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In this study, for the very first time developing of n- and p-type 3-D single-channel (SC) FinFET and gate-all-around (GAA) Multi-Bridge-Channel FETs (MBCFET) like nanowire FET (NWFET) and nanosheet FET (NSFET) are benchmarked towards device and circuit levels which are emulated with International Road map for Devices and Systems (IRDS) for sub-5-nm technology nodes. Compared to the FinFET, the MBCFETs exhibits higher ON-current ( $I_{\mathrm {ON}})$ , switching ratio ( $I_{\mathrm {ON}}/I_{\mathrm {OFF}})$ , lower subthreshold-swing (SS) and drain-induced barrier lowering (DIBL). Except for extended parasitic capacitances ( $C_{\mathrm {para}})$ , our benchmarking results show that the NWFET and NSFET achieve the high-performance (HP) and low-power (LP) goals of IRDS. Furthermore, the NSFET delivers superior performance towards DC and analog/RF metrics. The cut-off frequency ( $f_{\mathrm {T}})$ and gain bandwidth product (GBW) are higher (because of high $I_{\mathrm {ON}})$ in the case of NSFET, even though the capacitive effect is significant. Further, the logic circuit applications like CMOS inverter and ring oscillator (RO) circuits are analyzed and compared in detail. The CMOS inverters propagation delays ( $\tau _{\mathrm {p}})$ is reduced to 31% from FinFET to NWFET and 12% from NWFET to NSFETs is noticed. Also, the NWFET and NSFET based ROs offer 39% and 56% high oscillation frequency ( $f_{\mathrm {osc}})$ compared to that of FinFET counterpart. Finally, the single stage current mirror performance and operational transconductance amplifiers (OTA) gain and common mode rejection ratio (CMRR) are carried out towards analog and mixed-mode circuit applications.

Sheath blight (ShB) is the most serious disease of rice (Oryza sativa L.), caused by the soil-borne fungus Rhizoctonia solani Kühn (R. solani). It poses a significant threat to global rice productivity, resulting in approximately 50% annual yield loss. Managing ShB is particularly challenging due to the broad host range of the pathogen, its necrotrophic nature, the emergence of new races, and the limited availability of highly resistant germplasm. In this study, we conducted QTL mapping using an F2 population derived from a cross between a partially resistant accession (IRGC81941A) of Oryza nivara and the susceptible rice cultivar Punjab rice 121 (PR121). Our analysis identified 29 QTLs for ShB resistance, collectively explaining a phenotypic variance ranging from 4.70 to 48.05%. Notably, a cluster of four QTLs (qRLH1.1, qRLH1.2, qRLH1.5, and qRLH1.8) on chromosome 1 consistently exhibit a resistant response against R. solani. These QTLs span from 0.096 to 420.1 Kb on the rice reference genome and contain several important genes, including Ser/Thr protein kinase, auxin-responsive protein, protease inhibitor/seed storage/LTP family protein, MLO domain-containing protein, disease-responsive protein, thaumatin-like protein, Avr9/Cf9-eliciting protein, and various transcription factors. Additionally, simple sequence repeats (SSR) markers RM212 and RM246 linked to these QTLs effectively distinguish resistant and susceptible rice cultivars, showing great promise for marker-assisted selection programs. Furthermore, our study identified pre-breeding lines in the advanced backcrossed population that exhibited superior agronomic traits and sheath blight resistance compared to the recurrent parent. These promising lines hold significant potential for enhancing the sheath blight resistance in elite cultivars through targeted improvement efforts.

A focussed ion beam can change the structural, morphological, and electrical properties of polymer composites. In this work mechanical mixing technique is used to develop CaCu3Ti4O12/CoFe2O4/epoxy composites with CCTO loading (50wt%, 35wt%, 25wt%, and 15wt%). These composites were irradiated with 120 MeV Au+ beam at a constant fluence of 6 × 1012 ions/cm2 and their dielectric, morphological properties were investigated. The comprehensive examination of results revealed significant changes in surface morphology (polymer degradation, and rifts). The dielectric constant and dielectric loss of prepared composites was found to be ~ 35 and ~ 1.2, respectively. The hardness of composites was observed ~ 99 after irradiation. Ion irradiation induced physiochemical changes due to solid-ion interaction, which improvise composites applicability in microelectronic devices, and electromagnetic shields. Moreover, the mechanism of solid-ion interaction is conferred in the text. [ABSTRACT FROM AUTHOR]

Although studies of the sacral corridor dimension have been reported in the European population, little attention has been paid to this issue in the Asian population. The purpose of the study is to estimate the safe dimension of the corridor to avoid neurovascular damage during the fixation of the sacral fracture. The study aimed to examine the cephalocaudal (vertical) and the anteroposterior diameter of the bony passage in the upper three sacral segments. The study further examines the effect of age and sex on corridor dimensions at different sacral levels. Three-dimensionally reconstructed sacra from computed tomography of normal subjects were included in the study. Cephalocaudal and anteroposterior diameters were measured in coronal and axial sections using Geomagic Freeform Plus software. Anteroposterior diameter of the sacral corridor at the first, second, and third sacral segments are significantly higher in males (P=0.013, 0.0011, and <0.0001, respectively). The length of the sacrum also revealed sexual dimorphism (P<0.00016). The anteroposterior diameter of the second sacral segment (ap-S2c) correlated moderately with the first sacral anteroposterior diameter (ap-S1c) (R=0.519, P<0.001). The ap-S2c exhibited a moderate correlation to the third sacral segment (ap-S3c) (R=0.677, P<0.001). The sacral corridor at the level of S1 has the largest cephalocaudal (18.25 mm) and anteroposterior diameter (17.11 mm). Placement of the screw in the first sacral corridor may avoid damage to the neurovascular bundle during the fixation of the sacral fracture. [ABSTRACT FROM AUTHOR]

This study reports the synthesis of barium-ferrite (BaFe2O4) particles by co-precipitation method, which is employed to prepare BaFe2O4/multiwall carbon nanotubes (MWCNTs)/epoxy nanocomposites. Furthermore, the structural properties, ferroelectric and dielectric properties, and electromagnetic attenuation properties are studied. The role of varying concentrations of BaFe2O4, frequency, and temperature on dielectric behavior is studied. In the presence of applied field, dielectric constant enhances as a result of interfacial polarization with increasing BaFe2O4 concentration. The permittivity is highest at low frequency and decreased with increasing frequency. With temperature, initially, dielectric constant increases and then decreases as a result of charge accumulation at interfaces and leads to interfacial polarization as confirmed by ferroelectric behavior. Here, BaFe2O4/MWCNTs/epoxy composite (with 40 phr BFO, where phr denotes parts per hundred) exhibited the highest value of saturation polarization (PS) ~0.31 µC/cm2 and low value of remanent polarization (Pr), that is ~0.009 µC/cm2. Moreover, composites exhibited high electromagnetic interference (EMI) shielding effectiveness (SE) of nearly 19 dB for 40 phr BaFe2O4 concentration at 11.3 GHz. Here, the reflection-dominated SE is ~1.06 dB and absorption-dominated SE is about 18.67 dB, which dominates the total SE. The absorption-dominant behavior is depicted by the BaFe2O4/MWCNTs/epoxy nanocomposites in EMI shielding as further conferred in the text. [ABSTRACT FROM AUTHOR]

Ca9Y(VO4)7 phosphor activated with Er3+ ions have been developed by the urea-aided solution combustion technique. XRD profiles assisted with Rietveld refinement executed over-developed Er3+-activated Ca9Y(VO4)7 powder, revealed a trigonal phase with the R3c space group. The electron microscope techniques namely TEM and SEM characterize the size and surface-linked qualities of the developed nanopowder, respectively. The uniform distribution of various elements in the nanocrystalline sample is authenticated by an energy-dispersive spectroscopy (EDS) system. The Eg (band gap) value of 3.64 eV for Ca9Y0.9Er0.1(VO4)7 and 3.74 eV for Ca9Y(VO4)7 has been estimated. Upon 382 nm excitation, Er3+: Ca9Y(VO4)7 phosphor gives rise to the bright green emission owing to the 4S3/2 → 4I15/2 transition. The concentration quenching after 10 mol% composition of trivalent erbium ions is attributed to dipole-dipole interlinkages in accordance with Dexter's theory. The radiative lifetime (1.1083 ms), non-radiative rates (0.2079 ms− 1), quantum efficiency (79%), along with colorimetric parameters i.e. CIE x (= 0.2577), y (= 0.4566), and CCT quantities offer Ca9Y0.9Er0.1(VO4)7 as a proficient green radiating nanomaterial for RGB phosphors in solid-state applications. [ABSTRACT FROM AUTHOR]

By tailoring and optimizing the structure of core or shell material, complete alteration of properties of the material can be obtained. Herein, we have reported synthesis of CaCu3Ti4O12@CoFe2O4 particles through the chemical co-precipitation route. CaCu3Ti4O12@CoFe2O4 particles consist of CaCu3Ti4O12 (~ 200 nm) as a core and CoFe2O4 as a shell of 2.5 nm. The prepared composites are characterized with appropriate characterization tools. The morphological results confirm the proper formation of core shell structure where CaCu3Ti4O12 and CoFe2O4 act as a core and shell, respectively. The greater CCTO content composites exhibited promising relative permittivity of 8.2 × 103 at 700 °C sintering temperature (8 h) at frequency 40 to 8 MHz. When CaCu3Ti4O12@CoFe2O4 undergoes heat treatment, it leads to the removal of oxalic acid. However, a weight loss of 8.3% is obtained for CCTO-coated composites that is quite low as compared to ~ 11% weight loss obtained in pristine CFO. The removal of organic groups significantly contributed to the increase in dielectric properties. These results imply that the development of CaCu3Ti4O12@CoFe2O4 core shell structure paves the wave for high-performance devices. [ABSTRACT FROM AUTHOR]

In this study, PPF dependent fixed point theorems are proved for a nonlinear operator, where the domain space C[[a,b], E] is distinct from the range space, E, which is a Strong Partial b-metric space (SPbMS). We obtain existence and uniqueness of PPF dependent fixed point results for the defined mappings under SPbMS. Our results are the extension of fixed point results in SPbMS. Examples are provided in the support of results. [ABSTRACT FROM AUTHOR]

Diversely substituted methoxy derivatives of arylpiperazinyl–alkyl benzothiazolone has been evaluated as specific probe for 5HT7. To determine the best methoxy derivative for 5HT7 receptor affinity, we synthesised a number of 2-benzothiazolone arylalkyl piperazine derivatives. In-vitro/vivo studies with C-2 substituted [11C]ABT showed 5HT7 specific binding. The radiochemical purity of [11C]ABT was found to be more than 99% with radiochemical stability persistence for more than 1.5 hr at 25 °C. The interaction of BSA and ABT has been analysed by photophysical studies for better understanding of properties such as adsortion, distribution, metabolism and elemination (ADME). The interaction between ABT and BSA was analyzed by using the UV-vis and fluorescence spectra. UV-vis spectra analyzed the changes in primary structure of BSA on its interaction with ABT. ABT showed quenched fluorescence emission intensity of tryptophan residues in BSA via static quenching mechanism. This study might help to understand how ABT binds to serum protein or subsequently to know the ADME of this drug candidate. [ABSTRACT FROM AUTHOR]

Ferrite/carbon (NiFe2O4/C) nanocomposite derived from metal–organic frameworks (MOF) has been evaluated as electrode material for supercapacitors. The ferrite/carbon hybrid has synthesized via one-step solvothermal method followed by heat treatment. The thermal treatment of the MOF has been conducted under different environments (N2 and air) at various temperatures, resulting in the formation of a porous diamond-shaped ferrite/carbon nanocomposite. Notably, the material subjected to pyrolysis at 500 °C in an N2 environment exhibits remarkable enhancements in its properties, showcasing the highest specific capacitance of 85.5 F g−1 at a current density of 0.25 A g−1. This excellent specific capacitance is attributed to surface redox reactions that take place due to the material's large active surface area. Asymmetric supercapacitor composed of NF500 and activated carbon has shown a high energy density of 69.2 Wh kg−1 at a power density of 180.07 W kg−1. These outstanding electrochemical properties make the synthesized hybrid material a highly promising candidate for various energy storage applications. [ABSTRACT FROM AUTHOR]

Introduction: The prevalence of treatment-related complications remains high throughout the course of cancer treatment resulting a decline in quality of life. Physiotherapy can have a positive influence on various domains of Quality of Life (QoL), potentially alleviating the severity of perceived complications. Aim: To evaluate the physiotherapy interventions used for managing treatment-related complications among breast cancer patients. Materials and Methods: Databases including Medical Literature Analysis and Retrieval System Online (MEDLINE), Science Direct, Cochrane Library, and Scopus from year 2000 to 2022 was searched with Mesh terms for trials with breast cancer patients>18 years of age participating in physiotherapy program. The primary outcome measure of interest was a significant improvement in treatment-related complications from pre- to post intervention. Change in quality of life was evaluated as secondary outcome measure. Cochrane risk of bias tool was used to assess the risk of bias and quality of included studies. Results: A total of 20 randomised controlled trials with 2019 patients incorporated various physiotherapy interventions to manage and alleviate treatment-related complications. For physical functioning (p=0.04) and the pain-sleep-fatigue cluster (p=0.006 to 0.044) different types of exercises were included. Complex Decongestive Therapy (CDT) combined with other electrotherapy modalities was embraced to manage lymphedema (p<0.05). For shoulder and arm dysfunction (p<0.05) passive stretching, mobilisation and strengthening exercises were incorporated. Furthermore, regular practice of exercise and physiotherapy exhibited positive impacts on overall health-related quality of life (p=0.0001 to 0.01) along with improvements in anxiety, depression, self-esteem and emotional function. Conclusion: Physiotherapy interventions are exceedingly effective in managing and providing relief from breast cancer treatment-related complications. Consequently, the integration of physiotherapy into cancer treatment protocols has the potential to enhance the overall QoL of patients. [ABSTRACT FROM AUTHOR]

Background: The glenopolar angle (GPA), usually ranges from 30° to 45°. GPA measures the tilt of the plane of the glenoid cavity in relation to the axis of the body of the scapula passing from the superior pole of the glenoid cavity to the inferior angle of the scapula. It is essential to assess the results of surgeries for dislocated shoulders. Worse long-term outcomes can arise from glenoid misalignment in scapular neck fractures. When evaluating prognosis and planning therapy for shoulder injuries including scapular fractures, GPA assessment is essential. Still, there is a dearth of data on the normal range of GPA and its contributing elements, which calls for more study. The purpose of this study is to determine typical GPA values by utilizing radiographs and a sizable sample of scapular bone specimens., Methods: In this study, the GPA was assessed in 50 chest radiographs of anteroposterior (AP) view and Neer's view of individuals as well as 100 dried scapulae of any gender. The mean GPA obtained using the various methods was then statistically compared., Findings: All scapulae had an average GPA of 42.6°. Twenty-nine scapulae had GPA observations higher than 45°, with an average of 47.2°. Twenty-seven scapulae had GPA measurements below 40°, averaging 37.3°. Right-sided 62 scapulae with an average GPA of 43.1° were present. Thirty-eight of left-side scapulae had a GPA of 41.7° on average. It was determined that the 1.6° mean difference in GPA between the two groups was not statistically significant. The Kolmogorov-Smirnov test verified that the GPA data had a normal distribution. The homogeneity of variances across various measuring techniques was confirmed using Levene's test. The average GPA measured using the dry scapula approach was 42.6°, the average GPA measured using the AP view was 39.8°, and the average GPA measured using the Neer I view was 42.3°. The GPA means from these three approaches differed considerably (p=0.0014) according to a one-way Analysis of Variance (ANOVA). Fisher's least significant difference post hoc testing showed that the scapular bone specimens and the Neer I view revealed significantly higher GPA values than AP shoulder radiographs. The GPA values obtained from the osteological group and the Neer I perspective had a mean difference of 0.21°, which was practically identical and suggested that there was no statistically significant difference between these approaches., In Summary: In order to diagnose and treat a variety of shoulder joint diseases, this study estimates the normal values of scapular GPA. Furthermore, it offers support for improved implant design in the context of Indian shoulder joint replacement and repair. Using every measurement technique, the GPA values on the right and left sides did not differ significantly. GPA results from various measuring methods varied significantly, which emphasizes the significance of methodological consistency in clinical and research settings., Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Institutional Ethical Committee issued approval 604/IEC/IGIMS dated 18/12/2018. I hereby affirm that the Institutional Ethical Committee or Ethics Committee has approved the research conducted for this article. The protocols and methodologies employed in this study have been carefully reviewed and deemed ethically sound in accordance with the established guidelines and regulations. Furthermore, all necessary permissions and consent procedures have been obtained from relevant participants or stakeholders involved in this research. The confidentiality and anonymity of participants have been rigorously maintained, and their rights and welfare have been upheld throughout the course of this study. This statement affirms the ethical integrity and compliance of the research conducted upholding the highest standards of ethical conduct. Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work., (Copyright © 2024, Kumari et al.)