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Solar wind prediction algorithms and simulations of coronal events often employ photospheric field maps that are assembled over a 27 day solar rotation. This has stimulated efforts to update and better synchronize the maps by applying flux transport and including observations of the back side of the Sun. Here, using potential-field source-surface extrapolations, we address the question of how the emergence of a large active region (AR) on the Sun’s farside affects the coronal field and configuration of coronal holes on the Earth-facing side. We find that, if the new AR is located ∼135°–180° in longitude from Earth, the effect on the coronal field and solar wind near the central meridian will be almost negligible. This is because, when sunspot activity is relatively low, the outermost AR loops will become connected to the nearby polar fields; when sunspot activity is high, the newly emerged flux will connect to neighboring ARs. However, large ARs that emerge near the solar limb may sometimes have a significant effect on the field near the central meridian. In particular, a coronal hole having opposite polarity to that of the nearest sector of the AR may partially close down, resulting in slower wind; conversely, if the coronal hole has the same polarity as the facing AR sector, it will tend to increase in areal size, resulting in faster wind. In most cases, the main effect of a new AR will be to redistribute open flux between itself and neighboring coronal holes (including the polar holes) through interchange reconnection.