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Abstract Background There have been many reports of tumor-to-tumor metastasis, in which cancer metastasizes directly into meningiomas. However, metastasis infiltrating tumors in which cancer metastasizes around meningiomas are rare. Therefore, we report a case of metastasis originating from lung cancer that infiltrated meningioma. Case presentation A 79-year-old Japanese woman underwent head magnetic resonance imaging for brain metastasis screening before lung cancer surgery. At that time, asymptomatic meningioma of the left frontal region was accidentally found. Magnetic resonance imaging 6 months later revealed a lesion suspected to be a metastatic brain tumor close to the meningioma. Brain tumor resection was performed, and histopathological diagnosis was meningioma and metastatic brain tumor. Metastatic cancer had invaded the meningioma at the boundary between the brain tumor and metastasis. Conclusions A sudden change in imaging findings on routine examination of meningiomas in patients with lung carcinoma may indicate a metastatic brain tumor. The form of cancer metastasis to meningioma is not limited to tumor-to-tumor metastasis, but also includes metastasis infiltrating tumors near the meningioma.

Abstract The automotive industry aims to ensure the cold-start capability of polymer electrolyte fuel cells (PEFCs) for developing fuel cell electric vehicles that can be driven in cold climates. Water and ice behavior is a key factor in maintaining this capability. Previously reported methods for visualizing water and/or ice are limited to small-sized PEFCs (

The Japan Meteorological Agency (JMA) has developed the third Japanese global atmospheric reanalysis, the Japanese Reanalysis for Three Quarters of a Century (JRA-3Q). The objective of JRA-3Q is to improve quality in terms of issues identified in the previous Japanese 55-year Reanalysis (JRA-55) and to extend the reanalysis period further into the past. JRA-3Q is based on the TL479 version of the JMA global Numerical Weather Prediction (NWP) system as of December 2018 and uses results of developments in the operational NWP system, boundary conditions, and forcing fields achieved at JMA since JRA-55. It covers the period from September 1947, when Typhoon Kathleen brought severe flood damage to Japan, and uses rescued historical observations to extend its analyses backwards in time about 10 years earlier than JRA-55. This paper describes the data assimilation system, forecast model, observations, boundary conditions, and forcing fields used to produce JRA-3Q as well as the basic characteristics of the JRA-3Q product. The initial quality evaluation revealed major improvements from JRA-55 in the global energy budget and representation of tropical cyclones (TCs). One of the major problems in JRA-55--global energy imbalance with excess upward net energy flux at the top of the atmosphere and at the surface--has been significantly reduced in JRA-3Q. Another problem--a trend of artificial weakening of TCs--has been resolved through the use of a method that generates TC bogus based on the JMA operational system. There remain several problems such that the volcanic-induced stratospheric warming is smaller than expected. This paper discusses the causes of such problems and possible solutions in future reanalyses. [ABSTRACT FROM AUTHOR]