1. Determinants and effects of microvascular obstruction on serial change in left ventricular diastolic function after reperfused acute myocardial infarction
- Author
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Hyemoon Chung, Jiwon Seo, In-Soo Kim, Chul Hwan Park, Jong-Youn Kim, Pil-Ki Min, Young Won Yoon, Byoung Kwon Lee, Tae-Hoon Kim, Bum-Kee Hong, Se-Joong Rim, Hyuck Moon Kwon, and Eui-Young Choi
- Subjects
acute myocardial infarction ,systolic function ,diastolic function ,microvascular obstruction ,cardiovascular magnetic resonance ,Diseases of the circulatory (Cardiovascular) system ,RC666-701 - Abstract
BackgroundAlthough left ventricular (LV) diastolic dysfunction is more related to functional capacity after acute myocardial infarction (AMI), the determinants of LV diastolic functional change after reperfused AMI remain unknown. This study aimed to investigate the effects of microvascular obstruction (MVO) on mid-term changes in LV diastolic function after reperfused AMI.MethodsIn a cohort of 72 AMI patients who underwent successful revascularization, echocardiography and cardiovascular magnetic resonance imaging were repeated at 9-month intervals. The late gadolinium enhancement (LGE) amount, segmental extracellular volume fraction, global LV, and left atrial (LA) phasic functions, along with mitral inflow and tissue Doppler measurements, were repeated.ResultsAmong the included patients, 31 (43%) patients had MVO. During the 9-month interval, LV ejection fraction (EF) and LV global longitudinal strain (GLS) were significantly improved in accordance with a decrease in LGE amount (from 18.2 to 10.3 g, p
- Published
- 2024
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