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BackgroundCyberbullying significantly affects adolescents, increasing the risk of negative emotional symptoms. This study explores how psychological flexibility and inflexibility may mediate this relationship, focusing on adolescent mental health in the context of cyberbullying.MethodsA sample of 2,171 secondary school students, aged 11–18 years, was used to assess cyberbullying, emotional symptoms, and levels of psychological flexibility and inflexibility.ResultsCybervictimization showed a direct relationship with emotional symptoms and psychological inflexibility. Psychological flexibility was negatively associated with cybervictimization and positively associated with mental health, acting as a protective mediator against the association of cyberbullying.ConclusionPsychological flexibility emerges as a key factor in reducing the negative association of cybervictimization in adolescents. These findings highlight the importance of developing strategies to improve psychological flexibility in young people as a means to strengthen their resilience in the face of cyberbullying and its emotional consequences.

The dialysis membrane based on a hydrophilic polymer (Hydrolink NV) was designed to enhance the movement of adsorbed water at the blood–membrane interface, aiming to achieve antithrombogenic and antifouling effects. This study aimed to assess the performance and albumin loss of the Hydrolink NV dialyzer in hemodialysis (HD) and post-dilution hemodiafiltration (HDF) with different infusion flows (Qis) and compare it with the hydrophilic FX CorAL dialyzer in post-dilution HDF. A prospective study was carried out in 20 patients. Patients underwent five dialysis sessions with the same routine dialysis parameters: four sessions with the Toraylight NV 2.1 (HD, post-dilution HDF with 50, 75 or auto-substitution Qi) and one with the FX CorAL 800 (post-dilution HDF with auto-substitution Qi). The reduction ratios’ (RRs’) wide range of molecular weight molecules were assessed and the dialysate albumin loss was quantified. The lowest β2-microglobulin, indoxyl-sulfate, and p-cresyl sulfate RR values were observed with the Toraylight NV 2.1 in HD, and they improved progressively with an increased Qi, without differences being observed between the two dialyzers in auto-substitution. A different removal profile was observed in terms of myoglobin, kFLC, prolactin, α1-microglobulin, α1-acid glycoprotein, and λFLC, whose RRs also improved progressively with an increased Qi but were significantly higher with the Toraylight NV than the CorAL in the same convective condition. There were significant differences in the albumin dialysate losses, with the highest value obtained with the Toraylight NV in auto-substitution HDF, with more than 50% of patients surpassing 5 g per session. The Toraylight NV dialyzer has great potential for efficacy but should be used at the optimal convective volume (Qi not exceeding 75 mL/min or FF not exceeding 25%) to avoid excessive albumin loss.