional, Lauridsen, Kasper G., additional, Lavonas, Eric J., additional, Lee, Henry C., additional, (Jeffrey) Lin, Yiqun, additional, Lockey, Andrew S., additional, Maconochie, Ian K., additional, John Madar, R., additional, Hansen, Carolina Malta, additional, Masterson, Siobhan, additional, Matsuyama, Tasuku, additional, McKinlay, Christopher J.D., additional, Meyran, Daniel, additional, Morgan, Patrick, additional, Morrison, Laurie J., additional, Nadkarni, Vinay, additional, Nakwa, Firdose L., additional, Nation, Kevin J., additional, Nehme, Ziad, additional, Nemeth, Michael, additional, Neumar, Robert W., additional, Nicholson, Tonia, additional, Nikolaou, Nikolaos, additional, Nishiyama, Chika, additional, Norii, Tatsuya, additional, Nuthall, Gabrielle A., additional, O'Neill, Brian J., additional, Gene Ong, Yong-Kwang, additional, Orkin, Aaron M., additional, Paiva, Edison F., additional, Parr, Michael J., additional, Patocka, Catherine, additional, Pellegrino, Jeffrey L., additional, Perkins, Gavin D., additional, Perlman, Jeffrey M., additional, Rabi, Yacov, additional, Reis, Amelia G., additional, Reynolds, Joshua C., additional, Ristagno, Giuseppe, additional, Rodriguez-Nunez, Antonio, additional, Roehr, Charles C., additional, Rüdiger, Mario, additional, Sakamoto, Tetsuya, additional, Sandroni, Claudio, additional, Sawyer, Taylor L., additional, Schexnayder, Steve M., additional, Schmölzer, Georg M., additional, Schnaubelt, Sebastian, additional, Semeraro, Federico, additional, Skrifvars, Markus B., additional, Smith, Christopher M., additional, Sugiura, Takahiro, additional, Tijssen, Janice A., additional, Trevisanuto, Daniele, additional, Van de Voorde, Patrick, additional, Wang, Tzong-Luen, additional, Weiner, Gary M., additional, Wyllie, Jonathan P., additional, Yang, Chih-Wei, additional, Yeung, Joyce, additional, Nolan, Jerry P., additional, Berg, Katherine M., additional, Burdick, Madeline C., additional, Cartledge, Susie, additional, Dawson, Jennifer A., additional, Elgohary, Moustafa M., additional, Ersdal, Hege L., additional, Finan, Emer, additional, Flaatten, Hilde I., additional, Flores, Gustavo E., additional, Fuerch, Janene, additional, Garg, Rakesh, additional, Gately, Callum, additional, Goh, Mark, additional, Halamek, Louis P., additional, Handley, Anthony J., additional, Hatanaka, Tetsuo, additional, Hoover, Amber, additional, Issa, Mohmoud, additional, Johnson, Samantha, additional, Kamlin, C. Omar, additional, Ko, Ying-Chih, additional, Kule, Amy, additional, Leone, Tina A., additional, MacKenzie, Ella, additional, Macneil, Finlay, additional, Montgomery, William, additional, O'Dochartaigh, Domhnall, additional, Ohshimo, Shinichiro, additional, Palazzo, Francesco Stefano, additional, Picard, Christopher, additional, Quek, Bin Huey, additional, Raitt, James, additional, Ramaswamy, Viraraghavan V., additional, Scapigliati, Andrea, additional, Shah, Birju A., additional, Stewart, Craig, additional, Strand, Marya L., additional, Szyld, Edgardo, additional, Thio, Marta, additional, Topjian, Alexis A., additional, Udaeta, Enrique, additional, Vaillancourt, Christian, additional, Wetsch, Wolfgang A., additional, Wigginton, Jane, additional, Yamada, Nicole K., additional, Yao, Sarah, additional, Zace, Drieda, additional, and Zelop, Carolyn M., additional
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- 2024
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24. ILCOR Pediatric Life Support Recommendations Translation to Constituent Council Guidelines: An Emphasis on Similarities and Differences
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Shepard, Lindsay N., primary, Nadkarni, Vinay M., additional, Ng, Kee-Chong, additional, Scholefield, Barnaby R., additional, and Ong, Gene Y., additional
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- 2024
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25. Correction to: Interventions to promote cost-effectiveness in adult intensive care units: consensus statement and considerations for best practice from a multidisciplinary and multinational eDelphi study
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Kansal, Amit, primary, Latour, Jos M., additional, See, Kay Choong, additional, Rai, Sumeet, additional, Cecconi, Maurizio, additional, Britto, Carl, additional, Conway Morris, Andrew, additional, Dominic Savio, Raymond, additional, Nadkarni, Vinay M., additional, Rao, B. K., additional, and Mishra, Rajesh, additional
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- 2024
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26. Chest Compression Depth Targets in Critically Ill Infants and Children Measured With a Laser Distance Meter: Single-Center Retrospective Study From Japan, 2019–2022
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Ikeyama, Takanari, primary, Hozumi, Takunori, additional, Kikuyama, Kazuki, additional, Niles, Dana, additional, Nadkarni, Vinay, additional, and Ito, Komei, additional
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- 2024
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27. Evaluation of Automated Finger Compression for Capillary Refill Time Measurement in Pediatrics.
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Nickel, Amanda J., Shen Jiang, Napolitano, Natalie, Donoghue, Aaron, Nadkarni, Vinay M., and Akira Nishisaki
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- 2024
28. Factors that impact second attempt success for neonatal intubation following first attempt failure: a report from the National Emergency Airway Registry for Neonates
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Johnson, Mitchell David, primary, Tingay, David Gerald, additional, Perkins, Elizabeth J, additional, Sett, Arun, additional, Devsam, Bianca, additional, Douglas, Ellen, additional, Charlton, Julia K, additional, Wildenhain, Paul, additional, Rumpel, Jennifer, additional, Wagner, Michael, additional, Nadkarni, Vinay, additional, Johnston, Lindsay, additional, Herrick, Heidi M, additional, Hartman, Tyler, additional, Glass, Kristen, additional, Jung, Philipp, additional, DeMeo, Stephen D, additional, Shay, Rebecca, additional, Kim, Jae H, additional, Unrau, Jennifer, additional, Moussa, Ahmed, additional, Nishisaki, Akira, additional, and Foglia, Elizabeth E, additional
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- 2024
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29. 2023 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations: Summary From the Basic Life Support; Advanced Life Support; Pediatric Life Support; Neonatal Life Support; Education, Implementation, and Teams; and First Aid Task Forces
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Berg, Katherine M., primary, Bray, Janet E., additional, Ng, Kee-Chong, additional, Liley, Helen G., additional, Greif, Robert, additional, Carlson, Jestin N., additional, Morley, Peter T., additional, Drennan, Ian R., additional, Smyth, Michael, additional, Scholefield, Barnaby R., additional, Weiner, Gary M., additional, Cheng, Adam, additional, Djärv, Therese, additional, Abelairas-Gómez, Cristian, additional, Acworth, Jason, additional, Andersen, Lars W., additional, Atkins, Dianne L., additional, Berry, David C., additional, Bhanji, Farhan, additional, Bierens, Joost, additional, Bittencourt Couto, Thomaz, additional, Borra, Vere, additional, Böttiger, Bernd W., additional, Bradley, Richard N., additional, Breckwoldt, Jan, additional, Cassan, Pascal, additional, Chang, Wei-Tien, additional, Charlton, Nathan P., additional, Chung, Sung Phil, additional, Considine, Julie, additional, Costa-Nobre, Daniela T., additional, Couper, Keith, additional, Dainty, Katie N., additional, Dassanayake, Vihara, additional, Davis, Peter G., additional, Dawson, Jennifer A., additional, Fernanda de Almeida, Maria, additional, De Caen, Allan R., additional, Deakin, Charles D., additional, Dicker, Bridget, additional, Douma, Matthew J., additional, Eastwood, Kathryn, additional, El-Naggar, Walid, additional, Fabres, Jorge G., additional, Fawke, Joe, additional, Fijacko, Nino, additional, Finn, Judith C., additional, Flores, Gustavo E., additional, Foglia, Elizabeth E., additional, Folke, Fredrik, additional, Gilfoyle, Elaine, additional, Goolsby, Craig A., additional, Granfeldt, Asger, additional, Guerguerian, Anne-Marie, additional, Guinsburg, Ruth, additional, Hatanaka, Tetsuo, additional, Hirsch, Karen G., additional, Holmberg, Mathias J., additional, Hosono, Shigeharu, additional, Hsieh, Ming-Ju, additional, Hsu, Cindy H., additional, Ikeyama, Takanari, additional, Isayama, Tetsuya, additional, Johnson, Nicholas J., additional, Kapadia, Vishal S., additional, Daripa Kawakami, Mandira, additional, Kim, Han-Suk, additional, Kleinman, Monica E., additional, Kloeck, David A., additional, Kudenchuk, Peter, additional, Kule, Amy, additional, Kurosawa, Hiroshi, additional, Lagina, Anthony T., additional, Lauridsen, Kasper G., additional, Lavonas, Eric J., additional, Lee, Henry C., additional, Lin, Yiqun, additional, Lockey, Andrew S., additional, Macneil, Finlay, additional, Maconochie, Ian K., additional, John Madar, R., additional, Malta Hansen, Carolina, additional, Masterson, Siobhan, additional, Matsuyama, Tasuku, additional, McKinlay, Christopher J.D., additional, Meyran, Daniel, additional, Monnelly, Vix, additional, Nadkarni, Vinay, additional, Nakwa, Firdose L., additional, Nation, Kevin J., additional, Nehme, Ziad, additional, Nemeth, Michael, additional, Neumar, Robert W., additional, Nicholson, Tonia, additional, Nikolaou, Nikolaos, additional, Nishiyama, Chika, additional, Norii, Tatsuya, additional, Nuthall, Gabrielle A., additional, Ohshimo, Shinchiro, additional, Olasveengen, Theresa M., additional, Gene Ong, Yong-Kwang, additional, Orkin, Aaron M., additional, Parr, Michael J., additional, Patocka, Catherine, additional, Perkins, Gavin D., additional, Perlman, Jeffrey M., additional, Rabi, Yacov, additional, Raitt, James, additional, Ramachandran, Shalini, additional, Ramaswamy, Viraraghavan V., additional, Raymond, Tia T., additional, Reis, Amelia G., additional, Reynolds, Joshua C., additional, Ristagno, Giuseppe, additional, Rodriguez-Nunez, Antonio, additional, Roehr, Charles C., additional, Rüdiger, Mario, additional, Sakamoto, Tetsuya, additional, Sandroni, Claudio, additional, Sawyer, Taylor L., additional, Schexnayder, Steve M., additional, Schmölzer, Georg M., additional, Schnaubelt, Sebastian, additional, Semeraro, Federico, additional, Singletary, Eunice M., additional, Skrifvars, Markus B., additional, Smith, Christopher M., additional, Soar, Jasmeet, additional, Stassen, Willem, additional, Sugiura, Takahiro, additional, Tijssen, Janice A., additional, Topjian, Alexis A., additional, Trevisanuto, Daniele, additional, Vaillancourt, Christian, additional, Wyckoff, Myra H., additional, Wyllie, Jonathan P., additional, Yang, Chih-Wei, additional, Yeung, Joyce, additional, Zelop, Carolyn M., additional, Zideman, David A., additional, Nolan, Jerry P., additional, Barcala-Furelos, Roberto, additional, Beerman, Stephen B., additional, Bruckner, Marlies, additional, Castrén, Maaret, additional, Chong, ShuLing, additional, Claesson, Andreas, additional, Dunne, Cody L., additional, Finan, Emer, additional, Fukuda, Tatsuma, additional, Lalgudi Ganesan, Saptharishi, additional, Gately, Callum, additional, Gois, Aecio, additional, Gray, Seth, additional, Halamek, Louis P., additional, Hoover, Amber V., additional, Hurst, Cameron, additional, Josephsen, Justin, additional, Kollander, Louise, additional, Omar Kamlin, C., additional, Kool, Mirjam, additional, Li, Lei, additional, Mecrow, Thomas S., additional, Montgomery, William, additional, Ristau, Patrick, additional, Jayashree, Muralidharan, additional, Schmidt, Andrew, additional, Scquizzato, Tommaso, additional, Seesink, Jeroen, additional, Sempsrott, Justin, additional, Lee Solevåg, Anne, additional, Strand, Marya L., additional, Szpilman, David, additional, Szyld, Edgardo, additional, Thom, Ogilvie, additional, Tobin, Joshua M., additional, Trang, Jacinta, additional, Webber, Jonathon, additional, Webster, Hannah K., additional, and Wellsford, Michelle, additional
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- 2024
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30. Association of Pediatric Postcardiac Arrest Ventilation and Oxygenation with Survival Outcomes.
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Frazier, Aisha H., Topjian, Alexis A., Reeder, Ron W., Morgan, Ryan W., Fink, Ericka L., Franzon, Deborah, Graham, Kathryn, Harding, Monica L., Mourani, Peter M., Nadkarni, Vinay M., Wolfe, Heather A., Ahmed, Tageldin, Bell, Michael J., Burns, Candice, Carcillo, Joseph A., Carpenter, Todd C., Diddle, J. Wesley, Federman, Myke, Friess, Stuart H., and Hall, Mark
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SURVIVAL analysis (Biometry) ,SURVIVAL rate ,PREMATURE infants ,CHEST compressions ,OXYGEN in the blood ,INTENSIVE care units ,HOSPITAL admission & discharge - Abstract
Rationale: Adult and pediatric studies provide conflicting data regarding whether post–cardiac arrest hypoxemia, hyperoxemia, hypercapnia, and/or hypocapnia are associated with worse outcomes. Objectives: We sought to determine whether postarrest hypoxemia or postarrest hyperoxemia is associated with lower rates of survival to hospital discharge, compared with postarrest normoxemia, and whether postarrest hypocapnia or hypercapnia is associated with lower rates of survival, compared with postarrest normocapnia. Methods: An embedded prospective observational study during a multicenter interventional cardiopulmonary resuscitation trial was conducted from 2016 to 2021. Patients ⩽18 years old and with a corrected gestational age of ≥37 weeks who received chest compressions for cardiac arrest in one of the 18 intensive care units were included. Exposures during the first 24 hours postarrest were hypoxemia, hyperoxemia, or normoxemia—defined as lowest arterial oxygen tension/pressure (Pa
O ) <60 mm Hg, highest Pa2 O ⩾200 mm Hg, or every Pa2 O 60–199 mm Hg, respectively—and hypocapnia, hypercapnia, or normocapnia, defined as lowest arterial carbon dioxide tension/pressure (Pa2 CO ) <30 mm Hg, highest Pa2 CO ⩾50 mm Hg, or every Pa2 CO 30–49 mm Hg, respectively. Associations of oxygenation and carbon dioxide group with survival to hospital discharge were assessed using Poisson regression with robust error estimates. Results: The hypoxemia group was less likely to survive to hospital discharge, compared with the normoxemia group (adjusted relative risk [aRR] = 0.71; 95% confidence interval [CI] = 0.58–0.87), whereas survival in the hyperoxemia group did not differ from that in the normoxemia group (aRR = 1.0; 95% CI = 0.87–1.15). The hypercapnia group was less likely to survive to hospital discharge, compared with the normocapnia group (aRR = 0.74; 95% CI = 0.64–0.84), whereas survival in the hypocapnia group did not differ from that in the normocapnia group (aRR = 0.91; 95% CI = 0.74–1.12). Conclusions: Postarrest hypoxemia and hypercapnia were each associated with lower rates of survival to hospital discharge. [ABSTRACT FROM AUTHOR]2 - Published
- 2024
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31. Corrigendum to “2023 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations: Summary From the Basic Life Support; Advanced Life Support; Pediatric Life Support; Neonatal Life Support; Education, Implementation, and Teams; and First Aid Task Forces” [Resuscitation 195 (2024) 109992]
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Berg, Katherine M., Bray, Janet E., Ng, Kee-Chong, Liley, Helen G., Greif, Robert, Carlson, Jestin N., Morley, Peter T., Drennan, Ian R., Smyth, Michael, Scholefield, Barnaby R., Weiner, Gary M., Cheng, Adam, Djärv, Therese, Abelairas-Gómez, Cristian, Acworth, Jason, Andersen, Lars W., Atkins, Dianne L., Berry, David C., Bhanji, Farhan, Bierens, Joost, Bittencourt Couto, Thomaz, Borra, Vere, Böttiger, Bernd W., Bradley, Richard N., Breckwoldt, Jan, Cassan, Pascal, Chang, Wei-Tien, Charlton, Nathan P., Phil Chung, Sung, Considine, Julie, Costa-Nobre, Daniela T., Couper, Keith, Dainty, Katie N., Dassanayake, Vihara, Davis, Peter G., Dawson, Jennifer A., Fernanda de Almeida, Maria, De Caen, Allan R., Deakin, Charles D., Dicker, Bridget, Douma, Matthew J., Eastwood, Kathryn, El-Naggar, Walid, Fabres, Jorge G., Fawke, Joe, Fijacko, Nino, Finn, Judith C., Flores, Gustavo E., Foglia, Elizabeth E., Folke, Fredrik, Gilfoyle, Elaine, Goolsby, Craig A., Granfeldt, Asger, Guerguerian, Anne-Marie, Guinsburg, Ruth, Hatanaka, Tetsuo, Hirsch, Karen G., Holmberg, Mathias J., Hosono, Shigeharu, Hsieh, Ming-Ju, Hsu, Cindy H., Ikeyama, Takanari, Isayama, Tetsuya, Johnson, Nicholas J., Kapadia, Vishal S., Daripa Kawakami, Mandira, Kim, Han-Suk, Kleinman, Monica E., Kloeck, David A., Ko, Ying-Chih, Kudenchuk, Peter, Kule, Amy, Kurosawa, Hiroshi, Lagina, Anthony T., Lauridsen, Kasper G., Lavonas, Eric J., Lee, Henry C., Lin, Yiqun, Lockey, Andrew S., Macneil, Finlay, Maconochie, Ian K., John Madar, R., Malta Hansen, Carolina, Masterson, Siobhan, Matsuyama, Tasuku, McKinlay, Christopher J.D., Meyran, Daniel, Monnelly, Vix, Morrison, Laurie J., Nadkarni, Vinay, Nakwa, Firdose L., Nation, Kevin J., Nehme, Ziad, Nemeth, Michael, Neumar, Robert W., Nicholson, Tonia, Nikolaou, Nikolaos, Nishiyama, Chika, Norii, Tatsuya, Nuthall, Gabrielle A., Ohshimo, Shinchiro, Olasveengen, Theresa M., Gene Ong, Yong-Kwang, Orkin, Aaron M., Parr, Michael J., Patocka, Catherine, Perkins, Gavin D., Perlman, Jeffrey M., Rabi, Yacov, Raitt, James, Ramachandran, Shalini, Ramaswamy, Viraraghavan V., Raymond, Tia T., Reis, Amelia G., Reynolds, Joshua C., Ristagno, Giuseppe, Rodriguez-Nunez, Antonio, Roehr, Charles C., Rüdiger, Mario, Sakamoto, Tetsuya, Sandroni, Claudio, Sawyer, Taylor L., Schexnayder, Steve M., Schmölzer, Georg M., Schnaubelt, Sebastian, Semeraro, Federico, Singletary, Eunice M., Skrifvars, Markus B., Smith, Christopher M., Soar, Jasmeet, Stassen, Willem, Sugiura, Takahiro, Tijssen, Janice A., Topjian, Alexis A., Trevisanuto, Daniele, Vaillancourt, Christian, Wyckoff, Myra H., Wyllie, Jonathan P., Yang, Chih-Wei, Yeung, Joyce, Zelop, Carolyn M., Zideman, David A., and Nolan, Jerry P.
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- 2024
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32. The authors reply:
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Emeriaud, Guillaume, López-Fernández, Yolanda M., Khemani, Robinder G., Emeriaud, Guillaume, López-Fernández, Yolanda M., Khemani, Robinder G., Prabhu Iyer, Narayan, Bembea, Melania, Kwasi Korang, Steven, Steffen, Katherine M., Yehya, Nadir, Smith, Lincoln, Thomas, Neal J., Zimmerman, Jerry J., Erickson, Simon J., Shein, Steven L., Grunwell, Jocelyn R., Dahmer, Mary K., Sapru, Anil, Quasney, Michael W., Flori, Heidi R, Fernandez, Analia, Modesto i Alapont, Vicent, Rimensberger, Peter, Cheifetz, Ira, Rowan, Courtney, Randolph, Adrienne G., Kneyber, Martin, Valentine, Stacey, Kudchadkar, Sapna, Ward, Shan, Nadkarni, Vinay, Curley, Martha A.Q., Bhalla, Anoopindar, Baudin, Florent, Takeuchi, Muneyuki, Cruces, Pablo, Carroll, Christopher L, Napolitano, Natalie, Pons-Odena, Marti, Essouri, Sandrine, Rambaud, Jérome, Barbaro, Ryan, Macrae, Duncan, Dalton, Heidi, Killien, Elizabeth, Maddux, Aline, Man Tse, Sze, Watson, Scott, Nelson Sanchez-Pinto, L., Sauthier, Michaël, Rajapreyar, Prakadeshwari, Jouvet, Philippe, Newth, Christopher, Morrow, Brenda, Agulnik, Asya, Brunow de Carvalho, Werther, Chisti, Mohamod, Hau Lee, Jan, Lobner, Katie, Kysh, Lynn, Pincivy, Alix, and Dodin, Philippe
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- 2024
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33. Contributors
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Abdelmalak, Basem B., Abu-Omar, Yasir, Achilli, Felice, Adams, Sasha D., Aguirre-Bermeo, Hernán, Ahmed, Anas A., Aiello, Salvatore R., Akbari, Ayub, Alarcon, Louis H., Aldo, F. Luke, Alfaro-Maguyon, Maria Estela, Amin, Arpit, Angeli, Paolo, Annoni, Filippo, Antonelli, Massimo, Antongiorgi, Zarah D., Antoniadou, Anastasia, Arnaoutakis, Dean J., Astiz, Mark E., Azoulay, Élie, Baeza, Cristian, Baldisseri, Marie R., Balogh, Zsolt J., Banerjee, Arna, Bansal, Shweta, Barbier, François, Barjaktarevic, Igor, Bassin, Sarice L., Bastarache, Julie A., Baturin, Brian, Bausch, Daniel G., Beaulieu, Yanick, Beaver, Thomas, Bello, Giuseppe, Bellomo, Rinaldo, Bentea, Georgiana, Bermeo-Ovalle, Adriana C., Bernard, Gordon R., Berry, Cherisse, Bierens, Joost, Biffl, Walter L., Bihari, Shailesh, Bleck, Thomas P., Bledsoe, Thomas A., Bloch, Karen C., Boggild, Andrea K., Boncyk, Christina, Bond, Geoffrey J., Bradshaw, Michael J., Brakenridge, Scott, Branson, Richard D., Brimioulle, Serge, Brinson, Erika L., Brocca, Alessandra, Broman, Marcus Ewert, Brook, Itzhak, Brown, Christian J., Brunsvold, Melissa E., Buetti, Niccolò, Bulger, Eileen M., Cain, Christian, Calverley, Peter M.A., Cappelletty, Diane M., Casado-Arroyo, Ruben, Cecconi, Maurizio, Chae, June M., Chawla, Lakhmir S., Chan, Edward D., Chandrashekaran, Satish, Chandrika, Sharad, Chang, Wan-Tsu W., Chen, Dhruti P., Chopra, Amit, Christie, S. Ariane, Christman, John W., Cioci, Alessia C., Clark, Edward G., Cocanour, Christine, Cohen, Mitchell, Cole, Kelli A., Coleman, Lauren, Collins, Caitlin, Cook, Jared, Cooney, Robert N., Corbridge, Thomas, Cornely, Oliver A., Cortes-Lopez, Roxana, Crandall, Marie L., Čretnik, Andrej, Ashley, Chasen, Crouser, Elliott D., Navarro, Jovany Cruz, Curtis, J. Randall, Dalton, Heidi J., Darby, Joseph M., Davies, John D., Dayton, Orrin L., D’Costa, Rohit L., de Smet, Anne Marie G.A., Desai, Mehul A., Deutschman, Clifford, Dexter, Amanda M., Dhillon, Anahat, Muzio, Francesca Di, Diaz, Jose J., Jr., Dixon, Alexandra L., Doelken, Peter, Doidge, James, Dolinak, Joan, Donahoe, Michael, Driscoll, Ian R., Elhassan, Elwaleed A., Elie-Turenne, Marie Carmelle, Elmufdi, Firas, Ely, E. Wesley, Emlet, Lillian L., Emtiazjoo, Amir M., Ershoff, Brent, Estrera, Anthony L., Faggiano, Chiara, Falk, Ronald J., Farmer, Brenna, Farwell, Alan P., Feild, Carinda, Feller-Kopman, David, Hernandez, Samantha Fernandez, Ferrando-Vivas, Paloma, Ferrer, Miguel, Fisher, Caleb, Fishman, Guy, Flock, Jens, IV, Forman, Lisa, Fortune, Brett E., Freedman, Barry I., Fried, Elchanan, Gambino, Carmine, Gardiner, Dale, Gattinoni, Luciano, Gazmuri, Raúl J., Gehr, Todd W.B., Gerlach, Herwig, Ghobrial, R. Mark, Giamarellou, Helen, Ginsberg, Fredric, Gleason, Thomas G., Gorcsan, John, III, Gozal, Yaacov, Gradon, Jeremy D., Graves, Cornelia R., Greco, Massimiliano, Gregoretti, Cesare, Gropper, Michael A., Gubbins, Paul O., Gudzenko, Vadim, Gunnerson, Kyle J., Gunst, Jan, Gustafson, Kate S., Haase, Michael, Haase-Fielitz, Anja, Habib, Fahim, Harbrecht, Brian G., Harrison, David, Hill, Nicholas S., Hiremath, Swapnil, Hladik, Gerald A., Hoffman, Marcus K., Hollenberg, Steven M., Hoste, Eric A.J., Hsu, Albert, Huang, David T., Huber, Thomas S., Huggins, J. Terrill, Hamera, Joseph A., Ibrahim, Joseph Abdellatif, Isaac, Margaret L., Jabbour, Ibrahim I., Jacquerioz, Frederique A., Jadhav, Ashutosh, P., Jain, Sumeet V., Jansson, Paul S., Jeng, Eric I., Jozwiak, Mathieu, Kabrhel, Christopher, Kain, Taylor, Kaufman, David C., Kaynar, A. Murat, Kellum, John A., Kerwin, Andrew J., Kidd, Jason, Kilic, Arman, Kim, Donghee, Knudson, M. Margaret, Koehler, Philipp, Kollef, Marin H., Kormos, Robert L., Košir, Roman, Kotloff, Robert M., Kotzen, Elizabeth S., Koulenti, Despoina, Kratzert, Wolf Benjamin, Kumar, Anand, Langness, Simone, Lee, Jin, Leisman, Daniel, Leung, Angela M., Levin, Phillip D., Levy, Jerrold H., Levy, Mitchell M., Lewandowski, David C., Lewis, Anthony J., Bassi, Gianluigi Li, Liebman, Scott, Linas, Stuart L., Linefsky, Jason P., Lipman, Jeffrey, Lipsett, Pamela A., Lipshutz, Angela K.M., Loftus, Tyler J., Lopez-Magallon, Alejandro J., Lother, Sylvain, MacIntyre, Neil R., Magder, Sheldon, Maggiolini, Stefano, Mahajan, Aman, Maine, Rebecca, Maisch, Bernhard, Mancebo, Jordi, Mann, Henry J., Manocha, Sanjay, Margulies, Daniel R., Marik, Paul E., Marini, John J., Markan, Sandeep, Martinez-Camacho, Alvaro, Marx, William, Mayr, Florian B., Mazariegos, George V., McClave, Stephen A., McGloughlin, Steven A., McLean, Anna W., McMichael, Ali B.V., Meltzer, Joseph S., Merola, Raffaele, Messina, Antonio, Micek, Scott T., Mohammed, Subhan, Mohr, Alicia M., Monard, Celine, Monnet, Xavier, Montford, John, Moore, Ernest E., Moore, Frederick A., Moore, Hunter B., Moore, Laura J., Moore, Peter K., Mort, Thomas C., Motayar, Nasim, Muñoz, Ricardo A., Naber, Kurt G., Nadkarni, Vinay M., Nair, Girish B., Namias, Nicholas, Krishna, Vinay Narasimha, Nassikas, Nicholas J., New, Melissa L., Nguyen-Lee, Jennifer, Niccum, David E., Niederman, Michael S., Niven, Alexander S., Oddo, Mauro, Omer, Endashaw, Oostdijk, Evelien A.N., Opal, Steven M., Opdam, Helen I., Otto, Catherine M., Pannu, Sonal R., Parrillo, Joseph E., Pasero, Daniela, Patel, Rohit Pravin, Paterson, David L., Pavot, Arthur, Peitzman, Andrew B., Peluso, Lorenzo, Penoyer, Daleen Aragon, Pepe, Judith L., Pergakis, Melissa B., Peters, Steve G., Phelps, Mitch A., Picard, Fabien, Pilatz, Adrian, Piovesana, Giovanni, Pitisci, Lorenzo, Pollandt, Sebastian, Protti, Alessandro, Puyana, Juan Carlos, Puzio, Thaddeus J., Ra, Jin H., Raghu, Vikram K., Ramsingh, Davinder, Ranieri, V. Marco, Reynolds, Joshua C., Rimmelé, Thomas, Ristic, Arsen D., Rizzo, LTC Julie A., Robertson, Claudia S., Robinson, Christopher P., Robinson, Todd W., Roche-Campo, Ferran, Rodriguez, Ryan, Romito, Bryan T., Rosenthal, Martin D., Rowan, Daniel J., Rubenfeld, Gordon D., Rubin, Lewis J., Salgado, Juan C., Sambin, Pauline, Sánchez-de-Toledo, Joan, Santonocito, Cristina, Sappington, Penny Lynn, Sartelli, Massimo, Savelieva, Irina, Schott, Christopher K., Schouten, Jeroen A., Schreiber, Martin A., Schulman, Carl, See, Emily J., Seese, Laura M., Selickman, John, Sempsrott, Justin, Sethuraman, Kinjal N., Shemie, Sam D., Shiloh, Ariel L., Silvis, Jennifer L., Singer, Pierre, Singh, Sumit P., Sreedharan, Roshni, Steinberg, Alexis, Streichenberger, Antoine, Szpilman, David, Szychowiak, Piotr, Taccone, Fabio Silvio, Tanaka, Akiko, Tanner, Colby, Tawfik, Pierre N., Teboul, Jean-Louis, Teitelbaum, Isaac, Terragni, Pierpaolo, Thom, Stephen R., Thompson, Ashley, Timsit, Jean-Francois, Tisherman, Samuel A., Todd, S. Rob, Tolwani, Ashita J., Tonetti, Tommaso, Tonon, Marta, Torres, Antoni, Toscano, Nicole C., Tsai, Lillian L., Turner, Cody D., Tyndall, J. Adrian, Tzeng, Edith, Berghe, Greet Van den, van Zanten, Arthur R.H., Vanommeslaeghe, Floris, Vanzant, Erin L., Venkataraman, Ramesh, Verdiner, Ricardo E., Vincent, Jean-Louis, Wagenlehner, Florian M.E., Walker, Paul Phillip, Walley, Keith, Walter, James, Wang, Tisha, Wang, Kevin K.W., Ward, Nicholas S., Ware, Lorraine B., Warrillow, Stephen, Watson, Gregory A., Wechsler, Lawrence R., Weissman, Charles, Wille, Keith M., Wunderink, Richard G., Yang, Zhihui, Yende, Sachin, Yi, Stephanie Grace, Young, Paul, Zeitler, Evan, and Zhao, Frank Z.
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- 2024
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34. Characteristics of Pediatric In-Hospital Cardiac Arrests and Resuscitation Duration.
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O'Halloran, Amanda, Morgan, Ryan W., Kennedy, Kevin, Berg, Robert A., Gathers, Cody-Aaron, Naim, Maryam Y., Nadkarni, Vinay, Reeder, Ron, Topjian, Alexis, Wolfe, Heather, Kleinman, Monica, Chan, Paul S., and Sutton, Robert M.
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- 2024
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35. Intra-Arrest Transport vs On-Scene Cardiopulmonary Resuscitation for Children—Scoop and Run vs Stay and Play.
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Nadkarni, Vinay M., Tijssen, Janice, and Denny, Vanessa
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- 2024
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36. ¿Debemos simplificar el método o, por el contrario, entrenar más y mejor?... Rompiendo barreras y cambiando la cultura de la Reanimación
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Trastoy-Quintela, Javier, Ramachandra, Geethanjali, and Nadkarni, Vinay
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- 2024
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37. Mitigation and Outcomes of Difficult Bag-Mask Ventilation in Critically Ill Children
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Daigle, C. Hunter, Laverriere, Elizabeth K., Bruins, Benjamin B., Lockman, Justin L., Fiadjoe, John E., McGowan, Nancy, Napolitano, Natalie, Shults, Justine, Nadkarni, Vinay M., and Nishisaki, Akira
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- 2024
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38. Harms Associated with Tracheal Reintubation After Unplanned Extubation: A Retrospective Cohort Study
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Malone, Mathew P., Harwayne-Gidansky, Ilana, Sanders, Ronald C., Napolitano, Natalie, Pham, Jennifer, Polikoff, Lee, Register, Melinda, Tarquinio, Keiko M., Shults, Justine, Krawiec, Conrad, Mallory, Palen, Breuer, Ryan K., Shenoi, Asha N., Wollny, Krista, Parsons, Simon J., Kandil, Sarah B., Pinto, Matthew, Gladen, Kelsey M., Dewan, Maya, Graciano, Ana Lia, Nett, Sholeen, Giuliano, John S., Krishna, Ashwin S., Ducharme-Crevier, Laurence, Talukdar, Andrea, Lee, Jan Hau, Miksa, Michael, Lee, Anthony, Ahmed, Aziez, Page-Goertz, Christopher, Jung, Philipp, Scott, Briana L., Kelly, Serena P., Al-Subu, Awni, Spear, Debbie, Allen, Lauren, Sizemore, Johnna, Kasagi, Mioko, Nagai, Yuki, Toal, Megan, Biagas, Katherine, Nadkarni, Vinay, and Nishisaki, Akira
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- 2024
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39. Risk Factors and Outcomes for Recurrent Pediatric In-Hospital Cardiac Arrest: Retrospective Cohort Study from the American Heart Association's Get with the Guidelines-Resuscitation Registry
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Frazier, Maria E., Brown, Stephanie R., O'Halloran, Amanda, Raymond, Tia, Kleinman, Monica E., Sutton, Robert M., Roberts, Joan, Tegtmeyer, Ken, Wolfe, Heather A., Nadkarni, Vinay, and Dewan, Maya
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- 2024
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40. The Association of Teamwork and Adverse Tracheal Intubation–Associated Events in Advanced Airway Management in the PICU
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Jennings, John F., Nett, Sholeen, Umoren, Rachel, Murray, Robert, Kessel, Aaron, Napolitano, Natalie, Adu-Darko, Michelle, Biagas, Katherine, Jung, Philipp, Spear, Debra, Parsons, Simon, Breuer, Ryan, Meyer, Keith, Malone, Matthew, Shenoi, Asha, Lee, Anthony, Mallory, Palen, Al-Subu, Awni, Tarquinio, Keiko, Glater, Lily, Toal, Megan, Lee, Jan Hau, Pinto, Matthew, Polikoff, Lee, Own, Erin, Toedt-Pingel, Iris, Kasagi, Mioko, Ducharme-Crevier, Laurence, Motomura, Makoto, Gima, Masafumi, Kelly, Serena, Panisello, Josep, Nuthall, Gabrielle, Gladen, Kelsey, Shults, Justine, Nadkarni, Vinay, and Nishisaki, Akira
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- 2024
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41. Brief report: incidence and outcomes of pediatric tracheal intubation-associated cardiac arrests in the ICU-RESUS clinical trial.
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Nishisaki A, Reeder RW, McGovern EL, Ahmed T, Bell MJ, Bishop R, Bochkoris M, Burns C, Carcillo JA, Carpenter TC, Diddle W, Federman M, Fink EL, Franzon D, Frazier AH, Friess SH, Graham K, Hall M, Hehir DA, Horvat CM, Huard LL, Maa T, Manga A, McQuillen P, Meert KL, Morgan RW, Mourani PM, Nadkarni VM, Naim MY, Notterman D, Palmer CA, Sapru A, Schneiter C, Sharron MP, Srivastava N, Viteri S, Wessel D, Wolfe HA, Yates AR, Zuppa AF, Sutton RM, and Berg RA
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- Humans, Male, Female, Child, Preschool, Infant, Child, Incidence, Cardiopulmonary Resuscitation methods, Cardiopulmonary Resuscitation statistics & numerical data, Cardiopulmonary Resuscitation adverse effects, Intensive Care Units, Pediatric statistics & numerical data, Intensive Care Units, Pediatric organization & administration, Adolescent, Intubation, Intratracheal statistics & numerical data, Intubation, Intratracheal adverse effects, Intubation, Intratracheal methods, Heart Arrest therapy, Heart Arrest mortality, Heart Arrest epidemiology
- Abstract
Background: Tracheal intubation (TI)-associated cardiac arrest (TI-CA) occurs in 1.7% of pediatric ICU TIs. Our objective was to evaluate resuscitation characteristics and outcomes between cardiac arrest patients with and without TI-CA., Methods: Secondary analysis of cardiac arrest patients in both ICU-RESUS trial and ancillary CPR-NOVA study. The primary exposure was TI-CA, defined as cardiac arrest occurred during TI procedure or within 20 min after endotracheal tube placement. The primary outcome was survival to hospital discharge with favorable neurological outcome (Pediatric Cerebral Performance Category score 1-3 or unchanged)., Results: Among 315 children with cardiac arrests, 48 (15.2%) met criteria for TI-CA. Pre-existing medical conditions were similar between groups. Pre-arrest non-invasive mechanical ventilation was more common among TI-CA patients (18/48, 37.5%) compared to non-TI-CA patients (35/267, 13.1%). In 48% (23/48), the TI-CA occurred within 20 min after intubation (i.e., not during intubation). Duration of CPR was longer in TI-CA patients (median 11.0 min, interquartile range [IQR]: 2.5, 35.5) than non-TI-CA patients (median 5.0 min, IQR 2.0, 21.0), p = 0.03. Return of spontaneous circulation occurred in 32/48 (66.7%) TI-CA versus 186/267 (69.7%) non-TI-CA, p = 0.73. Survival to hospital discharge with favorable neurological outcome occurred in 29/48 (60.4%) TI-CA versus 146/267 (54.7%) non-TI-CA, p = 0.53., Conclusions: Fifteen percent of these pediatric ICU cardiac arrests were associated with TI. Half of TI-CA occurred after endotracheal tube placement. While duration of CPR was longer in TI-CA patients, there were no differences in unadjusted outcomes following TI-CA versus non-TI-CA., Trial Registration: The ICU-RESUS (ClinicalTrials.gov Identifier: NCT02837497)., (© 2024. The Author(s).)
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- 2024
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42. Barriers and facilitators when seeking healthcare for septic children in Ghana: a single-centre qualitative study of patient caregivers and emergency department clinicians.
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Denny VC, Appiah JA, Nadkarni VM, Dassah E, Gyimah Mensah E, Kwabena Adjei T, Amisah J, Nettey G, Owusu L, Woods-Hill CZ, Wolfe HA, James EJG, and Ruhama Acheampong P
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- Humans, Ghana epidemiology, Male, Female, Child, Child, Preschool, Adult, Infant, Interviews as Topic, Sepsis therapy, Sepsis nursing, Emergency Service, Hospital, Caregivers psychology, Qualitative Research, Patient Acceptance of Health Care psychology, Patient Acceptance of Health Care statistics & numerical data, Health Services Accessibility
- Abstract
Background/purpose: Sepsis is a leading cause of morbidity, mortality and healthcare utilisation for children worldwide, particularly in resource-limited regions. In Kumasi, Ghana, organ system failure and mortality in children who present to the emergency department (ED) with symptoms of sepsis are often due to late presentation and lack of recognition and implementation of time-critical evidence-based interventions. The purpose of this study was to assess the barriers and facilitators for families in seeking healthcare for their septic children; and to understand the barriers and facilitators for ED providers in Kumasi to recognise and implement sepsis bundle interventions., Design: Single-centre qualitative interviews of 39 caregivers and 35 ED providers in a teaching hospital in Kumasi, Ghana., Results: Thematic analysis of data from caregivers about barriers included: fear of hospital, finances, transportation, delay from referring hospital, cultural/spiritual differences, limited autonomy and concerns with privacy and confidentiality. Negative impacts on family life included financial strain and neglect of other children. ED providers reported barriers included: lack of training, poor work environment and accessibility of equipment. Facilitators from caregivers and providers included some support from the National Health Insurance. Caregivers reported having positive experiences with frontline clinicians, which encouraged them to return to seek health services., Implications: Qualitative structured interviews identified facilitator and critical barrier themes about seeking healthcare, and sepsis identification/management in the paediatric population arriving for care in our centre in Kumasi, Ghana. This study highlights significant deficiencies in healthcare systems that make sepsis management challenging in these settings., Competing Interests: Competing interests: None declared., (© Author(s) (or their employer(s)) 2024. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.)
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- 2024
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43. Early bolus epinephrine administration during pediatric cardiopulmonary resuscitation for bradycardia with poor perfusion: an ICU-resuscitation study.
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O'Halloran AJ, Reeder RW, Berg RA, Ahmed T, Bell MJ, Bishop R, Bochkoris M, Burns C, Carcillo JA, Carpenter TC, Dean JM, Diddle JW, Federman M, Fernandez R, Fink EL, Franzon D, Frazier AH, Friess SH, Graham K, Hall M, Hehir DA, Horvat CM, Huard LL, Kienzle MF, Kilbaugh TJ, Maa T, Manga A, McQuillen PS, Meert KL, Mourani PM, Nadkarni VM, Naim MY, Notterman D, Pollack MM, Sapru A, Schneiter C, Sharron MP, Srivastava N, Tilford B, Topjian AA, Viteri S, Wessel D, Wolfe HA, Yates AR, Zuppa AF, Sutton RM, and Morgan RW
- Subjects
- Humans, Male, Female, Child, Preschool, Child, Infant, Adolescent, Intensive Care Units statistics & numerical data, Intensive Care Units organization & administration, Epinephrine administration & dosage, Epinephrine therapeutic use, Cardiopulmonary Resuscitation methods, Cardiopulmonary Resuscitation statistics & numerical data, Bradycardia drug therapy, Bradycardia therapy
- Abstract
Background: Half of pediatric in-hospital cardiopulmonary resuscitation (CPR) events have an initial rhythm of non-pulseless bradycardia with poor perfusion. Our study objectives were to leverage granular data from the ICU-RESUScitation (ICU-RESUS) trial to: (1) determine the association of early epinephrine administration with survival outcomes in children receiving CPR for bradycardia with poor perfusion; and (2) describe the incidence and time course of the development of pulselessness., Methods: Prespecified secondary analysis of ICU-RESUS, a multicenter cluster randomized trial of children (< 19 years) receiving CPR in 18 intensive care units in the United States. Index events (October 2016-March 2021) lasting ≥ 2 min with a documented initial rhythm of bradycardia with poor perfusion were included. Associations between early epinephrine (first 2 min of CPR) and outcomes were evaluated with Poisson multivariable regression controlling for a priori pre-arrest characteristics. Among patients with arterial lines, intra-arrest blood pressure waveforms were reviewed to determine presence of a pulse during CPR interruptions. The temporal nature of progression to pulselessness was described and outcomes were compared between patients according to subsequent pulselessness status., Results: Of 452 eligible subjects, 322 (71%) received early epinephrine. The early epinephrine group had higher pre-arrest severity of illness and vasoactive-inotrope scores. Early epinephrine was not associated with survival to discharge (aRR 0.97, 95%CI 0.82, 1.14) or survival with favorable neurologic outcome (aRR 0.99, 95%CI 0.82, 1.18). Among 186 patients with invasive blood pressure waveforms, 118 (63%) had at least 1 period of pulselessness during the first 10 min of CPR; 86 (46%) by 2 min and 100 (54%) by 3 min. Sustained return of spontaneous circulation was highest after bradycardia with poor perfusion (84%) compared to bradycardia with poor perfusion progressing to pulselessness (43%) and bradycardia with poor perfusion progressing to pulselessness followed by return to bradycardia with poor perfusion (62%) (p < 0.001)., Conclusions: In this cohort of pediatric CPR events with an initial rhythm of bradycardia with poor perfusion, we failed to identify an association between early bolus epinephrine and outcomes when controlling for illness severity. Most children receiving CPR for bradycardia with poor perfusion developed subsequent pulselessness, 46% within 2 min of CPR onset., (© 2024. The Author(s).)
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- 2024
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44. Early Cardiac Arrest Hemodynamics, End-Tidal C o2 , and Outcome in Pediatric Extracorporeal Cardiopulmonary Resuscitation: Secondary Analysis of the ICU-RESUScitation Project Dataset (2016-2021).
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Yates AR, Naim MY, Reeder RW, Ahmed T, Banks RK, Bell MJ, Berg RA, Bishop R, Bochkoris M, Burns C, Carcillo JA, Carpenter TC, Dean JM, Diddle JW, Federman M, Fernandez R, Fink EL, Franzon D, Frazier AH, Friess SH, Graham K, Hall M, Hehir DA, Horvat CM, Huard LL, Maa T, Manga A, McQuillen PS, Morgan RW, Mourani PM, Nadkarni VM, Notterman D, Pollack MM, Sapru A, Schneiter C, Sharron MP, Srivastava N, Tilford B, Viteri S, Wessel D, Wolfe HA, Yeh J, Zuppa AF, Sutton RM, and Meert KL
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- Infant, Child, Humans, Carbon Dioxide, Hemodynamics, Intensive Care Units, Retrospective Studies, Cardiopulmonary Resuscitation methods, Heart Arrest therapy
- Abstract
Objectives: Cannulation for extracorporeal membrane oxygenation during active extracorporeal cardiopulmonary resuscitation (ECPR) is a method to rescue patients refractory to standard resuscitation. We hypothesized that early arrest hemodynamics and end-tidal C o2 (ET co2 ) are associated with survival to hospital discharge with favorable neurologic outcome in pediatric ECPR patients., Design: Preplanned, secondary analysis of pediatric Utstein, hemodynamic, and ventilatory data in ECPR patients collected during the 2016-2021 Improving Outcomes from Pediatric Cardiac Arrest study; the ICU-RESUScitation Project (ICU-RESUS; NCT02837497)., Setting: Eighteen ICUs participated in ICU-RESUS., Patients: There were 97 ECPR patients with hemodynamic waveforms during cardiopulmonary resuscitation., Interventions: None., Measurements and Main Results: Overall, 71 of 97 patients (73%) were younger than 1 year old, 82 of 97 (85%) had congenital heart disease, and 62 of 97 (64%) were postoperative cardiac surgical patients. Forty of 97 patients (41%) survived with favorable neurologic outcome. We failed to find differences in diastolic or systolic blood pressure, proportion achieving age-based target diastolic or systolic blood pressure, or chest compression rate during the initial 10 minutes of CPR between patients who survived with favorable neurologic outcome and those who did not. Thirty-five patients had ET co2 data; of 17 survivors with favorable neurologic outcome, four of 17 (24%) had an average ET co2 less than 10 mm Hg and two (12%) had a maximum ET co2 less than 10 mm Hg during the initial 10 minutes of resuscitation., Conclusions: We did not identify an association between early hemodynamics achieved by high-quality CPR and survival to hospital discharge with favorable neurologic outcome after pediatric ECPR. Candidates for ECPR with ET co2 less than 10 mm Hg may survive with favorable neurologic outcome., Competing Interests: Drs. Yates’s, Naim’s, Reeder’s, Berg’s, Carpenter’s, Dean’s, Fink’s, Frazier’s, Hall’s, Manga’s, Mourani’s, Sapru’s, Wessel’s, Wolfe’s, Zuppa’s, and Meert’s institution received funding from the National Institutes of Health (NIH). Drs. Yates, Naim, Reeder, Banks, Berg, Carcillo, Carpenter, Dean, Fink, Franzon, Frazier, Freiss, Hall, Horvat, McQuillen, Mourani, Pollack, Sapru, Schneiter, Wessel, Zuppa, Sutton, and Meert received support for article research from the NIH. Drs. Banks’s, Carcillo’s, Horvat’s, Maa’s, McQuillen’s, Pollack’s, and Schneiter’s institutions received funding from the National Institute for Child Health and Human Development. Dr. Banks disclosed government work. Drs. Carcillo’s, Maa’s, and Sutton’s institutions received funding from the National Heart, Lung, and Blood Institute (NHLBI). Dr. Carcillo’s institution received funding from the National Institute for General Medical Sciences. Dr. Diddle disclosed that he is a consultant with Mallinckrodt Pharmaceuticals. Dr. Franzon received funding from Health Navigator Foundation; she disclosed that she is a site investigator for a multisite NIH funded project. Dr. Frazier’s institution received funding from the Neurocritical Care Society and the American Board of Pediatrics. Dr. Hall received funding from AbbVie, Kiadis, and the American Board of Pediatrics. Dr. Morgan’s institution received funding from the NHLBI (K23HL148541). Dr. Wolfe received funding from The Debriefing Academy. The remaining authors have disclosed that they do not have any potential conflicts of interest., (Copyright © 2024 by the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies.)
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- 2024
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45. Adverse Tracheal Intubation Events in Critically Ill Underweight and Obese Children: Retrospective Study of the National Emergency Airway for Children Registry (2013-2020).
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Gladen KM, Tellez D, Napolitano N, Edwards LR, Sanders RC Jr, Kojima T, Malone MP, Shults J, Krawiec C, Ambati S, McCarthy R, Branca A, Polikoff LA, Jung P, Parsons SJ, Mallory PP, Komeswaran K, Page-Goertz C, Toal MC, Bysani GK, Meyer K, Chiusolo F, Glater-Welt LB, Al-Subu A, Biagas K, Hau Lee J, Miksa M, Giuliano JS Jr, Kierys KL, Talukdar AM, DeRusso M, Cucharme-Crevier L, Adu-Arko M, Shenoi AN, Kimura D, Flottman M, Gangu S, Freeman AD, Piehl MD, Nuthall GA, Tarquinio KM, Harwayne-Gidansky I, Hasegawa T, Rescoe ES, Breuer RK, Kasagi M, Nadkarni VM, and Nishisaki A
- Subjects
- Infant, Child, Humans, Infant, Newborn, Child, Preschool, Adolescent, Retrospective Studies, Overweight etiology, Thinness complications, Thinness epidemiology, Intubation, Intratracheal adverse effects, Intubation, Intratracheal methods, Hypoxia epidemiology, Hypoxia etiology, Registries, Critical Illness, Pediatric Obesity complications, Pediatric Obesity epidemiology
- Abstract
Objectives: Extremes of patient body mass index are associated with difficult intubation and increased morbidity in adults. We aimed to determine the association between being underweight or obese with adverse airway outcomes, including adverse tracheal intubation (TI)-associated events (TIAEs) and/or severe peri-intubation hypoxemia (pulse oximetry oxygen saturation < 80%) in critically ill children., Design/setting: Retrospective cohort using the National Emergency Airway for Children registry dataset of 2013-2020., Patients: Critically ill children, 0 to 17 years old, undergoing TI in PICUs., Interventions: None., Measurements and Main Results: Registry data from 24,342 patients who underwent TI between 2013 and 2020 were analyzed. Patients were categorized using the Centers for Disease Control and Prevention weight-for-age chart: normal weight (5th-84th percentile) 57.1%, underweight (< 5th percentile) 27.5%, overweight (85th to < 95th percentile) 7.2%, and obese (≥ 95th percentile) 8.2%. Underweight was most common in infants (34%); obesity was most common in children older than 8 years old (15.1%). Underweight patients more often had oxygenation and ventilation failure (34.0%, 36.2%, respectively) as the indication for TI and a history of difficult airway (16.7%). Apneic oxygenation was used more often in overweight and obese patients (19.1%, 19.6%) than in underweight or normal weight patients (14.1%, 17.1%; p < 0.001). TIAEs and/or hypoxemia occurred more often in underweight (27.1%) and obese (24.3%) patients ( p < 0.001). TI in underweight children was associated with greater odds of adverse airway outcome compared with normal weight children after adjusting for potential confounders (underweight: adjusted odds ratio [aOR], 1.09; 95% CI, 1.01-1.18; p = 0.016). Both underweight and obesity were associated with hypoxemia after adjusting for covariates and site clustering (underweight: aOR, 1.11; 95% CI, 1.02-1.21; p = 0.01 and obesity: aOR, 1.22; 95% CI, 1.07-1.39; p = 0.002)., Conclusions: In underweight and obese children compared with normal weight children, procedures around the timing of TI are associated with greater odds of adverse airway events., Competing Interests: Ms. Napolitano’s, Dr. Shults’s, Dr. Nadkarni’s, and Dr. Nishisaki’s institution received funding from the Agency for Healthcare Research and Quality (R18HS024511). Ms. Napolitano’s institution received funding from Dräger, Actuated Medical, and Philips Respironics; they received support for article research from Timpel and VERO-Biotech. Dr. Krawiec received funding from New England Journal of Medicine Healer Cases and Carle Illinois School of Medicine Admissions Committee. Dr. Polikoff received funding from Novavax. Dr. Lee’s institution received funding from National Research Medical Council, Singapore. Dr. Shenoi is an elected member of the Society of Critical Care Medicine (SCCM) Council of the SCCM. Dr. Peihl disclosed that he is founder and Chief Medical Officer of 410 Medical; his institution received funding the Department of Defense (grants: USSOCOM W81XWH-22-C-0002, USAF SBIR AF212-CSO1 Phase II, F2-15653 USAF, SBIR AF211-CSO1 Phase II, F2-15254). Dr. Hasegawa disclosed work for hire. Dr. Nishisaki’s institution received funding from Chiesi USA, AHRA, and the National Institute of Child Health and Human Development. The remaining authors have disclosed that they do not have any potential conflicts of interest., (Copyright © 2023 by the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies.)
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- 2024
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46. Safety of primary nasotracheal intubation in the pediatric intensive care unit (PICU).
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Ducharme-Crevier L, Furlong-Dillard J, Jung P, Chiusolo F, Malone MP, Ambati S, Parsons SJ, Krawiec C, Al-Subu A, Polikoff LA, Napolitano N, Tarquinio KM, Shenoi A, Talukdar A, Mallory PP, Giuliano JS Jr, Breuer RK, Kierys K, Kelly SP, Motomura M, Sanders RC Jr, Freeman A, Nagai Y, Glater-Welt LB, Wilson J, Loi M, Adu-Darko M, Shults J, Nadkarni V, Emeriaud G, and Nishisaki A
- Abstract
Background: Nasal tracheal intubation (TI) represents a minority of all TI in the pediatric intensive care unit (PICU). The risks and benefits of nasal TI are not well quantified. As such, safety and descriptive data regarding this practice are warranted., Methods: We evaluated the association between TI route and safety outcomes in a prospectively collected quality improvement database (National Emergency Airway Registry for Children: NEAR4KIDS) from 2013 to 2020. The primary outcome was severe desaturation (SpO
2 > 20% from baseline) and/or severe adverse TI-associated events (TIAEs), using NEAR4KIDS definitions. To balance patient, provider, and practice covariates, we utilized propensity score (PS) matching to compare the outcomes of nasal vs. oral TI., Results: A total of 22,741 TIs [nasal 870 (3.8%), oral 21,871 (96.2%)] were reported from 60 PICUs. Infants were represented in higher proportion in the nasal TI than the oral TI (75.9%, vs 46.2%), as well as children with cardiac conditions (46.9% vs. 14.4%), both p < 0.001. Severe desaturation or severe TIAE occurred in 23.7% of nasal and 22.5% of oral TI (non-adjusted p = 0.408). With PS matching, the prevalence of severe desaturation and or severe adverse TIAEs was 23.6% of nasal vs. 19.8% of oral TI (absolute difference 3.8%, 95% confidence interval (CI): - 0.07, 7.7%), p = 0.055. First attempt success rate was 72.1% of nasal TI versus 69.2% of oral TI, p = 0.072. With PS matching, the success rate was not different between two groups (nasal 72.2% vs. oral 71.5%, p = 0.759)., Conclusion: In this large international prospective cohort study, the risk of severe peri-intubation complications was not significantly higher. Nasal TI is used in a minority of TI in PICUs, with substantial differences in patient, provider, and practice compared to oral TI.A prospective multicenter trial may be warranted to address the potential selection bias and to confirm the safety of nasal TI., Competing Interests: Competing interestsThe authors declare that they have no competing interests., (© The Author(s) 2024.)- Published
- 2024
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