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Your search keyword '"Hansen, Kristian Schultz"' showing total 7 results
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1. Impact of smoking in patients with suspected coronary artery disease in the randomised DISCHARGE trial

Author

Mancone, Massimo, Mézquita, Aldo J. Vázquez, Birtolo, Lucia Ilaria, Maurovich-Horvat, Pal, Kofoed, Klaus F., Benedek, Theodora, Donnelly, Patrick, Rodriguez-Palomares, Jose, Erglis, Andrejs, Štěchovský, Cyril, Šakalytė, Gintare, Ađić, Nada Čemerlić, Gutberlet, Matthias, Diez, Ignacio, Davis, Gershan, Zimmermann, Elke, Kępka, Cezary, Vidakovic, Radosav, Francone, Marco, Ilnicka-Suckiel, Małgorzata, Plank, Fabian, Knuuti, Juhanni, Faria, Rita, Schröder, Stephen, Berry, Colin, Saba, Luca, Ruzsics, Balazs, Rieckmann, Nina, Kubiak, Christine, Hansen, Kristian Schultz, Müller-Nordhorn, Jaqueline, Merkely, Bela, Sigvardsen, Per E., Benedek, Imre, Orr, Clare, Valente, Filipa Xavier, Zvaigzne, Ligita, Suchánek, Vojtěch, Jankauskas, Antanas, Ađić, Filip, Woinke, Michael, Keane, Stephen, Lecumberri, Ignacio, Thwaite, Erica, Kruk, Mariusz, Jovanovic, Vladimir, Kuśmierz, Donata, Feuchtner, Gudren, Pietilä, Mikko, Ribeiro, Vasco Gama, Drosch, Tanja, Delles, Christian, Palmisano, Vitanio, Fisher, Michael, Drobni, Zsófia D., Kragelund, Charlotte, Aurelian, Rosca, Kelly, Stephanie, del Blanco, Bruno Garcia, Rubio, Ainhoa, Boussoussou, Melinda, Hove, Jens D., Rodean, Ioana, Regan, Susan, Calabria, Hug Cuéllar, Becker, Dávid, Larsen, Linnea, Hodas, Roxana, Napp, Adriane E., Haase, Robert, Feger, Sarah, Mohamed, Mahmoud, Neumann, Konrad, Dreger, Henryk, Rief, Matthias, Wieske, Viktoria, Douglas, Pamela S., Estrella, Melanie, Bosserdt, Maria, Martus, Peter, Serna-Higuita, Lina M., Dodd, Jonathan D., and Dewey, Marc

Published
2024
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2. Erratum. Computed Tomography Versus Invasive Coronary Angiography in Patients With Diabetes and Suspected Coronary Artery Disease. Diabetes Care 2023;46:2015–2023

Author

Benedek, Theodora, primary, Wieske, Viktoria, additional, Szilveszter, Bálint, additional, Kofoed, Klaus F., additional, Donnelly, Patrick, additional, Rodriguez-Palomares, José, additional, Erglis, Andrejs, additional, Veselka, Josef, additional, Šakalytė, Gintarė, additional, Ađić, Nada Čemerlić, additional, Gutberlet, Matthias, additional, Diez, Ignacio, additional, Davis, Gershan, additional, Zimmermann, Elke, additional, Kępka, Cezary, additional, Vidakovic, Radosav, additional, Francone, Marco, additional, Ilnicka-Suckiel, Małgorzata, additional, Plank, Fabian, additional, Knuuti, Juhani, additional, Faria, Rita, additional, Schröder, Stephen, additional, Berry, Colin, additional, Saba, Luca, additional, Ruzsics, Balazs, additional, Rieckmann, Nina, additional, Kubiak, Christine, additional, Hansen, Kristian Schultz, additional, Müller-Nordhorn, Jacqueline, additional, Merkely, Bela, additional, Sigvardsen, Per E., additional, Benedek, Imre, additional, Orr, Clare, additional, Valente, Filipa Xavier, additional, Zvaigzne, Ligita, additional, Horváth, Martin, additional, Jankauskas, Antanas, additional, Ađić, Filip, additional, Woinke, Michael, additional, Mulvihill, Niall, additional, Lecumberri, Iñigo, additional, Thwaite, Erica, additional, Laule, Michael, additional, Kruk, Mariusz, additional, Stefanovic, Milica, additional, Mancone, Massimo, additional, Kuśmierz, Donata, additional, Feuchtner, Gudrun, additional, Pietilä, Mikko, additional, Ribeiro, Vasco Gama, additional, Drosch, Tanja, additional, Delles, Christian, additional, Melis, Marco, additional, Fisher, Michael, additional, Boussoussou, Melinda, additional, Kragelund, Charlotte, additional, Aurelian, Rosca, additional, Kelly, Stephanie, additional, Blanco, Bruno Garcia del, additional, Rubio, Ainhoa, additional, Károlyi, Mihály, additional, Hove, Jens D., additional, Rodean, Ioana, additional, Regan, Susan, additional, Calabria, Hug Cuéllar, additional, Gellér, László, additional, Larsen, Linnea, additional, Hodas, Roxana, additional, Napp, Adriane E., additional, Haase, Robert, additional, Feger, Sarah, additional, Mohamed, Mahmoud, additional, Serna-Higuita, Lina M., additional, Neumann, Konrad, additional, Dreger, Henryk, additional, Rief, Matthias, additional, Danesh, John, additional, Estrella, Melanie, additional, Bosserdt, Maria, additional, Martus, Peter, additional, Dodd, Jonathan D., additional, and Dewey, Marc, additional

Published
2024
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4. Age and Computed Tomography and Invasive Coronary Angiography in Stable Chest Pain: A Prespecified Secondary Analysis of the DISCHARGE Randomized Clinical Trial

Author

Bosserdt, Maria, Serna-Higuita, Lina M., Feuchtner, Gudrun, Merkely, Bela, Kofoed, Klaus F., Benedek, Theodora, Donnelly, Patrick, Rodriguez-Palomares, José, Erglis, Andrejs, Štechovský, Cyril, Šakalyte, Gintare, Adic, Nada Cemerlic, Gutberlet, Matthias, Dodd, Jonathan D., Diez, Ignacio, Davis, Gershan, Zimmermann, Elke, Kepka, Cezary, Vidakovic, Radosav, Francone, Marco, Ilnicka-Suckiel, Malgorzata, Plank, Fabian, Knuuti, Juhani, Faria, Rita, Schröder, Stephen, Berry, Colin, Saba, Luca, Ruzsics, Balazs, Rieckmann, Nina, Kubiak, Christine, Hansen, Kristian Schultz, Müller-Nordhorn, Jacqueline, Szilveszter, Bálint, Sigvardsen, Per E., Benedek, Imre, Orr, Clare, Valente, Filipa Xavier, Zvaigzne, Ligita, Suchánek, Vojtech, Jankauskas, Antanas, Adic, Filip, Woinke, Michael, Hensey, Mark, Lecumberri, Iñigo, Thwaite, Erica, Laule, Michael, Kruk, Mariusz, Neskovic, Aleksandar N., Mancone, Massimo, Kusmierz, Donata, Pietilä, Mikko, Ribeiro, Vasco Gama, Drosch, Tanja, Delles, Christian, Porcu, Maurizio, Fisher, Michael, Boussoussou, Melinda, Kragelund, Charlotte, Aurelian, Rosca, Kelly, Stephanie, Garcia del Blanco, Bruno, Rubio, Ainhoa, Maurovich-Horvat, Pál, Hove, Jens D., Rodean, Ioana, Regan, Susan, Cuellar-Calabria, Hug, Molnár, Levente, Larsen, Linnea, Hodas, Roxana, Napp, Adriane E., Haase, Robert, Feger, Sarah, Mohamed, Mahmoud, Neumann, Konrad, Dreger, Henryk, Rief, Matthias, Wieske, Viktoria, Estrella, Melanie, Martus, Peter, Sox, Harold C., and Dewey, Marc

Abstract

IMPORTANCE: The effectiveness and safety of computed tomography (CT) and invasive coronary angiography (ICA) in different age groups is unknown. OBJECTIVE: To determine the association of age with outcomes of CT and ICA in patients with stable chest pain. DESIGN, SETTING, AND PARTICIPANTS: The assessor-blinded Diagnostic Imaging Strategies for Patients With Stable Chest Pain and Intermediate Risk of Coronary Artery Disease (DISCHARGE) randomized clinical trial was conducted between October 2015 and April 2019 in 26 European centers. Patients referred for ICA with stable chest pain and an intermediate probability of obstructive coronary artery disease were analyzed in an intention-to-treat analysis. Data were analyzed from July 2022 to January 2023. INTERVENTIONS: Patients were randomly assigned to a CT-first strategy or a direct-to-ICA strategy. MAIN OUTCOMES AND MEASURES: MACE (ie, cardiovascular death, nonfatal myocardial infarction, or stroke) and major procedure-related complications. The primary prespecified outcome of this secondary analysis of age was major adverse cardiovascular events (MACE) at a median follow-up of 3.5 years. RESULTS: Among 3561 patients (mean [SD] age, 60.1 [10.1] years; 2002 female [56.2%]), 2360 (66.3%) were younger than 65 years, 982 (27.6%) were between ages 65 to 75 years, and 219 (6.1%) were older than 75 years. The primary outcome was MACE at a median (IQR) follow-up of 3.5 (2.9-4.2) years for 3523 patients (99%). Modeling age as a continuous variable, age, and randomization group were not associated with MACE (hazard ratio, 1.02; 95% CI, 0.98-1.07; P for interaction = .31). Age and randomization group were associated with major procedure-related complications (odds ratio, 1.15; 95% CI, 1.05-1.27; P for interaction = .005), which were lower in younger patients. CONCLUSIONS AND RELEVANCE: Age did not modify the effect of randomization group on the primary outcome of MACE but did modify the effect on major procedure-related complications. Results suggest that CT was associated with a lower risk of major procedure-related complications in younger patients. TRIAL REGISTRATION: ClinicalTrials.gov Identifier: NCT02400229

Published
2024
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5. Coronary Artery Calcium Score Predicts Major Adverse Cardiovascular Events in Stable Chest Pain

Author

Biavati, Federico, Saba, Luca, Boussoussou, Melinda, Kofoed, Klaus F., Benedek, Theodora, Donnelly, Patrick, Rodríguez-Palomares, José, Erglis, Andrejs, Štěchovský, Cyril, Šakalytė, Gintarė, Čemerlić Ađić, Nada, Gutberlet, Matthias, Dodd, Jonathan D., Diez, Ignacio, Davis, Gershan, Zimmermann, Elke, Kępka, Cezary, Vidakovic, Radosav, Francone, Marco, Ilnicka-Suckiel, Małgorzata, Plank, Fabian, Knuuti, Juhani, Faria, Rita, Schröder, Stephen, Berry, Colin, Ruzsics, Balazs, Rieckmann, Nina, Kubiak, Christine, Hansen, Kristian Schultz, Müller-Nordhorn, Jacqueline, Maurovich-Horvat, Pál, Sigvardsen, Per E., Benedek, Imre, Orr, Clare, Valente, Filipa Xavier, Zvaigzne, Ligita, Suchánek, Vojtěch, Jankauskas, Antanas, Ađić, Filip, Woinke, Michael, Cadogan, Diarmaid, Lecumberri, Iñigo, Thwaite, Erica, Kruk, Mariusz, Neskovic, Aleksandar N., Mancone, Massimo, Kuśmierz, Donata, Feuchtner, Gudrun, Pietilä, Mikko, Ribeiro, Vasco Gama, Drosch, Tanja, Delles, Christian, Cau, Riccardo, Fisher, Michael, Merkely, Bela, Kragelund, Charlotte, Aurelian, Rosca, Kelly, Stephanie, Blanco, Bruno García del, Rubio, Ainhoa, Szilveszter, Bálint, Hove, Jens D., Rodean, Ioana, Regan, Susan, Cuéllar Calabria, Hug, Édes, István Ferenc, Larsen, Linnea, Hodas, Roxana, Napp, Adriane E., Haase, Robert, Feger, Sarah, Mohamed, Mahmoud, Serna-Higuita, Lina M., Neumann, Konrad, Dreger, Henryk, Rief, Matthias, Wieske, Viktoria, Budoff, Matthew J., Estrella, Melanie, Martus, Peter, Bosserdt, Maria, and Dewey, Marc

Abstract

In participants with stable chest pain referred for invasive coronary angiography, those with a coronary artery calcium score of 0 at CT had very low, while higher scores had increasing occurrence of major adverse cardiovascular events.

Published
2024
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6. Effect of Body Mass Index on Effectiveness of CT versus Invasive Coronary Angiography in Stable Chest Pain: The DISCHARGE Trial

Author

Sykes, Robert, Collison, Damien, Merkely, Bela, Kofoed, Klaus F., Donnelly, Patrick, Rodríguez-Palomares, José, Erglis, Andrejs, Veselka, Josef, Šakalytė, Gintarė, Ađić, Nada Čemerlić, Gutberlet, Matthias, Dodd, Jonathan D., Diez, Ignacio, Davis, Gershan, Zimmermann, Elke, Kępka, Cezary, Vidakovic, Radosav, Francone, Marco, Ilnicka-Suckiel, Małgorzata, Plank, Fabian, Knuuti, Juhani, Faria, Rita, Schröder, Stephen, Berry, Colin, Saba, Luca, Ruzsics, Balazs, Rieckmann, Nina, Kubiak, Christine, Hansen, Kristian Schultz, Müller-Nordhorn, Jacqueline, Maurovich-Horvat, Pál, Knudsen, Andreas D., Benedek, Imre, Orr, Clare, Valente, Filipa Xavier, Zvaigzne, Ligita, Horváth, Martin, Jankauskas, Antanas, Ađić, Filip, Woinke, Michael, Keane, Stephen, Lecumberri, Iñigo, Thwaite, Erica, Laule, Michael, Kruk, Mariusz, Zivanic, Aleksandra, Mancone, Massimo, Kuśmierz, Donata, Feuchtner, Gudrun, Pietilä, Mikko, Ribeiro, Vasco Gama, Drosch, Tanja, Delles, Christian, Porcu, Michele, Fisher, Michael, Bárány, Tamás, Sørum, Charlotte, Aurelian, Rosca, Kelly, Stephanie, Blanco, Bruno Garcia del, Rubio, Ainhoa, Szilveszter, Bálint, Abdulla, Jawdat, Rodean, Ioana, Regan, Susan, Calabria, Hug Cuéllar, Vecsey-Nagy, Milán, Jurlander, Birgit, Hodas, Roxana, Feger, Sarah, Mohamed, Mahmoud, Serna-Higuita, Lina M., Neumann, Konrad, Dreger, Henryk, Rief, Matthias, Wieske, Viktoria, Ferencik, Maros, Estrella, Melanie, Bosserdt, Maria, Martus, Peter, Benedek, Theodora, and Dewey, Marc

Abstract

When patients suspected of having coronary artery disease were stratified by body mass index category, no difference in clinical outcomes was observed between those who underwent initial management with CT and those who underwent invasive coronary angiography.

Published
2024
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7. The labor market costs of work-related stress: A longitudinal study of 52 763 Danish employees using multi-state modeling.

Author

Pedersen J, Graversen BK, Hansen KS, and Madsen IEH

Subjects
Male, Humans, Female, Longitudinal Studies, Denmark, Unemployment, Occupational Stress epidemiology, Psychological Tests, Self Report
Abstract

Objective: Work-related stress is an important public health concern in all industrialized countries and is linked to reduced labor market affiliation and an increased disease burden. We aimed to quantify the labor market costs of work-related stress for a large sample of Danish employees., Methods: We linked four consecutive survey waves on occupational health and five national longitudinal registers with date-based information on wage and social benefits payments. From 2012 to 2020, we followed survey participants for two year-periods, yielding 110 559 person-years. We identified work stress by combining three dichotomous stress indicators: (i) self-perceived work stress, (ii) Cohen 4-level perceived stress scale, and (iii) job strain. Using the multi-state expected labor market affiliation (ELMA) method, we estimated the labor market expenses associated with work-related stress., Results: Of the employees, 26-37% had at least one work-stress indicator. Men aged 35-64 years and women aged 18-64 years with work-related stress had up to 81.6 fewer workdays and up to 50.7 more days of sickness absence during follow-up than similarly aged men without work stress. The average annual work absenteeism loss per employee linked to work-related stress was €1903 for men and €3909 for women, corresponding to 3.3% of men's average annual wages and 9.0% of women's average annual wages, respectively. The total annual expenses were €305.2 million for men and €868.5 million for women., Conclusion: Work-related stress was associated with significant labor market costs due to increased sickness absence and unemployment. The prevention of work-related stress is an important occupational health concern, and the development of effective interventions should be given high priority.

Published
2024
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