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AbstractIntroductionMethodsResultsConclusionTransgender and gender diverse (TGD) people are disproportionately negatively impacted by gaps in several social determinants of health (SDH) domains.Using an SDH lens, this commentary leverages and reflects upon the expertise and experience of practitioners in the largest adult gender identity clinic in Canada providing services to TGD patients by facilitating access to gender-affirming healthcare.Perceived needs across SDH domains, efforts to address these needs, and recommendations for improving services and increasing access for TGD patients are shared.We argue that addressing SDH needs is a necessary and critical component of both comprehensive primary and mental healthcare for TGD individuals in particular, given the inequity many of them face across SDH domains. [ABSTRACT FROM AUTHOR]