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Abstract Background The triglyceride-glucose (TyG) index, identified as a reliable indicator of insulin resistance (IR), was reported to be associated with stroke recurrence and morbidity in the general population and critically ill patients. However, the relationship in liver transplantation (LT) recipients remains unknown. This study aimed to investigate the correlation between the TyG index and post-LT stroke along with all-cause mortality and further assess the influence of IR on the LT recipients’ prognosis. Methods The retrospective cohort study enrolled 959 patients who underwent LT at a university-based medical centre between January 2015 and January 2021. The participants were divided into three groups according to their TyG index tertiles. The primary outcome was post-LT stroke. Multivariate logistic regression, COX proportional hazards regression, and restricted cubic spline RCS were used to examine the association between the TyG index and outcomes in LT recipients. Results With a median TyG index of 8.23 (7.78–8.72), 780 (87.18% males) patients were eventually included. The incidence of post-LT stroke was 5.38%, and the in-hospital, 1-year, and 3-year mortality rates were 5.54%, 13.21%, and 15.77%, respectively. Multivariate regression analysis showed an independent association between the TyG index and an increased risk of post-LT stroke [adjusted odds ratio (aOR), 3.398 (95% confidence interval [CI]: 1.371–8.426) P = 0. 008], in-hospital mortality [adjusted hazard ratio (aHR), 2.326 (95% CI: 1.089–4.931) P = 0.025], 1-year mortality [aHR, 1.668 (95% CI: 1.024–2.717) P = 0.039], and 3-year mortality [aHR, 1.837 (95% CI: 1.445–2.950) P = 0.012]. Additional RCS analysis also suggested a linear increase in the risk of postoperative stroke with elevated TyG index (P for nonlinearity = 0.480). Conclusions The TyG index may be a valuable and reliable indicator for assessing stroke risk and all-cause mortality in patients undergoing LT, suggesting its potential relevance in improving risk stratification during the peri-LT period.

Background: We aimed to explore the potential risk factors and short-term prognosis for SIRS after thermal ablation of hepatocellular carcinoma (HCC). Methods: Data from patients with HCC who underwent thermal ablation in the Third Affiliated Hospital of Sun Yat-sen University between January 2015 and August 2021 were retrieved from the perioperative database. Pre-, intra- and postoperative data between SIRS group and non-SIRS group were compared and multivariate logistic regression analysis was performed to identify the risk factors for SIRS after thermal ablation. Results: A total of 1491 patients were enrolled and 234 (15.7 %) patients developed SIRS after thermal ablation. Compared with those without SIRS, patients with SIRS had a longer hospital stay, higher hospitalization costs and higher risk of more severe postoperative complications. In the multivariate logistic regression analysis, current smoking (OR 1.58, 95 %CI 1.09–2.29), decreased HCT (OR 1.51,95 %CI 1.11–2.04), NEUT < 1.5 × 109/L(OR 1.74, 95 %CI 1.14–2.65), NEUT% < 0.5 or > 0.7 (OR 1.36, 95 %CI 1.01–1.83) and PT > 16.3s (OR 2.42, 95 %CI 1.57–3.74) were significantly associated with postoperative SIRS. Conclusions: Current smoking, decreased HCT, neutropenia, abnormal percentage of neutrophils and prolonged PT are the independent risk factors for SIRS after thermal ablation of HCC, which worsens outcomes of patients. This study can help identify high-risk population and guide appropriate care so as to reduce the incidence of postoperative SIRS.

Résumé: L’étude que nous envisageons s’intéresse à l’instance de réception dans le système de communication. Dans le champ qui est le nôtre, l’analyse du discours, l’accent est plus mis sur l’instance émettrice et sa production. Même lorsqu’on s’occupe du récepteur, c’est dans le discours du locuteur qu’on va chercher ses traces. Il nous semble qu’il est tout aussi important de voir dans quelle mesure et selon quelles modalités le discours du locuteur impacte réellement l’auditoire auquel il est adressé. Nous postulons que cette analyse est possible en nous penchant sur les retours de l’auditoire par rapport au discours du locuteur. Dans cette contribution, nous verrons comment le feedback du discours de candidature pour un troisième mandat de Ouattara en 2020 se structure en deux catégories quasi antagoniques : l’une validant l’argumentation et l’autre se posant en contre argumentation. Mots-clés : Argumentation ; Feedback ; Réfutation.

Résumé : Le Forum pour la Réconciliation Nationale en Côte d’Ivoire visait, comme stipulé par le triptyque qui le sous-tendait, la Vérité, la Repentance et le Pardon, afin d’aboutir à la Réconciliation. La question du pardon est donc centrale. Notre contribution ambitionne de montrer que par une étude des différentes sémiotisations du pardon, il est possible d’entrevoir que cette grande rencontre était vouée à l’échec. Mots-clés : Acte illocutionnaire, Pardon, Postures énonciatives, Stratégies argumentatives, Victimisation