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The Julia programming language was created 10 years ago and is now a mature and stable language with a large ecosystem including more than 8,000 third-party packages. It was designed for scientific programming to be a high-level and dynamic language as Python is, while achieving runtime performances comparable to C/C++ or even faster. With this, we ask ourselves if the Julia language and its ecosystem is ready now for its adoption by the High Energy Physics community. We will report on a number of investigations and studies of the Julia language that have been done for various representative HEP applications, ranging from computing intensive initial data processing of experimental data and simulation, to final interactive data analysis and plotting. Aspects of collaborative code development of large software within a HEP experiment has also been investigated: scalability with large development teams, continuous integration and code test, code reuse, language interoperability to enable an adiabatic migration of packages and tools, software installation and distribution, training of the community, benefit from development from industry and academia from other fields.

Failing to address Obstructive Sleep Apnea (OSA) in Down Syndrome (DS) patients can have serious consequences, leading to increased mortality. Moreover, a notable portion of individuals find it challenging to tolerate Continuous Positive Airway Pressure (CPAP). Therefore, this study aims to share our experiences in treating adult DS patients with moderate to severe OSA who don't tolerate CPAP using various surgical approaches. A retrospective analytical study including 20 DS with moderate to severe/very severe OSA who had no tolerance to Continuous Positive Airway Pressure (CPAP) was conducted. Regarding the individual skeletal characteristics of each patient various orthognathic surgery techniques were performed. Two in-hospital polysomnographies (PSG) were undertaken for every patient; one before the surgical procedure, while another was performed between 6 and 60 months of the follow-up post-surgery period. Polysomnographic variables were analyzed in this study such as AHI, ODI, and T90, which all showed statistically significant improvement after surgery with a p value in the Wilcoxon test <0,01. These results have remained stable over time, with no recurrences of OSA observed over the five years of follow-up. Thus, orthognathic surgery may be the only viable option for individuals with DS who are unable to tolerate CPAP., Competing Interests: Declaration of Competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Published by Elsevier Ltd.)