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Comment cultiver facilement et en abondance des fruits et des légumes sains pour une communauté locale? Et comment le faire de manière écologique et résiliente en contribuant au renforcement des liens culturels, à l'éducation en matière d'agriculture durable et au maintien de la biodiversité? La réponse se trouve dans les systèmes agroforestiers multiétagés, mieux connus au Québec sous l'appellation de «forêts nourricières». S'autorégulant comme une forêt naturelle et exigeant un minimum d'entretien, ces systèmes sont des alliés de choix dans la révolution agroécologique en cours. Dans ce guide, Caroline Dufour-L'Arrivée met à profit son expertise pour outiller et accompagner les communautés qui souhaitent aménager des forêts nourricières dans leur milieu, qu'il soit urbain, rural, municipal, scolaire ou institutionnel. En plus d'offrir de nombreux conseils en matière de choix de végétaux et de techniques agricoles, ce guide: explique le concept de « forêt nourricière » et son importance; partage l'expérience acquise par treize initiatives modèles et pionnières du Québec sous la forme de portraits détaillés et illustrés; montre en quoi ce type d'aménagement permet aux collectivités de retisser des liens et de développer leur résilience; dégage les éléments fondamentaux dont il faut tenir compte pour mener à bien un projet de forêt nourricière collective; propose une méthode de travail étape par étape pour aider à structurer les démarches d'implantation de ce type de projets et suivre leur évolution. Les citoyen·nes expriment de plus en plus leur désir de développer une nouvelle agriculture saine et pérenne, moins laborieuse et créatrice d'espaces verts multifonctionnels. Ce guide saura assurément combler leur besoin d'accompagnement dans leur projet collectif.

Parents pauvres de nos aménagements paysagers ou de nos potagers, les arbres et arbustes indigènes recèlent pourtant un formidable potentiel. La coévolution avec les autres acteurs des écosystèmes en fait des plantes résistantes, résilientes et bien adaptées à nos conditions climatiques. Dans Arbres et arbustes indigènes pour les jardins du Québec, Bertrand Dumont identifie et dresse le portrait de plus de 130 plantes dont les qualités devraient les faire trôner en bonne place dans nos aménagements. Les conditions écologiques dans lesquelles elles vivent au naturel, leurs usages comestibles et leurs utilisations dans un jardin sont décrits dans un style précis et rigoureux. Des informations sur la manière dont ces végétaux doivent être sélectionnés, achetés, plantés et entretenus sont aussi présentées. Ce livre s'adresse à toutes les jardinières et tous les jardiniers qui croient que notre patrimoine végétal, aussi bien écologique, comestible que décoratif est important.

In a single volume Ernest Thompson Seton, renowned naturalist, writer, artist, and founding leader of the Boy Scouts of America, presents one of the most comprehensive guides to the outdoors ever written. Originally published in 1922 as The Book of Woodcraft, this work represents the culmination of years of observation and experience in the wilderness. Within these pages lie instructions and anecdotes—some expected, some delightfully unanticipated—regarding literally hundreds of arts, crafts, skills, and games. Here one can learn to distinguish edible plants from poisonous ones; start a fire using only a jackknife; build a four-store birdhouse out of a wooden box; communicate in sign language; tie a variety of essential knots; identify trees, wildflowers, animals, birds, and constellations; and much, much more.

Nature's remedies are all around, if you know what to look for. In Medicinal Herbs of Western Canada, award-winning author and artist Brenda Jones offers detailed advice on how to identify, collect, and prepare a variety of local wild herbs. Learn how to make a Calendula salve to help heal minor wounds, or how an oil made from the buds of Black Cottonwood trees can relax sore muscles. Make a decoction from Wild Licorice to soothe a sore throat or find out how an infusion of Valerian can calm the nerves and improve sleep. Through many courses, workshops, and extensive research, Jones has compiled this beautiful illustrated catalogue of healing herbs to help readers familiarize themselves with the medicines available in their own backyards. Covering 77 different plants, each with detailed, full-colour illustrations and accessible tips, facts, and recipes, this essential guide makes it easy to benefit from your neighbourhood's wild offerings. Includes a glossary of terms and a section on how to identify common poisonous plants and what to do if you encounter them.

Discover the meanings, powers, facts, and folklore for over 500 herbs and spices in The Complete Language of Herbs—now in a pocket-size edition for easy, on-the-go reference. Along with a beautiful visual depiction, each entry provides the herb or spice's scientific and common names, characteristics, and historic meanings and powers from mythology, medieval legends, folklore, and flower poetry. Did you know that allspice can be added to herbal mixtures to attract money or luck? Or that sprinkling arrowroot at the doors of your home will keep guests'negative energy from entering? Reaching the height of popularity during the Victorian era, floriographies—dictionaries of symbolic flower meanings—were an amusing pastime and art to subtly communicate unspoken emotions. To complement the success of The Complete Language of Flowers, author S. Theresa Dietz has scoured historic sources and compiled an equally beautiful compendium in The Complete Language of Herbs, revealing the secrets and powers of hundreds of common and forgotten herbs and spices from around the world. Together with stunning full-color illustrations and two indexes, one for searching by common herb and spice name and the other organized by meaning, this beautiful reference is a must-have for gardeners, chefs, party planners, and food enthusiasts.

A beautifully written and illustrated account of the threatened plant species that inhabit the British Isles.Britain and Ireland are home to around 300 species of rare flowering plants, and many more rare ferns, mosses, liverworts and freshwater algae. These are species at the cutting edge of biodiversity: fascinating, often beautiful, and in decline. Yet as some teeter on the brink, more rare species are still being discovered.In Rare Plants, prize-winning author Peter Marren describes the allure of Britain and Ireland's vanishing wild flora, from the simple joy of plant hunting to the wonder and (sometimes) weirdness of the plants themselves, as well as their important place in our landscape and culture. He also explores the condition of rarity in the context of our changing world and climate: why do plants become rare, what threats do they face, and what opportunities do we have to protect them before it is too late? The book concludes with an overview of different conservation techniques. Using test cases such as Lady's Slipper Orchid and Starved Wood-sedge, Peter asks: at what point does careful management becomes gardening? And how far are we are justified in intervening in the life of a wild species?Illustrated with around 300 colour images by some of Britain's best plant photographers, as well as boxed texts telling the fascinating stories of several key species, this is above all a celebration of rare plants and why they matter.

Many aspects of drug safety have become an outstanding and even persistent issue and may occur during the process of both drug discovery and development. Until 15 years ago, drug discovery and evaluation was primarily a sequential process starting with the selection of the most pharmacologically active compound from a series of newly synthesized small molecule chemical series by means of distinctive pharmacological assays. Safety aspects were addressed by evaluation of the selected compound at high doses in a series of specific studies directed at indications other than the intended indication of the new compound. These tests are then followed by pharmacokinetic studies, which are primarily conducted to confirm whether the selected compound possesses a suitable half-life for sufficient exposure and efficacy and, whether it has the desired properties specificity to the intended route of administration. Safety aspects relied predominantly on the conduct of single and repeat toxicologydose studies, which inform changes in organ structure rather than organ function. Both toxicological and pharmacokinetic studies are adapted to the progress of studies in clinical pharmacology and clinical trials. The new edition of this well and broadly accepted reference work contains several innovative and distinguished chapters. This'sequential'strategy has been abandoned with this new version of the book for several reasons: - Of the possible multitude of negative effects that novel drugs may impart on organ function, e.g. ventricular tachy-arrhythmia, many are detected too late in non-clinical studies to inform clinicians. On the other hand, negative findings in chronic toxicity studies in animals may turn out to be irrelevant for human beings. - New scientific approaches, e.g. high-throughput screening, human pluripotent stem cells, transgenic animals, knock-out animals, in silico models, pharmaco-genomics and pharmaco-proteomics, as well as Artificial Intelligence (AI) methods offered new possibilities. - There are several examples, that show that the'druggability'of compounds was considerably underestimated when the probability of success of a new project was assessed. The success rate in the pharmaceutical industry and the introduction of new chemical entities to the market per year dropped dramatically, whereas the development time for a new compound increased, sometimes exceeding the patent protection. Research and development scientists, involving the following changes, therefore adopted a change of strategy: - Parallel instead of sequential involvement of the various disciplines (multidimensional compound optimization). - The term'Safety Pharmacology'was coined. The International Conference on Harmonization (ICH) founded a Safety Pharmacology Working Group and the Safety Pharmacology Society (SPS) was launched. The discipline provided for evaluation, development and validation of a multitude of safety tests outlined in the'Core Battery of Studies'. - Characterizing the exposure profile of a drug by conducting pharmacokinetic studies that evaluates the absorption, distribution, metabolism and excretion should to be investigated at an early stage of development as results contribute to the selection of a compound for further development. Advancements in Toxicology were achieved by the introduction of new methods, e.g., in silico methods, genetic toxicology, computational toxicology and AI. The book is a landmark in the continuously changing world of drug research and developments. As such, it is essential reading for many groups: not only for all students of pharmacology and toxicology but also for industry scientists and physicians, especially those involved in clinical trials of drugs, and for pharmacists who must know the safety requirements of drugs. &nb

Encyclopedia of Quaternary Science, Third Edition, Six Volume Set brings together the multidisciplinary expertise needed to understand the history of humans, life, environmental, and climate change to understand what we may expect over the coming decades. Since publication of the previous edition, our understanding of many topics has been revolutionized by new discoveries and new techniques. The development of ancient DNA studies, for example, has revolutionized our thinking about the origins, dispersal, and population dynamics of our ancestors. Every new aDNA analysis from ancient human remains causes the story to become more complex. We are the sole survivors of the genus Homo, yet we harbor genetic fragments from other closely related but long-extinct lineages. The Quaternary is uniquely situated as a laboratory in which to study the shaping of the modern world, including biotic responses to large-scale environmental change. This new edition of this book is the most comprehensive account of state-of-the-art research in this field. - Revised and expanded, this new edition brings the science up-to-date by featuring advances in all the multi-disciplinary aspects of Quaternary science - Focuses new content on numerical modeling for paleoclimate and ice-sheet reconstructions, which have greatly advanced since publication of the Second Edition - Covers ancient DNA, which has revolutionized our knowledge of human origins and dispersals, plant and animal population genetics, and more - Includes short, structured chapters, which help readers finding the information they need and save time

As recent years have seen alarming declines of insect and bird populations in many states, more gardeners have discovered the importance of including native plants in order to nurture these pollinators and sustain local ecosystems. But when so many popular landscaping designs involve exotic cultivars and invasive plant species, how can you create a garden that is both aesthetically pleasing and ecologically responsible? In this fully revised second edition of the classic guide Designing Gardens with Flora of the American East, gardening expert Carolyn Summers draws on the most recent research on sustainable landscaping. She is joined in this edition by her daughter, landscape designer Kate Brittenham, offering an intergenerational dialogue about the importance of using indigenous plants that preserve insect and bird habitats. The practical information they provide is equally useful for home gardeners and professionals, including detailed descriptions of keystone trees, shrubs, perennials, vines, and grasses that are native to the eastern United States. Accompanied by entirely new illustrations and updated plant lists, they offer chic yet eco-friendly landscape designs fully customized for different settings, from suburban yards to corporate office parks. The states covered in this book are CT, DE, IA, IL, IN, KY, MA, MD, ME, MI, MN, MO, NC, NH, NJ, NY, OH, PA, RI, TN, VA, VT, WI, and WV, as well as southern Quebec and Ontario.

Winner of the National Book Award This bestselling, groundbreaking exploration of the Far North is a classic of natural history, anthropology, and travel writing.The Arctic is a perilous place. Only a few species of wild animals can survive its harsh climate. In this modern classic, Barry Lopez explores the many-faceted wonders of the Far North: its strangely stunted forests, its mesmerizing aurora borealis, its frozen seas. Musk oxen, polar bears, narwhal, and other exotic beasts of the region come alive through Lopez's passionate and nuanced observations. And, as he examines the history and culture of its indigenous communities, along with parallel narratives of intrepid, often underprepared and subsequently doomed polar explorers, Lopez drives to the heart of why the austere and formidable Arctic is also a constant source of breathtaking beauty, mystery, and wonder. Written in prose as pure as the land it describes, Arctic Dreams is a timeless mediation on the ability of the landscape to shape our dreams and to haunt our imaginations.

Nos lecteurs trouveront dans ce numéro de transition deux réflexions interreliées. L'une sur l'écriture de la Côte-Nord, et l'autre sur l'écriture du Labrador. D'abord, suivant ce mot de présentation, un important texte de Pierre Rouxel qui revient sur les objectifs et les défis du Groupe de recherche sur l'écriture nord-côtière (le GRÉNOC) et de la revue Littoral qu'il a contribué à fonder et qu'il a animés avec passion depuis maintenant vingt ans. Comment développer une recherche littéraire en région? Comment définir le corpus entier des textes qui abordent la Côte-Nord? Comment définir les paramètres formels, esthétiques et thématiques de «l'écriture nord-côtière» telle qu'elle se pratique aujourd'hui et telle qu'elle s'est pratiquée au cours de son histoire? Ces formidables défis, Pierre Rouxel les a relevés accompagné d'une équipe passionnée, tour à tour formée de Jérôme Guénette, Marie-Ève Vaillancourt, Donald Bherer et Monique Durand, et aujourd'hui, alors que Pierre Rouxel cède la codirection de ce vaisseau amiral de la littérature sur la Côte-Nord, de Johanne Charest - qui codirigera la revue avec moi à compter de ce printemps - et Gabrielle Lapierre. Ce numéro contient un dossier sur le Labrador, ce voisin nordique fascinant, méconnu et parfois si semblable à la Côte-Nord. En abordant «l'idée du Labrador», nous avons voulu tout à la fois réfléchir à la projection vers le Labrador, à ses écrits et à ses ambiguïtés, mais aussi à l'effet de miroir qu'il exerce sur la Côte-Nord et à la porosité qui existe entre ces deux territoires: deux géants définis par deux côtes qui se poursuivent l'une dans l'autre, des rives du fleuve Saint-Laurent à celles de l'Atlantique vers l'Arctique; deux fronts de mer qui ont fait peur, qui ont fasciné et résisté aux Européens qui arrivaient en Amérique, et qui se définissent tous les deux, ainsi que l'écrit Pierre Rouxel, comme «un pays dans le pays»: l'une s'inscrit dans le Québec quand l'autre est rattaché à Terre-Neuve. On trouvera dans ce dossier sur «La Côte-Nord et l'idée du Labrador» les réflexions de Monique Durand et de Pascal Chevrette sur l'imaginaire du Labrador; un texte de Louis-Jacques Dorais sur la continuité inuite et un autre de Paul Charest sur la continuité innue et la frontière entre le Labrador et la Côte-Nord; des études de Donald Bherer, de Stéfan Marchand et de Pierre Rouxel sur les pionniers de l'étude du Labrador ; une analyse du magazine Them Days, et de son rôle dans le développement de l'écriture labradorienne, ainsi qu'un hommage au géographe Henri Dorion. En plus de ce dossier, nos lecteurs trouveront les nouvelles de la vie littéraire de la Côte-Nord, des études sur des textes nord-côtiers et un grand nombre d'inédits, qui témoignent de la vitalité littéraire constante de la région. Daniel Chartier

Canadian Literature and Medicine breaks new ground by formulating a series of frameworks with which to read and interpret a national literature derived from the very fabric of that literature – in this case Canadian. Canadian literature is of particular interest because of its consideration of coloniality, Indigeneity, and coincident development alongside a nascent socialized medical system currently under threat from neoliberalism. The first chapters of the book carefully track the development of Canada's socialized medical system as it manifests in the imaginations of the nation's poets and authors who depict care. Reciprocal flows are investigated in which these poets and authors are quoted in policy documents. The archive-based methodology is sustained in subsequent chapters that rely upon a unique interdisciplinary mix of medical history, philosophy of medicine, medical policy, theory inherent to the field of Canadian literature (focusing in particular on the garrison mentality as a form of aesthetic protest and the feminist ethics of care), and Indigenous ways of knowing.